Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75834522 . C A CCDS7340.1:NM_003373.3:c.644aCt>aAt_NP_003364.1:p.215T>N Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
 2020-09-30 THR A:215 NA:NA DO NA DO DO DO NA NA NA
THR C:215 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:215 A:215 11.0 0.079 H -75.0 -29.7 11.0 0.079 0.0
7ktu 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:215 A:215 8.0 0.057 G -84.2 1.4 8.0 0.057 0.0
7ktv 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:215 A:215 23.0 0.164 T -111.8 6.4 23.0 0.164 0.0
7ktw 1 P18206 100.0 0.0 EM
 2021-01-27 THR A:215 A:215 2.0 0.014 H -75.5 -21.0 2.0 0.014 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
 2005-11-15 THR A:215 A:215 2.0 0.014 H -89.2 -51.7 2.0 0.014 0.0
THR B:215 B:215 1.0 0.007 H -91.9 -53.8 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
 2018-03-14 THR A:215 A:215 12.0 0.086 H -65.3 -22.9 12.0 0.086 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
 2020-01-29 THR A:235 A:215 4.0 0.029 -92.3 69.2 4.0 0.029 0.0 HOH
 8.551
 CA
 O
1st6 1 P12003 86.42 0.0 X-RAY
 2004-08-03 THR A:218 A:215 10.0 0.071 H -89.4 -16.0 10.0 0.071 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
 2006-08-08 THR A:215 A:215 24.0 0.171 H -63.8 -36.4 24.0 0.171 0.0
3rf3 1 P18206 100.0 0.0 X-RAY
 2011-04-27 THR A:215 A:215 12.0 0.086 H -65.0 -39.9 12.0 0.086 0.0 HOH
 3.593
 HG22
 O
THR B:215 B:215 11.0 0.079 H -61.1 -41.5 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
 2012-02-29 THR A:215 A:215 83.0 0.593 -79.4 360.0 83.0 0.593 0.0 HOH
 9.134
 OG1
 O
2gww 1 P18206 100.0 0.0 X-RAY
 2006-11-14 THR A:223 A:215 25.0 0.179 H -63.8 -32.6 25.0 0.179 0.0 HOH
 8.362
 OG1
 O
2hsq 1 P18206 100.0 0.0 X-RAY
 2006-11-21 THR A:223 A:215 21.0 0.15 H -79.5 -39.6 21.0 0.15 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
 2007-09-18 THR A:223 A:215 29.0 0.207 H -55.5 -31.0 29.0 0.207 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
 2004-01-13 THR A:219 A:215 32.0 0.229 H -77.6 -6.4 32.0 0.229 0.0
1rke 1 P18206 100.0 0.0 X-RAY
 2004-01-13 THR A:219 A:215 29.0 0.207 H -65.1 -43.7 29.0 0.207 0.0 HOH
 3.048
 OG1
 O
1syq 1 P18206 100.0 0.0 X-RAY
 2004-07-20 THR A:221 A:215 24.0 0.171 H -57.7 -45.4 24.0 0.171 0.0 HOH
 4.506
 OG1
 O
1ydi 1 P18206-2 100.0 0.0 X-RAY
 2005-07-19 THR A:220 A:215 16.0 0.114 H -65.5 -45.0 16.0 0.114 0.0 HOH
 2.311
 OG1
 O
3tj6 1 P18206 100.0 0.0 X-RAY
 2011-09-07 THR A:215 A:215 29.0 0.207 H -80.9 -41.3 29.0 0.207 0.0 HOH
 5.589
 O
 O
1u6h 1 P12003 98.07 4e-180 X-RAY
 2005-01-18 THR A:236 A:214 20.0 0.143 H -88.0 -3.4 20.0 0.143 0.0 HOH
 3.972
 CA
 O
1xwj 1 P12003 98.07 4e-180 X-RAY
 2005-10-11 THR A:236 A:214 25.0 0.179 H -63.6 -24.6 25.0 0.179 0.0 HOH
 7.722
 OG1
 O
3zdl 1 P12003 98.07 4e-180 X-RAY
 2013-02-13 THR A:236 A:214 21.0 0.15 H -70.7 -28.9 21.0 0.15 0.0 HOH
 9.577
 OG1
 O
6fq4 1 P12003 98.07 4e-180 X-RAY
 2018-05-09 THR A:236 A:215 21.0 0.15 H -66.2 -34.8 21.0 0.15 0.0 HOH
 9.441
 OG1
 O
1zvz 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 THR A:235 A:214 33.0 0.236 H -127.4 12.6 33.0 0.236 0.0 HOH
 2.850
 OG1
 O
1zw2 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 THR A:235 A:214 31.0 0.221 H -60.6 -29.0 31.0 0.221 0.0 HOH
 3.501
 O
 O
1zw3 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 THR A:235 A:214 22.0 0.157 H -71.8 -30.4 22.0 0.157 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 THR A:219 A:215 61.0 0.436 H -67.7 -29.8 61.0 0.436 0.0
4e18 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 THR A:219 A:215 100.0 0.714 H -68.0 -41.7 100.0 0.714 0.0
3tj5 1 P18206 100.0 9e-180 X-RAY
 2011-09-07 THR A:215 A:215 28.0 0.2 H -106.6 2.9 28.0 0.2 0.0 HOH
 4.001
 C
 O
3s90 1 P18206 100.0 6e-177 X-RAY
 2011-06-22 THR A:216 A:215 17.0 0.121 H -62.8 -42.0 17.0 0.121 0.0 HOH
 3.363
 CG2
 O
THR B:216 B:215 17.0 0.121 S -128.7 12.4 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
 2012-04-18 THR A:216 A:215 39.0 0.279 H -76.8 -10.3 39.0 0.279 0.0 HOH
 7.210
 OG1
 O
1t01 1 P12003 98.03 3e-176 X-RAY
 2004-08-24 THR A:216 A:215 22.0 0.157 H -75.2 -46.2 22.0 0.157 0.0
5y04 1 Q64727 100.0 3e-175 X-RAY
 2018-03-28 THR A:217 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 THR A:215 A:215 1.0 0.007 H -70.1 -39.2