Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75830501 . C A CCDS7340.1:NM_003373.3:c.313Cga>Aga_NP_003364.1:p.105R>R Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
 2020-09-30 ARG A:105 NA:NA DO NA DO DO DO NA NA NA
ARG C:105 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:105 A:105 6.0 0.027 H -69.8 -25.3 6.0 0.027 0.0
7ktu 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:105 A:105 36.0 0.16 H -64.5 -34.8 36.0 0.16 0.0
7ktv 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:105 A:105 5.0 0.022 G -74.5 -1.0 5.0 0.022 0.0
7ktw 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:105 A:105 27.0 0.12 H -57.3 -53.7 27.0 0.12 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
 2005-11-15 ARG A:105 A:105 25.0 0.111 T -80.9 27.4 25.0 0.111 0.0 HOH
 5.839
 O
 O
ARG B:105 B:105 8.0 0.036 T -75.6 23.7 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
 2018-03-14 ARG A:105 A:105 27.0 0.12 H -76.8 -24.6 27.0 0.12 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
 2020-01-29 ARG A:125 A:105 54.0 0.24 H -76.7 -11.0 54.0 0.24 0.0
1st6 1 P12003 86.42 0.0 X-RAY
 2004-08-03 ARG A:108 A:105 49.0 0.218 H -75.0 -25.2 49.0 0.218 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
 2006-08-08 ARG A:105 A:105 113.0 0.502 H -49.5 -46.6 113.0 0.502 0.0 HOH
 6.180
 O
 O
3rf3 1 P18206 100.0 0.0 X-RAY
 2011-04-27 ARG A:105 A:105 15.0 0.067 H -58.3 -33.1 10.0 0.044 0.023 C:P18010:0.022
 HOH
 2.300
 HH21
 O
ARG B:105 B:105 14.0 0.062 H -66.4 -32.2 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
 2012-02-29 ARG A:105 A:105 21.0 NA H -66.3 -30.9 21.0 NA NA
2gww 1 P18206 100.0 0.0 X-RAY
 2006-11-14 ARG A:113 A:105 38.0 0.169 H -71.4 -31.4 34.0 0.151 0.018 B:32307018:0.018
 HOH
 5.993
 CB
 O
2hsq 1 P18206 100.0 0.0 X-RAY
 2006-11-21 ARG A:113 A:105 93.0 0.413 H -54.0 -40.7 71.0 0.316 0.097 B:P18010:0.098
2ibf 1 P18206 100.0 0.0 X-RAY
 2007-09-18 ARG A:113 A:105 3.0 0.013 H -72.1 -27.0 1.0 0.004 0.009 B:P18010:0.009
1rkc 1 P18206 100.0 0.0 X-RAY
 2004-01-13 ARG A:109 A:105 94.0 0.418 G -74.6 19.8 28.0 0.124 0.294 B:P54939:0.293
1rke 1 P18206 100.0 0.0 X-RAY
 2004-01-13 ARG A:109 A:105 27.0 0.12 H -66.0 -28.8 27.0 0.12 0.0 HOH
 2.888
 NH2
 O
1syq 1 P18206 100.0 0.0 X-RAY
 2004-07-20 ARG A:111 A:105 18.0 0.08 H -59.9 -36.2 18.0 0.08 0.0 HOH
 2.739
 CB
 O
1ydi 1 P18206-2 100.0 0.0 X-RAY
 2005-07-19 ARG A:110 A:105 59.0 0.262 H -60.8 -39.6 53.0 0.236 0.026 B:O43707:0.027
 HOH
 5.182
 O
 O
3tj6 1 P18206 100.0 0.0 X-RAY
 2011-09-07 ARG A:105 A:105 93.0 0.413 H -67.2 -49.6 68.0 0.302 0.111 B:B0BXR4:0.111
 HOH
 3.958
 NE
 O
1u6h 1 P12003 98.07 4e-180 X-RAY
 2005-01-18 ARG A:126 A:104 20.0 0.089 H -63.4 -43.4 20.0 0.089 0.0 HOH
 4.191
 CB
 O
1xwj 1 P12003 98.07 4e-180 X-RAY
 2005-10-11 ARG A:126 A:104 2.0 0.009 H -64.1 -41.2 2.0 0.009 0.0 HOH
 7.505
 C
 O
3zdl 1 P12003 98.07 4e-180 X-RAY
 2013-02-13 ARG A:126 A:104 6.0 0.027 H -61.0 -45.5 6.0 0.027 0.0 HOH
 4.100
 NH2
 O
6fq4 1 P12003 98.07 4e-180 X-RAY
 2018-05-09 ARG A:126 A:105 56.0 0.249 H -56.7 -53.4 56.0 0.249 0.0
1zvz 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ARG A:125 A:104 3.0 0.013 H -67.0 -40.1 3.0 0.013 0.0 HOH
 5.125
 O
 O
1zw2 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ARG A:125 A:104 17.0 0.076 H -70.5 -37.3 17.0 0.076 0.0 HOH
 2.837
 NH1
 O
1zw3 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ARG A:125 A:104 8.0 0.036 H -55.0 -42.1 8.0 0.036 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 ARG A:109 A:105 55.0 0.244 H -68.1 -42.7 27.0 0.12 0.124 B:P26231:0.124
 HOH
 5.570
 O
 O
4e18 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 ARG A:109 A:105 61.0 0.271 H -75.2 -35.5 41.0 0.182 0.089 B:P26231:0.089
 HOH
 6.113
 N
 O
3tj5 1 P18206 100.0 9e-180 X-RAY
 2011-09-07 ARG A:105 A:105 8.0 0.036 H -64.5 -41.0 8.0 0.036 0.0 HOH
 3.667
 NE
 O
3s90 1 P18206 100.0 6e-177 X-RAY
 2011-06-22 ARG A:106 A:105 1.0 0.004 H -68.3 -36.0 1.0 0.004 0.0 HOH
 3.250
 NH2
 O
ARG B:106 B:105 0.0 0.0 H -68.0 -36.9 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
 2012-04-18 ARG A:106 A:105 47.0 0.209 H -66.9 -23.8 37.0 0.164 0.045 B:P35221:0.044
 ACT
HOH
 2.619
2.751
 NH2
NH1
 O
O
1t01 1 P12003 98.03 3e-176 X-RAY
 2004-08-24 ARG A:106 A:105 4.0 0.018 H -63.8 -40.0 4.0 0.018 0.0 HOH
 3.543
 NE
 O
5y04 1 Q64727 100.0 3e-175 X-RAY
 2018-03-28 ARG A:107 A:105 22.0 NA H -61.8 -23.2 15.0 NA NA B:P26231:NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 ARG A:105 A:105 29.0 0.129 H -63.4 -40.2