Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 949634 . C A CCDS6.1:NM_005101.3:c.274Cgc>Agc_NP_005092.1:p.92R>S Homo sapiens ISG15 ubiquitin-like modifier (ISG15), mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3r66 2 P05161 100.0 6e-113 X-RAY
 2011-06-08 ARG C:99 C:92 130.0 0.578 -84.6 110.4 130.0 0.578 0.0 HOH
 3.765
 NH2
 O
ARG D:99 D:92 135.0 0.6 -84.8 110.3 135.0 0.6 0.0 HOH
 4.091
 CG
 O
3sdl 2 P05161 100.0 6e-113 X-RAY
 2011-07-20 ARG C:99 C:92 130.0 0.578 -85.6 114.6 130.0 0.578 0.0 HOH
 2.761
 NH2
 O
ARG D:99 D:92 143.0 0.636 -78.9 113.3 143.0 0.636 0.0 HOH
 3.760
 CG
 O
7rbs 2 P05161 100.0 3e-112 X-RAY
 2021-09-29 ARG B:94 B:92 132.0 0.587 -74.8 96.1 132.0 0.587 0.0
ARG D:94 D:92 129.0 0.573 -93.9 102.3 NA NA NA
ARG F:94 F:92 126.0 0.56 -82.6 104.3 NA NA NA
ARG H:94 H:92 128.0 0.569 -92.1 105.2 NA NA NA
ARG J:94 J:92 133.0 0.591 -80.4 99.7 NA NA NA
7s6p 1 P05161 100.0 3e-112 X-RAY
 2021-09-22 ARG A:94 A:92 146.0 0.649 -89.7 122.5 146.0 0.649 0.0 HOH
 4.697
 NE
 O
ARG B:94 B:92 163.0 0.724 -87.7 123.5 NA NA NA
ARG C:94 C:92 162.0 0.72 -87.1 123.3 NA NA NA
ARG D:94 D:92 179.0 0.796 -89.1 121.8 NA NA NA
ARG E:94 E:92 145.0 0.644 -88.3 123.0 NA NA NA
ARG F:94 F:92 144.0 0.64 -88.6 122.3 NA NA NA
3rt3 1 P05161 99.37 4e-112 X-RAY
 2011-07-13 ARG A:92 B:92 135.0 0.6 -74.2 126.2 135.0 0.6 0.0 HOH
 2.812
 NH2
 O
6bi8 2 P05161 99.36 9e-111 X-RAY
 2018-11-07 ARG C:92 C:92 135.0 0.6 -97.7 120.9 135.0 0.6 0.0 HOH
 2.805
 O
 O
ARG D:92 D:92 140.0 0.622 -103.2 136.9 NA NA NA
3pse 2 P05161 98.72 3e-110 X-RAY
 2011-01-19 ARG B:92 B:92 180.0 0.8 -104.6 124.4 180.0 0.8 0.0 GOL
HOH
 5.590
2.730
 N
O
 O2
O
1z2m 1 P05161 99.35 4e-110 X-RAY
 2005-05-24 ARG A:92 A:92 164.0 0.729 -79.4 130.9 164.0 0.729 0.0 HOH
 2.763
 O
 O
3phx 2 P05161 100.0 5e-52 X-RAY
 2011-02-02 ARG B:15 B:92 125.0 0.556 -91.4 124.7 125.0 0.556 0.0 HOH
 2.696
 NH2
 O
6xa9 2 P05161 100.0 5e-52 X-RAY
 2020-06-17 ARG B:15 B:92 135.0 0.6 -85.3 126.6 135.0 0.6 0.0 HOH
 9.983
 C
 O
ARG D:15 D:92 54.0 NA -89.7 122.0 NA NA NA
ARG F:15 F:92 56.0 NA -90.2 121.8 NA NA NA
5tl6 2 P05161 100.0 5e-51 X-RAY
 2017-05-03 ARG C:14 C:92 138.0 0.613 -92.0 139.6 NA NA NA
ARG D:14 A:92 189.0 0.84 -123.1 138.3 189.0 0.84 0.0 HOH
 2.644
 NE
 O
5w8t 1 P05161 100.0 5e-51 X-RAY
 2017-09-27 ARG A:14 B:92 139.0 0.618 -92.3 121.8 139.0 0.618 0.0 HOH
 6.610
 C
 O
ARG C:14 D:92 125.0 0.556 -93.0 123.0 NA NA NA
5w8u 2 P05161 100.0 5e-51 X-RAY
 2017-09-27 ARG B:14 B:92 176.0 0.782 -97.3 126.9 176.0 0.782 0.0 HOH
 2.987
 O
 O
ARG D:14 D:92 137.0 0.609 -94.5 128.2 NA NA NA
6ffa 2 P05161 100.0 2e-50 X-RAY
 2018-02-21 ARG B:15 B:92 134.0 0.596 -91.8 129.5 134.0 0.596 0.0 HOH
 2.810
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05161-f1 1 P05161 100.0 2e-119 ARG A:92 A:92 168.0 0.747 -82.6 130.0