Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 55524228 . G A CCDS603.1:NM_174936.3:c.1411Gcc>Acc_NP_777596.2:p.471A>T Homo sapiens proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p4e 1 Q8NBP7 99.71 0.0 X-RAY
 2007-04-10 ALA A:471 NA:NA DO NA DO DO DO NA NA NA
ALA B:471 A:471 4.0 0.035 -60.2 139.3 NA NA NA
6u2f 1 Q8NBP7 99.71 0.0 X-RAY
 2020-02-05 ALA A:471 A:471 12.0 0.104 -75.4 140.4 12.0 0.104 0.0
5vlp 1 Q8NBP7 99.71 0.0 X-RAY
 2017-08-16 ALA A:471 A:471 16.0 0.139 -66.0 143.0 16.0 0.139 0.0
6u3i 1 Q8NBP7 99.71 0.0 X-RAY
 2020-02-05 ALA A:471 A:471 16.0 0.139 -74.0 149.4 16.0 0.139 0.0
6u26 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 ALA A:441 NA:NA DO NA DO DO DO NA NA NA
ALA B:441 B:471 13.0 0.113 -67.5 139.8 NA NA NA
6u2n 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 ALA A:441 NA:NA DO NA DO DO DO NA NA NA
ALA B:441 B:471 5.0 0.043 -69.5 141.2 5.0 0.043 0.0 HOH
 5.424
 N
 O
6u2p 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 ALA A:441 NA:NA DO NA DO DO DO NA NA NA
ALA B:441 B:471 7.0 0.061 -58.9 140.6 7.0 0.061 0.0 HOH
 7.608
 O
 O
6u36 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 ALA A:441 NA:NA DO NA DO DO DO NA NA NA
ALA B:441 B:471 11.0 0.096 -66.9 147.1 11.0 0.096 0.0
6u38 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 ALA A:441 NA:NA DO NA DO DO DO NA NA NA
ALA B:441 B:471 12.0 0.104 -68.8 152.4 12.0 0.104 0.0 HOH
 7.929
 C
 O
6u3x 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 ALA A:441 NA:NA DO NA DO DO DO NA NA NA
ALA B:441 B:471 51.0 0.443 S -74.0 117.1 51.0 0.443 0.0
2pmw 2 Q5SZQ2 100.0 0.0 X-RAY
 2007-05-08 ALA B:319 B:471 7.0 0.061 -66.3 137.6 7.0 0.061 0.0 HOH
 3.783
 CB
 O
3p5b 2 Q8NBP7 99.81 0.0 X-RAY
 2011-10-26 ALA B:319 A:471 5.0 0.043 -73.1 137.1 5.0 0.043 0.0
3p5c 2 Q8NBP7 99.81 0.0 X-RAY
 2011-10-26 ALA B:319 A:471 5.0 0.043 -73.1 137.0 5.0 0.043 0.0
3bps 2 Q8NBP7 99.63 0.0 X-RAY
 2008-02-12 ALA B:319 A:471 14.0 0.122 -69.6 142.8 14.0 0.122 0.0 HOH
 9.501
 N
 O
3gcw 2 Q8NBP7 99.63 0.0 X-RAY
 2009-03-03 ALA B:319 A:471 12.0 0.104 -66.0 136.9 12.0 0.104 0.0
3gcx 2 Q8NBP7 99.63 0.0 X-RAY
 2009-03-03 ALA B:319 A:471 14.0 0.122 -70.0 141.7 14.0 0.122 0.0
3sqo 1 Q8NBP7 99.63 0.0 X-RAY
 2012-05-16 ALA A:319 A:471 6.0 0.052 -77.9 119.9 6.0 0.052 0.0 HOH
 3.040
 CA
 O
4ne9 1 Q8NBP7 99.63 0.0 X-RAY
 2014-09-10 ALA A:319 A:471 9.0 0.078 -62.6 139.8 9.0 0.078 0.0
ALA B:319 B:471 9.0 0.078 -62.0 139.9 NA NA NA
4k8r 2 Q8NBP7 99.63 0.0 X-RAY
 2013-05-08 ALA B:319 B:471 6.0 0.052 -51.3 137.9 6.0 0.052 0.0 HOH
 6.396
 CA
 O
5vl7 2 Q8NBP7 99.63 0.0 X-RAY
 2017-08-16 ALA B:319 B:471 120.0 1.0 360.0 130.7 120.0 1.0 0.0
2qtw 2 Q8NBP7 99.63 0.0 X-RAY
 2007-09-18 ALA B:319 B:471 5.0 0.043 -69.5 140.8 5.0 0.043 0.0 HOH
 3.607
 CB
 O
7kev 2 Q8NBP7 99.63 0.0 X-RAY
 2021-11-24 ALA B:319 B:471 6.0 0.052 -139.1 127.6 6.0 0.052 0.0
7kfa 2 Q8NBP7 99.63 0.0 X-RAY
 2021-11-10 ALA B:319 B:471 12.0 0.104 -63.6 133.0 12.0 0.104 0.0
3m0c 2 Q8NBP7 99.44 0.0 X-RAY
 2011-03-16 ALA B:319 B:471 4.0 0.035 -69.5 140.7 4.0 0.035 0.0
3h42 2 Q8NBP7 99.26 0.0 X-RAY
 2009-05-05 ALA B:319 B:471 13.0 0.113 -72.3 139.6 13.0 0.113 0.0 HOH
 8.519
 C
 O
5oca 2 Q8NBP7 99.26 0.0 X-RAY
 2017-09-20 ALA B:319 B:471 18.0 0.157 -78.3 145.6 18.0 0.157 0.0 HOH
 3.593
 O
 O
7anq 1 Q8NBP7 100.0 6e-167 X-RAY
 2021-10-20 ALA A:20 A:471 11.0 0.096 -69.9 122.8 11.0 0.096 0.0 HOH
 5.941
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8nbp7-f1 1 Q8NBP7 100.0 0.0 ALA A:471 A:471 12.0 0.104 -61.7 141.7