Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 103343285 . C A CCDS7513.1:NM_001174084.1:c.1045Gcc>Tcc_NP_001167555.1:p.349A>S Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xq8 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:108 B:349 0.0 0.0 H -68.9 -42.0 0.0 0.0 0.0 DA
DG
DT
HOH
 6.855
4.755
9.676
5.437
 N
N
N
O
 O3'
OP1
OP2
O
ALA B:108 A:349 0.0 0.0 H -64.2 -37.9 NA NA NA
5ca7 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:108 B:349 0.0 0.0 H -61.7 -40.9 0.0 0.0 0.0 DA
DG
DT
HOH
 7.025
4.804
9.608
5.432
 N
N
N
O
 O3'
OP1
OP2
O
ALA B:108 A:349 0.0 0.0 H -71.9 -26.6 NA NA NA
5iii 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:108 A:349 0.0 0.0 H -58.6 -43.8 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.850
4.699
9.284
7.944
5.388
 N
N
CB
CB
O
 O3'
OP1
OP2
NA
O
5iij 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:108 A:349 0.0 0.0 H -59.5 -44.3 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.844
4.736
9.334
7.917
5.320
 N
N
CB
CB
O
 O3'
OP1
OP2
NA
O
5iik 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:108 A:349 0.0 0.0 H -58.8 -43.3 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.884
4.691
9.339
7.837
5.366
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
5iil 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:108 A:349 0.0 0.0 H -59.8 -44.9 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.925
4.746
9.235
7.836
5.313
 N
N
CB
CB
O
 O3'
OP1
OP2
NA
O
5iim 1 Q9UGP5 100.0 0.0 X-RAY
 2016-09-07 ALA A:108 A:349 0.0 0.0 H -57.3 -41.8 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.996
4.825
9.112
7.909
5.343
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
5iin 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA A:108 A:349 0.0 0.0 H -61.1 -44.2 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.942
4.819
9.182
7.871
5.377
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
5iio 4 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ALA M:108 A:349 0.0 0.0 H -64.3 -45.9 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.804
4.748
9.131
7.815
6.140
 N
N
N
CB
N
 O3'
OP1
OP2
NA
O
ALA N:108 E:349 0.0 0.0 H -55.0 -46.5 NA NA NA
ALA O:108 I:349 0.0 0.0 H -57.7 -42.0 NA NA NA
ALA P:108 M:349 0.0 0.0 H -59.5 -44.7 NA NA NA
1xsl 4 Q9UGP5 100.0 0.0 X-RAY
 2005-01-18 ALA M:109 A:349 0.0 0.0 H -57.8 -49.2 0.0 0.0 0.0 DG
DC
DG
NA
HOH
 6.761
4.609
9.140
7.909
6.707
 N
N
N
CB
N
 O3'
OP1
OP2
NA
O
ALA N:109 E:349 0.0 0.0 H -59.7 -44.1 NA NA NA
ALA O:109 I:349 0.0 0.0 H -64.8 -45.0 NA NA NA
ALA P:109 M:349 0.0 0.0 H -57.7 -47.9 NA NA NA
2bcq 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:109 A:349 0.0 0.0 H -59.9 -44.3 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.926
4.743
9.150
7.918
5.290
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
2bcr 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:109 A:349 0.0 0.0 H -62.6 -44.5 0.0 0.0 0.0 DG
DT
DA
NA
EDO
HOH
 6.912
4.739
9.230
7.927
6.299
5.278
 N
N
CB
CB
N
O
 O3'
OP1
OP2
NA
C1
O
2bcs 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:109 A:349 0.0 0.0 H -60.7 -48.9 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.868
4.719
9.274
7.951
5.379
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
2bcu 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:109 A:349 0.0 0.0 H -62.4 -47.5 0.0 0.0 0.0 DG
DT
DT
NA
HOH
 6.909
4.772
9.176
7.810
5.357
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
2bcv 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ALA D:109 A:349 0.0 0.0 H -57.7 -46.2 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.827
4.730
9.307
7.961
5.452
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
2gws 4 Q9UGP5 100.0 0.0 X-RAY
 2006-09-05 ALA M:109 A:349 0.0 0.0 H -62.2 -46.9 0.0 0.0 0.0 DG
DC
DG
NA
HOH
 6.763
4.590
9.157
7.910
6.584
 N
N
N
CB
N
 O3'
OP1
OP2
NA
O
ALA N:109 E:349 0.0 0.0 H -67.7 -46.9 NA NA NA
ALA O:109 I:349 0.0 0.0 H -62.7 -51.9 NA NA NA
ALA P:109 M:349 0.0 0.0 H -58.3 -45.5 NA NA NA
4xrh 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:109 B:349 0.0 0.0 H -64.2 -39.1 0.0 0.0 0.0 DA
DG
DT
HOH
 7.041
4.740
9.496
6.159
 N
N
N
C
 O3'
OP1
OP2
O
ALA B:109 A:349 0.0 0.0 H -63.0 -37.2 NA NA NA
5ddm 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:109 B:349 0.0 0.0 H -62.6 -47.3 0.0 0.0 0.0 DA
DG
DT
NA
HOH
 6.795
4.677
9.558
8.335
6.298
 N
N
N
CB
N
 O3'
OP1
OP2
NA
O
ALA B:109 A:349 11.0 0.096 H -71.3 -28.5 NA NA NA
5ddy 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:109 A:349 1.0 0.009 H -67.3 -51.8 1.0 0.009 0.0 MN
 8.516
 CB
 MN
ALA B:109 C:349 1.0 0.009 H -65.6 -34.3 NA NA NA
ALA C:109 E:349 2.0 0.017 H -64.9 -40.1 NA NA NA
ALA D:109 G:349 2.0 0.017 H -83.7 -44.1 NA NA NA
3c5g 1 Q9UGP5 99.7 0.0 X-RAY
 2008-07-29 ALA A:109 A:349 0.0 0.0 H -61.8 -43.8 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.835
4.675
9.094
7.928
5.526
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
ALA E:109 B:349 0.0 0.0 H -57.8 -40.3 NA NA NA
5chg 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:108 A:349 0.0 0.0 H -63.8 -42.9 0.0 0.0 0.0 DA
DG
DT
MG
HOH
 7.115
4.847
9.626
8.242
9.102
 N
N
CB
CB
O
 O3'
OP1
OP2
MG
O
ALA B:108 B:349 0.0 0.0 H -63.0 -29.7 NA NA NA
5cj7 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:108 A:349 0.0 0.0 H -59.5 -42.4 0.0 0.0 0.0 DA
DG
DT
HOH
 6.985
4.864
9.816
9.140
 N
N
N
O
 O3'
OP1
OP1
O
ALA B:108 B:349 0.0 0.0 H -68.1 -38.2 NA NA NA
5cp2 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:108 A:349 17.0 0.148 H -63.8 -37.4 17.0 0.148 0.0 HOH
 9.941
 N
 O
ALA B:108 B:349 0.0 0.0 H -59.5 -46.0 NA NA NA
5cr0 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ALA A:108 A:349 0.0 0.0 H -58.4 -44.1 0.0 0.0 0.0 DA
DG
DT
HOH
 6.989
4.860
9.599
8.254
 N
N
N
CB
 O3'
OP1
OP2
O
ALA B:108 B:349 2.0 0.017 H -64.6 -42.9 NA NA NA
3c5f 4 Q9UGP5 99.7 0.0 X-RAY
 2008-09-02 ALA G:109 A:349 0.0 0.0 H -59.9 -43.7 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.938
4.710
8.952
7.949
6.517
 N
N
N
CB
C
 O3'
OP1
OP2
NA
O
ALA H:109 B:349 0.0 0.0 H -53.2 -47.2 NA NA NA
1xsn 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ALA D:109 A:349 0.0 0.0 H -59.2 -45.3 0.0 0.0 0.0 DG
DT
DA
EDO
EDO
NA
HOH
 6.909
4.749
9.447
7.010
9.747
8.042
5.392
 N
N
N
N
N
CB
O
 O3'
OP1
OP2
C2
O2
NA
O
1xsp 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ALA D:109 A:349 0.0 0.0 H -64.8 -42.7 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.918
4.742
9.200
8.065
5.411
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
2pfn 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:109 A:349 0.0 0.0 H -61.4 -48.3 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.720
4.591
8.963
7.823
5.402
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
2pfo 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:109 A:349 0.0 0.0 H -61.0 -43.2 0.0 0.0 0.0 DG
DT
DA
NA
NA
HOH
 6.911
4.836
8.967
7.766
9.061
5.353
 N
N
N
CB
CB
O
 O3'
OP1
OP2
NA
NA
O
2pfp 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:109 A:349 0.0 0.0 H -61.2 -47.3 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.859
4.690
9.216
7.912
5.347
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
2pfq 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ALA D:109 A:349 0.0 0.0 H -58.6 -45.3 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.757
4.712
9.279
7.972
5.533
 N
N
CB
CB
O
 O3'
OP1
OP2
NA
O
3hw8 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ALA A:109 A:349 1.0 0.009 H -58.5 -46.5 1.0 0.009 0.0 DG
DT
DA
NA
HOH
 6.892
4.807
9.403
8.114
5.287
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3hwt 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ALA A:109 A:349 0.0 0.0 H -61.9 -44.8 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.936
4.728
9.584
8.086
5.941
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
1rzt 4 Q9UGP5 100.0 0.0 X-RAY
 2004-03-02 ALA M:105 A:349 0.0 0.0 H -57.7 -47.5 0.0 0.0 0.0 DG
DC
DG
NA
HOH
 6.823
4.689
9.015
7.793
6.282
 N
N
N
CB
C
 O3'
OP1
OP2
NA
O
ALA N:105 E:349 0.0 0.0 H -64.3 -42.1 NA NA NA
ALA O:105 I:349 0.0 0.0 H -59.2 -38.8 NA NA NA
ALA P:105 M:349 0.0 0.0 H -58.3 -47.1 NA NA NA
4k4g 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ALA A:106 A:349 0.0 0.0 H -60.7 -40.1 0.0 0.0 0.0 DG
DT
DA
CA
HOH
 6.811
4.737
9.098
7.818
5.951
 N
N
N
CB
C
 O3'
OP1
OP2
CA
O
ALA E:106 E:349 0.0 0.0 H -61.7 -42.5 NA NA NA
ALA I:106 I:349 0.0 0.0 H -60.3 -39.0 NA NA NA
ALA M:106 M:349 0.0 0.0 H -58.1 -49.9 NA NA NA
4k4h 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ALA A:106 A:349 0.0 0.0 H -60.1 -36.2 0.0 0.0 0.0 DG
DT
DA
CA
HOH
 6.877
4.758
9.066
7.742
6.179
 N
N
N
CB
C
 O3'
OP1
OP2
CA
O
ALA E:106 E:349 1.0 0.009 H -59.8 -39.2 NA NA NA
ALA I:106 I:349 0.0 0.0 H -59.4 -41.4 NA NA NA
ALA M:106 M:349 0.0 0.0 H -54.1 -52.8 NA NA NA
4k4i 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ALA A:106 A:349 0.0 0.0 H -66.1 -31.3 0.0 0.0 0.0 DG
DT
DA
CA
HOH
 6.923
4.865
9.108
7.818
6.287
 N
N
N
CB
C
 O3'
OP1
OP2
CA
O
ALA E:106 E:349 0.0 0.0 H -61.5 -41.6 NA NA NA
ALA I:106 I:349 0.0 0.0 H -52.6 -49.1 NA NA NA
ALA M:106 M:349 0.0 0.0 H -49.6 -52.4 NA NA NA
3hx0 1 Q9UGP5 98.8 0.0 X-RAY
 2009-08-25 ALA A:109 A:349 2.0 0.017 H -59.8 -34.2 2.0 0.017 0.0 DG
DT
DA
 6.883
4.693
9.071
 N
N
N
 O3'
OP1
OP2
ALA E:109 F:349 1.0 0.009 H -69.2 -40.3 NA NA NA
ALA I:109 K:349 0.0 0.0 H -69.1 -52.0 NA NA NA
ALA M:109 P:349 1.0 0.009 H -62.8 -48.1 NA NA NA
5dkw 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:101 A:349 0.0 0.0 H -56.5 -36.5 0.0 0.0 0.0 DG
DT
DA
HOH
 6.884
4.752
9.267
6.648
 N
N
N
N
 O3'
OP1
OP2
O
ALA B:101 B:349 0.0 0.0 H -59.8 -40.5 NA NA NA
5cb1 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ALA A:100 A:349 0.0 0.0 H -62.5 -45.2 0.0 0.0 0.0
ALA B:100 B:349 0.0 0.0 H -66.1 -43.8 NA NA NA
4x5v 1 Q9UGP5 100.0 0.0 X-RAY
 2015-10-28 ALA A:99 A:349 0.0 0.0 H -59.4 -45.3 0.0 0.0 0.0 DG
DT
DA
MG
HOH
 6.747
4.605
9.170
7.915
5.398
 N
N
CB
CB
O
 O3'
OP1
OP2
MG
O
4xa5 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-10 ALA A:99 A:349 0.0 0.0 H -54.3 -47.6 0.0 0.0 0.0 DG
DT
DA
MG
HOH
 6.836
4.732
9.294
7.925
5.581
 N
N
CB
CB
O
 O3'
OP1
OP2
MG
O
4xus 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-03 ALA A:99 A:349 0.0 0.0 H -61.6 -41.8 0.0 0.0 0.0 DG
DT
DA
MG
HOH
 7.036
4.857
9.444
7.921
5.444
 N
N
N
CB
O
 O3'
OP1
OP2
MG
O
5cwr 1 Q9UGP5 99.69 0.0 X-RAY
 2016-02-24 ALA A:100 A:349 0.0 0.0 H -64.3 -40.6 0.0 0.0 0.0 DG
DT
DA
HOH
 6.896
4.774
9.133
6.009
 N
N
N
O
 O3'
OP1
OP2
O
ALA D:100 B:349 0.0 0.0 H -62.8 -42.4 NA NA NA
3mda 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ALA A:99 A:349 0.0 0.0 H -56.5 -45.6 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.881
4.768
9.328
7.975
5.290
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3mdc 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ALA A:99 A:349 0.0 0.0 H -58.5 -46.6 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.992
4.869
9.313
8.093
5.401
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3mgh 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ALA A:108 A:349 0.0 0.0 H -57.7 -44.4 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 7.061
4.808
9.062
8.339
6.751
 N
N
N
CB
N
 O3'
OP1
OP2
NA
O
ALA E:108 C:349 0.0 0.0 H -70.2 -14.8 NA NA NA
3mgi 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ALA A:108 A:349 0.0 0.0 H -59.3 -47.8 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.756
4.617
9.528
8.526
5.414
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3pml 1 Q9UGP5 97.6 0.0 X-RAY
 2011-01-26 ALA A:108 A:349 0.0 0.0 H -62.4 -42.8 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.803
4.720
8.948
8.129
6.545
 N
N
N
CB
N
 O3'
OP1
OP2
NA
O
ALA B:108 B:349 0.0 0.0 H -63.7 -40.0 NA NA NA
3pmn 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ALA A:108 A:349 0.0 0.0 H -63.2 -45.1 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.846
4.755
9.227
7.983
5.331
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3pnc 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ALA A:108 A:349 0.0 0.0 H -60.4 -45.6 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.883
4.801
9.272
7.994
5.191
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3upq 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ALA A:108 A:349 0.0 0.0 H -60.7 -42.0 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.859
4.760
9.212
8.172
5.416
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3uq0 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ALA A:108 A:349 0.0 0.0 H -57.7 -47.9 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.888
4.733
8.714
7.876
5.390
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
3uq2 1 Q9UGP5 97.31 0.0 X-RAY
 2012-05-23 ALA A:108 A:349 0.0 0.0 H -62.2 -45.5 0.0 0.0 0.0 DG
DT
DA
NA
HOH
 6.773
4.665
9.247
7.968
5.622
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O
4fo6 1 Q9UGP5 97.31 0.0 X-RAY
 2012-07-11 ALA A:108 A:349 1.0 0.009 H -62.6 -41.7 1.0 0.009 0.0 DG
DT
DA
NA
HOH
 6.921
4.776
9.251
7.929
5.420
 N
N
N
CB
O
 O3'
OP1
OP2
NA
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugp5-f1 1 Q9UGP5 100.0 0.0 ALA A:349 A:349 0.0 0.0 H -57.5 -44.5