Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 949818 . G A CCDS6.1:NM_005101.3:c.458cGc>cAc_NP_005092.1:p.153R>H Homo sapiens ISG15 ubiquitin-like modifier (ISG15), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3r66 2 P05161 100.0 6e-113 X-RAY
 2011-06-08 ARG C:160 C:153 119.0 0.529 -82.7 174.1 119.0 0.529 0.0 HOH
 2.742
 NH2
 O
ARG D:160 D:153 118.0 0.524 -83.4 173.8 118.0 0.524 0.0 HOH
 2.510
 NH1
 O
3sdl 2 P05161 100.0 6e-113 X-RAY
 2011-07-20 ARG C:160 C:153 108.0 0.48 -79.2 -170.4 108.0 0.48 0.0 HOH
 2.787
 NH2
 O
ARG D:160 D:153 132.0 0.587 -121.3 159.1 132.0 0.587 0.0 HOH
 2.666
 NH1
 O
7rbs 2 P05161 100.0 3e-112 X-RAY
 2021-09-29 ARG B:155 B:153 87.0 0.387 -88.6 113.9 32.0 0.142 0.245 A:P0DTC1:0.244
 HOH
 5.833
 NH2
 O
ARG D:155 D:153 82.0 0.364 -82.5 117.4 NA NA NA
ARG F:155 F:153 85.0 0.378 -88.5 111.9 NA NA NA
ARG H:155 H:153 84.0 0.373 -102.1 116.2 NA NA NA
ARG J:155 J:153 86.0 0.382 -102.5 114.6 NA NA NA
7s6p 1 P05161 100.0 3e-112 X-RAY
 2021-09-22 ARG A:155 A:153 191.0 0.849 -60.4 360.0 191.0 0.849 0.0 HOH
 7.646
 NH1
 O
ARG B:155 B:153 185.0 0.822 -62.9 360.0 NA NA NA
ARG C:155 C:153 202.0 0.898 -71.9 360.0 NA NA NA
ARG D:155 NA:NA DO NA DO DO DO NA NA NA
ARG E:155 E:153 197.0 0.876 -66.2 360.0 NA NA NA
ARG F:155 F:153 181.0 0.804 -81.9 360.0 NA NA NA
3rt3 1 P05161 99.37 4e-112 X-RAY
 2011-07-13 ARG A:153 B:153 104.0 0.462 -78.8 119.3 104.0 0.462 0.0 SIN
HOH
 3.459
4.338
 NH2
NH1
 O1
O
6bi8 2 P05161 99.36 9e-111 X-RAY
 2018-11-07 ARG C:153 C:153 127.0 0.564 -84.2 104.5 23.0 0.102 0.462 A:K4LC41:0.462
 PGE
AYE
PGE
HOH
 6.714
9.995
2.538
2.821
 NH2
O
O
O
 H62
HN1
H2
O
ARG D:153 D:153 125.0 0.556 -77.7 98.3 NA NA NA
3pse 2 P05161 98.72 3e-110 X-RAY
 2011-01-19 ARG B:153 B:153 145.0 0.644 -88.4 118.7 32.0 0.142 0.502 A:Q6TQF5:0.502
 GOL
HOH
 8.713
2.938
 N
NH2
 O1
O
1z2m 1 P05161 99.35 4e-110 X-RAY
 2005-05-24 ARG A:153 A:153 153.0 0.68 -78.1 44.3 153.0 0.68 0.0 HOH
 3.860
 NH1
 O
3phx 2 P05161 100.0 5e-52 X-RAY
 2011-02-02 ARG B:76 B:153 141.0 0.627 -93.0 123.3 28.0 0.124 0.503 A:Q6TQR6:0.502
 HOH
 2.646
 O
 O
6xa9 2 P05161 100.0 5e-52 X-RAY
 2020-06-17 ARG B:76 B:153 83.0 0.369 -101.9 138.5 27.0 0.12 0.249 A:P0DTD1:0.249
ARG D:76 D:153 85.0 0.378 -110.3 134.3 NA NA NA
ARG F:76 F:153 95.0 0.422 -104.6 125.8 NA NA NA
5tl6 2 P05161 100.0 5e-51 X-RAY
 2017-05-03 ARG C:75 C:153 122.0 0.542 -83.6 148.5 NA NA NA
ARG D:75 A:153 123.0 0.547 -90.0 126.9 37.0 0.164 0.383 A:P0C6X7:0.382
 HOH
 6.067
 NH2
 O
5w8t 1 P05161 100.0 5e-51 X-RAY
 2017-09-27 ARG A:75 B:153 128.0 0.569 -82.3 104.6 28.0 0.124 0.445 B:K0BWD0:0.444
 HOH
 4.500
 NH1
 O
ARG C:75 D:153 134.0 0.596 -88.9 102.7 NA NA NA
5w8u 2 P05161 100.0 5e-51 X-RAY
 2017-09-27 ARG B:75 B:153 139.0 0.618 -96.5 104.8 26.0 0.116 0.502 A:K0BWD0:0.502
 HOH
 2.785
 NH1
 O
ARG D:75 D:153 137.0 0.609 -92.6 100.5 NA NA NA
6ffa 2 P05161 100.0 2e-50 X-RAY
 2018-02-21 ARG B:76 B:153 122.0 0.542 -81.1 116.2 48.0 0.213 0.329 A:P03305:0.329
 GOL
GOL
HOH
 7.393
3.787
2.699
 NH2
CD
O
 O1
O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05161-f1 1 P05161 100.0 2e-119 ARG A:153 A:153 146.0 0.649 -75.3 122.9