Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 103342594 . C A CCDS7513.1:NM_001174084.1:c.1120Gcc>Tcc_NP_001167555.1:p.374A>S Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xq8 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:133 B:374 43.0 0.374 H -61.1 -43.6 43.0 0.374 0.0 DG
HOH
 8.803
2.944
 N
O
 O3'
O
ALA B:133 A:374 46.0 0.4 H -44.7 -57.4 NA NA NA
5ca7 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:133 B:374 41.0 0.357 H -62.8 -38.5 41.0 0.357 0.0 DG
HOH
 8.798
2.548
 N
O
 O3'
O
ALA B:133 A:374 45.0 0.391 H -60.5 -45.9 NA NA NA
5iii 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:133 A:374 45.0 0.391 H -62.2 -35.1 45.0 0.391 0.0 DG
HOH
 9.412
2.747
 N
O
 OP1
O
5iij 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:133 A:374 44.0 0.383 H -64.4 -36.7 44.0 0.383 0.0 DG
HOH
 9.314
2.773
 N
O
 OP1
O
5iik 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:133 A:374 43.0 0.374 H -59.8 -39.1 43.0 0.374 0.0 DG
HOH
 9.316
2.738
 N
O
 OP1
O
5iil 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:133 A:374 44.0 0.383 H -63.5 -38.4 44.0 0.383 0.0 DG
HOH
 9.089
2.732
 N
O
 OP1
O
5iim 1 Q9UGP5 100.0 0.0 X-RAY
 2016-09-07 ALA A:133 A:374 44.0 0.383 H -64.9 -36.2 44.0 0.383 0.0 DG
HOH
 9.138
2.725
 N
O
 OP1
O
5iin 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:133 A:374 44.0 0.383 H -61.8 -38.3 44.0 0.383 0.0 DG
HOH
 9.371
2.849
 N
O
 OP1
O
5iio 4 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA M:133 A:374 42.0 0.365 H -66.6 -38.5 42.0 0.365 0.0 HOH
 2.651
 O
 O
ALA N:133 E:374 43.0 0.374 H -62.2 -43.4 NA NA NA
ALA O:133 I:374 43.0 0.374 H -58.3 -48.2 NA NA NA
ALA P:133 M:374 42.0 0.365 H -63.4 -40.0 NA NA NA
1xsl 4 Q9UGP5 100.0 0.0 X-RAY
 2005-01-18 ALA M:134 A:374 42.0 0.365 H -61.2 -45.1 42.0 0.365 0.0 DA
DC
HOH
 9.290
8.103
3.043
 N
N
O
 O3'
OP1
O
ALA N:134 E:374 42.0 0.365 H -56.3 -44.3 NA NA NA
ALA O:134 I:374 42.0 0.365 H -60.1 -51.8 NA NA NA
ALA P:134 M:374 42.0 0.365 H -65.5 -39.1 NA NA NA
2bcq 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:134 A:374 47.0 0.409 H -65.8 -37.7 47.0 0.409 0.0 DG
HOH
 9.285
2.843
 N
O
 OP1
O
2bcr 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:134 A:374 47.0 0.409 H -64.3 -38.7 47.0 0.409 0.0 DG
HOH
 9.242
2.768
 N
O
 OP1
O
2bcs 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:134 A:374 44.0 0.383 H -62.8 -41.2 44.0 0.383 0.0 DG
HOH
 9.222
2.888
 N
O
 OP1
O
2bcu 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:134 A:374 45.0 0.391 H -62.5 -36.0 45.0 0.391 0.0 DG
HOH
 9.425
2.939
 N
O
 OP1
O
2bcv 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:134 A:374 46.0 0.4 H -64.6 -38.3 46.0 0.4 0.0 DG
HOH
 9.006
2.800
 N
O
 OP1
O
2gws 4 Q9UGP5 100.0 0.0 X-RAY
 2006-09-05 ALA M:134 A:374 44.0 0.383 H -61.2 -43.5 44.0 0.383 0.0 DA
DC
HOH
 9.308
8.094
2.948
 N
N
O
 O3'
OP1
O
ALA N:134 E:374 45.0 0.391 H -54.4 -39.3 NA NA NA
ALA O:134 I:374 48.0 0.417 H -58.0 -45.0 NA NA NA
ALA P:134 M:374 45.0 0.391 H -62.2 -41.0 NA NA NA
4xrh 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:134 B:374 44.0 0.383 H -65.8 -35.5 44.0 0.383 0.0 DG
 8.586
 N
 O3'
ALA B:134 A:374 46.0 0.4 H -66.5 -49.7 NA NA NA
5ddm 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:134 B:374 43.0 0.374 H -65.2 -35.7 43.0 0.374 0.0 DG
HOH
 8.845
7.675
 N
CB
 O3'
O
ALA B:134 A:374 47.0 0.409 H -55.9 -46.8 NA NA NA
5ddy 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:134 A:374 45.0 0.391 H -64.5 -42.1 45.0 0.391 0.0
ALA B:134 C:374 42.0 0.365 H -71.5 -36.7 NA NA NA
ALA C:134 E:374 43.0 0.374 H -66.0 -41.7 NA NA NA
ALA D:134 G:374 43.0 0.374 H -69.5 -49.4 NA NA NA
3c5g 1 Q9UGP5 99.7 0.0 X-RAY
 2008-07-29 ALA A:134 A:374 44.0 0.383 H -61.3 -37.7 44.0 0.383 0.0 DG
HOH
 9.438
2.594
 N
O
 OP1
O
ALA E:134 B:374 46.0 0.4 H -65.5 -36.8 NA NA NA
5chg 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:133 A:374 42.0 0.365 H -65.9 -42.0 42.0 0.365 0.0 DG
HOH
 8.759
4.141
 N
CB
 O3'
O
ALA B:133 B:374 46.0 0.4 H -60.4 -46.9 NA NA NA
5cj7 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:133 A:374 42.0 0.365 H -70.4 -38.6 42.0 0.365 0.0 DG
HOH
 8.795
9.167
 N
O
 O3'
O
ALA B:133 B:374 47.0 0.409 H -54.1 -48.5 NA NA NA
5cp2 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:133 A:374 46.0 0.4 H -60.7 -46.3 46.0 0.4 0.0 HOH
 7.237
 N
 O
ALA B:133 B:374 44.0 0.383 H -64.6 -41.7 NA NA NA
5cr0 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:133 A:374 42.0 0.365 H -68.7 -39.5 42.0 0.365 0.0 DG
 8.801
 N
 O3'
ALA B:133 B:374 47.0 0.409 H -61.5 -48.4 NA NA NA
3c5f 4 Q9UGP5 99.7 0.0 X-RAY
 2008-09-02 ALA G:134 A:374 45.0 0.391 H -59.1 -38.7 45.0 0.391 0.0 DG
HOH
 9.841
2.772
 N
O
 OP1
O
ALA H:134 B:374 44.0 0.383 H -64.5 -38.2 NA NA NA
1xsn 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ALA D:134 A:374 48.0 0.417 H -65.7 -36.3 48.0 0.417 0.0 DG
HOH
 9.261
2.888
 N
O
 OP1
O
1xsp 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ALA D:134 A:374 48.0 0.417 H -63.3 -37.5 48.0 0.417 0.0 DG
HOH
 9.364
2.609
 N
O
 OP1
O
2pfn 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:134 A:374 46.0 0.4 H -62.4 -39.9 46.0 0.4 0.0 DG
HOH
 9.078
2.988
 N
O
 OP1
O
2pfo 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:134 A:374 46.0 0.4 H -62.0 -37.6 46.0 0.4 0.0 DG
HOH
 9.584
2.771
 N
O
 OP1
O
2pfp 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:134 A:374 47.0 0.409 H -66.3 -38.1 47.0 0.409 0.0 DG
HOH
 9.225
2.786
 N
O
 OP1
O
2pfq 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:134 A:374 48.0 0.417 H -62.8 -38.4 48.0 0.417 0.0 DG
HOH
 9.283
2.982
 N
O
 OP1
O
3hw8 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ALA A:134 A:374 46.0 0.4 H -64.7 -39.4 46.0 0.4 0.0 DG
HOH
 9.430
2.857
 N
O
 OP1
O
3hwt 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ALA A:134 A:374 47.0 0.409 H -69.1 -33.9 47.0 0.409 0.0 DG
HOH
 9.215
2.751
 N
O
 OP1
O
1rzt 4 Q9UGP5 100.0 0.0 X-RAY
 2004-03-02 ALA M:130 A:374 42.0 0.365 H -62.6 -40.6 42.0 0.365 0.0 DA
DC
HOH
 9.520
8.182
2.849
 N
N
O
 O3'
OP1
O
ALA N:130 E:374 43.0 0.374 H -67.0 -41.0 NA NA NA
ALA O:130 I:374 42.0 0.365 H -60.2 -44.3 NA NA NA
ALA P:130 M:374 42.0 0.365 H -63.1 -32.8 NA NA NA
4k4g 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ALA A:131 A:374 42.0 0.365 H -62.6 -39.3 42.0 0.365 0.0 DG
HOH
 9.190
2.648
 N
O
 OP1
O
ALA E:131 E:374 46.0 0.4 H -63.1 -40.4 NA NA NA
ALA I:131 I:374 43.0 0.374 H -66.6 -35.6 NA NA NA
ALA M:131 M:374 42.0 0.365 H -61.5 -41.3 NA NA NA
4k4h 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ALA A:131 A:374 41.0 0.357 H -60.6 -42.0 41.0 0.357 0.0 DG
HOH
 9.205
2.727
 N
O
 OP1
O
ALA E:131 E:374 44.0 0.383 H -63.7 -40.4 NA NA NA
ALA I:131 I:374 42.0 0.365 H -67.6 -34.7 NA NA NA
ALA M:131 M:374 43.0 0.374 H -58.0 -40.1 NA NA NA
4k4i 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ALA A:131 A:374 42.0 0.365 H -56.9 -43.5 42.0 0.365 0.0 DG
HOH
 9.123
2.758
 N
O
 OP1
O
ALA E:131 E:374 44.0 0.383 H -53.8 -45.4 NA NA NA
ALA I:131 I:374 42.0 0.365 H -63.0 -38.6 NA NA NA
ALA M:131 M:374 38.0 0.33 H -63.7 -46.9 NA NA NA
3hx0 1 Q9UGP5 98.8 0.0 X-RAY
 2009-08-25 ALA A:134 A:374 44.0 0.383 H -61.1 -38.9 44.0 0.383 0.0 DG
HOH
 9.403
8.280
 N
CB
 OP1
O
ALA E:134 F:374 45.0 0.391 H -60.8 -42.5 NA NA NA
ALA I:134 K:374 42.0 0.365 H -55.7 -44.7 NA NA NA
ALA M:134 P:374 42.0 0.365 H -64.0 -45.2 NA NA NA
5dkw 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:126 A:374 44.0 0.383 H -65.5 -35.2 44.0 0.383 0.0 DT
DG
HOH
 9.754
8.547
3.408
 N
N
CB
 O3'
OP1
O
ALA B:126 B:374 47.0 0.409 H -63.3 -40.9 NA NA NA
5cb1 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:125 A:374 44.0 0.383 H -65.8 -35.5 44.0 0.383 0.0
ALA B:125 B:374 42.0 0.365 H -60.1 -42.8 NA NA NA
4x5v 1 Q9UGP5 100.0 0.0 X-RAY
 2015-10-28 ALA A:124 A:374 45.0 0.391 H -61.9 -40.8 45.0 0.391 0.0 DG
HOH
 8.787
2.887
 N
O
 OP1
O
4xa5 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-10 ALA A:124 A:374 45.0 0.391 H -62.5 -36.1 45.0 0.391 0.0 DG
HOH
 9.139
2.842
 N
O
 OP1
O
4xus 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-03 ALA A:124 A:374 42.0 0.365 H -65.1 -35.5 42.0 0.365 0.0 DG
HOH
 9.511
2.716
 N
O
 OP1
O
5cwr 1 Q9UGP5 99.69 0.0 X-RAY
 2016-02-24 ALA A:125 A:374 45.0 0.391 H -67.1 -40.4 45.0 0.391 0.0 DG
HOH
 9.214
3.723
 N
CB
 OP1
O
ALA D:125 B:374 45.0 0.391 H -65.6 -39.4 NA NA NA
3mda 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ALA A:124 A:374 47.0 0.409 H -62.1 -38.5 47.0 0.409 0.0 DG
HOH
 9.245
2.739
 N
O
 OP1
O
3mdc 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ALA A:124 A:374 45.0 0.391 H -63.2 -39.6 45.0 0.391 0.0 DG
HOH
 9.250
3.270
 N
CB
 OP1
O
3mgh 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ALA A:133 A:374 39.0 0.339 H -65.0 -42.5 39.0 0.339 0.0 DG
HOH
 8.761
3.338
 N
CB
 OP1
O
ALA E:133 C:374 42.0 0.365 H -67.0 -40.5 NA NA NA
3mgi 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ALA A:133 A:374 46.0 0.4 H -59.3 -40.5 46.0 0.4 0.0 DG
HOH
 9.960
3.641
 N
CB
 OP1
O
3pml 1 Q9UGP5 97.6 0.0 X-RAY
 2011-01-26 ALA A:133 A:374 41.0 0.357 H -62.9 -40.9 41.0 0.357 0.0 DG
HOH
 8.849
3.518
 N
CB
 OP1
O
ALA B:133 B:374 45.0 0.391 H -60.7 -40.9 NA NA NA
3pmn 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ALA A:133 A:374 46.0 0.4 H -63.5 -40.1 46.0 0.4 0.0 DG
HOH
 9.341
2.917
 N
O
 OP1
O
3pnc 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ALA A:133 A:374 44.0 0.383 H -63.3 -41.1 44.0 0.383 0.0 DG
HOH
 9.566
2.808
 N
O
 OP1
O
3upq 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ALA A:133 A:374 47.0 0.409 H -63.0 -38.6 47.0 0.409 0.0 DG
HOH
 9.068
2.731
 N
O
 OP1
O
3uq0 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ALA A:133 A:374 47.0 0.409 H -63.9 -41.1 47.0 0.409 0.0 DG
HOH
 8.971
2.818
 N
O
 OP1
O
3uq2 1 Q9UGP5 97.31 0.0 X-RAY
 2012-05-23 ALA A:133 A:374 44.0 0.383 H -66.4 -42.7 44.0 0.383 0.0 DG
HOH
 9.395
3.988
 N
CB
 OP1
O
4fo6 1 Q9UGP5 97.31 0.0 X-RAY
 2012-07-11 ALA A:133 A:374 44.0 0.383 H -67.0 -39.5 44.0 0.383 0.0 DG
HOH
 9.647
2.906
 N
O
 OP1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugp5-f1 1 Q9UGP5 100.0 0.0 ALA A:374 A:374 47.0 0.409 H -62.2 -44.3