Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 103339440 | . | C | A | CCDS7513.1:NM_001174084.1:c.1498Gcc>Tcc_NP_001167555.1:p.500A>S | Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xq8 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:259 | B:500 | 3.0 | 0.026 | H | -63.0 | -52.1 | 3.0 | 0.026 | 0.0 |
HOH |
7.195 |
O |
O |
||
| ALA | B:259 | A:500 | 5.0 | 0.043 | H | -54.9 | -49.4 | NA | NA | NA | |||||||||||||
| 5ca7 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:259 | B:500 | 4.0 | 0.035 | H | -63.4 | -49.1 | 4.0 | 0.035 | 0.0 |
HOH |
4.522 |
CB |
O |
||
| ALA | B:259 | A:500 | 3.0 | 0.026 | H | -58.1 | -47.4 | NA | NA | NA | |||||||||||||
| 5iii | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ALA | A:259 | A:500 | 4.0 | 0.035 | H | -61.3 | -43.9 | 4.0 | 0.035 | 0.0 |
HOH |
2.863 |
N |
O |
||
| 5iij | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ALA | A:259 | A:500 | 3.0 | 0.026 | H | -59.4 | -46.3 | 3.0 | 0.026 | 0.0 |
HOH |
2.904 |
N |
O |
||
| 5iik | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ALA | A:259 | A:500 | 2.0 | 0.017 | H | -60.2 | -44.3 | 2.0 | 0.017 | 0.0 |
HOH |
2.832 |
N |
O |
||
| 5iil | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ALA | A:259 | A:500 | 2.0 | 0.017 | H | -63.9 | -42.7 | 2.0 | 0.017 | 0.0 |
HOH |
2.867 |
N |
O |
||
| 5iim | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-09-07 | ALA | A:259 | A:500 | 3.0 | 0.026 | H | -65.7 | -43.8 | 3.0 | 0.026 | 0.0 |
HOH |
2.870 |
N |
O |
||
| 5iin | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ALA | A:259 | A:500 | 3.0 | 0.026 | H | -58.6 | -48.4 | 3.0 | 0.026 | 0.0 |
HOH |
2.867 |
N |
O |
||
| 5iio | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ALA | M:259 | A:500 | 3.0 | 0.026 | H | -60.6 | -46.7 | 3.0 | 0.026 | 0.0 |
HOH |
2.981 |
N |
O |
||
| ALA | N:259 | E:500 | 2.0 | 0.017 | H | -62.2 | -49.5 | NA | NA | NA | |||||||||||||
| ALA | O:259 | I:500 | 3.0 | 0.026 | H | -63.9 | -49.3 | NA | NA | NA | |||||||||||||
| ALA | P:259 | M:500 | 3.0 | 0.026 | H | -61.3 | -44.3 | NA | NA | NA | |||||||||||||
| 1xsl | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2005-01-18 | ALA | M:260 | A:500 | 1.0 | 0.009 | H | -55.2 | -58.5 | 1.0 | 0.009 | 0.0 |
HOH |
2.725 |
N |
O |
||
| ALA | N:260 | E:500 | 1.0 | 0.009 | H | -52.3 | -55.1 | NA | NA | NA | |||||||||||||
| ALA | O:260 | I:500 | 2.0 | 0.017 | H | -59.8 | -54.4 | NA | NA | NA | |||||||||||||
| ALA | P:260 | M:500 | 3.0 | 0.026 | H | -57.1 | -47.7 | NA | NA | NA | |||||||||||||
| 2bcq | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ALA | D:260 | A:500 | 3.0 | 0.026 | H | -59.4 | -49.6 | 3.0 | 0.026 | 0.0 |
EDO HOH |
9.702 2.852 |
C N |
O1 O |
||
| 2bcr | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ALA | D:260 | A:500 | 3.0 | 0.026 | H | -61.2 | -48.4 | 3.0 | 0.026 | 0.0 |
EDO EDO HOH |
9.546 6.713 2.686 |
C CB N |
C1 O1 O |
||
| 2bcs | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ALA | D:260 | A:500 | 3.0 | 0.026 | H | -61.6 | -49.8 | 3.0 | 0.026 | 0.0 |
HOH |
2.884 |
N |
O |
||
| 2bcu | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ALA | D:260 | A:500 | 2.0 | 0.017 | H | -55.2 | -56.6 | 2.0 | 0.017 | 0.0 |
HOH |
2.842 |
N |
O |
||
| 2bcv | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ALA | D:260 | A:500 | 4.0 | 0.035 | H | -57.7 | -58.4 | 4.0 | 0.035 | 0.0 |
HOH |
2.794 |
N |
O |
||
| 2gws | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-09-05 | ALA | M:260 | A:500 | 2.0 | 0.017 | H | -55.5 | -52.7 | 2.0 | 0.017 | 0.0 |
CL HOH |
4.862 2.896 |
CB N |
CL O |
||
| ALA | N:260 | E:500 | 0.0 | 0.0 | H | -55.1 | -50.0 | NA | NA | NA | |||||||||||||
| ALA | O:260 | I:500 | 2.0 | 0.017 | H | -56.9 | -50.3 | NA | NA | NA | |||||||||||||
| ALA | P:260 | M:500 | 4.0 | 0.035 | H | -56.4 | -48.6 | NA | NA | NA | |||||||||||||
| 4xrh | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:260 | B:500 | 4.0 | 0.035 | H | -64.0 | -58.1 | 4.0 | 0.035 | 0.0 | ||||||
| ALA | B:260 | A:500 | 3.0 | 0.026 | H | -59.1 | -46.3 | NA | NA | NA | |||||||||||||
| 5ddm | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:260 | B:500 | 3.0 | 0.026 | H | -72.3 | -55.0 | 3.0 | 0.026 | 0.0 |
HOH |
4.740 |
CB |
O |
||
| ALA | B:260 | A:500 | 3.0 | 0.026 | H | -53.5 | -45.9 | NA | NA | NA | |||||||||||||
| 5ddy | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:260 | A:500 | 2.0 | 0.017 | H | -59.8 | -43.4 | 2.0 | 0.017 | 0.0 | ||||||
| ALA | B:260 | C:500 | 1.0 | 0.009 | H | -58.8 | -49.6 | NA | NA | NA | |||||||||||||
| ALA | C:260 | E:500 | 1.0 | 0.009 | H | -60.6 | -46.4 | NA | NA | NA | |||||||||||||
| ALA | D:260 | G:500 | 2.0 | 0.017 | H | -65.2 | -43.3 | NA | NA | NA | |||||||||||||
| 3c5g | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2008-07-29 | ALA | A:260 | A:500 | 2.0 | 0.017 | H | -57.4 | -49.6 | 2.0 | 0.017 | 0.0 |
HOH |
2.795 |
N |
O |
||
| ALA | E:260 | B:500 | 3.0 | 0.026 | H | -56.8 | -49.8 | NA | NA | NA | |||||||||||||
| 5chg | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:259 | A:500 | 2.0 | 0.017 | H | -68.5 | -49.4 | 2.0 | 0.017 | 0.0 |
HOH |
7.306 |
CB |
O |
||
| ALA | B:259 | B:500 | 4.0 | 0.035 | H | -59.2 | -43.6 | NA | NA | NA | |||||||||||||
| 5cj7 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:259 | A:500 | 3.0 | 0.026 | H | -66.9 | -50.4 | 3.0 | 0.026 | 0.0 | ||||||
| ALA | B:259 | B:500 | 3.0 | 0.026 | H | -55.7 | -42.9 | NA | NA | NA | |||||||||||||
| 5cp2 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:259 | A:500 | 4.0 | 0.035 | H | -57.6 | -46.9 | 4.0 | 0.035 | 0.0 |
HOH |
2.857 |
N |
O |
||
| ALA | B:259 | B:500 | 3.0 | 0.026 | H | -65.1 | -51.0 | NA | NA | NA | |||||||||||||
| 5cr0 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:259 | A:500 | 2.0 | 0.017 | H | -69.3 | -53.8 | 2.0 | 0.017 | 0.0 | ||||||
| ALA | B:259 | B:500 | 3.0 | 0.026 | H | -62.1 | -39.8 | NA | NA | NA | |||||||||||||
| 3c5f | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2008-09-02 | ALA | G:260 | A:500 | 2.0 | 0.017 | H | -58.3 | -52.2 | 2.0 | 0.017 | 0.0 |
NA HOH |
6.206 2.914 |
N N |
NA O |
||
| ALA | H:260 | B:500 | 4.0 | 0.035 | H | -58.0 | -51.8 | NA | NA | NA | |||||||||||||
| 1xsn | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2005-01-18 | ALA | D:260 | A:500 | 3.0 | 0.026 | H | -59.3 | -52.2 | 3.0 | 0.026 | 0.0 |
HOH |
2.835 |
N |
O |
||
| 1xsp | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2005-01-18 | ALA | D:260 | A:500 | 4.0 | 0.035 | H | -66.5 | -48.5 | 4.0 | 0.035 | 0.0 |
HOH |
2.840 |
N |
O |
||
| 2pfn | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ALA | D:260 | A:500 | 4.0 | 0.035 | H | -61.4 | -46.5 | 4.0 | 0.035 | 0.0 |
HOH |
2.899 |
N |
O |
||
| 2pfo | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ALA | D:260 | A:500 | 3.0 | 0.026 | H | -64.9 | -42.5 | 3.0 | 0.026 | 0.0 |
HOH |
2.787 |
N |
O |
||
| 2pfp | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ALA | D:260 | A:500 | 2.0 | 0.017 | H | -58.2 | -45.7 | 2.0 | 0.017 | 0.0 |
HOH |
2.870 |
N |
O |
||
| 2pfq | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ALA | D:260 | A:500 | 4.0 | 0.035 | H | -54.1 | -61.3 | 4.0 | 0.035 | 0.0 |
HOH |
3.094 |
CB |
O |
||
| 3hw8 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:260 | A:500 | 3.0 | 0.026 | H | -57.6 | -53.1 | 3.0 | 0.026 | 0.0 |
HOH |
3.067 |
N |
O |
||
| 3hwt | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:260 | A:500 | 4.0 | 0.035 | H | -59.8 | -50.8 | 4.0 | 0.035 | 0.0 |
HOH |
2.835 |
N |
O |
||
| 1rzt | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2004-03-02 | ALA | M:256 | A:500 | 1.0 | 0.009 | H | -59.9 | -47.9 | 1.0 | 0.009 | 0.0 |
HOH |
2.954 |
N |
O |
||
| ALA | N:256 | E:500 | 0.0 | 0.0 | H | -54.2 | -54.3 | NA | NA | NA | |||||||||||||
| ALA | O:256 | I:500 | 2.0 | 0.017 | H | -61.3 | -43.2 | NA | NA | NA | |||||||||||||
| ALA | P:256 | M:500 | 2.0 | 0.017 | H | -57.2 | -48.0 | NA | NA | NA | |||||||||||||
| 4k4g | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ALA | A:257 | A:500 | 3.0 | 0.026 | H | -69.8 | -45.4 | 3.0 | 0.026 | 0.0 |
HOH |
2.921 |
N |
O |
||
| ALA | E:257 | E:500 | 5.0 | 0.043 | H | -60.3 | -53.2 | NA | NA | NA | |||||||||||||
| ALA | I:257 | I:500 | 4.0 | 0.035 | H | -65.5 | -47.0 | NA | NA | NA | |||||||||||||
| ALA | M:257 | M:500 | 3.0 | 0.026 | H | -62.4 | -43.6 | NA | NA | NA | |||||||||||||
| 4k4h | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ALA | A:257 | A:500 | 4.0 | 0.035 | H | -68.0 | -42.5 | 4.0 | 0.035 | 0.0 |
ACT HOH |
4.138 2.898 |
CA N |
O O |
||
| ALA | E:257 | E:500 | 4.0 | 0.035 | H | -65.8 | -57.5 | NA | NA | NA | |||||||||||||
| ALA | I:257 | I:500 | 3.0 | 0.026 | H | -70.8 | -45.8 | NA | NA | NA | |||||||||||||
| ALA | M:257 | M:500 | 3.0 | 0.026 | H | -63.1 | -42.1 | NA | NA | NA | |||||||||||||
| 4k4i | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ALA | A:257 | A:500 | 4.0 | 0.035 | H | -65.8 | -39.9 | 4.0 | 0.035 | 0.0 |
ACT HOH |
3.969 2.838 |
CA N |
O O |
||
| ALA | E:257 | E:500 | 4.0 | 0.035 | H | -83.9 | -55.0 | NA | NA | NA | |||||||||||||
| ALA | I:257 | I:500 | 3.0 | 0.026 | H | -63.2 | -46.2 | NA | NA | NA | |||||||||||||
| ALA | M:257 | M:500 | 2.0 | 0.017 | H | -64.2 | -43.4 | NA | NA | NA | |||||||||||||
| 3hx0 | 1 | Q9UGP5 | 98.8 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:260 | A:500 | 4.0 | 0.035 | H | -55.7 | -38.2 | 4.0 | 0.035 | 0.0 |
HOH |
4.587 |
CA |
O |
||
| ALA | E:260 | F:500 | 4.0 | 0.035 | H | -57.1 | -51.8 | NA | NA | NA | |||||||||||||
| ALA | I:260 | K:500 | 4.0 | 0.035 | H | -50.3 | -56.2 | NA | NA | NA | |||||||||||||
| ALA | M:260 | P:500 | 4.0 | 0.035 | H | -58.6 | -70.3 | NA | NA | NA | |||||||||||||
| 5dkw | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:252 | A:500 | 3.0 | 0.026 | H | -62.6 | -44.5 | 3.0 | 0.026 | 0.0 |
HOH |
3.625 |
N |
O |
||
| ALA | B:252 | B:500 | 4.0 | 0.035 | H | -66.0 | -37.6 | NA | NA | NA | |||||||||||||
| 5cb1 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:251 | A:500 | 1.0 | 0.009 | H | -63.2 | -41.4 | 1.0 | 0.009 | 0.0 | ||||||
| ALA | B:251 | B:500 | 1.0 | 0.009 | H | -59.3 | -39.3 | NA | NA | NA | |||||||||||||
| 4x5v | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2015-10-28 | ALA | A:250 | A:500 | 2.0 | 0.017 | H | -63.9 | -43.2 | 2.0 | 0.017 | 0.0 |
HOH |
2.996 |
N |
O |
||
| 4xa5 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-10 | ALA | A:250 | A:500 | 3.0 | 0.026 | H | -61.2 | -45.1 | 3.0 | 0.026 | 0.0 |
HOH |
2.840 |
N |
O |
||
| 4xus | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-03 | ALA | A:250 | A:500 | 2.0 | 0.017 | H | -61.9 | -42.1 | 2.0 | 0.017 | 0.0 |
HOH |
3.020 |
N |
O |
||
| 5cwr | 1 | Q9UGP5 | 99.69 | 0.0 |
X-RAY |
2016-02-24 | ALA | A:251 | A:500 | 4.0 | 0.035 | H | -59.4 | -39.3 | 4.0 | 0.035 | 0.0 |
HOH |
2.939 |
N |
O |
||
| ALA | D:251 | B:500 | 5.0 | 0.043 | H | -52.0 | -57.5 | NA | NA | NA | |||||||||||||
| 3mda | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2010-04-28 | ALA | A:250 | A:500 | 3.0 | 0.026 | H | -62.8 | -45.3 | 3.0 | 0.026 | 0.0 |
HOH |
2.718 |
N |
O |
||
| 3mdc | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2010-04-28 | ALA | A:250 | A:500 | 4.0 | 0.035 | H | -69.6 | -42.1 | 4.0 | 0.035 | 0.0 |
HOH |
3.014 |
N |
O |
||
| 3mgh | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2010-05-19 | ALA | A:254 | A:500 | 2.0 | 0.017 | H | -66.6 | -53.1 | 2.0 | 0.017 | 0.0 |
HOH |
2.787 |
N |
O |
||
| ALA | E:254 | C:500 | 2.0 | 0.017 | H | -51.8 | -53.2 | NA | NA | NA | |||||||||||||
| 3mgi | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2010-05-19 | ALA | A:254 | A:500 | 3.0 | 0.026 | H | -51.6 | -49.1 | 3.0 | 0.026 | 0.0 |
HOH |
2.872 |
N |
O |
||
| 3pml | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-01-26 | ALA | A:254 | A:500 | 3.0 | 0.026 | H | -56.3 | -52.1 | 3.0 | 0.026 | 0.0 |
HOH |
4.921 |
CB |
O |
||
| ALA | B:254 | B:500 | 2.0 | 0.017 | H | -60.1 | -58.9 | NA | NA | NA | |||||||||||||
| 3pmn | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-02-02 | ALA | A:254 | A:500 | 2.0 | 0.017 | H | -49.6 | -48.7 | 2.0 | 0.017 | 0.0 |
HOH |
2.958 |
N |
O |
||
| 3pnc | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-02-02 | ALA | A:254 | A:500 | 4.0 | 0.035 | H | -57.7 | -48.2 | 4.0 | 0.035 | 0.0 |
HOH |
2.776 |
N |
O |
||
| 3upq | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2012-05-23 | ALA | A:254 | A:500 | 3.0 | 0.026 | H | -60.5 | -43.8 | 3.0 | 0.026 | 0.0 |
HOH |
2.926 |
N |
O |
||
| 3uq0 | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2012-05-23 | ALA | A:254 | A:500 | 3.0 | 0.026 | H | -65.6 | -44.3 | 3.0 | 0.026 | 0.0 |
HOH |
2.976 |
N |
O |
||
| 3uq2 | 1 | Q9UGP5 | 97.31 | 0.0 |
X-RAY |
2012-05-23 | ALA | A:254 | A:500 | 2.0 | 0.017 | H | -71.4 | -40.5 | 2.0 | 0.017 | 0.0 |
HOH |
3.754 |
N |
O |
||
| 4fo6 | 1 | Q9UGP5 | 97.31 | 0.0 |
X-RAY |
2012-07-11 | ALA | A:254 | A:500 | 3.0 | 0.026 | H | -68.4 | -39.6 | 3.0 | 0.026 | 0.0 |
DT DG HOH |
9.929 5.863 3.012 |
CB CB N |
O3' O3' O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q9ugp5-f1 | 1 | Q9UGP5 | 100.0 | 0.0 | ALA | A:500 | A:500 | 1.0 | 0.009 | H | -63.0 | -42.3 | |