Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 103339535 . C A CCDS7513.1:NM_001174084.1:c.1403gGt>gTt_NP_001167555.1:p.468G>V Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xq8 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:227 B:468 67.0 0.893 T 71.3 -118.9 67.0 0.893 0.0 DA
DC
DT
HOH
 7.946
5.927
7.597
3.725
 N
N
N
O
 O3'
OP1
OP1
O
GLY B:227 A:468 64.0 0.853 T 56.1 -113.8 NA NA NA
5ca7 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:227 B:468 58.0 0.773 T 58.7 -125.1 58.0 0.773 0.0 DA
DC
DT
HOH
 7.807
5.904
7.947
6.353
 N
N
N
N
 O3'
OP1
OP1
O
GLY B:227 A:468 67.0 0.893 T 70.9 -126.1 NA NA NA
5iii 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:227 A:468 65.0 0.867 T -70.0 -13.8 65.0 0.867 0.0 DC
HOH
 8.510
3.219
 C
O
 OP1
O
5iij 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:227 A:468 66.0 0.88 T -64.2 -16.2 66.0 0.88 0.0 DC
HOH
 8.447
3.502
 C
O
 OP2
O
5iik 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:227 A:468 62.0 0.827 S 121.0 -26.7 62.0 0.827 0.0 DC
DT
HOH
 8.347
9.850
2.341
 C
N
N
 OP2
OP2
O
5iil 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:227 A:468 65.0 0.867 T -66.1 31.9 65.0 0.867 0.0 DC
HOH
 8.384
2.962
 C
O
 OP1
O
5iim 1 Q9UGP5 100.0 0.0 X-RAY
 2016-09-07 GLY A:227 A:468 69.0 0.92 S 84.6 -7.1 69.0 0.92 0.0 DC
HOH
 8.188
2.739
 C
N
 OP1
O
5iin 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:227 A:468 58.0 0.773 S 97.0 -16.1 58.0 0.773 0.0 DC
DT
HOH
 8.349
9.927
4.257
 C
N
CA
 OP2
OP2
O
5iio 4 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY M:227 A:468 54.0 0.72 T 58.2 -128.0 54.0 0.72 0.0 DT
DA
DC
HOH
 6.172
4.940
8.078
2.797
 N
N
N
O
 O3'
OP1
OP1
O
GLY N:227 E:468 63.0 0.84 T 55.3 -125.6 NA NA NA
GLY O:227 I:468 61.0 0.813 T 57.9 -127.9 NA NA NA
GLY P:227 M:468 62.0 0.827 T 54.7 -128.4 NA NA NA
1xsl 4 Q9UGP5 100.0 0.0 X-RAY
 2005-01-18 GLY M:228 A:468 62.0 0.827 T 66.1 -130.5 62.0 0.827 0.0 DC
DG
DC
HOH
 5.916
5.206
7.819
2.634
 N
N
N
O
 O3'
OP1
OP1
O
GLY N:228 E:468 60.0 0.8 T 70.7 -138.3 NA NA NA
GLY O:228 I:468 65.0 0.867 T 63.5 -124.8 NA NA NA
GLY P:228 M:468 65.0 0.867 T 63.3 -130.2 NA NA NA
2bcq 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:228 A:468 56.0 0.747 T -69.2 -1.6 56.0 0.747 0.0 DC
HOH
 8.555
2.555
 C
N
 OP1
O
2bcr 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:228 A:468 65.0 0.867 T -69.1 -4.2 65.0 0.867 0.0 DC
HOH
 8.470
2.534
 C
N
 OP1
O
2bcs 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:228 A:468 54.0 0.72 T -72.1 -6.3 54.0 0.72 0.0 DC
HOH
 8.432
2.486
 C
N
 OP2
O
2bcu 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:228 A:468 58.0 0.773 T -69.8 -3.9 58.0 0.773 0.0 DC
HOH
 8.022
2.456
 C
N
 OP1
O
2bcv 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:228 A:468 54.0 0.72 T -66.6 -8.3 54.0 0.72 0.0 DC
HOH
 8.480
2.864
 C
O
 OP2
O
2gws 4 Q9UGP5 100.0 0.0 X-RAY
 2006-09-05 GLY M:228 A:468 63.0 0.84 T 70.5 -127.6 63.0 0.84 0.0 DC
DG
DC
HOH
 6.076
5.245
7.829
2.611
 N
N
N
O
 O3'
OP1
OP1
O
GLY N:228 E:468 66.0 0.88 T 60.1 -137.1 NA NA NA
GLY O:228 I:468 62.0 0.827 T 66.1 -139.1 NA NA NA
GLY P:228 M:468 62.0 0.827 T 58.8 -130.6 NA NA NA
4xrh 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:228 B:468 65.0 0.867 T 75.1 -123.1 65.0 0.867 0.0 DA
DC
DT
 7.640
5.657
7.671
 N
N
N
 O3'
OP1
OP1
GLY B:228 A:468 69.0 0.92 T 69.4 -119.7 NA NA NA
5ddm 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:228 B:468 70.0 0.933 T 58.8 -126.5 70.0 0.933 0.0 DA
DC
DT
HOH
 7.471
5.581
7.700
4.496
 N
N
N
O
 O3'
OP1
OP1
O
GLY B:228 A:468 66.0 0.88 T 57.8 -127.2 NA NA NA
5ddy 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:228 A:468 50.0 0.667 T 60.2 -111.6 50.0 0.667 0.0
GLY B:228 C:468 65.0 0.867 T 72.1 -115.6 NA NA NA
GLY C:228 E:468 40.0 0.533 T 82.8 -127.9 NA NA NA
GLY D:228 G:468 51.0 0.68 T 62.0 -122.9 NA NA NA
3c5g 1 Q9UGP5 99.7 0.0 X-RAY
 2008-07-29 GLY A:228 A:468 59.0 0.787 T -68.8 -16.4 59.0 0.787 0.0 DC
HOH
 9.375
2.852
 N
O
 OP2
O
GLY E:228 B:468 64.0 0.853 S 70.0 177.7 NA NA NA
5chg 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:227 A:468 66.0 0.88 T 56.7 -129.0 66.0 0.88 0.0 DA
DC
DT
 7.462
5.507
7.771
 N
N
N
 O3'
OP1
OP1
GLY B:227 B:468 55.0 0.733 T 54.9 -131.2 NA NA NA
5cj7 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:227 A:468 58.0 0.773 T 59.4 -123.6 58.0 0.773 0.0 DA
DC
DT
 7.659
6.048
8.064
 N
N
N
 O3'
OP1
OP1
GLY B:227 B:468 62.0 0.827 T 60.8 -120.9 NA NA NA
5cp2 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:227 A:468 63.0 0.84 T 60.1 -123.0 63.0 0.84 0.0 HOH
 3.571
 CA
 O
GLY B:227 B:468 60.0 0.8 T 62.1 -123.2 NA NA NA
5cr0 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:227 A:468 61.0 0.813 T 57.8 -131.0 61.0 0.813 0.0 DA
DC
DT
 6.944
5.620
7.482
 N
N
N
 O3'
OP1
OP1
GLY B:227 B:468 75.0 1.0 T 60.6 -127.6 NA NA NA
3c5f 4 Q9UGP5 99.7 0.0 X-RAY
 2008-09-02 GLY G:228 A:468 67.0 0.893 -98.6 26.3 67.0 0.893 0.0 DC
HOH
 7.896
2.997
 C
O
 OP1
O
GLY H:228 B:468 62.0 0.827 T 60.7 -136.2 NA NA NA
1xsn 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 GLY D:228 A:468 53.0 0.707 T -83.6 -12.4 53.0 0.707 0.0 DC
HOH
 8.398
3.207
 C
O
 OP1
O
1xsp 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 GLY D:228 A:468 54.0 0.72 T -67.3 -11.6 54.0 0.72 0.0 DC
HOH
 8.496
3.118
 C
O
 OP2
O
2pfn 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:228 A:468 56.0 0.747 T -74.1 -7.0 56.0 0.747 0.0 DC
HOH
 8.381
2.831
 C
O
 OP1
O
2pfo 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:228 A:468 58.0 0.773 T -65.3 -5.4 58.0 0.773 0.0 DC
HOH
 8.341
3.283
 C
CA
 OP2
O
2pfp 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:228 A:468 54.0 0.72 T -75.8 -7.6 54.0 0.72 0.0 DC
HOH
 8.446
2.425
 C
N
 OP2
O
2pfq 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:228 A:468 53.0 0.707 T -58.9 0.8 53.0 0.707 0.0 DC
HOH
 8.427
3.427
 C
O
 OP1
O
3hw8 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 GLY A:228 A:468 57.0 0.76 T -69.6 -13.1 57.0 0.76 0.0 DC
HOH
 8.481
2.516
 C
N
 OP1
O
3hwt 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 GLY A:228 A:468 68.0 0.907 T -78.6 -11.1 68.0 0.907 0.0 DC
HOH
 8.402
4.180
 C
CA
 OP2
O
1rzt 4 Q9UGP5 100.0 0.0 X-RAY
 2004-03-02 GLY M:224 A:468 68.0 0.907 T 64.5 -130.7 68.0 0.907 0.0 DC
DG
DC
HOH
 6.323
5.123
7.825
2.855
 N
N
N
N
 O3'
OP1
OP1
O
GLY N:224 E:468 67.0 0.893 T 65.3 -129.8 NA NA NA
GLY O:224 I:468 68.0 0.907 T 64.4 -121.9 NA NA NA
GLY P:224 M:468 66.0 0.88 T 63.9 -128.5 NA NA NA
4k4g 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 GLY A:225 A:468 51.0 0.68 T -62.7 -21.2 51.0 0.68 0.0 DC
HOH
 9.608
3.743
 C
O
 OP1
O
GLY E:225 NA:NA DO NA DO DO DO NA NA NA
GLY I:225 I:468 65.0 0.867 T 52.3 -125.0 NA NA NA
GLY M:225 M:468 68.0 0.907 T 52.3 -122.3 NA NA NA
4k4h 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 GLY A:225 A:468 57.0 0.76 T -57.9 -21.4 57.0 0.76 0.0 DC
HOH
 8.676
3.080
 C
O
 OP1
O
GLY E:225 E:468 89.0 1.0 360.0 135.4 NA NA NA
GLY I:225 I:468 69.0 0.92 T 53.5 -123.8 NA NA NA
GLY M:225 M:468 70.0 0.933 T 58.9 -124.9 NA NA NA
4k4i 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 GLY A:225 A:468 56.0 0.747 T -63.5 -21.0 56.0 0.747 0.0 DC
HOH
 8.751
3.047
 C
O
 OP1
O
GLY E:225 E:468 44.0 0.587 S 81.9 42.4 NA NA NA
GLY I:225 I:468 66.0 0.88 T 50.2 -126.1 NA NA NA
GLY M:225 M:468 69.0 0.92 T 52.6 -121.1 NA NA NA
3hx0 1 Q9UGP5 98.8 0.0 X-RAY
 2009-08-25 GLY A:228 A:468 63.0 0.84 S -89.7 -2.4 63.0 0.84 0.0 DC
 8.451
 C
 OP2
GLY E:228 F:468 78.0 1.0 T -85.6 16.6 NA NA NA
GLY I:228 K:468 66.0 0.88 T 69.9 -134.1 NA NA NA
GLY M:228 P:468 59.0 0.787 T 52.1 -128.1 NA NA NA
5dkw 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:220 A:468 57.0 0.76 T 64.5 -121.3 57.0 0.76 0.0 DT
DA
DC
HOH
 5.972
4.721
8.120
3.718
 N
N
N
CA
 O3'
OP1
OP1
O
GLY B:220 B:468 55.0 0.733 T 62.7 -121.1 NA NA NA
5cb1 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:219 A:468 58.0 0.773 T 70.0 -113.2 58.0 0.773 0.0
GLY B:219 B:468 54.0 0.72 T 66.4 -114.2 NA NA NA
4x5v 1 Q9UGP5 100.0 0.0 X-RAY
 2015-10-28 GLY A:218 A:468 61.0 0.813 S 126.6 -69.4 61.0 0.813 0.0 DA
DC
HOH
 9.977
8.120
4.058
 O
O
O
 O3'
OP1
O
4xa5 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-10 GLY A:218 A:468 74.0 0.987 T -45.6 -26.7 74.0 0.987 0.0 DC
ACT
GOL
HOH
 8.530
3.149
7.536
4.807
 C
O
O
N
 OP1
OXT
O1
O
4xus 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-03 GLY A:218 A:468 71.0 0.947 T -72.6 -15.2 71.0 0.947 0.0 DC
HOH
 8.497
3.799
 C
O
 OP2
O
5cwr 1 Q9UGP5 99.69 0.0 X-RAY
 2016-02-24 GLY A:219 A:468 96.0 1.0 -85.1 360.0 96.0 1.0 0.0 DC
HOH
 9.042
8.725
 N
O
 OP1
O
GLY D:219 B:468 105.0 1.0 360.0 -162.2 NA NA NA
3mda 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 GLY A:218 A:468 49.0 0.653 T -70.2 -8.1 49.0 0.653 0.0 DC
HOH
 8.405
3.225
 C
O
 OP2
O
3mdc 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 GLY A:218 A:468 58.0 0.773 T -64.5 -11.2 58.0 0.773 0.0 DC
HOH
 8.565
2.606
 C
O
 OP2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugp5-f1 1 Q9UGP5 100.0 0.0 GLY A:468 A:468 59.0 0.787 T 75.8 -143.7