Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 103339484 | . | C | A | CCDS7513.1:NM_001174084.1:c.1454cGg>cTg_NP_001167555.1:p.485R>L | Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xq8 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:244 | B:485 | 96.0 | 0.427 | -106.1 | 150.9 | 96.0 | 0.427 | 0.0 |
HOH |
2.179 |
O |
O |
|||
| ARG | B:244 | A:485 | 98.0 | 0.436 | -79.0 | 153.4 | NA | NA | NA | ||||||||||||||
| 5ca7 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:244 | B:485 | 98.0 | 0.436 | -89.1 | 159.0 | 98.0 | 0.436 | 0.0 |
HOH |
2.759 |
N |
O |
|||
| ARG | B:244 | A:485 | 89.0 | 0.396 | -95.9 | 154.9 | NA | NA | NA | ||||||||||||||
| 5iii | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:244 | A:485 | 114.0 | 0.507 | -105.3 | 160.2 | 114.0 | 0.507 | 0.0 |
HOH |
2.881 |
O |
O |
|||
| 5iij | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:244 | A:485 | 114.0 | 0.507 | -103.0 | 162.6 | 114.0 | 0.507 | 0.0 |
HOH |
2.831 |
O |
O |
|||
| 5iik | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:244 | A:485 | 116.0 | 0.516 | -104.6 | 163.0 | 116.0 | 0.516 | 0.0 |
HOH |
2.716 |
N |
O |
|||
| 5iil | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:244 | A:485 | 114.0 | 0.507 | -106.4 | 161.2 | 114.0 | 0.507 | 0.0 |
HOH |
2.789 |
N |
O |
|||
| 5iim | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-09-07 | ARG | A:244 | A:485 | 131.0 | 0.582 | -100.4 | 157.8 | 131.0 | 0.582 | 0.0 |
HOH |
2.757 |
O |
O |
|||
| 5iin | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | A:244 | A:485 | 116.0 | 0.516 | -98.5 | 157.2 | 116.0 | 0.516 | 0.0 |
HOH |
2.882 |
O |
O |
|||
| 5iio | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-08-17 | ARG | M:244 | A:485 | 99.0 | 0.44 | -91.1 | 156.3 | 99.0 | 0.44 | 0.0 |
HOH |
2.781 |
O |
O |
|||
| ARG | N:244 | E:485 | 94.0 | 0.418 | -93.6 | 159.7 | NA | NA | NA | ||||||||||||||
| ARG | O:244 | I:485 | 102.0 | 0.453 | -95.3 | 158.5 | NA | NA | NA | ||||||||||||||
| ARG | P:244 | M:485 | 99.0 | 0.44 | -83.1 | 154.3 | NA | NA | NA | ||||||||||||||
| 1xsl | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2005-01-18 | ARG | M:245 | A:485 | 96.0 | 0.427 | -90.9 | 165.7 | 96.0 | 0.427 | 0.0 |
HOH |
2.854 |
N |
O |
|||
| ARG | N:245 | E:485 | 91.0 | 0.404 | -101.8 | 160.8 | NA | NA | NA | ||||||||||||||
| ARG | O:245 | I:485 | 104.0 | 0.462 | -92.5 | 160.0 | NA | NA | NA | ||||||||||||||
| ARG | P:245 | M:485 | 117.0 | 0.52 | -89.9 | 162.8 | NA | NA | NA | ||||||||||||||
| 2bcq | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:245 | A:485 | 135.0 | 0.6 | -113.6 | 157.6 | 135.0 | 0.6 | 0.0 |
HOH |
2.791 |
N |
O |
|||
| 2bcr | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:245 | A:485 | 118.0 | 0.524 | -112.4 | 161.0 | 118.0 | 0.524 | 0.0 |
EDO HOH |
5.364 2.801 |
NH1 N |
O2 O |
|||
| 2bcs | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:245 | A:485 | 118.0 | 0.524 | -104.5 | 158.8 | 118.0 | 0.524 | 0.0 |
HOH |
2.778 |
N |
O |
|||
| 2bcu | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:245 | A:485 | 115.0 | 0.511 | -107.8 | 156.3 | 115.0 | 0.511 | 0.0 |
HOH |
2.816 |
NH2 |
O |
|||
| 2bcv | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-03-07 | ARG | D:245 | A:485 | 116.0 | 0.516 | -111.3 | 157.8 | 116.0 | 0.516 | 0.0 |
HOH |
2.716 |
N |
O |
|||
| 2gws | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2006-09-05 | ARG | M:245 | A:485 | 97.0 | 0.431 | -98.6 | 164.3 | 97.0 | 0.431 | 0.0 |
HOH |
2.897 |
N |
O |
|||
| ARG | N:245 | E:485 | 19.0 | NA | -93.2 | 168.7 | NA | NA | NA | ||||||||||||||
| ARG | O:245 | I:485 | 111.0 | 0.493 | -74.2 | 160.8 | NA | NA | NA | ||||||||||||||
| ARG | P:245 | M:485 | 125.0 | 0.556 | -90.2 | 164.3 | NA | NA | NA | ||||||||||||||
| 4xrh | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:245 | B:485 | 95.0 | 0.422 | -89.7 | 158.7 | 95.0 | 0.422 | 0.0 | |||||||
| ARG | B:245 | A:485 | 92.0 | 0.409 | -93.8 | 162.2 | NA | NA | NA | ||||||||||||||
| 5ddm | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:245 | B:485 | 96.0 | 0.427 | -90.2 | 151.3 | 96.0 | 0.427 | 0.0 |
HOH |
2.513 |
N |
O |
|||
| ARG | B:245 | A:485 | 96.0 | 0.427 | -100.7 | 163.1 | NA | NA | NA | ||||||||||||||
| 5ddy | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:245 | A:485 | 89.0 | 0.396 | -109.7 | 155.9 | 89.0 | 0.396 | 0.0 | |||||||
| ARG | B:245 | C:485 | 96.0 | 0.427 | -113.6 | 170.3 | NA | NA | NA | ||||||||||||||
| ARG | C:245 | E:485 | 84.0 | 0.373 | -135.6 | 152.6 | NA | NA | NA | ||||||||||||||
| ARG | D:245 | G:485 | 59.0 | 0.262 | -137.5 | 169.3 | NA | NA | NA | ||||||||||||||
| 3c5g | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2008-07-29 | ARG | A:245 | A:485 | 98.0 | 0.436 | -88.5 | 166.2 | 98.0 | 0.436 | 0.0 |
HOH |
2.816 |
N |
O |
|||
| ARG | E:245 | B:485 | 98.0 | 0.436 | -93.3 | 163.9 | NA | NA | NA | ||||||||||||||
| 5chg | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:244 | A:485 | 94.0 | 0.418 | -89.2 | 154.0 | 94.0 | 0.418 | 0.0 |
HOH |
3.052 |
N |
O |
|||
| ARG | B:244 | B:485 | 91.0 | 0.404 | -99.9 | 165.7 | NA | NA | NA | ||||||||||||||
| 5cj7 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:244 | A:485 | 93.0 | 0.413 | -98.7 | 156.5 | 93.0 | 0.413 | 0.0 |
HOH |
6.061 |
N |
O |
|||
| ARG | B:244 | B:485 | 93.0 | 0.413 | -100.3 | 160.0 | NA | NA | NA | ||||||||||||||
| 5cp2 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:244 | A:485 | 85.0 | 0.378 | -94.9 | 161.8 | 85.0 | 0.378 | 0.0 |
HOH |
2.703 |
N |
O |
|||
| ARG | B:244 | B:485 | 95.0 | 0.422 | -94.4 | 154.7 | NA | NA | NA | ||||||||||||||
| 5cr0 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:244 | A:485 | 98.0 | 0.436 | -100.5 | 156.6 | 98.0 | 0.436 | 0.0 |
HOH |
7.803 |
NH2 |
O |
|||
| ARG | B:244 | B:485 | 93.0 | 0.413 | -85.7 | 161.9 | NA | NA | NA | ||||||||||||||
| 3c5f | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2008-09-02 | ARG | G:245 | A:485 | 97.0 | 0.431 | -86.7 | 168.4 | 97.0 | 0.431 | 0.0 |
HOH |
2.881 |
NH2 |
O |
|||
| ARG | H:245 | B:485 | 94.0 | 0.418 | -83.2 | 161.1 | NA | NA | NA | ||||||||||||||
| 1xsn | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2005-01-18 | ARG | D:245 | A:485 | 129.0 | 0.573 | -109.1 | 162.5 | 129.0 | 0.573 | 0.0 |
HOH |
2.859 |
N |
O |
|||
| 1xsp | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2005-01-18 | ARG | D:245 | A:485 | 117.0 | 0.52 | -110.9 | 160.2 | 117.0 | 0.52 | 0.0 |
HOH |
2.810 |
N |
O |
|||
| 2pfn | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:245 | A:485 | 115.0 | 0.511 | -108.6 | 157.6 | 115.0 | 0.511 | 0.0 |
HOH |
2.677 |
N |
O |
|||
| 2pfo | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:245 | A:485 | 122.0 | 0.542 | -110.7 | 155.4 | 122.0 | 0.542 | 0.0 |
EDO HOH |
3.921 2.815 |
CZ N |
C1 O |
|||
| 2pfp | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:245 | A:485 | 115.0 | 0.511 | -109.1 | 157.3 | 115.0 | 0.511 | 0.0 |
HOH |
2.880 |
N |
O |
|||
| 2pfq | 4 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2007-05-15 | ARG | D:245 | A:485 | 114.0 | 0.507 | -114.6 | 163.8 | 114.0 | 0.507 | 0.0 |
HOH |
2.589 |
N |
O |
|||
| 3hw8 | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:245 | A:485 | 132.0 | 0.587 | -108.2 | 158.7 | 132.0 | 0.587 | 0.0 |
EDO HOH |
3.598 2.679 |
CZ N |
C2 O |
|||
| 3hwt | 1 | Q9UGP5 | 99.7 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:245 | A:485 | 125.0 | 0.556 | -110.1 | 158.2 | 125.0 | 0.556 | 0.0 |
EDO HOH |
3.148 2.829 |
NE N |
O1 O |
|||
| 1rzt | 4 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2004-03-02 | ARG | M:241 | A:485 | 103.0 | 0.458 | -98.7 | 162.7 | 103.0 | 0.458 | 0.0 |
HOH |
2.763 |
N |
O |
|||
| ARG | N:241 | E:485 | 88.0 | 0.391 | -101.5 | 156.1 | NA | NA | NA | ||||||||||||||
| ARG | O:241 | I:485 | 116.0 | 0.516 | -95.0 | 163.8 | NA | NA | NA | ||||||||||||||
| ARG | P:241 | M:485 | 105.0 | 0.467 | -90.1 | 158.9 | NA | NA | NA | ||||||||||||||
| 4k4g | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:242 | A:485 | 92.0 | 0.409 | -87.6 | 152.1 | 92.0 | 0.409 | 0.0 |
HOH |
2.585 |
O |
O |
|||
| ARG | E:242 | E:485 | 96.0 | 0.427 | -87.7 | 152.7 | NA | NA | NA | ||||||||||||||
| ARG | I:242 | I:485 | 96.0 | 0.427 | -87.8 | 161.5 | NA | NA | NA | ||||||||||||||
| ARG | M:242 | M:485 | 76.0 | 0.338 | -84.4 | 148.4 | NA | NA | NA | ||||||||||||||
| 4k4h | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:242 | A:485 | 86.0 | 0.382 | -86.4 | 154.8 | 86.0 | 0.382 | 0.0 |
HOH |
2.685 |
O |
O |
|||
| ARG | E:242 | E:485 | 98.0 | 0.436 | -92.1 | 149.4 | NA | NA | NA | ||||||||||||||
| ARG | I:242 | I:485 | 99.0 | 0.44 | -94.4 | 163.5 | NA | NA | NA | ||||||||||||||
| ARG | M:242 | M:485 | 80.0 | 0.356 | -94.6 | 156.2 | NA | NA | NA | ||||||||||||||
| 4k4i | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:242 | A:485 | 92.0 | 0.409 | -83.9 | 154.4 | 92.0 | 0.409 | 0.0 |
HOH |
2.575 |
O |
O |
|||
| ARG | E:242 | E:485 | 103.0 | 0.458 | -96.2 | 149.0 | NA | NA | NA | ||||||||||||||
| ARG | I:242 | I:485 | 104.0 | 0.462 | -100.4 | 159.1 | NA | NA | NA | ||||||||||||||
| ARG | M:242 | M:485 | 93.0 | 0.413 | -90.4 | 151.8 | NA | NA | NA | ||||||||||||||
| 3hx0 | 1 | Q9UGP5 | 98.8 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:245 | A:485 | 101.0 | 0.449 | -94.7 | 160.3 | 101.0 | 0.449 | 0.0 |
HOH |
8.927 |
CD |
O |
|||
| ARG | E:245 | F:485 | 90.0 | 0.4 | -120.2 | 156.6 | NA | NA | NA | ||||||||||||||
| ARG | I:245 | K:485 | 91.0 | 0.404 | -122.0 | 152.0 | NA | NA | NA | ||||||||||||||
| ARG | M:245 | P:485 | 98.0 | 0.436 | -105.8 | 140.6 | NA | NA | NA | ||||||||||||||
| 5dkw | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:237 | A:485 | 102.0 | 0.453 | -96.7 | 162.6 | 102.0 | 0.453 | 0.0 |
HOH |
2.733 |
O |
O |
|||
| ARG | B:237 | B:485 | 103.0 | 0.458 | -96.6 | 156.0 | NA | NA | NA | ||||||||||||||
| 5cb1 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:236 | A:485 | 93.0 | 0.413 | -115.9 | 154.8 | 93.0 | 0.413 | 0.0 | |||||||
| ARG | B:236 | B:485 | 102.0 | 0.453 | -108.6 | 153.4 | NA | NA | NA | ||||||||||||||
| 4x5v | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2015-10-28 | ARG | A:235 | A:485 | 112.0 | 0.498 | -109.3 | 159.0 | 112.0 | 0.498 | 0.0 |
HOH |
2.700 |
N |
O |
|||
| 4xa5 | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-10 | ARG | A:235 | A:485 | 120.0 | 0.533 | -103.9 | 161.9 | 120.0 | 0.533 | 0.0 |
HOH |
2.859 |
O |
O |
|||
| 4xus | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2016-02-03 | ARG | A:235 | A:485 | 110.0 | 0.489 | -108.6 | 164.7 | 110.0 | 0.489 | 0.0 |
HOH |
2.763 |
NH1 |
O |
|||
| 5cwr | 1 | Q9UGP5 | 99.69 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:236 | A:485 | 87.0 | 0.387 | -83.7 | 158.7 | 87.0 | 0.387 | 0.0 |
HOH |
2.740 |
N |
O |
|||
| ARG | D:236 | B:485 | 83.0 | 0.369 | -79.0 | 157.0 | NA | NA | NA | ||||||||||||||
| 3mda | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2010-04-28 | ARG | A:235 | A:485 | 118.0 | 0.524 | -105.0 | 158.2 | 118.0 | 0.524 | 0.0 |
HOH |
2.892 |
N |
O |
|||
| 3mdc | 1 | Q9UGP5 | 100.0 | 0.0 |
X-RAY |
2010-04-28 | ARG | A:235 | A:485 | 114.0 | 0.507 | -102.2 | 157.4 | 114.0 | 0.507 | 0.0 |
NA HOH |
3.047 2.719 |
NH2 O |
NA O |
|||
| 3mgh | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2010-05-19 | ARG | A:239 | A:485 | 88.0 | 0.391 | -94.3 | 156.3 | 88.0 | 0.391 | 0.0 |
HOH |
2.719 |
O |
O |
|||
| ARG | E:239 | C:485 | 97.0 | 0.431 | -82.8 | 148.7 | NA | NA | NA | ||||||||||||||
| 3mgi | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2010-05-19 | ARG | A:239 | A:485 | 126.0 | 0.56 | -98.2 | 166.3 | 126.0 | 0.56 | 0.0 |
HOH |
2.529 |
N |
O |
|||
| 3pml | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-01-26 | ARG | A:239 | A:485 | 95.0 | 0.422 | -87.8 | 159.3 | 95.0 | 0.422 | 0.0 |
HOH |
2.677 |
O |
O |
|||
| ARG | B:239 | B:485 | 73.0 | 0.324 | -106.8 | 156.2 | NA | NA | NA | ||||||||||||||
| 3pmn | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-02-02 | ARG | A:239 | A:485 | 100.0 | 0.444 | -94.3 | 158.4 | 100.0 | 0.444 | 0.0 |
MN CL HOH |
4.354 7.230 2.779 |
CA CA N |
MN CL O |
|||
| 3pnc | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2011-02-02 | ARG | A:239 | A:485 | 127.0 | 0.564 | -108.6 | 161.0 | 127.0 | 0.564 | 0.0 |
HOH |
2.799 |
O |
O |
|||
| 3upq | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2012-05-23 | ARG | A:239 | A:485 | 110.0 | 0.489 | -96.4 | 155.1 | 110.0 | 0.489 | 0.0 |
MN HOH |
4.603 2.732 |
C NH1 |
MN O |
|||
| 3uq0 | 1 | Q9UGP5 | 97.6 | 0.0 |
X-RAY |
2012-05-23 | ARG | A:239 | A:485 | 114.0 | 0.507 | -105.0 | 159.2 | 114.0 | 0.507 | 0.0 |
EDO HOH |
6.702 2.722 |
NH2 N |
O1 O |
|||
| 3uq2 | 1 | Q9UGP5 | 97.31 | 0.0 |
X-RAY |
2012-05-23 | ARG | A:239 | A:485 | 109.0 | 0.484 | -111.1 | 156.1 | 109.0 | 0.484 | 0.0 |
HOH |
2.732 |
O |
O |
|||
| 4fo6 | 1 | Q9UGP5 | 97.31 | 0.0 |
X-RAY |
2012-07-11 | ARG | A:239 | A:485 | 116.0 | 0.516 | -109.4 | 154.1 | 116.0 | 0.516 | 0.0 |
HOH |
2.915 |
O |
O |
|||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q9ugp5-f1 | 1 | Q9UGP5 | 100.0 | 0.0 | ARG | A:485 | A:485 | 88.0 | 0.391 | -96.8 | 158.4 | ||