Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 103342588 . C A CCDS7513.1:NM_001174084.1:c.1126Ggc>Tgc_NP_001167555.1:p.376G>C Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xq8 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:135 B:376 1.0 0.013 H -64.2 -33.7 1.0 0.013 0.0 DT
HOH
 8.378
3.104
 CA
O
 OP1
O
GLY B:135 A:376 0.0 0.0 H -64.2 -44.1 NA NA NA
5ca7 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:135 B:376 1.0 0.013 H -66.5 -36.4 1.0 0.013 0.0 DT
HOH
 8.429
2.892
 CA
O
 OP1
O
GLY B:135 A:376 1.0 0.013 H -59.4 -40.9 NA NA NA
5iii 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:135 A:376 1.0 0.013 H -57.2 -43.4 1.0 0.013 0.0 DT
DA
NA
HOH
 9.722
8.162
7.969
2.751
 CA
CA
CA
O
 O3'
OP1
NA
O
5iij 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:135 A:376 1.0 0.013 H -57.2 -41.3 1.0 0.013 0.0 DT
DA
NA
HOH
 9.721
8.172
7.962
2.704
 CA
CA
CA
O
 O3'
OP1
NA
O
5iik 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:135 A:376 1.0 0.013 H -60.5 -42.2 1.0 0.013 0.0 DT
DA
NA
HOH
 9.839
8.227
8.129
2.713
 CA
CA
CA
O
 O3'
OP1
NA
O
5iil 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:135 A:376 1.0 0.013 H -58.3 -46.1 1.0 0.013 0.0 DT
DA
NA
HOH
 9.811
8.235
8.071
2.761
 CA
CA
CA
O
 O3'
OP1
NA
O
5iim 1 Q9UGP5 100.0 0.0 X-RAY
 2016-09-07 GLY A:135 A:376 1.0 0.013 H -55.3 -40.2 1.0 0.013 0.0 DT
DA
NA
HOH
 9.804
8.224
8.014
2.734
 CA
CA
CA
O
 O3'
OP1
NA
O
5iin 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY A:135 A:376 1.0 0.013 H -61.5 -38.0 1.0 0.013 0.0 DT
DA
NA
HOH
 9.825
8.225
8.136
2.826
 CA
CA
CA
O
 O3'
OP1
NA
O
5iio 4 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 GLY M:135 A:376 1.0 0.013 H -64.6 -35.3 1.0 0.013 0.0 DT
DA
NA
HOH
 9.938
8.361
8.190
2.709
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY N:135 E:376 1.0 0.013 H -60.3 -45.4 NA NA NA
GLY O:135 I:376 1.0 0.013 H -54.8 -45.5 NA NA NA
GLY P:135 M:376 1.0 0.013 H -56.7 -39.7 NA NA NA
1xsl 4 Q9UGP5 100.0 0.0 X-RAY
 2005-01-18 GLY M:136 A:376 1.0 0.013 H -60.2 -37.2 1.0 0.013 0.0 DC
DG
NA
HOH
 9.948
8.460
8.447
2.857
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY N:136 E:376 1.0 0.013 H -68.2 -42.9 NA NA NA
GLY O:136 I:376 1.0 0.013 H -59.8 -37.8 NA NA NA
GLY P:136 M:376 1.0 0.013 H -61.8 -36.3 NA NA NA
2bcq 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:136 A:376 1.0 0.013 H -61.9 -40.5 1.0 0.013 0.0 DT
DA
NA
HOH
 9.768
8.145
8.004
2.720
 CA
CA
CA
O
 O3'
OP1
NA
O
2bcr 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:136 A:376 0.0 0.0 H -58.2 -45.4 0.0 0.0 0.0 DT
DA
NA
HOH
 9.759
8.183
7.986
2.788
 CA
CA
CA
O
 O3'
OP1
NA
O
2bcs 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:136 A:376 1.0 0.013 H -58.4 -41.7 1.0 0.013 0.0 DT
DA
NA
HOH
 9.773
8.202
8.007
2.712
 CA
CA
CA
O
 O3'
OP1
NA
O
2bcu 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:136 A:376 1.0 0.013 H -61.6 -42.4 1.0 0.013 0.0 DT
DT
NA
HOH
 9.930
8.315
8.094
2.737
 CA
CA
CA
O
 O3'
OP1
NA
O
2bcv 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 GLY D:136 A:376 0.0 0.0 H -62.3 -39.6 0.0 0.0 0.0 DT
DA
NA
HOH
 9.868
8.298
8.096
2.784
 CA
CA
CA
O
 O3'
OP1
NA
O
2gws 4 Q9UGP5 100.0 0.0 X-RAY
 2006-09-05 GLY M:136 A:376 1.0 0.013 H -62.7 -36.5 1.0 0.013 0.0 DC
DG
NA
HOH
 9.946
8.451
8.478
2.751
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY N:136 E:376 1.0 0.013 H -62.2 -40.0 NA NA NA
GLY O:136 I:376 0.0 0.0 H -64.8 -31.2 NA NA NA
GLY P:136 M:376 1.0 0.013 H -61.0 -38.1 NA NA NA
4xrh 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:136 B:376 1.0 0.013 H -63.0 -35.9 1.0 0.013 0.0 DT
 8.420
 CA
 OP1
GLY B:136 A:376 0.0 0.0 H -59.6 -39.4 NA NA NA
5ddm 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:136 B:376 1.0 0.013 H -58.4 -31.9 1.0 0.013 0.0 DT
NA
HOH
 8.273
8.457
4.377
 CA
CA
O
 OP1
NA
O
GLY B:136 A:376 0.0 0.0 H -68.5 -25.8 NA NA NA
5ddy 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:136 A:376 0.0 0.0 H -62.2 -39.5 0.0 0.0 0.0 MN
HOH
 9.095
9.779
 CA
CA
 MN
O
GLY B:136 C:376 0.0 0.0 T -78.3 4.2 NA NA NA
GLY C:136 E:376 1.0 0.013 H -63.0 -33.2 NA NA NA
GLY D:136 G:376 1.0 0.013 H -77.4 -13.0 NA NA NA
3c5g 1 Q9UGP5 99.7 0.0 X-RAY
 2008-07-29 GLY A:136 A:376 1.0 0.013 H -63.6 -36.7 1.0 0.013 0.0 DT
DA
NA
HOH
 9.610
8.135
7.961
2.753
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY E:136 B:376 1.0 0.013 H -64.0 -40.3 NA NA NA
5chg 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:135 A:376 1.0 0.013 H -61.8 -27.8 1.0 0.013 0.0 DT
MG
HOH
 8.407
8.619
2.629
 CA
CA
O
 OP1
MG
O
GLY B:135 B:376 0.0 0.0 H -63.8 -37.4 NA NA NA
5cj7 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:135 A:376 0.0 0.0 H -72.8 -28.2 0.0 0.0 0.0 DT
DA
HOH
 8.470
9.939
6.535
 CA
CA
O
 OP1
OP1
O
GLY B:135 B:376 0.0 0.0 H -58.9 -38.7 NA NA NA
5cp2 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:135 A:376 1.0 0.013 H -62.3 -36.2 1.0 0.013 0.0 HOH
 8.536
 N
 O
GLY B:135 B:376 1.0 0.013 H -58.7 -38.0 NA NA NA
5cr0 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 GLY A:135 A:376 2.0 0.027 H -66.0 -26.1 2.0 0.027 0.0 DT
HOH
 8.537
8.610
 CA
CA
 OP1
O
GLY B:135 B:376 0.0 0.0 H -63.3 -35.4 NA NA NA
3c5f 4 Q9UGP5 99.7 0.0 X-RAY
 2008-09-02 GLY G:136 A:376 1.0 0.013 H -59.5 -41.8 1.0 0.013 0.0 DT
DA
NA
HOH
 9.674
8.107
8.026
2.753
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY H:136 B:376 1.0 0.013 H -63.7 -33.3 NA NA NA
1xsn 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 GLY D:136 A:376 1.0 0.013 H -61.6 -42.1 1.0 0.013 0.0 DT
DA
NA
HOH
 9.807
8.241
8.096
2.751
 CA
CA
CA
O
 O3'
OP1
NA
O
1xsp 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 GLY D:136 A:376 0.0 0.0 H -66.0 -38.8 0.0 0.0 0.0 DT
DA
NA
HOH
 9.931
8.319
8.157
2.639
 CA
CA
CA
O
 O3'
OP1
NA
O
2pfn 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:136 A:376 0.0 0.0 H -60.7 -39.1 0.0 0.0 0.0 DT
DA
NA
NA
HOH
 9.717
8.141
8.974
7.957
2.737
 CA
CA
CA
CA
O
 O3'
OP1
NA
NA
O
2pfo 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:136 A:376 1.0 0.013 H -60.0 -40.5 1.0 0.013 0.0 DT
DA
NA
HOH
 9.895
8.306
8.187
2.702
 CA
CA
CA
O
 O3'
OP1
NA
O
2pfp 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:136 A:376 0.0 0.0 H -65.4 -37.0 0.0 0.0 0.0 DT
DA
NA
HOH
 9.870
8.274
8.147
2.702
 CA
CA
CA
O
 O3'
OP1
NA
O
2pfq 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 GLY D:136 A:376 1.0 0.013 H -60.2 -44.8 1.0 0.013 0.0 DA
NA
HOH
 8.364
8.154
2.964
 CA
CA
O
 OP1
NA
O
3hw8 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 GLY A:136 A:376 1.0 0.013 H -61.8 -43.2 1.0 0.013 0.0 DT
DA
NA
HOH
 9.728
8.202
7.930
2.851
 CA
CA
CA
O
 O3'
OP1
NA
O
3hwt 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 GLY A:136 A:376 1.0 0.013 H -58.7 -43.9 1.0 0.013 0.0 DT
DA
NA
HOH
 9.798
8.265
8.031
2.706
 CA
CA
CA
O
 O3'
OP1
NA
O
1rzt 4 Q9UGP5 100.0 0.0 X-RAY
 2004-03-02 GLY M:132 A:376 1.0 0.013 H -62.0 -37.9 1.0 0.013 0.0 DC
DG
NA
HOH
 9.956
8.382
8.338
2.744
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY N:132 E:376 0.0 0.0 H -79.4 -39.7 NA NA NA
GLY O:132 I:376 1.0 0.013 H -64.4 -30.4 NA NA NA
GLY P:132 M:376 1.0 0.013 H -62.1 -36.7 NA NA NA
4k4g 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 GLY A:133 A:376 1.0 0.013 H -61.7 -40.5 1.0 0.013 0.0 DT
DA
CA
HOH
 9.684
8.244
8.024
2.796
 CA
CA
CA
O
 O3'
OP1
CA
O
GLY E:133 E:376 1.0 0.013 H -57.3 -39.2 NA NA NA
GLY I:133 I:376 1.0 0.013 H -51.7 -43.2 NA NA NA
GLY M:133 M:376 0.0 0.0 H -60.7 -45.5 NA NA NA
4k4h 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 GLY A:133 A:376 1.0 0.013 H -54.9 -44.1 1.0 0.013 0.0 DT
DA
CA
HOH
 9.619
8.133
8.018
2.673
 CA
CA
CA
O
 O3'
OP1
CA
O
GLY E:133 E:376 0.0 0.0 H -67.3 -31.3 NA NA NA
GLY I:133 I:376 1.0 0.013 H -44.6 -46.2 NA NA NA
GLY M:133 M:376 1.0 0.013 H -55.3 -41.2 NA NA NA
4k4i 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 GLY A:133 A:376 0.0 0.0 H -66.3 -38.9 0.0 0.0 0.0 DT
DA
CA
HOH
 9.718
8.291
8.057
2.863
 CA
CA
CA
O
 O3'
OP1
CA
O
GLY E:133 E:376 0.0 0.0 H -64.7 -36.4 NA NA NA
GLY I:133 I:376 1.0 0.013 H -56.9 -37.4 NA NA NA
GLY M:133 M:376 1.0 0.013 H -59.7 -44.2 NA NA NA
3hx0 1 Q9UGP5 98.8 0.0 X-RAY
 2009-08-25 GLY A:136 A:376 1.0 0.013 H -60.1 -32.6 1.0 0.013 0.0 DT
DA
 9.874
8.308
 CA
CA
 O3'
OP1
GLY E:136 F:376 0.0 0.0 H -58.7 -36.6 NA NA NA
GLY I:136 K:376 1.0 0.013 H -54.5 -30.0 NA NA NA
GLY M:136 P:376 1.0 0.013 H -64.6 -53.7 NA NA NA
5dkw 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:128 A:376 1.0 0.013 H -59.0 -44.2 1.0 0.013 0.0 DT
DA
HOH
 9.898
8.408
2.898
 CA
CA
O
 O3'
OP1
O
GLY B:128 B:376 1.0 0.013 H -56.1 -42.6 NA NA NA
5cb1 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 GLY A:127 A:376 0.0 0.0 H -58.4 -44.1 0.0 0.0 0.0
GLY B:127 B:376 0.0 0.0 H -57.6 -37.6 NA NA NA
4x5v 1 Q9UGP5 100.0 0.0 X-RAY
 2015-10-28 GLY A:126 A:376 0.0 0.0 H -61.2 -41.9 0.0 0.0 0.0 DT
DA
DC
MG
HOH
 9.792
8.212
9.905
8.032
2.798
 CA
CA
CA
CA
O
 O3'
OP1
OP1
MG
O
4xa5 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-10 GLY A:126 A:376 1.0 0.013 H -58.9 -39.6 1.0 0.013 0.0 DT
DA
MG
HOH
 9.807
8.195
7.980
2.675
 CA
CA
CA
O
 O3'
OP1
MG
O
4xus 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-03 GLY A:126 A:376 0.0 0.0 H -57.9 -46.4 0.0 0.0 0.0 DT
DA
MG
HOH
 9.899
8.243
8.208
2.738
 CA
CA
CA
O
 O3'
OP1
MG
O
5cwr 1 Q9UGP5 99.69 0.0 X-RAY
 2016-02-24 GLY A:127 A:376 1.0 0.013 H -67.5 -35.4 1.0 0.013 0.0 DT
DA
HOH
 9.777
8.181
2.920
 CA
CA
O
 O3'
OP1
O
GLY D:127 B:376 1.0 0.013 H -65.9 -39.7 NA NA NA
3mda 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 GLY A:126 A:376 1.0 0.013 H -55.4 -44.6 1.0 0.013 0.0 DT
DA
NA
HOH
 9.819
8.207
8.029
2.653
 CA
CA
CA
O
 O3'
OP1
NA
O
3mdc 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 GLY A:126 A:376 1.0 0.013 H -55.6 -46.2 1.0 0.013 0.0 DT
DA
NA
HOH
 9.837
8.229
7.920
2.683
 CA
CA
CA
O
 O3'
OP1
NA
O
3mgh 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 GLY A:135 A:376 1.0 0.013 H -62.5 -44.2 1.0 0.013 0.0 DT
DA
NA
HOH
 9.769
8.183
7.979
3.034
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY E:135 C:376 1.0 0.013 H -56.9 -46.2 NA NA NA
3mgi 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 GLY A:135 A:376 0.0 0.0 H -63.3 -52.6 0.0 0.0 0.0 DT
DA
NA
HOH
 9.913
8.259
8.273
3.242
 CA
CA
CA
O
 O3'
OP1
NA
O
3pml 1 Q9UGP5 97.6 0.0 X-RAY
 2011-01-26 GLY A:135 A:376 1.0 0.013 H -59.6 -36.3 1.0 0.013 0.0 DT
DA
NA
HOH
 9.621
8.175
8.191
2.736
 CA
CA
CA
O
 O3'
OP1
NA
O
GLY B:135 B:376 0.0 0.0 H -67.7 -43.8 NA NA NA
3pmn 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 GLY A:135 A:376 1.0 0.013 H -63.7 -40.4 1.0 0.013 0.0 DT
DA
NA
MN
HOH
 9.857
8.278
8.092
9.808
2.837
 CA
CA
CA
O
O
 O3'
OP1
NA
MN
O
3pnc 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 GLY A:135 A:376 1.0 0.013 H -61.7 -40.8 1.0 0.013 0.0 DT
DA
NA
TRS
HOH
 9.815
8.244
8.040
8.969
2.893
 CA
CA
CA
CA
O
 O3'
OP1
NA
O3
O
3upq 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 GLY A:135 A:376 1.0 0.013 H -55.9 -41.0 1.0 0.013 0.0 DT
DA
MN
NA
HOH
 9.819
8.197
9.566
7.953
2.671
 CA
CA
O
CA
O
 O3'
OP1
MN
NA
O
3uq0 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 GLY A:135 A:376 0.0 0.0 H -58.6 -37.0 0.0 0.0 0.0 DT
DA
NA
HOH
 9.780
8.092
7.928
2.508
 CA
CA
CA
O
 O3'
OP1
NA
O
3uq2 1 Q9UGP5 97.31 0.0 X-RAY
 2012-05-23 GLY A:135 A:376 0.0 0.0 H -63.5 -39.8 0.0 0.0 0.0 DT
DA
NA
HOH
 9.808
8.178
8.042
2.657
 CA
CA
CA
O
 O3'
OP1
NA
O
4fo6 1 Q9UGP5 97.31 0.0 X-RAY
 2012-07-11 GLY A:135 A:376 0.0 0.0 H -53.7 -42.7 0.0 0.0 0.0 DT
DA
NA
HOH
 9.796
8.202
8.047
2.705
 CA
CA
CA
O
 O3'
OP1
NA
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugp5-f1 1 Q9UGP5 100.0 0.0 GLY A:376 A:376 0.0 0.0 H -59.4 -34.0