Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75832578 . C A CCDS7340.1:NM_003373.3:c.590aCc>aAc_NP_003364.1:p.197T>N Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
 2020-09-30 THR A:197 NA:NA DO NA DO DO DO NA NA NA
THR C:197 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:197 A:197 31.0 0.221 H -70.5 -36.5 31.0 0.221 0.0
7ktu 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:197 A:197 47.0 0.336 H -68.3 -29.7 47.0 0.336 0.0
7ktv 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:197 A:197 23.0 0.164 H -66.9 -43.1 23.0 0.164 0.0
7ktw 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:197 A:197 48.0 0.343 H -69.0 -44.3 48.0 0.343 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
 2005-11-15 THR A:197 A:197 46.0 0.329 H -43.8 -58.8 46.0 0.329 0.0 HOH
 7.177
 OG1
 O
THR B:197 B:197 22.0 0.157 H -45.8 -60.6 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
 2018-03-14 THR A:197 A:197 34.0 0.243 H -63.5 -43.6 34.0 0.243 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
 2020-01-29 THR A:217 A:197 57.0 0.407 H -51.5 -47.7 57.0 0.407 0.0 HOH
 8.259
 CG2
 O
1st6 1 P12003 86.42 0.0 X-RAY
 2004-08-03 THR A:200 A:197 24.0 0.171 H -76.4 -28.9 24.0 0.171 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
 2006-08-08 THR A:197 A:197 41.0 0.293 H -47.6 -54.2 41.0 0.293 0.0 HOH
 7.320
 O
 O
3rf3 1 P18206 100.0 0.0 X-RAY
 2011-04-27 THR A:197 A:197 50.0 0.357 H -58.7 -46.5 50.0 0.357 0.0 CAC
HOH
 9.955
1.996
 N
HG1
 O1
O
THR B:197 B:197 49.0 0.35 H -59.6 -46.4 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
 2012-02-29 THR A:197 A:197 51.0 0.364 H -60.2 -47.1 51.0 0.364 0.0 HOH
 7.313
 O
 O
2gww 1 P18206 100.0 0.0 X-RAY
 2006-11-14 THR A:205 A:197 40.0 0.286 H -51.5 -41.5 40.0 0.286 0.0 HOH
 5.892
 C
 O
2hsq 1 P18206 100.0 0.0 X-RAY
 2006-11-21 THR A:205 A:197 39.0 0.279 H -51.5 -41.0 39.0 0.279 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
 2007-09-18 THR A:205 A:197 36.0 0.257 H -51.1 -49.5 36.0 0.257 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
 2004-01-13 THR A:201 A:197 50.0 0.357 H -69.7 -30.6 50.0 0.357 0.0
1rke 1 P18206 100.0 0.0 X-RAY
 2004-01-13 THR A:201 A:197 45.0 0.321 H -56.2 -44.2 45.0 0.321 0.0 HOH
 2.867
 OG1
 O
1syq 1 P18206 100.0 0.0 X-RAY
 2004-07-20 THR A:203 A:197 44.0 0.314 H -64.3 -39.6 44.0 0.314 0.0 HOH
 5.141
 N
 O
1ydi 1 P18206-2 100.0 0.0 X-RAY
 2005-07-19 THR A:202 A:197 52.0 0.371 H -60.1 -43.5 52.0 0.371 0.0 HOH
 2.551
 OG1
 O
3tj6 1 P18206 100.0 0.0 X-RAY
 2011-09-07 THR A:197 A:197 40.0 0.286 H -59.2 -45.9 40.0 0.286 0.0 HOH
 4.813
 OG1
 O
1u6h 1 P12003 98.07 4e-180 X-RAY
 2005-01-18 THR A:218 A:196 39.0 0.279 H -52.4 -54.1 39.0 0.279 0.0 HOH
 3.466
 OG1
 O
1xwj 1 P12003 98.07 4e-180 X-RAY
 2005-10-11 THR A:218 A:196 42.0 0.3 H -60.0 -36.4 42.0 0.3 0.0 HOH
 3.426
 O
 O
3zdl 1 P12003 98.07 4e-180 X-RAY
 2013-02-13 THR A:218 A:196 39.0 0.279 H -61.6 -41.5 39.0 0.279 0.0 HOH
 7.263
 OG1
 O
6fq4 1 P12003 98.07 4e-180 X-RAY
 2018-05-09 THR A:218 A:197 46.0 0.329 H -52.7 -45.3 46.0 0.329 0.0
1zvz 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 THR A:217 A:196 30.0 0.214 H -64.8 -43.7 30.0 0.214 0.0 HOH
 2.975
 OG1
 O
1zw2 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 THR A:217 A:196 36.0 0.257 H -65.1 -39.3 36.0 0.257 0.0 HOH
 3.530
 CG2
 O
1zw3 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 THR A:217 A:196 40.0 0.286 H -38.4 -7.3 40.0 0.286 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 THR A:201 A:197 34.0 0.243 H -66.8 -40.8 34.0 0.243 0.0
4e18 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 THR A:201 A:197 28.0 0.2 H -62.2 -42.8 28.0 0.2 0.0 HOH
 3.823
 OG1
 O
3tj5 1 P18206 100.0 9e-180 X-RAY
 2011-09-07 THR A:197 A:197 36.0 0.257 H -59.9 -42.9 36.0 0.257 0.0 HOH
 3.025
 OG1
 O
3s90 1 P18206 100.0 6e-177 X-RAY
 2011-06-22 THR A:198 A:197 53.0 0.379 H -66.3 -48.3 53.0 0.379 0.0 HOH
 2.539
 OG1
 O
THR B:198 B:197 55.0 0.393 H -65.9 -49.1 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
 2012-04-18 THR A:198 A:197 32.0 0.229 H -57.8 -50.3 32.0 0.229 0.0 ACT
HOH
 8.655
6.206
 CG2
N
 OXT
O
1t01 1 P12003 98.03 3e-176 X-RAY
 2004-08-24 THR A:198 A:197 31.0 0.221 H -66.1 -47.6 31.0 0.221 0.0 HOH
 2.972
 OG1
 O
5y04 1 Q64727 100.0 3e-175 X-RAY
 2018-03-28 THR A:199 A:197 46.0 0.329 H -64.2 -39.8 46.0 0.329 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 THR A:197 A:197 40.0 0.286 H -58.3 -44.1