Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75834503 . A C CCDS7340.1:NM_003373.3:c.625Atg>Ctg_NP_003364.1:p.209M>L Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
2020-09-30 MET A:209 NA:NA DO NA DO DO DO NA NA NA
MET C:209 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
2021-01-27 MET A:209 A:209 21.0 0.114 H -73.9 -38.9 21.0 0.114 0.0
7ktu 1 P18206 100.0 0.0 EM
2021-01-27 MET A:209 A:209 20.0 0.108 H -77.3 -31.1 20.0 0.108 0.0
7ktv 1 P18206 100.0 0.0 EM
2021-01-27 MET A:209 A:209 25.0 0.135 H -67.8 -43.0 25.0 0.135 0.0
7ktw 1 P18206 100.0 0.0 EM
2021-01-27 MET A:209 A:209 3.0 0.016 H -66.4 -39.5 3.0 0.016 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
2005-11-15 MSE A:209 A:209 0.0 0.0 H -44.8 -38.0 0.0 0.0 0.0 HOH
9.735
CE
O
MSE B:209 B:209 0.0 0.0 H -49.6 -42.2 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
2018-03-14 MET A:209 A:209 5.0 0.027 H -65.1 -32.4 5.0 0.027 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
2020-01-29 MET A:229 A:209 2.0 0.011 H -78.3 -33.9 2.0 0.011 0.0
1st6 1 P12003 86.42 0.0 X-RAY
2004-08-03 MET A:212 A:209 16.0 0.086 H -89.8 -14.1 16.0 0.086 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
2006-08-08 MET A:209 A:209 2.0 0.011 H -68.5 -50.7 2.0 0.011 0.0
3rf3 1 P18206 100.0 0.0 X-RAY
2011-04-27 MET A:209 A:209 2.0 0.011 H -68.2 -39.2 2.0 0.011 0.0 HOH
3.033
HE3
O
MET B:209 B:209 1.0 0.005 H -68.6 -39.6 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
2012-02-29 MET A:209 A:209 3.0 0.016 H -73.3 -29.5 3.0 0.016 0.0 HOH
4.032
CG
O
2gww 1 P18206 100.0 0.0 X-RAY
2006-11-14 MET A:217 A:209 1.0 0.005 H -62.4 -45.2 1.0 0.005 0.0 HOH
7.209
SD
O
2hsq 1 P18206 100.0 0.0 X-RAY
2006-11-21 MET A:217 A:209 6.0 0.032 H -74.1 -43.3 6.0 0.032 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
2007-09-18 MET A:217 A:209 2.0 0.011 H -76.7 -44.7 2.0 0.011 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
2004-01-13 MET A:213 A:209 1.0 0.005 H -74.4 -40.8 1.0 0.005 0.0
1rke 1 P18206 100.0 0.0 X-RAY
2004-01-13 MET A:213 A:209 3.0 0.016 H -75.3 -40.8 3.0 0.016 0.0 HOH
4.102
CG
O
1syq 1 P18206 100.0 0.0 X-RAY
2004-07-20 MET A:215 A:209 2.0 0.011 H -67.0 -39.1 2.0 0.011 0.0 HOH
3.496
CG
O
1ydi 1 P18206-2 100.0 0.0 X-RAY
2005-07-19 MET A:214 A:209 1.0 0.005 H -67.7 -37.7 1.0 0.005 0.0 HOH
3.982
CE
O
3tj6 1 P18206 100.0 0.0 X-RAY
2011-09-07 MET A:209 A:209 3.0 0.016 H -63.9 -40.8 3.0 0.016 0.0 HOH
4.182
CG
O
1u6h 1 P12003 98.07 4e-180 X-RAY
2005-01-18 MET A:230 A:208 2.0 0.011 H -82.4 -40.2 2.0 0.011 0.0 HOH
4.492
N
O
1xwj 1 P12003 98.07 4e-180 X-RAY
2005-10-11 MET A:230 A:208 3.0 0.016 H -75.0 -44.8 3.0 0.016 0.0 HOH
4.927
N
O
3zdl 1 P12003 98.07 4e-180 X-RAY
2013-02-13 MET A:230 A:208 2.0 0.011 H -75.5 -37.2 2.0 0.011 0.0 HOH
4.348
CG
O
6fq4 1 P12003 98.07 4e-180 X-RAY
2018-05-09 MET A:230 A:209 16.0 0.086 H -76.3 -50.4 16.0 0.086 0.0 HOH
3.769
CE
O
1zvz 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:229 A:208 2.0 0.011 H -63.7 -37.9 2.0 0.011 0.0 HOH
3.830
CE
O
1zw2 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:229 A:208 1.0 0.005 H -77.1 -42.8 1.0 0.005 0.0 HOH
3.952
CE
O
1zw3 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:229 A:208 1.0 0.005 H -71.3 -51.6 1.0 0.005 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
2012-05-16 MET A:213 A:209 0.0 0.0 H -80.8 -16.8 0.0 0.0 0.0 HOH
3.955
CB
O
4e18 1 P12003 98.07 7e-180 X-RAY
2012-05-16 MET A:213 A:209 1.0 0.005 H -68.1 -28.1 1.0 0.005 0.0 HOH
7.957
N
O
3tj5 1 P18206 100.0 9e-180 X-RAY
2011-09-07 MET A:209 A:209 3.0 0.016 H -64.2 -37.8 3.0 0.016 0.0 HOH
6.049
N
O
3s90 1 P18206 100.0 6e-177 X-RAY
2011-06-22 MET A:210 A:209 1.0 0.005 H -66.9 -39.2 1.0 0.005 0.0 HOH
4.227
CG
O
MET B:210 B:209 2.0 0.011 H -65.4 -37.6 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
2012-04-18 MET A:210 A:209 3.0 0.016 H -73.3 -44.4 3.0 0.016 0.0 HOH
4.738
N
O
1t01 1 P12003 98.03 3e-176 X-RAY
2004-08-24 MET A:210 A:209 1.0 0.005 H -69.9 -35.9 1.0 0.005 0.0 HOH
3.952
CE
O
5y04 1 Q64727 100.0 3e-175 X-RAY
2018-03-28 MET A:211 A:209 13.0 0.07 H -82.7 -40.7 13.0 0.07 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 MET A:209 A:209 2.0 0.011 H -70.8 -40.5