Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 949377 | . | C | A | CCDS6.1:NM_005101.3:c.17aCg>aAg_NP_005092.1:p.6T>K | Homo sapiens ISG15 ubiquitin-like modifier (ISG15), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3r66 | 2 | P05161 | 100.0 | 6e-113 |
X-RAY |
2011-06-08 | THR | C:13 | C:6 | 21.0 | 0.15 | E | -93.5 | 123.5 | 21.0 | 0.15 | 0.0 |
HOH |
8.140 |
N |
O |
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| THR | D:13 | D:6 | 19.0 | 0.136 | E | -93.3 | 122.7 | 19.0 | 0.136 | 0.0 |
HOH |
7.478 |
O |
O |
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| 3sdl | 2 | P05161 | 100.0 | 6e-113 |
X-RAY |
2011-07-20 | THR | C:13 | C:6 | 18.0 | 0.129 | E | -100.2 | 124.0 | 18.0 | 0.129 | 0.0 |
HOH |
7.694 |
N |
O |
||
| THR | D:13 | D:6 | 18.0 | 0.129 | E | -104.5 | 121.4 | 18.0 | 0.129 | 0.0 |
HOH |
2.777 |
OG1 |
O |
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| 7rbs | 2 | P05161 | 100.0 | 3e-112 |
X-RAY |
2021-09-29 | THR | B:8 | B:6 | 19.0 | 0.136 | E | -99.8 | 125.7 | 19.0 | 0.136 | 0.0 | ||||||
| THR | D:8 | D:6 | 21.0 | 0.15 | E | -93.9 | 128.9 | NA | NA | NA | |||||||||||||
| THR | F:8 | F:6 | 21.0 | 0.15 | E | -83.6 | 135.9 | NA | NA | NA | |||||||||||||
| THR | H:8 | H:6 | 28.0 | 0.2 | E | -88.6 | 116.8 | NA | NA | NA | |||||||||||||
| THR | J:8 | J:6 | 24.0 | 0.171 | E | -86.1 | 133.6 | NA | NA | NA | |||||||||||||
| 7s6p | 1 | P05161 | 100.0 | 3e-112 |
X-RAY |
2021-09-22 | THR | A:8 | A:6 | 22.0 | 0.157 | E | -89.5 | 129.0 | 22.0 | 0.157 | 0.0 |
HOH |
2.625 |
OG1 |
O |
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| THR | B:8 | B:6 | 25.0 | 0.179 | E | -90.6 | 129.0 | NA | NA | NA | |||||||||||||
| THR | C:8 | C:6 | 21.0 | 0.15 | E | -90.3 | 128.0 | NA | NA | NA | |||||||||||||
| THR | D:8 | D:6 | 26.0 | 0.186 | E | -90.3 | 128.3 | NA | NA | NA | |||||||||||||
| THR | E:8 | E:6 | 21.0 | 0.15 | E | -91.1 | 129.3 | NA | NA | NA | |||||||||||||
| THR | F:8 | F:6 | 27.0 | 0.193 | E | -91.4 | 128.8 | NA | NA | NA | |||||||||||||
| 3rt3 | 1 | P05161 | 99.37 | 4e-112 |
X-RAY |
2011-07-13 | THR | A:6 | B:6 | 21.0 | 0.15 | E | -93.5 | 127.5 | 21.0 | 0.15 | 0.0 |
HOH |
7.572 |
CA |
O |
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| 6bi8 | 2 | P05161 | 99.36 | 9e-111 |
X-RAY |
2018-11-07 | THR | C:6 | C:6 | 39.0 | 0.279 | -178.6 | 144.0 | 39.0 | 0.279 | 0.0 | |||||||
| THR | D:6 | D:6 | 29.0 | 0.207 | E | -78.2 | 146.4 | NA | NA | NA | |||||||||||||
| 3pse | 2 | P05161 | 98.72 | 3e-110 |
X-RAY |
2011-01-19 | THR | B:6 | B:6 | 39.0 | 0.279 | E | -92.7 | 135.5 | 39.0 | 0.279 | 0.0 | ||||||
| 1z2m | 1 | P05161 | 99.35 | 4e-110 |
X-RAY |
2005-05-24 | THR | A:6 | A:6 | 25.0 | 0.179 | E | -94.0 | 129.2 | 25.0 | 0.179 | 0.0 |
OS4 HOH |
9.331 7.913 |
CG2 N |
OS O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05161-f1 | 1 | P05161 | 100.0 | 2e-119 | THR | A:6 | A:6 | 12.0 | 0.086 | E | -88.3 | 115.9 | |