Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 55525165 . G A CCDS603.1:NM_174936.3:c.1510Ggg>Agg_NP_777596.2:p.504G>R Homo sapiens proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p4e 1 Q8NBP7 99.71 0.0 X-RAY
 2007-04-10 GLY A:504 NA:NA DO NA DO DO DO NA NA NA
GLY B:504 A:504 92.0 1.0 S 68.7 34.3 NA NA NA
6u2f 1 Q8NBP7 99.71 0.0 X-RAY
 2020-02-05 GLY A:504 A:504 85.0 1.0 T 75.7 47.1 85.0 1.0 0.0
5vlp 1 Q8NBP7 99.71 0.0 X-RAY
 2017-08-16 GLY A:504 A:504 85.0 1.0 T 66.9 46.7 85.0 1.0 0.0
6u3i 1 Q8NBP7 99.71 0.0 X-RAY
 2020-02-05 GLY A:504 A:504 87.0 1.0 T 70.7 35.4 87.0 1.0 0.0
6u26 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 GLY A:474 NA:NA DO NA DO DO DO NA NA NA
GLY B:474 B:504 80.0 1.0 T 93.3 11.6 NA NA NA
6u2n 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 GLY A:474 NA:NA DO NA DO DO DO NA NA NA
GLY B:474 B:504 94.0 1.0 S 56.7 33.7 94.0 1.0 0.0 HOH
 8.897
 O
 O
6u2p 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 GLY A:474 NA:NA DO NA DO DO DO NA NA NA
GLY B:474 B:504 80.0 1.0 T 56.5 38.1 80.0 1.0 0.0 HOH
 8.682
 O
 O
6u36 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 GLY A:474 NA:NA DO NA DO DO DO NA NA NA
GLY B:474 B:504 84.0 1.0 T 77.4 -130.1 84.0 1.0 0.0
6u38 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 GLY A:474 NA:NA DO NA DO DO DO NA NA NA
GLY B:474 B:504 91.0 1.0 S 71.5 27.6 91.0 1.0 0.0
6u3x 1 Q8NBP7 99.7 0.0 X-RAY
 2019-11-06 GLY A:474 NA:NA DO NA DO DO DO NA NA NA
GLY B:474 B:504 84.0 1.0 T 64.5 29.2 84.0 1.0 0.0 HOH
 8.817
 C
 O
2pmw 2 Q5SZQ2 100.0 0.0 X-RAY
 2007-05-08 GLY B:352 B:504 94.0 1.0 T 67.7 7.9 94.0 1.0 0.0 HOH
 7.473
 C
 O
3p5b 2 Q8NBP7 99.81 0.0 X-RAY
 2011-10-26 GLY B:352 A:504 90.0 1.0 S 67.9 33.4 90.0 1.0 0.0
3p5c 2 Q8NBP7 99.81 0.0 X-RAY
 2011-10-26 GLY B:352 A:504 89.0 1.0 S 67.9 33.5 89.0 1.0 0.0
3bps 2 Q8NBP7 99.63 0.0 X-RAY
 2008-02-12 GLY B:352 A:504 86.0 1.0 T 71.5 31.9 86.0 1.0 0.0 HOH
 5.513
 C
 O
3gcw 2 Q8NBP7 99.63 0.0 X-RAY
 2009-03-03 GLY B:352 A:504 86.0 1.0 T 64.8 44.1 86.0 1.0 0.0
3gcx 2 Q8NBP7 99.63 0.0 X-RAY
 2009-03-03 GLY B:352 A:504 87.0 1.0 T 65.4 43.6 87.0 1.0 0.0
3sqo 1 Q8NBP7 99.63 0.0 X-RAY
 2012-05-16 GLY A:352 A:504 85.0 1.0 S 64.1 42.1 85.0 1.0 0.0
4ne9 1 Q8NBP7 99.63 0.0 X-RAY
 2014-09-10 GLY A:352 A:504 89.0 1.0 S 70.7 36.4 89.0 1.0 0.0
GLY B:352 B:504 86.0 1.0 T 70.3 38.8 NA NA NA
4k8r 2 Q8NBP7 99.63 0.0 X-RAY
 2013-05-08 GLY B:352 B:504 91.0 1.0 S 62.1 32.7 91.0 1.0 0.0 HOH
 4.626
 N
 O
5vl7 2 Q8NBP7 99.63 0.0 X-RAY
 2017-08-16 GLY B:352 B:504 86.0 1.0 S 65.9 47.5 86.0 1.0 0.0
2qtw 2 Q8NBP7 99.63 0.0 X-RAY
 2007-09-18 GLY B:352 B:504 89.0 1.0 T 55.7 37.7 89.0 1.0 0.0 HOH
 8.611
 O
 O
7kev 2 Q8NBP7 99.63 0.0 X-RAY
 2021-11-24 GLY B:352 B:504 95.0 1.0 T 59.8 20.8 95.0 1.0 0.0
7kfa 2 Q8NBP7 99.63 0.0 X-RAY
 2021-11-10 GLY B:352 B:504 90.0 1.0 S 64.7 31.2 90.0 1.0 0.0
3m0c 2 Q8NBP7 99.44 0.0 X-RAY
 2011-03-16 GLY B:352 B:504 90.0 1.0 T 55.6 37.8 90.0 1.0 0.0
3h42 2 Q8NBP7 99.26 0.0 X-RAY
 2009-05-05 GLY B:352 B:504 87.0 1.0 T 56.8 39.0 87.0 1.0 0.0
5oca 2 Q8NBP7 99.26 0.0 X-RAY
 2017-09-20 GLY B:352 B:504 86.0 1.0 T 56.3 49.4 86.0 1.0 0.0 HOH
 8.052
 O
 O
7anq 1 Q8NBP7 100.0 6e-167 X-RAY
 2021-10-20 GLY A:53 A:504 82.0 1.0 T 65.5 43.0 82.0 1.0 0.0 HOH
 2.785
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8nbp7-f1 1 Q8NBP7 100.0 0.0 GLY A:504 A:504 88.0 1.0 T 67.3 35.9