Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 949739 . G A CCDS6.1:NM_005101.3:c.379Gag>Aag_NP_005092.1:p.127E>K Homo sapiens ISG15 ubiquitin-like modifier (ISG15), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3r66 2 P05161 100.0 6e-113 X-RAY
 2011-06-08 GLU C:134 C:127 152.0 0.8 T 53.1 47.3 152.0 0.8 0.0 HOH
 5.669
 CG
 O
GLU D:134 D:127 149.0 0.784 T 52.1 46.6 149.0 0.784 0.0 HOH
 3.819
 N
 O
3sdl 2 P05161 100.0 6e-113 X-RAY
 2011-07-20 GLU C:134 C:127 155.0 0.816 T 55.0 46.4 155.0 0.816 0.0 HOH
 6.100
 CG
 O
GLU D:134 D:127 147.0 0.774 T 59.8 33.8 147.0 0.774 0.0 HOH
 4.186
 N
 O
7rbs 2 P05161 100.0 3e-112 X-RAY
 2021-09-29 GLU B:129 B:127 163.0 0.858 T 55.1 46.4 121.0 0.637 0.221 A:P0DTC1:0.221
 HOH
 9.195
 C
 O
GLU D:129 D:127 161.0 0.847 T 52.3 45.7 NA NA NA
GLU F:129 F:127 166.0 0.874 T 52.1 46.3 NA NA NA
GLU H:129 H:127 160.0 0.842 T 59.0 46.4 NA NA NA
GLU J:129 J:127 164.0 0.863 T 53.2 49.1 NA NA NA
7s6p 1 P05161 100.0 3e-112 X-RAY
 2021-09-22 GLU A:129 A:127 160.0 0.842 T 45.5 41.3 160.0 0.842 0.0 HOH
 4.591
 OE2
 O
GLU B:129 B:127 157.0 0.826 T 46.3 41.3 NA NA NA
GLU C:129 C:127 167.0 0.879 T 46.4 40.5 NA NA NA
GLU D:129 D:127 158.0 0.832 T 46.2 42.0 NA NA NA
GLU E:129 E:127 160.0 0.842 T 47.3 41.2 NA NA NA
GLU F:129 F:127 166.0 0.874 T 46.2 41.0 NA NA NA
3rt3 1 P05161 99.37 4e-112 X-RAY
 2011-07-13 GLU A:127 B:127 165.0 0.868 T 44.3 45.6 165.0 0.868 0.0 SIN
HOH
 7.785
3.700
 OE2
OE2
 O2
O
6bi8 2 P05161 99.36 9e-111 X-RAY
 2018-11-07 GLU C:127 C:127 139.0 0.732 T 41.9 53.9 42.0 0.221 0.511 A:K4LC41:0.511
 GOL
GOL
HOH
 4.128
7.266
2.549
 CA
O
OE1
 O3
H11
O
GLU D:127 D:127 140.0 0.737 T 44.7 52.6 NA NA NA
3pse 2 P05161 98.72 3e-110 X-RAY
 2011-01-19 GLU B:127 B:127 146.0 0.768 T 44.2 48.0 146.0 0.768 0.0 HOH
 2.697
 OE1
 O
1z2m 1 P05161 99.35 4e-110 X-RAY
 2005-05-24 GLU A:127 A:127 152.0 0.8 T 48.9 43.7 152.0 0.8 0.0 HOH
 3.382
 N
 O
3phx 2 P05161 100.0 5e-52 X-RAY
 2011-02-02 GLU B:50 B:127 159.0 0.837 T 48.9 44.5 159.0 0.837 0.0 HOH
 2.692
 OE2
 O
6xa9 2 P05161 100.0 5e-52 X-RAY
 2020-06-17 GLU B:50 B:127 169.0 0.889 T 50.5 37.9 129.0 0.679 0.21 A:P0DTD1:0.211
 HOH
 4.060
 CA
 O
GLU D:50 D:127 166.0 0.874 T 55.2 45.2 NA NA NA
GLU F:50 F:127 107.0 NA T 55.2 46.4 NA NA NA
5tl6 2 P05161 100.0 5e-51 X-RAY
 2017-05-03 GLU C:49 C:127 153.0 0.805 T 54.8 49.2 NA NA NA
GLU D:49 A:127 166.0 0.874 T 56.8 39.2 146.0 0.768 0.106 A:P0C6X7:0.105
 HOH
 9.205
 O
 O
5w8t 1 P05161 100.0 5e-51 X-RAY
 2017-09-27 GLU A:49 B:127 153.0 0.805 T 56.6 37.1 74.0 0.389 0.416 B:K0BWD0:0.416
 MPD
 3.963
 CA
 CM
GLU C:49 D:127 158.0 0.832 T 50.8 43.3 NA NA NA
5w8u 2 P05161 100.0 5e-51 X-RAY
 2017-09-27 GLU B:49 B:127 160.0 0.842 T 52.1 41.6 80.0 0.421 0.421 A:K0BWD0:0.421
 MPD
HOH
 3.623
3.119
 CA
N
 C1
O
GLU D:49 D:127 159.0 0.837 T 51.9 41.0 NA NA NA
6ffa 2 P05161 100.0 2e-50 X-RAY
 2018-02-21 GLU B:50 B:127 171.0 0.9 T 53.6 36.1 168.0 0.884 0.016 A:P03305:0.016
 HOH
 2.899
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05161-f1 1 P05161 100.0 2e-119 GLU A:127 A:127 153.0 0.805 T 49.3 33.5