Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75758101 . G A CCDS7340.1:NM_003373.3:c.136Gcc>Acc_NP_003364.1:p.46A>T Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
 2020-09-30 ALA A:46 NA:NA DO NA DO DO DO NA NA NA
ALA C:46 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
 2021-01-27 ALA A:46 A:46 52.0 0.452 H -67.4 -47.6 52.0 0.452 0.0
7ktu 1 P18206 100.0 0.0 EM
 2021-01-27 ALA A:46 A:46 45.0 0.391 H -72.4 -32.5 45.0 0.391 0.0
7ktv 1 P18206 100.0 0.0 EM
 2021-01-27 ALA A:46 A:46 39.0 0.339 H -76.2 -27.5 39.0 0.339 0.0
7ktw 1 P18206 100.0 0.0 EM
 2021-01-27 ALA A:46 A:46 49.0 0.426 H -71.7 -38.5 49.0 0.426 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
 2005-11-15 ALA A:46 A:46 43.0 0.374 H -70.7 -51.8 43.0 0.374 0.0
ALA B:46 B:46 39.0 0.339 H -72.2 -52.4 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
 2018-03-14 ALA A:46 A:46 47.0 0.409 H -65.2 -46.4 47.0 0.409 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
 2020-01-29 ALA A:66 A:46 48.0 0.417 H -66.0 -30.9 48.0 0.417 0.0
1st6 1 P12003 86.42 0.0 X-RAY
 2004-08-03 ALA A:49 A:46 40.0 0.348 H -80.7 -31.5 40.0 0.348 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
 2006-08-08 ALA A:46 A:46 66.0 0.574 H -80.0 -28.0 51.0 0.443 0.131 B:P18010:0.13
3rf3 1 P18206 100.0 0.0 X-RAY
 2011-04-27 ALA A:46 A:46 63.0 0.548 H -65.9 -40.1 51.0 0.443 0.105 C:P18010:0.104
 HOH
 2.679
 HB3
 O
ALA B:46 B:46 63.0 0.548 H -66.3 -40.1 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
 2012-02-29 ALA A:46 A:46 65.0 0.565 H -63.3 -38.0 48.0 0.417 0.148 B:Q9Y490:0.148
 HOH
 2.664
 O
 O
2gww 1 P18206 100.0 0.0 X-RAY
 2006-11-14 ALA A:54 A:46 67.0 0.583 H -54.6 -46.5 48.0 0.417 0.166 B:32307018:0.165
 HOH
 5.058
 N
 O
2hsq 1 P18206 100.0 0.0 X-RAY
 2006-11-21 ALA A:54 A:46 60.0 0.522 H -84.1 -30.4 52.0 0.452 0.07 B:P18010:0.07
2ibf 1 P18206 100.0 0.0 X-RAY
 2007-09-18 ALA A:54 A:46 56.0 0.487 H -74.7 -55.9 38.0 0.33 0.157 B:P18010:0.157
1rkc 1 P18206 100.0 0.0 X-RAY
 2004-01-13 ALA A:50 A:46 64.0 0.557 S -82.0 -13.8 23.0 0.2 0.357 B:P54939:0.357
1rke 1 P18206 100.0 0.0 X-RAY
 2004-01-13 ALA A:50 A:46 43.0 0.374 H -61.2 -47.8 43.0 0.374 0.0 HOH
 2.293
 O
 O
1syq 1 P18206 100.0 0.0 X-RAY
 2004-07-20 ALA A:52 A:46 61.0 0.53 H -64.1 -47.4 49.0 0.426 0.104 B:Q9Y490:0.104
 HOH
 3.668
 CB
 O
1ydi 1 P18206-2 100.0 0.0 X-RAY
 2005-07-19 ALA A:51 A:46 64.0 0.557 H -67.0 -35.7 51.0 0.443 0.114 B:O43707:0.113
 HOH
 2.646
 O
 O
3tj6 1 P18206 100.0 0.0 X-RAY
 2011-09-07 ALA A:46 A:46 61.0 0.53 H -68.3 -42.4 49.0 0.426 0.104 B:B0BXR4:0.104
 HOH
 7.560
 CB
 O
1u6h 1 P12003 98.07 4e-180 X-RAY
 2005-01-18 ALA A:67 A:45 66.0 0.574 H -46.8 -53.7 54.0 0.47 0.104 B:Q8AWI0:0.104
 HOH
 2.818
 O
 O
1xwj 1 P12003 98.07 4e-180 X-RAY
 2005-10-11 ALA A:67 A:45 63.0 0.548 H -63.7 -39.2 34.0 0.296 0.252 B:Q8AWI0:0.252
 HOH
 7.823
 CB
 O
3zdl 1 P12003 98.07 4e-180 X-RAY
 2013-02-13 ALA A:67 A:45 62.0 0.539 H -59.4 -37.0 28.0 0.243 0.296 B:Q7Z5R6:0.296
 HOH
 2.767
 O
 O
6fq4 1 P12003 98.07 4e-180 X-RAY
 2018-05-09 ALA A:67 A:46 61.0 0.53 H -73.7 -60.0 31.0 0.27 0.26 B:None:0.261
1zvz 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ALA A:66 A:45 61.0 0.53 H -68.3 -37.8 47.0 0.409 0.121 B:P54939:0.122
 HOH
 2.692
 O
 O
1zw2 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ALA A:66 A:45 62.0 0.539 H -69.5 -39.9 51.0 0.443 0.096 B:45383127:0.096
 HOH
 3.502
 CB
 O
1zw3 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ALA A:66 A:45 61.0 0.53 H -35.3 -62.0 27.0 0.235 0.295 B:P26039:0.296
4e17 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 ALA A:50 A:46 59.0 0.513 H -67.9 -35.9 48.0 0.417 0.096 B:P26231:0.096
 HOH
 3.570
 CB
 O
4e18 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 ALA A:50 A:46 61.0 0.53 H -72.3 -36.8 49.0 0.426 0.104 B:P26231:0.104
 HOH
 3.582
 CB
 O
3tj5 1 P18206 100.0 9e-180 X-RAY
 2011-09-07 ALA A:46 A:46 64.0 0.557 H -68.9 -34.7 44.0 0.383 0.174 B:B0BXR4:0.174
 GOL
HOH
 7.102
2.741
 CB
O
 O1
O
3s90 1 P18206 100.0 6e-177 X-RAY
 2011-06-22 ALA A:47 A:46 63.0 0.548 H -64.3 -34.9 46.0 0.4 0.148 C:P26039:0.148
 HOH
 2.694
 O
 O
ALA B:47 B:46 66.0 0.574 H -64.2 -34.7 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
 2012-04-18 ALA A:47 A:46 63.0 0.548 H -67.1 -30.8 46.0 0.4 0.148 B:P35221:0.148
 HOH
 3.361
 CB
 O
1t01 1 P12003 98.03 3e-176 X-RAY
 2004-08-24 ALA A:47 A:46 61.0 0.53 H -61.6 -39.6 51.0 0.443 0.087 B:P26039:0.087
 HOH
 2.647
 O
 O
5y04 1 Q64727 100.0 3e-175 X-RAY
 2018-03-28 ALA A:48 A:46 59.0 0.513 H -48.2 -63.5 44.0 0.383 0.13 B:P26231:0.13

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 ALA A:46 A:46 48.0 0.417 H -64.2 -44.6