Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 949781 . G A CCDS6.1:NM_005101.3:c.421Ggc>Agc_NP_005092.1:p.141G>S Homo sapiens ISG15 ubiquitin-like modifier (ISG15), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3r66 2 P05161 100.0 6e-113 X-RAY
 2011-06-08 GLY C:148 C:141 39.0 0.52 T 56.1 51.2 39.0 0.52 0.0 HOH
 3.793
 CA
 O
GLY D:148 D:141 35.0 0.467 T 56.3 51.8 35.0 0.467 0.0 HOH
 3.230
 CA
 O
3sdl 2 P05161 100.0 6e-113 X-RAY
 2011-07-20 GLY C:148 C:141 38.0 0.507 T 51.5 56.7 38.0 0.507 0.0 HOH
 3.589
 CA
 O
GLY D:148 D:141 46.0 0.613 T 60.6 33.9 46.0 0.613 0.0 HOH
 3.167
 C
 O
7rbs 2 P05161 100.0 3e-112 X-RAY
 2021-09-29 GLY B:143 B:141 32.0 0.427 T 57.0 51.7 32.0 0.427 0.0
GLY D:143 D:141 42.0 0.56 T 57.0 38.8 NA NA NA
GLY F:143 F:141 36.0 0.48 55.0 46.8 NA NA NA
GLY H:143 H:141 45.0 0.6 T 62.9 36.7 NA NA NA
GLY J:143 J:141 34.0 0.453 T 62.6 48.2 NA NA NA
7s6p 1 P05161 100.0 3e-112 X-RAY
 2021-09-22 GLY A:143 A:141 41.0 0.547 T 67.4 26.4 41.0 0.547 0.0 HOH
 3.376
 C
 O
GLY B:143 B:141 34.0 0.453 T 71.3 26.1 NA NA NA
GLY C:143 C:141 38.0 0.507 T 69.7 26.7 NA NA NA
GLY D:143 D:141 35.0 0.467 T 73.4 23.1 NA NA NA
GLY E:143 E:141 35.0 0.467 T 71.9 25.4 NA NA NA
GLY F:143 F:141 42.0 0.56 T 71.6 26.4 NA NA NA
3rt3 1 P05161 99.37 4e-112 X-RAY
 2011-07-13 GLY A:141 B:141 26.0 0.347 T 64.0 40.5 26.0 0.347 0.0 SIN
HOH
 3.697
3.498
 CA
CA
 O1
O
6bi8 2 P05161 99.36 9e-111 X-RAY
 2018-11-07 GLY C:141 C:141 43.0 0.573 T 60.9 34.4 43.0 0.573 0.0 HOH
 3.160
 C
 O
GLY D:141 D:141 44.0 0.587 T 59.9 38.4 NA NA NA
3pse 2 P05161 98.72 3e-110 X-RAY
 2011-01-19 GLY B:141 B:141 39.0 0.52 T 74.8 36.5 39.0 0.52 0.0 HOH
 3.279
 C
 O
1z2m 1 P05161 99.35 4e-110 X-RAY
 2005-05-24 GLY A:141 A:141 46.0 0.613 T 57.2 42.4 46.0 0.613 0.0 HOH
 3.823
 CA
 O
3phx 2 P05161 100.0 5e-52 X-RAY
 2011-02-02 GLY B:64 B:141 42.0 0.56 T 71.6 27.6 42.0 0.56 0.0 HOH
 4.596
 N
 O
6xa9 2 P05161 100.0 5e-52 X-RAY
 2020-06-17 GLY B:64 B:141 56.0 0.747 T 69.2 25.6 56.0 0.747 0.0
GLY D:64 D:141 56.0 0.747 62.5 58.8 NA NA NA
GLY F:64 F:141 62.0 0.827 T 62.8 58.6 NA NA NA
5tl6 2 P05161 100.0 5e-51 X-RAY
 2017-05-03 GLY C:63 C:141 50.0 0.667 67.6 57.9 NA NA NA
GLY D:63 A:141 29.0 0.387 T 71.3 34.8 29.0 0.387 0.0 HOH
 5.997
 N
 O
5w8t 1 P05161 100.0 5e-51 X-RAY
 2017-09-27 GLY A:63 B:141 51.0 0.68 T 79.4 27.5 51.0 0.68 0.0
GLY C:63 D:141 51.0 0.68 T 74.3 41.4 NA NA NA
5w8u 2 P05161 100.0 5e-51 X-RAY
 2017-09-27 GLY B:63 B:141 50.0 0.667 T 68.0 33.3 50.0 0.667 0.0 MPD
HOH
 9.266
3.506
 O
CA
 O2
O
GLY D:63 D:141 54.0 0.72 T 66.7 27.9 NA NA NA
6ffa 2 P05161 100.0 2e-50 X-RAY
 2018-02-21 GLY B:64 B:141 53.0 0.707 T 75.0 27.0 53.0 0.707 0.0 HOH
 3.493
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05161-f1 1 P05161 100.0 2e-119 GLY A:141 A:141 44.0 0.587 T 66.9 35.1