Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 103339478 . C A CCDS7513.1:NM_001174084.1:c.1460cGg>cTg_NP_001167555.1:p.487R>L Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xq8 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ARG A:246 B:487 18.0 0.08 E -111.7 148.6 18.0 0.08 0.0 DA
HOH
 9.598
3.196
 C
NH1
 OP1
O
ARG B:246 A:487 19.0 0.084 E -127.6 138.8 NA NA NA
5ca7 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ARG A:246 B:487 17.0 0.076 E -124.1 143.5 17.0 0.076 0.0 DA
HOH
 9.549
3.028
 C
NH2
 OP1
O
ARG B:246 A:487 18.0 0.08 E -116.7 136.1 NA NA NA
5iii 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ARG A:246 A:487 17.0 0.076 E -127.5 144.9 17.0 0.076 0.0 DOC
HOH
 9.847
2.956
 C
NH1
 OP1
O
5iij 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ARG A:246 A:487 19.0 0.084 E -121.2 144.9 19.0 0.084 0.0 HOH
 2.964
 NH1
 O
5iik 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ARG A:246 A:487 20.0 0.089 E -121.8 141.3 20.0 0.089 0.0 DC
CIT
HOH
 9.815
9.507
2.801
 C
C
NH2
 OP1
O1
O
5iil 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ARG A:246 A:487 20.0 0.089 E -121.5 142.4 20.0 0.089 0.0 DA
CIT
HOH
 9.910
9.476
2.718
 C
C
NH2
 OP1
O1
O
5iim 1 Q9UGP5 100.0 0.0 X-RAY
 2016-09-07 ARG A:246 A:487 25.0 0.111 E -127.1 147.4 25.0 0.111 0.0 DA
HOH
 9.884
3.016
 C
NH1
 OP1
O
5iin 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ARG A:246 A:487 16.0 0.071 E -124.7 149.0 16.0 0.071 0.0 DC
HOH
 9.824
3.044
 C
NH1
 OP1
O
5iio 4 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ARG M:246 A:487 11.0 0.049 E -129.3 148.3 11.0 0.049 0.0 DC
HOH
 9.714
2.979
 C
NH1
 OP1
O
ARG N:246 E:487 18.0 0.08 E -125.7 145.2 NA NA NA
ARG O:246 I:487 19.0 0.084 E -124.9 150.5 NA NA NA
ARG P:246 M:487 17.0 0.076 E -125.4 144.5 NA NA NA
1xsl 4 Q9UGP5 100.0 0.0 X-RAY
 2005-01-18 ARG M:247 A:487 11.0 0.049 E -133.9 152.9 11.0 0.049 0.0 DC
HOH
 9.516
3.009
 C
NH1
 OP1
O
ARG N:247 E:487 18.0 0.08 E -134.9 147.3 NA NA NA
ARG O:247 I:487 20.0 0.089 E -120.6 152.0 NA NA NA
ARG P:247 M:487 16.0 0.071 E -133.2 151.2 NA NA NA
2bcq 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ARG D:247 A:487 23.0 0.102 E -123.4 155.4 23.0 0.102 0.0 DC
PPV
HOH
 9.741
9.961
2.814
 C
C
NH1
 OP1
O31
O
2bcr 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ARG D:247 A:487 23.0 0.102 E -121.5 148.5 23.0 0.102 0.0 DC
HOH
 9.904
2.900
 C
NH2
 OP1
O
2bcs 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ARG D:247 A:487 24.0 0.107 E -120.9 149.4 24.0 0.107 0.0 DC
HOH
 9.857
3.055
 C
NH1
 OP1
O
2bcu 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ARG D:247 A:487 21.0 0.093 E -123.4 147.9 21.0 0.093 0.0 DC
HOH
 9.826
2.867
 C
NH2
 OP1
O
2bcv 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ARG D:247 A:487 25.0 0.111 E -118.7 142.5 25.0 0.111 0.0 NA
HOH
 9.915
2.909
 C
NH1
 NA
O
2gws 4 Q9UGP5 100.0 0.0 X-RAY
 2006-09-05 ARG M:247 A:487 14.0 0.062 E -135.3 151.6 14.0 0.062 0.0 DG
HOH
 9.450
3.397
 C
NH2
 OP1
O
ARG N:247 E:487 30.0 0.133 E -129.1 158.9 NA NA NA
ARG O:247 I:487 22.0 0.098 E -117.2 146.4 NA NA NA
ARG P:247 M:487 16.0 0.071 E -126.9 148.3 NA NA NA
4xrh 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ARG A:247 B:487 19.0 0.084 E -117.1 152.8 19.0 0.084 0.0 DA
 9.583
 C
 OP1
ARG B:247 A:487 17.0 0.076 E -112.2 135.6 NA NA NA
5ddm 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ARG A:247 B:487 16.0 0.071 E -127.8 147.6 16.0 0.071 0.0 DA
HOH
 9.504
3.107
 C
NH1
 OP1
O
ARG B:247 A:487 20.0 0.089 E -116.3 135.5 NA NA NA
5ddy 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ARG A:247 A:487 20.0 0.089 E -118.4 133.0 20.0 0.089 0.0
ARG B:247 C:487 13.0 0.058 E -123.4 139.9 NA NA NA
ARG C:247 E:487 11.0 0.049 E -127.3 132.6 NA NA NA
ARG D:247 G:487 35.0 0.156 E -130.8 143.3 NA NA NA
3c5g 1 Q9UGP5 99.7 0.0 X-RAY
 2008-07-29 ARG A:247 A:487 11.0 0.049 E -135.3 151.1 11.0 0.049 0.0 2DT
MG
NA
HOH
 9.890
9.929
9.371
3.163
 C
C
C
NH1
 OP1
MG
NA
O
ARG E:247 B:487 10.0 0.044 E -136.1 153.3 NA NA NA
5chg 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ARG A:246 A:487 18.0 0.08 E -120.2 149.2 18.0 0.08 0.0 DA
HOH
 9.453
3.640
 C
NH2
 OP1
O
ARG B:246 B:487 14.0 0.062 E -114.4 140.3 NA NA NA
5cj7 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ARG A:246 A:487 15.0 0.067 E -126.1 150.0 15.0 0.067 0.0 DA
HOH
 9.431
4.954
 C
NH2
 OP1
O
ARG B:246 B:487 14.0 0.062 E -118.9 149.0 NA NA NA
5cp2 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ARG A:246 A:487 14.0 0.062 E -121.4 137.5 14.0 0.062 0.0 HOH
 3.037
 NH1
 O
ARG B:246 B:487 19.0 0.084 E -125.7 145.3 NA NA NA
5cr0 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ARG A:246 A:487 20.0 0.089 E -126.4 150.8 20.0 0.089 0.0 DA
 9.524
 C
 OP1
ARG B:246 B:487 15.0 0.067 E -121.5 138.4 NA NA NA
3c5f 4 Q9UGP5 99.7 0.0 X-RAY
 2008-09-02 ARG G:247 A:487 19.0 0.084 E -133.0 157.7 19.0 0.084 0.0 DC
HOH
 9.647
3.136
 C
NH1
 OP1
O
ARG H:247 B:487 9.0 0.04 E -131.8 157.2 NA NA NA
1xsn 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ARG D:247 A:487 25.0 0.111 E -122.9 145.8 25.0 0.111 0.0 2DT
HOH
 9.906
3.018
 C
NH1
 OP1
O
1xsp 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ARG D:247 A:487 24.0 0.107 E -121.9 148.3 24.0 0.107 0.0 DC
HOH
 9.898
2.835
 C
NH2
 OP1
O
2pfn 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ARG D:247 A:487 22.0 0.098 E -120.4 147.1 22.0 0.098 0.0 DC
MG
NA
HOH
 9.777
9.924
9.357
2.823
 C
C
C
NH2
 OP1
MG
NA
O
2pfo 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ARG D:247 A:487 21.0 0.093 E -126.5 151.8 21.0 0.093 0.0 DC
MN
EDO
HOH
 9.867
9.606
6.765
3.179
 C
C
NH1
NH1
 OP1
MN
O2
O
2pfp 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ARG D:247 A:487 23.0 0.102 E -127.2 150.4 23.0 0.102 0.0 DC
NA
HOH
 9.834
9.521
2.718
 C
C
NH2
 OP1
NA
O
2pfq 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ARG D:247 A:487 25.0 0.111 E -128.8 151.6 25.0 0.111 0.0 DC
NA
MN
HOH
 9.849
9.609
9.443
3.042
 C
C
C
NH2
 OP1
NA
MN
O
3hw8 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ARG A:247 A:487 22.0 0.098 E -121.2 147.5 22.0 0.098 0.0 NA
D3T
EDO
HOH
 9.630
9.917
7.026
2.819
 C
C
NH2
NH2
 NA
O3G
O1
O
3hwt 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ARG A:247 A:487 25.0 0.111 E -123.0 147.9 25.0 0.111 0.0 2DT
EDO
HOH
 9.921
6.122
2.766
 C
NH2
NH2
 OP1
O1
O
1rzt 4 Q9UGP5 100.0 0.0 X-RAY
 2004-03-02 ARG M:243 A:487 15.0 0.067 E -133.5 152.4 15.0 0.067 0.0 HOH
 3.032
 NH1
 O
ARG N:243 E:487 22.0 0.098 E -127.9 150.4 NA NA NA
ARG O:243 I:487 12.0 0.053 E -127.2 145.1 NA NA NA
ARG P:243 M:487 16.0 0.071 E -129.3 154.7 NA NA NA
4k4g 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ARG A:244 A:487 19.0 0.084 E -121.0 151.5 19.0 0.084 0.0 DC
CA
HOH
 9.749
9.668
3.568
 C
C
NH2
 OP1
CA
O
ARG E:244 E:487 17.0 0.076 E -127.4 152.2 NA NA NA
ARG I:244 I:487 8.0 0.036 E -131.9 150.5 NA NA NA
ARG M:244 M:487 14.0 0.062 E -125.2 150.3 NA NA NA
4k4h 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ARG A:244 A:487 16.0 0.071 E -119.8 145.5 16.0 0.071 0.0 DC
CA
HOH
 9.635
9.553
3.579
 C
C
NH2
 OP1
CA
O
ARG E:244 E:487 18.0 0.08 E -126.5 150.6 NA NA NA
ARG I:244 I:487 14.0 0.062 E -131.3 147.7 NA NA NA
ARG M:244 M:487 14.0 0.062 E -125.2 148.8 NA NA NA
4k4i 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ARG A:244 A:487 19.0 0.084 E -119.6 148.8 19.0 0.084 0.0 DC
CA
HOH
 9.613
9.648
3.600
 C
C
NH2
 OP1
CA
O
ARG E:244 E:487 15.0 0.067 E -126.3 146.9 NA NA NA
ARG I:244 I:487 9.0 0.04 E -125.1 151.4 NA NA NA
ARG M:244 M:487 12.0 0.053 E -131.6 152.1 NA NA NA
3hx0 1 Q9UGP5 98.8 0.0 X-RAY
 2009-08-25 ARG A:247 A:487 17.0 0.076 E -108.2 147.0 17.0 0.076 0.0 DT
HOH
 9.761
6.028
 C
NH1
 OP1
O
ARG E:247 F:487 17.0 0.076 E -116.3 145.0 NA NA NA
ARG I:247 K:487 22.0 0.098 E -130.1 148.1 NA NA NA
ARG M:247 P:487 9.0 0.04 E -98.4 152.0 NA NA NA
5dkw 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ARG A:239 A:487 13.0 0.058 E -128.6 148.8 13.0 0.058 0.0 DC
CA
HOH
 9.952
9.795
3.036
 C
C
NH1
 OP1
CA
O
ARG B:239 B:487 16.0 0.071 E -125.3 154.2 NA NA NA
5cb1 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ARG A:238 A:487 11.0 0.049 E -133.8 153.2 11.0 0.049 0.0
ARG B:238 B:487 10.0 0.044 E -137.2 142.5 NA NA NA
4x5v 1 Q9UGP5 100.0 0.0 X-RAY
 2015-10-28 ARG A:237 A:487 20.0 0.089 E -121.9 148.6 20.0 0.089 0.0 DC
CIT
HOH
 9.612
9.451
2.949
 C
C
NH1
 OP1
O2
O
4xa5 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-10 ARG A:237 A:487 17.0 0.076 E -124.1 147.2 17.0 0.076 0.0 DOC
MG
HOH
 9.776
9.926
2.646
 C
C
NH2
 OP1
MG
O
4xus 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-03 ARG A:237 A:487 19.0 0.084 E -112.6 145.3 19.0 0.084 0.0 HOH
 2.916
 NH1
 O
5cwr 1 Q9UGP5 99.69 0.0 X-RAY
 2016-02-24 ARG A:238 A:487 8.0 0.036 E -134.0 149.1 8.0 0.036 0.0 DC
CA
CA
HOH
 9.529
9.492
9.828
3.856
 C
C
C
CG
 OP1
CA
CA
O
ARG D:238 B:487 8.0 0.036 E -130.2 152.0 NA NA NA
3mda 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ARG A:237 A:487 23.0 0.102 E -122.5 147.1 23.0 0.102 0.0 DC
HOH
 9.949
2.791
 C
NH2
 OP1
O
3mdc 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ARG A:237 A:487 20.0 0.089 E -122.9 145.2 20.0 0.089 0.0 DC
MG
MG
NA
HOH
 9.841
9.308
9.910
6.870
2.841
 C
C
C
N
NH2
 OP1
MG
MG
NA
O
3mgh 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ARG A:241 A:487 14.0 0.062 E -124.9 142.9 14.0 0.062 0.0 DC
HOH
 9.958
2.858
 C
NH2
 OP1
O
ARG E:241 C:487 16.0 0.071 E -119.1 156.5 NA NA NA
3mgi 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ARG A:241 A:487 24.0 0.107 E -119.2 143.5 24.0 0.107 0.0 DT
MG
HOH
 9.541
9.653
3.153
 C
C
NH1
 OP1
MG
O
3pml 1 Q9UGP5 97.6 0.0 X-RAY
 2011-01-26 ARG A:241 A:487 14.0 0.062 E -111.4 132.7 14.0 0.062 0.0 DC
MG
HOH
 9.947
9.756
3.581
 C
C
CG
 OP1
MG
O
ARG B:241 B:487 19.0 0.084 E -109.6 139.9 NA NA NA
3pmn 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ARG A:241 A:487 20.0 0.089 E -125.3 149.1 20.0 0.089 0.0 DG
MN
MN
CL
HOH
 9.722
9.422
6.789
9.290
3.027
 C
C
N
N
NH1
 OP1
MN
MN
CL
O
3pnc 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ARG A:241 A:487 24.0 0.107 E -130.3 151.6 24.0 0.107 0.0 DG
NA
TRS
HOH
 9.612
9.249
7.460
3.204
 C
C
C
NH1
 OP1
NA
O3
O
3upq 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ARG A:241 A:487 15.0 0.067 E -124.9 144.5 15.0 0.067 0.0 DC
ZAN
MN
MN
HOH
 9.673
9.696
9.430
6.814
2.748
 C
C
C
N
NH2
 OP1
O2G
MN
MN
O
3uq0 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ARG A:241 A:487 19.0 0.084 E -123.7 147.8 19.0 0.084 0.0 HOH
 2.984
 NH2
 O
3uq2 1 Q9UGP5 97.31 0.0 X-RAY
 2012-05-23 ARG A:241 A:487 17.0 0.076 E -125.0 149.0 17.0 0.076 0.0 C
HOH
 9.453
3.935
 C
CG
 OP1
O
4fo6 1 Q9UGP5 97.31 0.0 X-RAY
 2012-07-11 ARG A:241 A:487 23.0 0.102 E -124.6 145.4 23.0 0.102 0.0 C
MN
HOH
 9.889
9.700
2.797
 C
C
NH1
 OP1
MN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugp5-f1 1 Q9UGP5 100.0 0.0 ARG A:487 A:487 18.0 0.08 E -121.3 147.5