Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 949800 . C A CCDS6.1:NM_005101.3:c.440aCc>aAc_NP_005092.1:p.147T>N Homo sapiens ISG15 ubiquitin-like modifier (ISG15), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3r66 2 P05161 100.0 6e-113 X-RAY
 2011-06-08 THR C:154 C:147 36.0 0.257 E -104.6 116.0 36.0 0.257 0.0 HOH
 2.705
 N
 O
THR D:154 D:147 37.0 0.264 E -103.0 113.4 37.0 0.264 0.0 HOH
 2.793
 O
 O
3sdl 2 P05161 100.0 6e-113 X-RAY
 2011-07-20 THR C:154 C:147 40.0 0.286 E -111.1 105.9 40.0 0.286 0.0 HOH
 2.701
 N
 O
THR D:154 D:147 40.0 0.286 E -90.1 122.6 40.0 0.286 0.0 HOH
 2.780
 O
 O
7rbs 2 P05161 100.0 3e-112 X-RAY
 2021-09-29 THR B:149 B:147 36.0 0.257 E -114.3 107.6 36.0 0.257 0.0
THR D:149 D:147 38.0 0.271 E -99.4 115.0 NA NA NA
THR F:149 F:147 47.0 0.336 E -106.2 117.0 NA NA NA
THR H:149 H:147 42.0 0.3 E -102.0 122.9 NA NA NA
THR J:149 J:147 52.0 0.371 E -105.1 111.8 NA NA NA
7s6p 1 P05161 100.0 3e-112 X-RAY
 2021-09-22 THR A:149 A:147 39.0 0.279 E -107.7 128.4 39.0 0.279 0.0 HOH
 5.053
 N
 O
THR B:149 B:147 44.0 0.314 E -107.2 128.7 NA NA NA
THR C:149 C:147 37.0 0.264 E -107.4 127.6 NA NA NA
THR D:149 D:147 32.0 0.229 E -106.1 127.9 NA NA NA
THR E:149 E:147 46.0 0.329 E -105.3 128.7 NA NA NA
THR F:149 F:147 39.0 0.279 E -108.7 128.3 NA NA NA
3rt3 1 P05161 99.37 4e-112 X-RAY
 2011-07-13 THR A:147 B:147 51.0 0.364 E -113.5 120.7 51.0 0.364 0.0 HOH
 2.988
 OG1
 O
6bi8 2 P05161 99.36 9e-111 X-RAY
 2018-11-07 THR C:147 C:147 37.0 0.264 E -108.5 116.4 12.0 0.086 0.178 A:K4LC41:0.179
 GOL
HOH
 6.276
2.694
 O
OG1
 H31
O
THR D:147 D:147 38.0 0.271 E -103.7 120.7 NA NA NA
3pse 2 P05161 98.72 3e-110 X-RAY
 2011-01-19 THR B:147 B:147 55.0 0.393 E -103.7 118.1 55.0 0.393 0.0 GOL
HOH
 6.347
2.843
 CG2
OG1
 O2
O
1z2m 1 P05161 99.35 4e-110 X-RAY
 2005-05-24 THR A:147 A:147 37.0 0.264 E -112.0 123.2 37.0 0.264 0.0 HOH
 2.879
 N
 O
3phx 2 P05161 100.0 5e-52 X-RAY
 2011-02-02 THR B:70 B:147 42.0 0.3 E -106.2 127.0 42.0 0.3 0.0 HOH
 2.580
 OG1
 O
6xa9 2 P05161 100.0 5e-52 X-RAY
 2020-06-17 THR B:70 B:147 40.0 0.286 E -110.8 118.3 40.0 0.286 0.0 HOH
 4.029
 OG1
 O
THR D:70 D:147 49.0 0.35 E -104.4 112.9 NA NA NA
THR F:70 F:147 63.0 0.45 E -103.3 111.5 NA NA NA
5tl6 2 P05161 100.0 5e-51 X-RAY
 2017-05-03 THR C:69 C:147 43.0 0.307 E -112.3 115.9 NA NA NA
THR D:69 A:147 44.0 0.314 E -112.6 105.7 31.0 0.221 0.093 A:P0C6X7:0.093
 HOH
 3.160
 OG1
 O
5w8t 1 P05161 100.0 5e-51 X-RAY
 2017-09-27 THR A:69 B:147 40.0 0.286 E -106.3 110.8 15.0 0.107 0.179 B:K0BWD0:0.179
 ZN
MPD
HOH
 9.624
4.033
3.234
 OG1
O
OG1
 ZN
C1
O
THR C:69 D:147 42.0 0.3 E -112.8 107.4 NA NA NA
5w8u 2 P05161 100.0 5e-51 X-RAY
 2017-09-27 THR B:69 B:147 39.0 0.279 E -106.1 110.3 15.0 0.107 0.172 A:K0BWD0:0.171
 MPD
HOH
 4.253
2.739
 O
OG1
 O2
O
THR D:69 D:147 42.0 0.3 E -107.9 110.2 NA NA NA
6ffa 2 P05161 100.0 2e-50 X-RAY
 2018-02-21 THR B:70 B:147 43.0 0.307 E -111.2 124.4 43.0 0.307 0.0 HOH
 2.623
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05161-f1 1 P05161 100.0 2e-119 THR A:147 A:147 48.0 0.343 E -98.0 113.4