Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 103343311 . T A CCDS7513.1:NM_001174084.1:c.1019aAc>aTc_NP_001167555.1:p.340N>I Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xq8 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ASN A:99 B:340 88.0 0.55 T -83.6 6.4 88.0 0.55 0.0 DG
DT
DA
HOH
 8.330
6.359
9.651
2.242
 C
C
O
O
 O3'
OP1
OP1
O
ASN B:99 A:340 70.0 0.438 T -85.3 9.4 NA NA NA
5ca7 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ASN A:99 B:340 62.0 0.388 T -78.5 -1.3 62.0 0.388 0.0 DG
DT
DA
HOH
 8.390
6.307
9.483
2.845
 C
C
O
O
 O3'
OP1
OP2
O
ASN B:99 A:340 91.0 0.569 T -79.4 5.6 NA NA NA
5iii 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ASN A:99 A:340 69.0 0.431 T -80.7 1.2 69.0 0.431 0.0 DT
DA
DOC
NA
HOH
 8.427
6.294
9.619
4.186
2.705
 C
C
O
C
O
 O3'
OP1
OP2
NA
O
5iij 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ASN A:99 A:340 67.0 0.419 T -83.3 1.6 67.0 0.419 0.0 DT
DA
DOC
NA
HOH
 8.430
6.312
9.822
4.167
2.658
 C
C
O
C
O
 O3'
OP1
OP1
NA
O
5iik 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ASN A:99 A:340 84.0 0.525 T -79.2 1.9 84.0 0.525 0.0 DT
DA
DC
CIT
NA
HOH
 8.460
6.315
9.597
9.781
4.228
2.684
 C
C
O
OD1
C
ND2
 O3'
OP1
OP2
O2
NA
O
5iil 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ASN A:99 A:340 77.0 0.481 T -83.9 4.4 77.0 0.481 0.0 DT
DA
DA
CIT
NA
HOH
 8.443
6.364
9.759
9.545
4.240
2.702
 C
C
O
OD1
C
ND2
 O3'
OP1
OP1
O2
NA
O
5iim 1 Q9UGP5 100.0 0.0 X-RAY
 2016-09-07 ASN A:99 A:340 56.0 0.35 T -81.7 -1.1 56.0 0.35 0.0 DT
DA
DA
NA
HOH
 8.452
6.258
9.779
4.234
2.780
 C
C
O
C
O
 O3'
OP1
OP1
NA
O
5iin 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ASN A:99 A:340 63.0 0.394 T -78.5 -1.6 63.0 0.394 0.0 DT
DA
DC
NA
HOH
 8.479
6.247
9.695
4.295
2.572
 C
C
O
N
ND2
 O3'
OP1
OP1
NA
O
5iio 4 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 ASN M:99 A:340 59.0 0.369 T -78.2 -5.4 59.0 0.369 0.0 DT
DA
NA
HOH
 8.681
6.423
4.250
2.692
 C
C
N
OD1
 O3'
OP1
NA
O
ASN N:99 E:340 61.0 0.381 T -83.5 -1.5 NA NA NA
ASN O:99 I:340 59.0 0.369 T -71.6 -11.1 NA NA NA
ASN P:99 M:340 46.0 0.287 T -69.3 -10.7 NA NA NA
1xsl 4 Q9UGP5 100.0 0.0 X-RAY
 2005-01-18 ASN M:100 A:340 58.0 0.362 T -78.1 -6.8 58.0 0.362 0.0 DC
DG
NA
HOH
 8.637
6.404
4.402
2.735
 C
C
C
O
 O3'
OP1
NA
O
ASN N:100 E:340 57.0 0.356 T -89.2 -6.4 NA NA NA
ASN O:100 I:340 62.0 0.388 T -71.9 -8.4 NA NA NA
ASN P:100 M:340 50.0 0.312 T -77.4 -7.4 NA NA NA
2bcq 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ASN D:100 A:340 64.0 0.4 T -84.9 2.8 64.0 0.4 0.0 DT
DA
DC
NA
HOH
 8.369
6.195
9.452
4.103
2.652
 C
C
O
C
ND2
 O3'
OP1
OP1
NA
O
2bcr 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ASN D:100 A:340 78.0 0.487 T -78.9 2.2 78.0 0.487 0.0 DT
DA
DC
NA
HOH
 8.357
6.208
9.534
4.142
2.754
 C
C
O
C
O
 O3'
OP1
OP1
NA
O
2bcs 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ASN D:100 A:340 58.0 0.362 T -77.8 1.2 58.0 0.362 0.0 DT
DA
DC
NA
HOH
 8.386
6.191
9.539
4.266
2.472
 C
C
O
C
ND2
 O3'
OP1
OP1
NA
O
2bcu 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ASN D:100 A:340 67.0 0.419 T -82.1 3.0 67.0 0.419 0.0 DT
DT
DC
NA
HOH
 8.555
6.282
9.384
4.341
2.609
 C
C
O
C
ND2
 O3'
OP1
OP2
NA
O
2bcv 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 ASN D:100 A:340 66.0 0.412 T -92.6 1.9 66.0 0.412 0.0 DT
DA
O2C
NA
HOH
 8.312
6.215
9.952
4.090
2.650
 C
C
O
C
OD1
 O3'
OP1
O1P
NA
O
2gws 4 Q9UGP5 100.0 0.0 X-RAY
 2006-09-05 ASN M:100 A:340 57.0 0.356 T -72.1 -7.2 57.0 0.356 0.0 DC
DG
NA
HOH
 8.655
6.403
4.427
2.850
 C
C
N
O
 O3'
OP1
NA
O
ASN N:100 E:340 60.0 0.375 T -80.1 -7.8 NA NA NA
ASN O:100 I:340 63.0 0.394 T -65.4 -11.1 NA NA NA
ASN P:100 M:340 52.0 0.325 T -73.9 -8.5 NA NA NA
4xrh 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ASN A:100 B:340 68.0 0.425 T -75.5 -0.9 68.0 0.425 0.0 DG
DT
DA
 8.346
6.283
9.542
 C
C
O
 O3'
OP1
OP2
ASN B:100 A:340 75.0 0.469 T -82.5 6.2 NA NA NA
5ddm 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ASN A:100 B:340 66.0 0.412 T -82.1 0.3 66.0 0.412 0.0 DG
DT
DA
NA
HOH
 8.472
6.460
9.770
4.318
2.636
 C
C
O
C
O
 O3'
OP1
OP2
NA
O
ASN B:100 A:340 100.0 0.625 T -79.5 5.9 NA NA NA
5ddy 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ASN A:100 A:340 51.0 0.319 T -76.6 -8.7 51.0 0.319 0.0 MN
HOH
 4.173
5.850
 CA
OD1
 MN
O
ASN B:100 C:340 54.0 0.338 T -69.9 -12.7 NA NA NA
ASN C:100 E:340 71.0 0.444 T -68.8 -18.6 NA NA NA
ASN D:100 G:340 76.0 0.475 T -69.2 -21.8 NA NA NA
3c5g 1 Q9UGP5 99.7 0.0 X-RAY
 2008-07-29 ASN A:100 A:340 58.0 0.362 T -79.8 -8.4 58.0 0.362 0.0 DT
DA
2DT
NA
HOH
 8.485
6.391
9.648
4.229
2.723
 C
C
O
C
O
 O3'
OP1
OP1
NA
O
ASN E:100 B:340 65.0 0.406 T -80.9 -8.1 NA NA NA
5chg 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ASN A:99 A:340 85.0 0.531 T -79.0 -0.2 85.0 0.531 0.0 DG
DT
DA
MG
HOH
 8.325
6.322
9.489
4.360
3.303
 C
C
O
C
O
 O3'
OP1
OP2
MG
O
ASN B:99 B:340 75.0 0.469 T -87.7 7.6 NA NA NA
5cj7 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ASN A:99 A:340 65.0 0.406 T -71.3 -5.8 65.0 0.406 0.0 DG
DT
DA
HOH
 8.401
6.352
9.407
9.490
 C
C
O
O
 O3'
OP1
OP1
O
ASN B:99 B:340 79.0 0.494 T -84.4 7.2 NA NA NA
5cp2 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ASN A:99 A:340 84.0 0.525 T -64.8 -24.6 84.0 0.525 0.0
ASN B:99 B:340 59.0 0.369 T -84.2 -0.1 NA NA NA
5cr0 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 ASN A:99 A:340 69.0 0.431 T -77.1 -3.9 69.0 0.431 0.0 DG
DT
DA
HOH
 8.491
6.431
9.674
4.422
 C
C
O
C
 O3'
OP1
OP2
O
ASN B:99 B:340 79.0 0.494 T -70.5 -9.2 NA NA NA
3c5f 4 Q9UGP5 99.7 0.0 X-RAY
 2008-09-02 ASN G:100 A:340 58.0 0.362 T -80.6 -9.7 58.0 0.362 0.0 DT
DA
DC
NA
HOH
 8.532
6.341
9.560
4.335
2.741
 C
C
O
C
O
 O3'
OP1
OP1
NA
O
ASN H:100 B:340 62.0 0.388 T -81.6 -6.5 NA NA NA
1xsn 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ASN D:100 A:340 67.0 0.419 T -86.2 2.7 67.0 0.419 0.0 DT
DA
NA
HOH
 8.357
6.316
4.163
2.717
 C
C
C
ND2
 O3'
OP1
NA
O
1xsp 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 ASN D:100 A:340 59.0 0.369 T -86.5 1.5 59.0 0.369 0.0 DT
DA
DC
NA
HOH
 8.449
6.276
9.534
4.176
2.480
 C
C
O
C
ND2
 O3'
OP1
OP2
NA
O
2pfn 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ASN D:100 A:340 64.0 0.4 T -85.8 1.8 64.0 0.4 0.0 DT
DA
DC
NA
NA
HOH
 8.361
6.148
9.510
6.107
4.215
2.656
 C
C
O
O
C
OD1
 O3'
OP1
OP1
NA
NA
O
2pfo 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ASN D:100 A:340 62.0 0.388 T -82.8 -2.0 62.0 0.388 0.0 DT
DA
DC
NA
NA
HOH
 8.523
6.216
9.458
4.313
4.153
2.495
 C
C
O
N
OD1
ND2
 O3'
OP1
OP1
NA
NA
O
2pfp 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ASN D:100 A:340 66.0 0.412 T -85.4 2.0 66.0 0.412 0.0 DT
DA
DC
NA
HOH
 8.452
6.228
9.750
4.209
2.590
 C
C
O
C
ND2
 O3'
OP1
OP1
NA
O
2pfq 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 ASN D:100 A:340 64.0 0.4 T -80.8 7.5 64.0 0.4 0.0 DT
DA
DC
NA
HOH
 8.588
6.332
9.757
4.248
2.494
 C
C
O
C
ND2
 O3'
OP1
OP1
NA
O
3hw8 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ASN A:100 A:340 65.0 0.406 T -87.0 1.3 65.0 0.406 0.0 DT
DA
DT
NA
HOH
 8.361
6.271
9.994
4.151
2.667
 C
C
O
C
O
 O3'
OP1
OP1
NA
O
3hwt 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 ASN A:100 A:340 69.0 0.431 T -81.5 6.0 69.0 0.431 0.0 DT
DA
NA
HOH
 8.424
6.318
4.155
2.670
 C
C
C
ND2
 O3'
OP1
NA
O
1rzt 4 Q9UGP5 100.0 0.0 X-RAY
 2004-03-02 ASN M:96 A:340 52.0 0.325 T -78.1 -4.5 52.0 0.325 0.0 DC
DG
NA
HOH
 8.766
6.422
4.335
2.807
 C
C
C
O
 O3'
OP1
NA
O
ASN N:96 E:340 63.0 0.394 T -76.8 -3.3 NA NA NA
ASN O:96 I:340 60.0 0.375 T -78.4 -7.1 NA NA NA
ASN P:96 M:340 56.0 0.35 T -79.3 -5.0 NA NA NA
4k4g 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ASN A:97 A:340 53.0 0.331 T -72.7 -8.9 53.0 0.331 0.0 DT
DA
DC
CA
HOH
 8.492
6.356
9.517
4.350
2.732
 C
C
O
C
O
 O3'
OP1
OP1
CA
O
ASN E:97 E:340 56.0 0.35 T -62.5 -2.7 NA NA NA
ASN I:97 I:340 54.0 0.338 T -68.9 -10.3 NA NA NA
ASN M:97 M:340 47.0 0.294 T -73.6 -1.2 NA NA NA
4k4h 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ASN A:97 A:340 58.0 0.362 T -75.0 -3.1 58.0 0.362 0.0 DT
DA
DC
CA
HOH
 8.462
6.356
9.631
4.409
2.561
 C
C
O
C
O
 O3'
OP1
OP1
CA
O
ASN E:97 E:340 49.0 0.306 T -68.9 -4.9 NA NA NA
ASN I:97 I:340 58.0 0.362 T -67.1 -14.4 NA NA NA
ASN M:97 M:340 45.0 0.281 T -67.7 -9.0 NA NA NA
4k4i 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 ASN A:97 A:340 59.0 0.369 T -72.6 -9.3 59.0 0.369 0.0 DT
DA
DC
CA
HOH
 8.393
6.315
9.591
4.325
2.699
 C
C
O
C
O
 O3'
OP1
OP2
CA
O
ASN E:97 E:340 47.0 0.294 T -69.7 -4.7 NA NA NA
ASN I:97 I:340 63.0 0.394 T -68.3 -13.3 NA NA NA
ASN M:97 M:340 45.0 0.281 T -73.3 -8.7 NA NA NA
3hx0 1 Q9UGP5 98.8 0.0 X-RAY
 2009-08-25 ASN A:100 A:340 79.0 0.494 T -72.0 -1.6 79.0 0.494 0.0 DT
DA
DT
HOH
 8.330
6.248
9.793
8.668
 C
C
O
O
 O3'
OP1
OP1
O
ASN E:100 F:340 78.0 0.487 T -65.8 4.1 NA NA NA
ASN I:100 K:340 67.0 0.419 T -66.7 -3.2 NA NA NA
ASN M:100 P:340 69.0 0.431 T -65.2 -33.0 NA NA NA
5dkw 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ASN A:92 A:340 54.0 0.338 T -82.9 10.9 54.0 0.338 0.0 DT
DA
HOH
 8.668
6.475
2.548
 C
C
O
 O3'
OP1
O
ASN B:92 B:340 57.0 0.356 T -88.0 4.3 NA NA NA
5cb1 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 ASN A:91 A:340 50.0 0.312 T -69.0 -15.6 50.0 0.312 0.0
ASN B:91 B:340 62.0 0.388 T -70.5 -8.7 NA NA NA
4x5v 1 Q9UGP5 100.0 0.0 X-RAY
 2015-10-28 ASN A:90 A:340 84.0 0.525 T -80.5 0.6 84.0 0.525 0.0 DT
DA
DC
MG
CIT
HOH
 8.370
6.169
9.229
4.252
9.716
2.739
 C
C
O
C
OD1
O
 O3'
OP1
OP2
MG
O1
O
4xa5 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-10 ASN A:90 A:340 66.0 0.412 T -80.1 -0.2 66.0 0.412 0.0 DT
DA
DOC
MG
HOH
 8.470
6.359
9.649
4.309
2.720
 N
C
O
C
O
 O3'
OP1
OP2
MG
O
4xus 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-03 ASN A:90 A:340 66.0 0.412 T -79.9 6.0 66.0 0.412 0.0 DT
DA
MG
HOH
 8.581
6.426
4.223
2.704
 C
C
N
O
 O3'
OP1
MG
O
5cwr 1 Q9UGP5 99.69 0.0 X-RAY
 2016-02-24 ASN A:91 A:340 46.0 0.287 T -75.8 -8.1 46.0 0.287 0.0 DT
DA
DC
HOH
 8.678
6.427
9.513
2.787
 C
C
O
O
 O3'
OP1
OP1
O
ASN D:91 B:340 53.0 0.331 T -78.5 -8.2 NA NA NA
3mda 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ASN A:90 A:340 63.0 0.394 T -81.7 -1.3 63.0 0.394 0.0 DT
DA
DC
NA
HOH
 8.499
6.414
9.694
4.312
2.518
 C
C
O
C
ND2
 O3'
OP1
OP1
NA
O
3mdc 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 ASN A:90 A:340 64.0 0.4 T -81.3 1.6 64.0 0.4 0.0 DT
DA
DC
NA
HOH
 8.417
6.321
9.493
4.148
2.613
 C
C
O
C
ND2
 O3'
OP1
OP1
NA
O
3mgh 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ASN A:99 A:340 49.0 0.306 T -84.8 -5.5 49.0 0.306 0.0 DT
DA
DC
NA
HOH
 8.505
6.279
9.823
3.881
2.669
 C
C
O
C
OD1
 O3'
OP1
OP2
NA
O
ASN E:99 C:340 51.0 0.319 T -78.0 -9.8 NA NA NA
3mgi 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 ASN A:99 A:340 64.0 0.4 T -102.4 9.0 64.0 0.4 0.0 DT
DA
NA
HOH
 8.431
6.461
4.040
2.766
 C
C
C
OD1
 O3'
OP1
NA
O
3pml 1 Q9UGP5 97.6 0.0 X-RAY
 2011-01-26 ASN A:99 A:340 55.0 0.344 T -81.9 -16.4 55.0 0.344 0.0 DT
DA
DC
NA
HOH
 8.315
6.152
9.219
4.028
2.688
 C
C
O
C
OD1
 O3'
OP1
OP1
NA
O
ASN B:99 B:340 60.0 0.375 T -78.7 -5.8 NA NA NA
3pmn 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ASN A:99 A:340 56.0 0.35 T -80.4 0.5 56.0 0.35 0.0 DT
DA
DG
NA
HOH
 8.494
6.347
9.782
4.291
2.781
 C
C
O
C
O
 O3'
OP1
OP1
NA
O
3pnc 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 ASN A:99 A:340 57.0 0.356 T -84.1 -2.0 57.0 0.356 0.0 DT
DA
DG
NA
TRS
HOH
 8.501
6.315
9.708
4.261
8.013
2.581
 C
C
O
C
O
ND2
 O3'
OP1
OP1
NA
O3
O
3upq 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ASN A:99 A:340 70.0 0.438 T -79.6 -1.6 70.0 0.438 0.0 DT
DA
DC
NA
HOH
 8.605
6.497
9.893
4.303
2.728
 C
C
O
C
O
 O3'
OP1
OP2
NA
O
3uq0 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 ASN A:99 A:340 64.0 0.4 T -83.8 -1.5 64.0 0.4 0.0 DT
DA
DC
NA
HOH
 8.397
6.076
8.195
4.054
2.683
 C
C
O
C
O
 O3'
OP1
OP2
NA
O
3uq2 1 Q9UGP5 97.31 0.0 X-RAY
 2012-05-23 ASN A:99 A:340 80.0 0.5 T -83.3 -1.6 80.0 0.5 0.0 DT
DA
C
NA
HOH
 8.461
6.231
9.288
4.229
2.488
 C
C
O
C
ND2
 O3'
OP1
OP2
NA
O
4fo6 1 Q9UGP5 97.31 0.0 X-RAY
 2012-07-11 ASN A:99 A:340 79.0 0.494 T -82.2 -2.7 79.0 0.494 0.0 DT
DA
C
NA
HOH
 8.349
6.220
9.498
4.105
2.614
 C
C
O
C
ND2
 O3'
OP1
OP2
NA
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugp5-f1 1 Q9UGP5 100.0 0.0 ASN A:340 A:340 51.0 0.319 T -81.9 -12.0