Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 103344471 . A C CCDS7513.1:NM_001174084.1:c.779cTg>cGg_NP_001167555.1:p.260L>R Homo sapiens DNA polymerase lambda (POLL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xq8 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 LEU A:19 NA:NA DO NA DO DO DO NA NA NA
LEU B:19 NA:NA DO NA DO DO DO NA NA NA
5ca7 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 LEU A:19 NA:NA DO NA DO DO DO NA NA NA
LEU B:19 NA:NA DO NA DO DO DO NA NA NA
5iii 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 LEU A:19 A:260 0.0 0.0 H -63.0 -29.8 0.0 0.0 0.0 DG
DC
HOH
 8.069
8.822
6.784
 CD2
CD1
N
 OP1
OP1
O
5iij 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 LEU A:19 A:260 0.0 0.0 H -64.3 -31.9 0.0 0.0 0.0 DG
DC
HOH
 7.958
8.959
6.940
 CD2
CD1
O
 OP1
OP1
O
5iik 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 LEU A:19 A:260 0.0 0.0 H -67.5 -30.2 0.0 0.0 0.0 DG
DC
HOH
 8.748
9.182
5.876
 CD2
CD1
N
 C4'
OP1
O
5iil 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 LEU A:19 A:260 0.0 0.0 H -66.3 -34.6 0.0 0.0 0.0 DG
DC
HOH
 8.781
9.140
6.124
 CD2
CD1
C
 C4'
OP1
O
5iim 1 Q9UGP5 100.0 0.0 X-RAY
 2016-09-07 LEU A:19 A:260 0.0 0.0 H -65.7 -34.8 0.0 0.0 0.0 DG
DC
HOH
 8.618
9.259
7.513
 CD2
CD1
O
 O5'
OP1
O
5iin 1 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 LEU A:19 A:260 2.0 0.012 H -66.6 -30.9 2.0 0.012 0.0 DG
DC
 8.296
8.952
 CD2
CD1
 OP1
OP1
5iio 4 Q9UGP5 100.0 0.0 X-RAY
 2016-08-17 LEU M:19 A:260 0.0 0.0 H -59.3 -38.8 0.0 0.0 0.0 DG
DC
HOH
 8.317
9.186
6.528
 CD2
CD1
CD2
 OP1
OP1
O
LEU N:19 E:260 0.0 0.0 H -72.5 -35.8 NA NA NA
LEU O:19 I:260 0.0 0.0 H -64.4 -36.1 NA NA NA
LEU P:19 M:260 0.0 0.0 H -70.1 -33.9 NA NA NA
1xsl 4 Q9UGP5 100.0 0.0 X-RAY
 2005-01-18 LEU M:20 A:260 0.0 0.0 H -73.1 -32.8 0.0 0.0 0.0 DG
DC
HOH
 8.353
9.515
6.269
 CD2
CD1
N
 OP1
OP1
O
LEU N:20 E:260 0.0 0.0 H -47.5 -52.4 NA NA NA
LEU O:20 I:260 0.0 0.0 H -69.6 -32.8 NA NA NA
LEU P:20 M:260 0.0 0.0 H -61.0 -34.5 NA NA NA
2bcq 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 LEU D:20 A:260 0.0 0.0 H -65.1 -34.4 0.0 0.0 0.0 DG
DC
HOH
 7.888
8.913
6.320
 CD2
CD1
N
 OP1
OP1
O
2bcr 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 LEU D:20 A:260 3.0 0.018 H -69.6 -27.2 3.0 0.018 0.0 DG
DC
HOH
 8.955
9.208
6.088
 CD2
CD1
O
 O3'
OP1
O
2bcs 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 LEU D:20 A:260 0.0 0.0 H -69.4 -43.7 0.0 0.0 0.0 DG
DC
HOH
 8.763
9.411
7.455
 CD2
CD2
O
 C4'
OP1
O
2bcu 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 LEU D:20 A:260 0.0 0.0 H -74.4 -39.6 0.0 0.0 0.0 DG
DC
HOH
 8.821
9.351
8.173
 CD2
CD1
N
 C4'
OP1
O
2bcv 4 Q9UGP5 100.0 0.0 X-RAY
 2006-03-07 LEU D:20 A:260 5.0 0.029 H -78.2 -30.4 5.0 0.029 0.0 DG
DC
HOH
 7.948
8.952
9.548
 CD2
CD1
O
 O5'
OP1
O
2gws 4 Q9UGP5 100.0 0.0 X-RAY
 2006-09-05 LEU M:20 A:260 0.0 0.0 H -62.7 -33.6 0.0 0.0 0.0 DG
DC
HOH
 8.377
9.381
6.657
 CD2
CD1
N
 OP1
OP1
O
LEU N:20 E:260 0.0 0.0 H -50.6 -47.2 NA NA NA
LEU O:20 I:260 0.0 0.0 H -65.6 -38.3 NA NA NA
LEU P:20 M:260 0.0 0.0 H -58.9 -43.1 NA NA NA
4xrh 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 LEU A:20 NA:NA DO NA DO DO DO NA NA NA
LEU B:20 NA:NA DO NA DO DO DO NA NA NA
5ddm 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 LEU A:20 NA:NA DO NA DO DO DO NA NA NA
LEU B:20 NA:NA DO NA DO DO DO NA NA NA
5ddy 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 LEU A:20 A:260 0.0 0.0 H -69.3 -28.6 0.0 0.0 0.0
LEU B:20 C:260 2.0 0.012 H -69.6 -38.0 NA NA NA
LEU C:20 NA:NA DO NA DO DO DO NA NA NA
LEU D:20 NA:NA DO NA DO DO DO NA NA NA
3c5g 1 Q9UGP5 99.7 0.0 X-RAY
 2008-07-29 LEU A:20 A:260 0.0 0.0 H -56.3 -38.0 0.0 0.0 0.0 DG
DC
HOH
 8.311
9.242
5.589
 CD2
CD1
O
 OP1
OP1
O
LEU E:20 B:260 0.0 0.0 H -63.3 -34.6 NA NA NA
5chg 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 LEU A:19 NA:NA DO NA DO DO DO NA NA NA
LEU B:19 NA:NA DO NA DO DO DO NA NA NA
5cj7 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 LEU A:19 NA:NA DO NA DO DO DO NA NA NA
LEU B:19 NA:NA DO NA DO DO DO NA NA NA
5cp2 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 LEU A:19 NA:NA DO NA DO DO DO NA NA NA
LEU B:19 NA:NA DO NA DO DO DO NA NA NA
5cr0 1 Q9UGP5 99.7 0.0 X-RAY
 2016-02-24 LEU A:19 NA:NA DO NA DO DO DO NA NA NA
LEU B:19 NA:NA DO NA DO DO DO NA NA NA
3c5f 4 Q9UGP5 99.7 0.0 X-RAY
 2008-09-02 LEU G:20 A:260 0.0 0.0 H -61.8 -36.0 0.0 0.0 0.0 DG
DC
HOH
 8.461
8.961
6.397
 CD2
CD1
N
 OP1
OP1
O
LEU H:20 B:260 0.0 0.0 H -59.7 -31.6 NA NA NA
1xsn 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 LEU D:20 A:260 5.0 0.029 H -78.8 -37.7 5.0 0.029 0.0 DG
DC
HOH
 8.839
9.132
6.497
 CD2
CD1
N
 O3'
OP1
O
1xsp 4 Q9UGP5 99.7 0.0 X-RAY
 2005-01-18 LEU D:20 A:260 4.0 0.024 H -75.1 -41.5 4.0 0.024 0.0 DG
DC
HOH
 8.752
9.335
8.315
 CD2
CD2
CD2
 O3'
OP1
O
2pfn 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 LEU D:20 A:260 3.0 0.018 H -77.9 -32.0 3.0 0.018 0.0 DG
DC
HOH
 7.935
9.216
8.879
 CD2
CD1
CD2
 OP1
OP1
O
2pfo 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 LEU D:20 A:260 4.0 0.024 H -72.9 -33.8 4.0 0.024 0.0 DG
DC
HOH
 8.206
9.039
7.332
 CD2
CD1
O
 O5'
OP1
O
2pfp 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 LEU D:20 A:260 0.0 0.0 H -74.6 -37.3 0.0 0.0 0.0 DG
DC
HOH
 8.058
9.035
5.493
 CD2
CD1
O
 OP1
OP1
O
2pfq 4 Q9UGP5 99.7 0.0 X-RAY
 2007-05-15 LEU D:20 A:260 2.0 0.012 H -84.0 -39.6 2.0 0.012 0.0 DG
DC
HOH
 8.441
9.017
6.334
 CD2
CD1
N
 O5'
OP1
O
3hw8 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 LEU A:20 A:260 6.0 0.035 H -64.6 -43.7 6.0 0.035 0.0 DG
DC
HOH
 8.289
8.955
9.298
 CD2
CD2
CD1
 O5'
OP1
O
3hwt 1 Q9UGP5 99.7 0.0 X-RAY
 2009-08-25 LEU A:20 A:260 13.0 0.076 H -69.9 -19.7 13.0 0.076 0.0 DG
DC
HOH
 8.024
8.749
7.286
 CD2
CD2
N
 C4'
OP1
O
1rzt 4 Q9UGP5 100.0 0.0 X-RAY
 2004-03-02 LEU M:16 A:260 0.0 0.0 H -71.3 -34.0 0.0 0.0 0.0 DG
DC
HOH
 8.257
9.135
4.985
 CD2
CD1
O
 OP1
OP1
O
LEU N:16 E:260 1.0 0.006 H -64.6 -39.0 NA NA NA
LEU O:16 I:260 0.0 0.0 H -58.4 -39.6 NA NA NA
LEU P:16 M:260 0.0 0.0 H -56.9 -34.0 NA NA NA
4k4g 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 LEU A:17 A:260 0.0 0.0 H -67.8 -32.3 0.0 0.0 0.0 DG
DC
HOH
 7.997
9.043
8.851
 CD2
CD2
CD2
 OP1
OP1
O
LEU E:17 E:260 0.0 0.0 H -58.3 -32.9 NA NA NA
LEU I:17 I:260 0.0 0.0 H -73.0 -39.6 NA NA NA
LEU M:17 M:260 0.0 0.0 H -66.9 -33.4 NA NA NA
4k4h 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 LEU A:17 A:260 0.0 0.0 H -70.1 -29.7 0.0 0.0 0.0 DG
DC
HOH
 8.036
8.912
8.880
 CD2
CD1
CD2
 OP1
OP1
O
LEU E:17 E:260 0.0 0.0 H -57.4 -38.0 NA NA NA
LEU I:17 I:260 0.0 0.0 H -73.4 -37.2 NA NA NA
LEU M:17 M:260 0.0 0.0 H -58.0 -36.3 NA NA NA
4k4i 1 Q9UGP5 100.0 0.0 X-RAY
 2014-07-16 LEU A:17 A:260 0.0 0.0 H -67.3 -35.4 0.0 0.0 0.0 DG
DC
HOH
 8.044
9.051
9.356
 CD2
CD2
CD1
 OP1
OP1
O
LEU E:17 E:260 0.0 0.0 H -59.7 -33.8 NA NA NA
LEU I:17 I:260 0.0 0.0 H -69.5 -33.2 NA NA NA
LEU M:17 M:260 0.0 0.0 H -62.1 -33.6 NA NA NA
3hx0 1 Q9UGP5 98.8 0.0 X-RAY
 2009-08-25 LEU A:20 A:260 3.0 0.018 H -53.1 -36.1 3.0 0.018 0.0 DG
DC
HOH
 8.199
9.042
9.970
 CD2
CD2
O
 O5'
OP1
O
LEU E:20 F:260 0.0 0.0 H -59.1 -37.6 NA NA NA
LEU I:20 K:260 0.0 0.0 H -52.5 -56.9 NA NA NA
LEU M:20 P:260 0.0 0.0 H -68.4 -52.2 NA NA NA
5dkw 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 LEU A:12 A:260 1.0 0.006 H -65.9 -32.7 1.0 0.006 0.0 DG
DC
HOH
 8.454
8.930
8.098
 CD2
CD1
N
 OP2
OP1
O
LEU B:12 B:260 0.0 0.0 H -72.5 -36.2 NA NA NA
5cb1 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-24 LEU A:11 A:260 0.0 0.0 H -77.4 -35.0 0.0 0.0 0.0
LEU B:11 NA:NA DO NA DO DO DO NA NA NA
4x5v 1 Q9UGP5 100.0 0.0 X-RAY
 2015-10-28 LEU A:10 A:260 7.0 0.041 H -68.2 -34.3 7.0 0.041 0.0 DG
DC
HOH
 8.506
9.213
7.579
 CD2
CD2
O
 O5'
OP1
O
4xa5 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-10 LEU A:10 A:260 0.0 0.0 H -64.8 -36.0 0.0 0.0 0.0 DG
DC
ACT
HOH
 8.028
9.064
9.437
6.099
 CD2
CD2
O
N
 O5'
OP1
O
O
4xus 1 Q9UGP5 100.0 0.0 X-RAY
 2016-02-03 LEU A:10 A:260 0.0 0.0 H -67.5 -25.6 0.0 0.0 0.0 DG
DC
HOH
 8.628
8.850
6.400
 CD2
CD1
N
 OP2
OP1
O
5cwr 1 Q9UGP5 99.69 0.0 X-RAY
 2016-02-24 LEU A:11 A:260 0.0 0.0 H -66.8 -36.1 0.0 0.0 0.0 DG
DC
HOH
 7.785
9.267
6.302
 CD2
CD2
C
 OP3
OP1
O
LEU D:11 B:260 0.0 0.0 H -68.1 -30.5 NA NA NA
3mda 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 LEU A:10 A:260 0.0 0.0 H -70.7 -36.1 0.0 0.0 0.0 DG
DC
HOH
 7.954
8.993
8.822
 CD2
CD1
CD2
 OP1
OP1
O
3mdc 1 Q9UGP5 100.0 0.0 X-RAY
 2010-04-28 LEU A:10 A:260 0.0 0.0 H -64.2 -28.1 0.0 0.0 0.0 DG
DC
HOH
 8.016
8.971
6.305
 CD2
CD1
CD1
 OP3
OP1
O
3mgh 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 LEU A:19 A:260 0.0 0.0 H -57.8 -41.4 0.0 0.0 0.0 DG
DC
HOH
 8.185
9.283
6.683
 CD2
CD1
N
 OP2
OP1
O
LEU E:19 C:260 0.0 0.0 H -56.5 -40.1 NA NA NA
3mgi 1 Q9UGP5 97.6 0.0 X-RAY
 2010-05-19 LEU A:19 A:260 0.0 0.0 H -79.6 -36.0 0.0 0.0 0.0 DG
DC
HOH
 8.459
9.265
7.736
 CD2
CD1
O
 O5'
OP1
O
3pml 1 Q9UGP5 97.6 0.0 X-RAY
 2011-01-26 LEU A:19 A:260 0.0 0.0 H -63.0 -46.0 0.0 0.0 0.0 DG
DC
HOH
 8.562
9.139
4.889
 CD2
CD1
O
 OP2
OP1
O
LEU B:19 B:260 0.0 0.0 H -65.1 -32.6 NA NA NA
3pmn 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 LEU A:19 A:260 0.0 0.0 H -67.9 -34.4 0.0 0.0 0.0 DG
DC
HOH
 8.960
9.133
6.976
 CD1
CD1
N
 O3'
OP1
O
3pnc 1 Q9UGP5 97.6 0.0 X-RAY
 2011-02-02 LEU A:19 A:260 0.0 0.0 H -65.7 -34.8 0.0 0.0 0.0 DG
DC
HOH
 8.901
9.120
7.060
 CD2
CD1
N
 O3'
OP1
O
3upq 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 LEU A:19 A:260 4.0 0.024 H -67.0 -39.8 4.0 0.024 0.0 DG
DC
 8.606
8.983
 CD2
CD1
 OP1
OP1
3uq0 1 Q9UGP5 97.6 0.0 X-RAY
 2012-05-23 LEU A:19 A:260 0.0 0.0 H -67.8 -39.1 0.0 0.0 0.0 DG
DC
HOH
 8.408
8.820
9.621
 CD2
CD1
O
 O5'
OP1
O
3uq2 1 Q9UGP5 97.31 0.0 X-RAY
 2012-05-23 LEU A:19 A:260 0.0 0.0 H -71.8 -39.3 0.0 0.0 0.0 DG
DC
HOH
 8.304
9.312
8.101
 CD2
CD1
O
 O5'
OP1
O
4fo6 1 Q9UGP5 97.31 0.0 X-RAY
 2012-07-11 LEU A:19 A:260 0.0 0.0 H -64.9 -34.4 0.0 0.0 0.0 DG
DC
HOH
 7.835
9.048
7.886
 CD2
CD1
O
 OP1
OP1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugp5-f1 1 Q9UGP5 100.0 0.0 LEU A:260 A:260 0.0 0.0 H -68.0 -32.5