Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75834567 . G A CCDS7340.1:NM_003373.3:c.689cGc>cAc_NP_003364.1:p.230R>H Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
 2020-09-30 ARG A:230 NA:NA DO NA DO DO DO NA NA NA
ARG C:230 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:230 A:230 7.0 0.031 H -59.4 -50.6 7.0 0.031 0.0
7ktu 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:230 A:230 29.0 0.129 H -69.3 -41.8 29.0 0.129 0.0
7ktv 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:230 A:230 5.0 0.022 H -67.8 -31.4 5.0 0.022 0.0
7ktw 1 P18206 100.0 0.0 EM
 2021-01-27 ARG A:230 A:230 10.0 0.044 H -73.7 -63.0 10.0 0.044 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
 2005-11-15 ARG A:230 A:230 5.0 0.022 H -47.7 -43.4 5.0 0.022 0.0
ARG B:230 B:230 4.0 0.018 H -48.4 -42.3 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
 2018-03-14 ARG A:230 A:230 13.0 0.058 H -66.9 -49.3 13.0 0.058 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
 2020-01-29 ARG A:250 A:230 1.0 0.004 H -82.6 -30.5 1.0 0.004 0.0
1st6 1 P12003 86.42 0.0 X-RAY
 2004-08-03 ARG A:233 A:230 6.0 0.027 H -71.3 -33.6 6.0 0.027 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
 2006-08-08 ARG A:230 A:230 8.0 0.036 H -56.4 -51.3 8.0 0.036 0.0 HOH
 6.033
 NH2
 O
3rf3 1 P18206 100.0 0.0 X-RAY
 2011-04-27 ARG A:230 A:230 4.0 0.018 H -66.8 -47.9 4.0 0.018 0.0 HOH
 1.989
 HE
 O
ARG B:230 B:230 5.0 0.022 H -66.5 -48.0 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
 2012-02-29 ARG A:230 A:230 3.0 0.013 H -69.3 -46.3 3.0 0.013 0.0 HOH
 2.852
 NH1
 O
2gww 1 P18206 100.0 0.0 X-RAY
 2006-11-14 ARG A:238 A:230 11.0 0.049 H -60.3 -47.9 11.0 0.049 0.0 HOH
 4.233
 NH2
 O
2hsq 1 P18206 100.0 0.0 X-RAY
 2006-11-21 ARG A:238 A:230 9.0 0.04 H -65.3 -77.9 9.0 0.04 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
 2007-09-18 ARG A:238 A:230 9.0 0.04 H -75.0 -43.3 9.0 0.04 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
 2004-01-13 ARG A:234 A:230 10.0 0.044 H -50.2 -53.0 10.0 0.044 0.0
1rke 1 P18206 100.0 0.0 X-RAY
 2004-01-13 ARG A:234 A:230 9.0 0.04 H -70.3 -49.2 9.0 0.04 0.0 HOH
 2.758
 NH1
 O
1syq 1 P18206 100.0 0.0 X-RAY
 2004-07-20 ARG A:236 A:230 6.0 0.027 H -67.4 -44.6 6.0 0.027 0.0 HOH
 2.758
 NH1
 O
1ydi 1 P18206-2 100.0 0.0 X-RAY
 2005-07-19 ARG A:235 A:230 8.0 0.036 H -63.8 -50.3 8.0 0.036 0.0 HOH
 2.902
 NE
 O
3tj6 1 P18206 100.0 0.0 X-RAY
 2011-09-07 ARG A:230 A:230 6.0 0.027 H -64.5 -52.7 6.0 0.027 0.0 HOH
 2.870
 NH1
 O
1u6h 1 P12003 98.07 4e-180 X-RAY
 2005-01-18 ARG A:251 A:229 4.0 0.018 H -64.6 -46.0 4.0 0.018 0.0 HOH
 2.336
 NH1
 O
1xwj 1 P12003 98.07 4e-180 X-RAY
 2005-10-11 ARG A:251 A:229 4.0 0.018 H -64.7 -43.4 4.0 0.018 0.0 HOH
 4.129
 N
 O
3zdl 1 P12003 98.07 4e-180 X-RAY
 2013-02-13 ARG A:251 A:229 4.0 0.018 H -64.2 -45.1 4.0 0.018 0.0 HOH
 2.558
 NH2
 O
6fq4 1 P12003 98.07 4e-180 X-RAY
 2018-05-09 ARG A:251 A:230 6.0 0.027 H -69.9 -64.3 6.0 0.027 0.0 HOH
 2.917
 NH1
 O
1zvz 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ARG A:250 A:229 15.0 0.067 H -61.8 -52.2 15.0 0.067 0.0 HOH
 3.088
 NH2
 O
1zw2 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ARG A:250 A:229 5.0 0.022 H -62.9 -45.1 5.0 0.022 0.0 HOH
 2.712
 NH2
 O
1zw3 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 ARG A:250 A:229 6.0 0.027 H -77.8 -59.3 6.0 0.027 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 ARG A:234 A:230 9.0 0.04 H -66.4 -53.2 9.0 0.04 0.0 HOH
 3.256
 CD
 O
4e18 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 ARG A:234 A:230 9.0 0.04 H -65.5 -54.3 9.0 0.04 0.0 HOH
 9.529
 O
 O
3tj5 1 P18206 100.0 9e-180 X-RAY
 2011-09-07 ARG A:230 A:230 8.0 0.036 H -64.3 -55.1 8.0 0.036 0.0 HOH
 2.775
 NE
 O
3s90 1 P18206 100.0 6e-177 X-RAY
 2011-06-22 ARG A:231 A:230 5.0 0.022 H -65.2 -46.9 5.0 0.022 0.0 HOH
 2.776
 NH2
 O
ARG B:231 B:230 12.0 0.053 H -64.7 -53.6 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
 2012-04-18 ARG A:231 A:230 4.0 0.018 H -65.2 -41.9 4.0 0.018 0.0 ACT
HOH
 6.081
3.678
 N
N
 O
O
1t01 1 P12003 98.03 3e-176 X-RAY
 2004-08-24 ARG A:231 A:230 8.0 0.036 H -66.1 -48.9 8.0 0.036 0.0 HOH
 2.728
 NH1
 O
5y04 1 Q64727 100.0 3e-175 X-RAY
 2018-03-28 ARG A:232 A:230 10.0 0.044 H -84.7 -57.2 10.0 0.044 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 ARG A:230 A:230 11.0 0.049 H -59.8 -53.6