Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 103339293 | . | G | A | CCDS7513.1:NM_001174084.1:c.1645Cga>Tga_NP_001167555.1:p.549R>* | Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xq8 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:308 | B:549 | 156.0 | 0.693 | E | -97.6 | 143.3 | 156.0 | 0.693 | 0.0 | ||||||
| ARG | B:308 | A:549 | 135.0 | 0.6 | -105.0 | 124.0 | NA | NA | NA | ||||||||||||||
| 5ca7 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:308 | B:549 | 157.0 | 0.698 | E | -124.4 | 138.9 | 157.0 | 0.698 | 0.0 |
HOH |
5.020 |
C |
O |
||
| ARG | B:308 | A:549 | 138.0 | 0.613 | -102.6 | 123.1 | NA | NA | NA | ||||||||||||||
| 5iii | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:308 | A:549 | 166.0 | 0.738 | -107.5 | 125.4 | 166.0 | 0.738 | 0.0 |
HOH |
3.223 |
NH1 |
O |
|||
| 5iij | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:308 | A:549 | 170.0 | 0.756 | -118.3 | 122.5 | 170.0 | 0.756 | 0.0 |
HOH |
3.640 |
CG |
O |
|||
| 5iik | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:308 | A:549 | 158.0 | 0.702 | E | -126.1 | 141.6 | 158.0 | 0.702 | 0.0 |
HOH |
2.885 |
NH1 |
O |
||
| 5iil | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:308 | A:549 | 156.0 | 0.693 | E | -127.2 | 126.0 | 156.0 | 0.693 | 0.0 |
HOH |
3.002 |
NE |
O |
||
| 5iim | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-09-07 | ARG | A:308 | A:549 | 163.0 | 0.724 | E | -132.4 | 147.5 | 163.0 | 0.724 | 0.0 |
HOH |
3.001 |
NH1 |
O |
||
| 5iin | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:308 | A:549 | 154.0 | 0.684 | E | -105.5 | 134.3 | 154.0 | 0.684 | 0.0 |
HOH |
2.967 |
NH1 |
O |
||
| 5iio | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | M:308 | A:549 | 202.0 | 0.898 | -100.7 | 138.2 | 202.0 | 0.898 | 0.0 |
HOH |
2.919 |
NH2 |
O |
|||
| ARG | N:308 | E:549 | 202.0 | 0.898 | -87.5 | 136.6 | NA | NA | NA | ||||||||||||||
| ARG | O:308 | I:549 | 201.0 | 0.893 | -111.1 | 146.6 | NA | NA | NA | ||||||||||||||
| ARG | P:308 | M:549 | 196.0 | 0.871 | -115.0 | 138.7 | NA | NA | NA | ||||||||||||||
| 1xsl | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2005-01-18 | ARG | M:309 | A:549 | 194.0 | 0.862 | -92.2 | 131.9 | 194.0 | 0.862 | 0.0 |
HOH |
2.696 |
NE |
O |
|||
| ARG | N:309 | E:549 | 194.0 | 0.862 | -104.2 | 125.2 | NA | NA | NA | ||||||||||||||
| ARG | O:309 | I:549 | 207.0 | 0.92 | -88.6 | 139.3 | NA | NA | NA | ||||||||||||||
| ARG | P:309 | M:549 | 188.0 | 0.836 | -86.5 | 141.1 | NA | NA | NA | ||||||||||||||
| 2bcq | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:309 | A:549 | 157.0 | 0.698 | E | -123.4 | 131.7 | 157.0 | 0.698 | 0.0 |
DT HOH |
8.701 2.940 |
N NH1 |
C7 O |
||
| 2bcr | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:309 | A:549 | 158.0 | 0.702 | E | -118.5 | 125.9 | 158.0 | 0.702 | 0.0 |
DA HOH |
8.921 2.944 |
N NH2 |
N6 O |
||
| 2bcs | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:309 | A:549 | 156.0 | 0.693 | E | -117.8 | 134.0 | 156.0 | 0.693 | 0.0 |
DC HOH |
9.275 2.944 |
N NH1 |
N4 O |
||
| 2bcu | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:309 | A:549 | 155.0 | 0.689 | E | -131.6 | 142.4 | 155.0 | 0.689 | 0.0 |
HOH |
2.683 |
NH2 |
O |
||
| 2bcv | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:309 | A:549 | 154.0 | 0.684 | E | -121.2 | 134.0 | 154.0 | 0.684 | 0.0 |
DT HOH |
9.223 2.667 |
N NH2 |
O4 O |
||
| 2gws | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-09-05 | ARG | M:309 | A:549 | 194.0 | 0.862 | -96.1 | 135.7 | 194.0 | 0.862 | 0.0 |
HOH |
2.446 |
NH2 |
O |
|||
| ARG | N:309 | E:549 | 189.0 | 0.84 | -106.4 | 127.1 | NA | NA | NA | ||||||||||||||
| ARG | O:309 | I:549 | 197.0 | 0.876 | -104.6 | 134.7 | NA | NA | NA | ||||||||||||||
| ARG | P:309 | M:549 | 57.0 | NA | -100.5 | 125.4 | NA | NA | NA | ||||||||||||||
| 4xrh | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:309 | B:549 | 159.0 | 0.707 | E | -107.9 | 137.0 | 159.0 | 0.707 | 0.0 | ||||||
| ARG | B:309 | A:549 | 135.0 | 0.6 | -110.9 | 123.5 | NA | NA | NA | ||||||||||||||
| 5ddm | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:309 | B:549 | 155.0 | 0.689 | E | -99.9 | 135.2 | 155.0 | 0.689 | 0.0 |
HOH |
7.772 |
O |
O |
||
| ARG | B:309 | A:549 | 134.0 | 0.596 | -107.2 | 121.0 | NA | NA | NA | ||||||||||||||
| 5ddy | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:309 | A:549 | 155.0 | 0.689 | -103.2 | 159.6 | 155.0 | 0.689 | 0.0 | |||||||
| ARG | B:309 | C:549 | 156.0 | 0.693 | -113.3 | 152.5 | NA | NA | NA | ||||||||||||||
| ARG | C:309 | E:549 | 161.0 | 0.716 | -69.8 | 147.9 | NA | NA | NA | ||||||||||||||
| ARG | D:309 | G:549 | 126.0 | 0.56 | -72.5 | 153.2 | NA | NA | NA | ||||||||||||||
| 3c5g | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2008-07-29 | ARG | A:309 | A:549 | 203.0 | 0.902 | -82.0 | 137.9 | 203.0 | 0.902 | 0.0 |
DT HOH |
9.963 2.795 |
N NH1 |
OP1 O |
|||
| ARG | E:309 | B:549 | 204.0 | 0.907 | -83.8 | 131.5 | NA | NA | NA | ||||||||||||||
| 5chg | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:308 | A:549 | 157.0 | 0.698 | E | -134.2 | 145.6 | 157.0 | 0.698 | 0.0 | ||||||
| ARG | B:308 | B:549 | 140.0 | 0.622 | -124.9 | 149.8 | NA | NA | NA | ||||||||||||||
| 5cj7 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:308 | A:549 | 161.0 | 0.716 | -113.4 | 117.9 | 161.0 | 0.716 | 0.0 | |||||||
| ARG | B:308 | B:549 | 141.0 | 0.627 | -121.3 | 144.6 | NA | NA | NA | ||||||||||||||
| 5cp2 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:308 | A:549 | 130.0 | 0.578 | -110.5 | 127.4 | 130.0 | 0.578 | 0.0 |
HOH |
2.908 |
NH2 |
O |
|||
| ARG | B:308 | B:549 | 148.0 | 0.658 | E | -134.5 | 119.7 | NA | NA | NA | |||||||||||||
| 5cr0 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:308 | A:549 | 156.0 | 0.693 | E | -109.3 | 144.2 | 156.0 | 0.693 | 0.0 | ||||||
| ARG | B:308 | B:549 | 141.0 | 0.627 | -108.1 | 144.6 | NA | NA | NA | ||||||||||||||
| 3c5f | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2008-09-02 | ARG | G:309 | A:549 | 204.0 | 0.907 | -91.9 | 128.9 | 204.0 | 0.907 | 0.0 |
DT NA HOH |
9.916 9.128 3.209 |
N C NH1 |
OP1 NA O |
|||
| ARG | H:309 | B:549 | 206.0 | 0.916 | -81.2 | 128.1 | NA | NA | NA | ||||||||||||||
| 1xsn | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2005-01-18 | ARG | D:309 | A:549 | 152.0 | 0.676 | E | -114.0 | 139.3 | 152.0 | 0.676 | 0.0 |
HOH |
2.871 |
NH1 |
O |
||
| 1xsp | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2005-01-18 | ARG | D:309 | A:549 | 156.0 | 0.693 | E | -135.1 | 146.9 | 156.0 | 0.693 | 0.0 |
HOH |
2.644 |
NH2 |
O |
||
| 2pfn | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:309 | A:549 | 150.0 | 0.667 | E | -131.9 | 129.5 | 150.0 | 0.667 | 0.0 |
HOH |
2.782 |
NH1 |
O |
||
| 2pfo | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:309 | A:549 | 152.0 | 0.676 | E | -102.3 | 144.5 | 152.0 | 0.676 | 0.0 |
HOH |
3.909 |
C |
O |
||
| 2pfp | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:309 | A:549 | 159.0 | 0.707 | E | -132.2 | 151.1 | 159.0 | 0.707 | 0.0 |
HOH |
3.149 |
NH2 |
O |
||
| 2pfq | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:309 | A:549 | 159.0 | 0.707 | E | -90.4 | 128.3 | 159.0 | 0.707 | 0.0 |
HOH |
3.354 |
C |
O |
||
| 3hw8 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:309 | A:549 | 156.0 | 0.693 | E | -108.6 | 137.6 | 156.0 | 0.693 | 0.0 |
HOH |
2.667 |
NH2 |
O |
||
| 3hwt | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:309 | A:549 | 154.0 | 0.684 | E | -118.1 | 142.3 | 154.0 | 0.684 | 0.0 |
HOH |
2.900 |
NH1 |
O |
||
| 1rzt | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2004-03-02 | ARG | M:305 | A:549 | 202.0 | 0.898 | -93.0 | 138.9 | 202.0 | 0.898 | 0.0 |
HOH |
2.789 |
NH2 |
O |
|||
| ARG | N:305 | E:549 | 195.0 | 0.867 | -80.0 | 133.3 | NA | NA | NA | ||||||||||||||
| ARG | O:305 | I:549 | 202.0 | 0.898 | -77.0 | 139.2 | NA | NA | NA | ||||||||||||||
| ARG | P:305 | M:549 | 187.0 | 0.831 | -80.4 | 143.0 | NA | NA | NA | ||||||||||||||
| 4k4g | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:306 | A:549 | 208.0 | 0.924 | -110.7 | 149.3 | 208.0 | 0.924 | 0.0 |
HOH |
6.682 |
O |
O |
|||
| ARG | E:306 | E:549 | 172.0 | 0.764 | -80.9 | 143.4 | NA | NA | NA | ||||||||||||||
| ARG | I:306 | I:549 | 209.0 | 0.929 | -95.8 | 144.1 | NA | NA | NA | ||||||||||||||
| ARG | M:306 | M:549 | 202.0 | 0.898 | -75.4 | 133.7 | NA | NA | NA | ||||||||||||||
| 4k4h | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:306 | A:549 | 213.0 | 0.947 | E | -111.7 | 146.6 | 213.0 | 0.947 | 0.0 |
HOH |
4.468 |
N |
O |
||
| ARG | E:306 | E:549 | 164.0 | 0.729 | -71.5 | 138.3 | NA | NA | NA | ||||||||||||||
| ARG | I:306 | I:549 | 211.0 | 0.938 | -102.5 | 150.4 | NA | NA | NA | ||||||||||||||
| ARG | M:306 | M:549 | 202.0 | 0.898 | -83.9 | 129.3 | NA | NA | NA | ||||||||||||||
| 4k4i | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:306 | A:549 | 217.0 | 0.964 | 85.7 | 129.3 | 217.0 | 0.964 | 0.0 |
HOH |
3.292 |
CA |
O |
|||
| ARG | E:306 | E:549 | 174.0 | 0.773 | 60.5 | 143.0 | NA | NA | NA | ||||||||||||||
| ARG | I:306 | I:549 | 212.0 | 0.942 | -114.1 | 153.3 | NA | NA | NA | ||||||||||||||
| ARG | M:306 | M:549 | 204.0 | 0.907 | -86.7 | 136.2 | NA | NA | NA | ||||||||||||||
| 3hx0 | 1 | Q9UGP5 | 98.8 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:309 | A:549 | 168.0 | 0.747 | -81.1 | 114.5 | 168.0 | 0.747 | 0.0 | |||||||
| ARG | E:309 | F:549 | 163.0 | 0.724 | -100.8 | 112.7 | NA | NA | NA | ||||||||||||||
| ARG | I:309 | K:549 | 206.0 | 0.916 | -76.2 | 144.4 | NA | NA | NA | ||||||||||||||
| ARG | M:309 | P:549 | 198.0 | 0.88 | -63.7 | 131.0 | NA | NA | NA | ||||||||||||||
| 5dkw | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:301 | A:549 | 175.0 | 0.778 | -92.2 | 125.3 | 175.0 | 0.778 | 0.0 |
HOH |
6.788 |
O |
O |
|||
| ARG | B:301 | B:549 | 159.0 | 0.707 | -118.0 | 122.0 | NA | NA | NA | ||||||||||||||
| 5cb1 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:300 | A:549 | 158.0 | 0.702 | -103.7 | 152.4 | 158.0 | 0.702 | 0.0 | |||||||
| ARG | B:300 | B:549 | 145.0 | 0.644 | -76.9 | 153.1 | NA | NA | NA | ||||||||||||||
| 4x5v | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2015-10-28 | ARG | A:299 | A:549 | 150.0 | 0.667 | E | -152.3 | 123.0 | 150.0 | 0.667 | 0.0 |
HOH |
2.994 |
NH2 |
O |
||
| 4xa5 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-10 | ARG | A:299 | A:549 | 167.0 | 0.742 | -121.2 | 133.8 | 167.0 | 0.742 | 0.0 |
HOH |
3.685 |
CA |
O |
|||
| 4xus | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-03 | ARG | A:299 | A:549 | 154.0 | 0.684 | E | -110.4 | 139.3 | 154.0 | 0.684 | 0.0 |
HOH |
2.717 |
NH2 |
O |
||
| 5cwr | 1 | Q9UGP5 | 99.69 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:300 | A:549 | 203.0 | 0.902 | -77.1 | 133.6 | 203.0 | 0.902 | 0.0 |
HOH |
3.521 |
NE |
O |
|||
| ARG | D:300 | B:549 | 186.0 | 0.827 | -82.4 | 123.0 | NA | NA | NA | ||||||||||||||
| 3mda | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2010-04-28 | ARG | A:299 | A:549 | 155.0 | 0.689 | E | -108.7 | 140.4 | 155.0 | 0.689 | 0.0 |
HOH |
3.281 |
NH1 |
O |
||
| 3mdc | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2010-04-28 | ARG | A:299 | A:549 | 167.0 | 0.742 | -108.9 | 132.0 | 167.0 | 0.742 | 0.0 |
HOH |
2.903 |
NH1 |
O |
|||
| 3mgh | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2010-05-19 | ARG | A:303 | A:549 | 184.0 | 0.818 | -74.9 | 136.9 | 184.0 | 0.818 | 0.0 |
HOH |
6.295 |
O |
O |
|||
| ARG | E:303 | C:549 | 202.0 | 0.898 | -85.9 | 141.3 | NA | NA | NA | ||||||||||||||
| 3mgi | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2010-05-19 | ARG | A:303 | A:549 | 155.0 | 0.689 | E | -104.0 | 144.0 | 155.0 | 0.689 | 0.0 |
HOH |
6.465 |
O |
O |
||
| 3pml | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-01-26 | ARG | A:303 | A:549 | 214.0 | 0.951 | -80.7 | 151.0 | 214.0 | 0.951 | 0.0 |
HOH |
6.815 |
O |
O |
|||
| ARG | B:303 | B:549 | 207.0 | 0.92 | -70.8 | 144.0 | NA | NA | NA | ||||||||||||||
| 3pmn | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-02-02 | ARG | A:303 | A:549 | 173.0 | 0.769 | -102.4 | 152.1 | 173.0 | 0.769 | 0.0 |
HOH |
3.594 |
CB |
O |
|||
| 3pnc | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-02-02 | ARG | A:303 | A:549 | 156.0 | 0.693 | E | -103.1 | 144.5 | 156.0 | 0.693 | 0.0 |
HOH |
3.591 |
CA |
O |
||
| 3upq | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2012-05-23 | ARG | A:303 | A:549 | 171.0 | 0.76 | -102.1 | 134.9 | 171.0 | 0.76 | 0.0 |
HOH |
3.561 |
NH1 |
O |
|||
| 3uq0 | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2012-05-23 | ARG | A:303 | A:549 | 178.0 | 0.791 | -103.9 | 135.5 | 178.0 | 0.791 | 0.0 |
HOH |
6.692 |
O |
O |
|||
| 3uq2 | 1 | Q9UGP5 | 97.31 | 0.0 |
X-RAY |
2012-05-23 | ARG | A:303 | A:549 | 160.0 | 0.711 | E | -122.7 | 148.4 | 160.0 | 0.711 | 0.0 |
HOH |
7.090 |
O |
O |
||
| 4fo6 | 1 | Q9UGP5 | 97.31 | 0.0 |
X-RAY |
2012-07-11 | ARG | A:303 | A:549 | 158.0 | 0.702 | E | -138.2 | 150.7 | 158.0 | 0.702 | 0.0 |
HOH |
4.084 |
CB |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q9ugp5-f1 | 1 | Q9UGP5 | 100.0 | 0.0 | ARG | A:549 | A:549 | 175.0 | 0.778 | E | -114.6 | 135.6 | |