Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75834592 . T A CCDS7340.1:NM_003373.3:c.714agT>agA_NP_003364.1:p.238S>R Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
 2020-09-30 SER A:238 NA:NA DO NA DO DO DO NA NA NA
SER C:238 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
 2021-01-27 SER A:238 A:238 33.0 0.287 H -66.9 -28.0 33.0 0.287 0.0
7ktu 1 P18206 100.0 0.0 EM
 2021-01-27 SER A:238 A:238 17.0 0.148 H -70.4 -23.0 17.0 0.148 0.0
7ktv 1 P18206 100.0 0.0 EM
 2021-01-27 SER A:238 A:238 28.0 0.243 H -69.0 -22.8 28.0 0.243 0.0
7ktw 1 P18206 100.0 0.0 EM
 2021-01-27 SER A:238 A:238 5.0 0.043 H -69.0 -20.1 5.0 0.043 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
 2005-11-15 SER A:238 A:238 20.0 0.174 H -72.9 -17.0 20.0 0.174 0.0 HOH
 5.655
 O
 O
SER B:238 B:238 21.0 0.183 H -64.6 -14.0 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
 2018-03-14 SER A:238 A:238 22.0 0.191 H -60.0 -39.0 22.0 0.191 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
 2020-01-29 SER A:258 A:238 24.0 0.209 H -64.3 -35.7 24.0 0.209 0.0 HOH
 5.256
 O
 O
1st6 1 P12003 86.42 0.0 X-RAY
 2004-08-03 SER A:241 A:238 31.0 0.27 H -69.1 -21.0 31.0 0.27 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
 2006-08-08 SER A:238 A:238 24.0 0.209 H -66.3 -44.7 24.0 0.209 0.0 HOH
 7.465
 OG
 O
3rf3 1 P18206 100.0 0.0 X-RAY
 2011-04-27 SER A:238 A:238 24.0 0.209 H -64.7 -40.1 24.0 0.209 0.0 HOH
 2.770
 OG
 O
SER B:238 B:238 25.0 0.217 H -65.5 -39.3 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
 2012-02-29 SER A:238 A:238 20.0 0.174 H -61.8 -39.5 20.0 0.174 0.0 HOH
 2.684
 OG
 O
2gww 1 P18206 100.0 0.0 X-RAY
 2006-11-14 SER A:246 A:238 22.0 0.191 H -57.7 -40.4 22.0 0.191 0.0 HOH
 3.936
 CB
 O
2hsq 1 P18206 100.0 0.0 X-RAY
 2006-11-21 SER A:246 A:238 21.0 0.183 H -58.8 -39.5 21.0 0.183 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
 2007-09-18 SER A:246 A:238 21.0 0.183 H -60.4 -37.8 21.0 0.183 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
 2004-01-13 SER A:242 A:238 25.0 0.217 H -75.9 -46.2 25.0 0.217 0.0
1rke 1 P18206 100.0 0.0 X-RAY
 2004-01-13 SER A:242 A:238 25.0 0.217 H -56.1 -40.6 25.0 0.217 0.0 HOH
 2.730
 OG
 O
1syq 1 P18206 100.0 0.0 X-RAY
 2004-07-20 SER A:244 A:238 21.0 0.183 H -63.2 -37.4 21.0 0.183 0.0 HOH
 2.776
 OG
 O
1ydi 1 P18206-2 100.0 0.0 X-RAY
 2005-07-19 SER A:243 A:238 25.0 0.217 H -66.7 -36.6 25.0 0.217 0.0 HOH
 2.783
 OG
 O
3tj6 1 P18206 100.0 0.0 X-RAY
 2011-09-07 SER A:238 A:238 22.0 0.191 H -64.1 -42.2 22.0 0.191 0.0 HOH
 2.689
 OG
 O
1u6h 1 P12003 98.07 4e-180 X-RAY
 2005-01-18 SER A:259 A:237 27.0 0.235 H -50.6 -58.3 27.0 0.235 0.0 HOH
 4.893
 O
 O
1xwj 1 P12003 98.07 4e-180 X-RAY
 2005-10-11 SER A:259 A:237 26.0 0.226 H -65.8 -50.0 26.0 0.226 0.0 HOH
 2.839
 OG
 O
3zdl 1 P12003 98.07 4e-180 X-RAY
 2013-02-13 SER A:259 A:237 22.0 0.191 H -66.1 -39.6 22.0 0.191 0.0 HOH
 2.909
 OG
 O
6fq4 1 P12003 98.07 4e-180 X-RAY
 2018-05-09 SER A:259 A:238 23.0 0.2 H -61.6 -47.0 23.0 0.2 0.0
1zvz 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 SER A:258 A:237 22.0 0.191 H -61.7 -40.5 22.0 0.191 0.0 HOH
 2.816
 OG
 O
1zw2 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 SER A:258 A:237 22.0 0.191 H -64.0 -33.7 22.0 0.191 0.0 HOH
 3.462
 O
 O
1zw3 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 SER A:258 A:237 21.0 0.183 H -45.9 -58.7 21.0 0.183 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 SER A:242 A:238 22.0 0.191 H -64.2 -40.8 22.0 0.191 0.0 HOH
 2.778
 OG
 O
4e18 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 SER A:242 A:238 24.0 0.209 H -63.1 -43.1 24.0 0.209 0.0 HOH
 2.756
 OG
 O
3tj5 1 P18206 100.0 9e-180 X-RAY
 2011-09-07 SER A:238 A:238 23.0 0.2 H -66.3 -40.8 23.0 0.2 0.0 HOH
 2.641
 OG
 O
3s90 1 P18206 100.0 6e-177 X-RAY
 2011-06-22 SER A:239 A:238 22.0 0.191 H -64.0 -41.9 22.0 0.191 0.0 HOH
 2.756
 OG
 O
SER B:239 B:238 21.0 0.183 H -64.2 -42.3 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
 2012-04-18 SER A:239 A:238 21.0 0.183 H -68.9 -37.0 21.0 0.183 0.0 HOH
 3.002
 OG
 O
1t01 1 P12003 98.03 3e-176 X-RAY
 2004-08-24 SER A:239 A:238 23.0 0.2 H -58.3 -39.0 23.0 0.2 0.0 HOH
 2.822
 OG
 O
5y04 1 Q64727 100.0 3e-175 X-RAY
 2018-03-28 SER A:240 A:238 27.0 0.235 H -69.1 -37.0 27.0 0.235 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 SER A:238 A:238 24.0 0.209 H -65.8 -39.5