Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 101163517 . A C CCDS7479.1:NM_002079.2:c.757Tgt>Ggt_NP_002070.1:p.253C>G Homo sapiens glutamic-oxaloacetic transaminase 1 (GOT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wzf 1 P17174 100.0 0.0 X-RAY
 2015-10-07 CYS A:252 A:252 0.0 0.0 E -111.6 123.2 0.0 0.0 0.0
6dnd 1 P17174 100.0 0.0 X-RAY
 2018-11-14 CYS A:251 A:253 0.0 0.0 E -139.0 111.4 0.0 0.0 0.0 PLP
HOH
 9.683
5.585
 C
SG
 C6
O
CYS B:251 B:253 0.0 0.0 E -139.9 109.0 NA NA NA
6lig 1 P17174 100.0 0.0 X-RAY
 2020-12-16 CYS A:251 A:253 0.0 0.0 E -145.8 101.2 0.0 0.0 0.0 EE6
HOH
 9.340
6.357
 C
SG
 C25
O
CYS B:251 B:253 1.0 0.007 E -141.8 111.2 1.0 0.007 0.0 PLP
HOH
 9.808
5.659
 C
SG
 N1
O
6dnb 1 P17174 99.27 0.0 X-RAY
 2018-11-14 CYS A:251 A:253 0.0 0.0 E -145.1 108.7 0.0 0.0 0.0 HOH
 5.520
 SG
 O
6dna 1 P17174 99.75 0.0 X-RAY
 2018-11-14 CYS A:248 A:253 0.0 0.0 E -151.6 113.6 0.0 0.0 0.0 PLP
 9.812
 C
 N1
CYS B:248 B:253 0.0 0.0 E -149.3 110.1 NA NA NA
CYS C:248 C:253 0.0 0.0 E -148.7 107.8 NA NA NA
CYS D:248 D:253 0.0 0.0 E -151.2 109.6 NA NA NA
CYS E:248 E:253 1.0 0.007 E -150.3 107.5 NA NA NA
CYS F:248 F:253 0.0 0.0 E -149.5 110.4 NA NA NA
3ii0 1 P17174 100.0 0.0 X-RAY
 2009-08-11 CYS A:241 A:253 0.0 0.0 E -143.5 107.0 0.0 0.0 0.0 PLP
EDO
HOH
 9.885
9.904
5.522
 C
O
SG
 N1
O2
O
CYS B:241 B:253 0.0 0.0 E -141.9 104.6 NA NA NA
CYS C:241 C:253 1.0 0.007 E -144.6 106.1 NA NA NA
CYS D:241 D:253 0.0 0.0 E -139.6 115.9 NA NA NA
5toq 1 P00503 92.01 0.0 X-RAY
 2017-03-01 CYS A:254 A:252 0.0 0.0 E -139.6 108.2 0.0 0.0 0.0 HOH
 5.474
 SG
 O
CYS B:254 B:252 0.0 0.0 E -139.3 109.7 0.0 0.0 0.0 HOH
 3.737
 SG
 O
5vk7 1 P00503 92.01 0.0 X-RAY
 2017-11-01 CYS A:254 A:252 0.0 0.0 E -138.0 110.8 0.0 0.0 0.0 HOH
 5.505
 SG
 O
CYS B:254 B:252 1.0 0.007 E -134.8 109.8 1.0 0.007 0.0 HOH
 5.577
 SG
 O
1ajr 1 P00503 91.99 0.0 X-RAY
 1997-08-20 CYS A:252 A:252 0.0 0.0 E -134.1 112.5 0.0 0.0 0.0 HOH
 5.570
 SG
 O
CYS B:252 B:252 0.0 0.0 E -139.6 108.4 0.0 0.0 0.0 HOH
 5.572
 SG
 O
1ajs 1 P00503 91.99 0.0 X-RAY
 1997-08-20 CYS A:252 A:252 0.0 0.0 E -135.3 110.1 0.0 0.0 0.0 HOH
 5.495
 SG
 O
1ajs 2 P00503 91.99 0.0 X-RAY
 1997-08-20 CYS B:252 B:252 0.0 0.0 E -138.7 107.4 0.0 0.0 0.0 HOH
 5.671
 SG
 O
5vjz 1 P00503 91.99 0.0 NEUTRON DIFFRACTION
X-RAY
 2017-11-01 CYS A:252 A:252 0.0 0.0 E -139.6 107.8 0.0 0.0 0.0 PLA
 9.260
 HG
 D1Z
5vjz 2 P00503 91.99 0.0 NEUTRON DIFFRACTION
X-RAY
 2017-11-01 CYS B:252 B:252 0.0 0.0 E -140.8 109.8 NA NA NA
5tor 1 P00503 91.77 0.0 X-RAY
 2017-03-01 CYS A:254 A:252 0.0 0.0 E -137.7 111.4 0.0 0.0 0.0 HOH
 5.598
 SG
 O
CYS B:254 B:252 0.0 0.0 E -138.8 112.7 0.0 0.0 0.0 HOH
 5.455
 SG
 O
5ton 1 P00503 91.77 0.0 X-RAY
 2017-03-01 CYS A:254 A:252 0.0 0.0 E -138.2 111.6 0.0 0.0 0.0 HOH
 5.513
 SG
 O
CYS B:254 B:252 0.0 0.0 E -138.8 111.4 0.0 0.0 0.0 HOH
 5.416
 SG
 O
5tot 1 P00503 91.53 0.0 X-RAY
 2017-03-01 CYS A:254 A:252 0.0 0.0 E -138.9 110.0 0.0 0.0 0.0 HOH
 5.476
 SG
 O
CYS B:254 B:252 0.0 0.0 E -137.9 112.0 0.0 0.0 0.0 HOH
 5.387
 SG
 O
2cst 1 P00504 80.44 0.0 X-RAY
 1994-11-30 CYS A:251 A:252 0.0 0.0 E -137.5 111.8 0.0 0.0 0.0 HOH
 4.167
 SG
 O
CYS B:251 B:252 1.0 0.007 E -129.0 111.5 1.0 0.007 0.0 HOH
 4.235
 SG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17174-f1 1 P17174 100.0 0.0 CYS A:253 A:253 0.0 0.0 E -133.3 108.6