Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 115481449 | . | C | A | CCDS7580.1:NM_033338.5:c.386gCg>gAg_NP_203124.1:p.129A>E | Homo sapiens caspase 7 (CASP7), transcript variant a, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5v6u | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | ALA | A:96 | A:96 | 19.0 | 0.165 | H | -66.6 | -43.5 | 19.0 | 0.165 | 0.0 |
HOH |
3.199 |
O |
O |
||
ALA | B:96 | B:96 | 35.0 | 0.304 | H | -59.0 | -43.2 | 35.0 | 0.304 | 0.0 |
HOH |
9.480 |
N |
O |
|||||||||
5v6z | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2018-03-21 | ALA | A:96 | A:96 | 36.0 | 0.313 | H | -61.7 | -47.0 | 36.0 | 0.313 | 0.0 |
HOH |
9.958 |
N |
O |
||
ALA | B:96 | B:96 | 27.0 | 0.235 | H | -73.6 | -32.9 | 27.0 | 0.235 | 0.0 |
HOH |
3.483 |
CA |
O |
|||||||||
4fdl | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2012-08-01 | ALA | A:98 | A:96 | 28.0 | 0.243 | H | -63.7 | -38.4 | 28.0 | 0.243 | 0.0 |
HOH |
5.344 |
N |
O |
||
ALA | B:98 | B:96 | 36.0 | 0.313 | H | -65.3 | -47.3 | 36.0 | 0.313 | 0.0 |
HOH |
6.903 |
N |
O |
|||||||||
1kmc | 1 | P55210 | 99.67 | 0.0 |
X-RAY |
2002-01-16 | ALA | A:96 | A:188 | 30.0 | 0.261 | H | -64.5 | -41.3 | 30.0 | 0.261 | 0.0 |
HOH |
6.711 |
O |
O |
||
ALA | B:96 | B:188 | 30.0 | 0.261 | H | -63.9 | -41.3 | 30.0 | 0.261 | 0.0 |
HOH |
9.228 |
N |
O |
|||||||||
1f1j | 1 | P55210 | 99.67 | 0.0 |
X-RAY |
2001-05-23 | ALA | A:98 | A:96 | 37.0 | 0.322 | H | -62.8 | -51.9 | 37.0 | 0.322 | 0.0 |
SO4 HOH |
8.927 3.484 |
N O |
O1 O |
||
ALA | B:98 | B:396 | 32.0 | 0.278 | H | -54.8 | -43.5 | NA | NA | NA | |||||||||||||
3r5k | 1 | P55210 | 99.01 | 0.0 |
X-RAY |
2011-06-29 | ALA | A:96 | A:96 | 31.0 | 0.27 | H | -50.4 | -50.1 | 31.0 | 0.27 | 0.0 |
FMT HOH |
8.992 3.817 |
N CB |
O1 O |
||
ALA | B:96 | B:396 | 30.0 | 0.261 | H | -64.2 | -33.9 | 30.0 | 0.261 | 0.0 |
HOH |
3.646 |
N |
O |
|||||||||
1i4o | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2001-03-21 | ALA | A:73 | A:96 | 24.0 | 0.209 | H | -68.8 | -49.0 | 24.0 | 0.209 | 0.0 |
HOH |
3.371 |
N |
O |
||
ALA | B:73 | B:96 | 29.0 | 0.252 | H | -58.4 | -46.3 | NA | NA | NA | |||||||||||||
1gqf | 1 | P55210 | 99.61 | 0.0 |
X-RAY |
2002-01-04 | ALA | A:50 | A:188 | 26.0 | 0.226 | H | -65.5 | -39.1 | 26.0 | 0.226 | 0.0 | ||||||
ALA | B:50 | B:188 | 37.0 | 0.322 | H | -68.4 | -38.5 | 37.0 | 0.322 | 0.0 |
SO4 HOH |
8.938 9.345 |
N CB |
O3 O |
|||||||||
1shj | 1 | P55210 | 99.61 | 0.0 |
X-RAY |
2004-08-17 | ALA | A:47 | A:96 | 35.0 | 0.304 | H | -44.0 | -46.5 | 35.0 | 0.304 | 0.0 | ||||||
ALA | B:47 | B:96 | 21.0 | 0.183 | H | -59.3 | -44.9 | 21.0 | 0.183 | 0.0 |
SO4 |
9.334 |
N |
O1 |
|||||||||
4hq0 | 1 | P55210 | 97.34 | 0.0 |
X-RAY |
2013-09-11 | ALA | A:51 | A:96 | 36.0 | 0.313 | H | -58.2 | -49.5 | 36.0 | 0.313 | 0.0 | ||||||
ALA | B:51 | B:96 | 24.0 | 0.209 | H | -64.8 | -39.9 | 24.0 | 0.209 | 0.0 | |||||||||||||
4hqr | 1 | P55210 | 97.34 | 0.0 |
X-RAY |
2013-09-11 | ALA | A:51 | A:96 | 35.0 | 0.304 | H | -63.6 | -36.4 | 35.0 | 0.304 | 0.0 | ||||||
ALA | B:51 | B:96 | 37.0 | 0.322 | H | -66.9 | -33.3 | 37.0 | 0.322 | 0.0 | |||||||||||||
1k86 | 1 | P55210 | 99.6 | 0.0 |
X-RAY |
2001-11-21 | ALA | A:46 | A:96 | 35.0 | 0.304 | H | -60.5 | -47.9 | 35.0 | 0.304 | 0.0 | ||||||
ALA | B:46 | B:96 | 38.0 | 0.33 | H | -70.3 | -49.7 | 38.0 | 0.33 | 0.0 |
HOH |
4.211 |
CB |
O |
|||||||||
3h1p | 1 | P55210 | 99.21 | 0.0 |
X-RAY |
2009-06-30 | ALA | A:47 | A:96 | 37.0 | 0.322 | H | -69.6 | -39.3 | 37.0 | 0.322 | 0.0 |
HOH |
9.328 |
N |
O |
||
ALA | B:47 | B:96 | 36.0 | 0.313 | H | -68.3 | -38.0 | 36.0 | 0.313 | 0.0 |
HOH |
3.567 |
CB |
O |
|||||||||
1k88 | 1 | P55210 | 99.21 | 0.0 |
X-RAY |
2001-11-21 | ALA | A:46 | A:96 | 32.0 | 0.278 | H | -51.4 | -48.1 | 32.0 | 0.278 | 0.0 |
HOH |
2.654 |
O |
O |
||
ALA | B:46 | B:96 | 20.0 | 0.174 | H | -65.3 | -49.9 | 20.0 | 0.174 | 0.0 |
HOH |
7.687 |
N |
O |
|||||||||
4fea | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2012-08-01 | ALA | A:40 | A:96 | 35.0 | 0.304 | H | -79.0 | -35.6 | 35.0 | 0.304 | 0.0 | ||||||
ALA | B:40 | B:96 | 35.0 | 0.304 | H | -62.0 | -52.8 | 35.0 | 0.304 | 0.0 | |||||||||||||
4jj8 | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:40 | A:96 | 22.0 | 0.191 | H | -55.5 | -45.5 | 22.0 | 0.191 | 0.0 | ||||||
ALA | B:40 | B:96 | 32.0 | 0.278 | H | -56.1 | -46.7 | NA | NA | NA | |||||||||||||
4jr1 | 1 | P55210 | 99.6 | 0.0 |
X-RAY |
2013-05-08 | ALA | A:43 | A:96 | 42.0 | 0.365 | H | -66.0 | -42.5 | 42.0 | 0.365 | 0.0 |
HOH |
3.584 |
N |
O |
||
ALA | B:43 | B:96 | 41.0 | 0.357 | H | -67.3 | -38.0 | 41.0 | 0.357 | 0.0 |
HOH |
2.954 |
O |
O |
|||||||||
4jr2 | 1 | P55210 | 99.6 | 0.0 |
X-RAY |
2013-05-08 | ALA | A:43 | A:96 | 25.0 | 0.217 | H | -57.6 | -47.9 | 25.0 | 0.217 | 0.0 |
HOH |
2.987 |
O |
O |
||
ALA | B:43 | B:96 | 23.0 | 0.2 | H | -63.6 | -42.6 | 23.0 | 0.2 | 0.0 |
HOH |
2.937 |
O |
O |
|||||||||
1shl | 1 | P55210 | 95.55 | 1e-177 |
X-RAY |
2004-08-17 | ALA | A:40 | A:96 | 34.0 | 0.296 | H | -57.6 | -47.7 | 34.0 | 0.296 | 0.0 | ||||||
ALA | B:40 | B:96 | 33.0 | 0.287 | H | -57.1 | -42.7 | 33.0 | 0.287 | 0.0 | |||||||||||||
4zvo | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ALA | A:96 | A:96 | 53.0 | 0.461 | H | -70.1 | -39.1 | 29.0 | 0.252 | 0.209 |
B:P55210:0.209 |
|||||
ALA | C:96 | C:396 | 65.0 | 0.565 | H | -72.1 | -36.8 | 20.0 | 0.174 | 0.391 |
D:P55210:0.391 |
||||||||||||
4zvp | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ALA | A:96 | A:96 | 54.0 | 0.47 | H | -66.8 | -38.4 | 37.0 | 0.322 | 0.148 |
B:P55210:0.148 |
|||||
ALA | C:96 | C:396 | 58.0 | 0.504 | H | -69.2 | -37.6 | 36.0 | 0.313 | 0.191 |
D:P55210:0.191 |
HOH |
4.768 |
CB |
O |
||||||||
4zvq | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ALA | A:96 | A:96 | 51.0 | 0.443 | H | -63.8 | -40.7 | 34.0 | 0.296 | 0.147 |
B:P55210:0.148 |
HOH |
3.458 |
N |
O |
|
ALA | C:96 | C:396 | 57.0 | 0.496 | H | -65.7 | -41.6 | 32.0 | 0.278 | 0.218 |
D:P55210:0.217 |
HOH |
4.272 |
CB |
O |
||||||||
4zvr | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ALA | A:96 | A:96 | 58.0 | 0.504 | H | -68.6 | -39.2 | 22.0 | 0.191 | 0.313 |
B:P55210:0.313 |
HOH |
3.211 |
CB |
O |
|
ALA | C:96 | C:396 | 61.0 | 0.53 | H | -68.1 | -36.6 | 17.0 | 0.148 | 0.382 |
D:P55210:0.383 |
HOH |
2.869 |
O |
O |
||||||||
4zvs | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ALA | A:96 | A:96 | 54.0 | 0.47 | H | -64.2 | -41.0 | 38.0 | 0.33 | 0.14 |
B:P55210:0.139 |
HOH |
6.718 |
CB |
O |
|
ALA | C:96 | C:396 | 54.0 | 0.47 | H | -64.6 | -40.1 | 33.0 | 0.287 | 0.183 |
D:P55210:0.183 |
HOH |
3.861 |
N |
O |
||||||||
4zvt | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ALA | A:96 | A:96 | 54.0 | 0.47 | H | -67.3 | -36.1 | 31.0 | 0.27 | 0.2 |
B:P55210:0.2 |
|||||
ALA | C:96 | C:396 | 55.0 | 0.478 | H | -69.2 | -36.4 | 31.0 | 0.27 | 0.208 |
D:P55210:0.209 |
||||||||||||
4zvu | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ALA | A:96 | A:96 | 52.0 | 0.452 | H | -64.4 | -41.3 | 35.0 | 0.304 | 0.148 |
B:P55210:0.148 |
HOH |
3.721 |
N |
O |
|
ALA | C:96 | C:396 | 45.0 | 0.391 | H | -65.4 | -42.2 | 25.0 | 0.217 | 0.174 |
D:P55210:0.174 |
||||||||||||
5ic6 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-07-20 | ALA | A:96 | A:96 | 50.0 | 0.435 | H | -62.5 | -48.2 | 35.0 | 0.304 | 0.131 |
B:P55210:0.13 |
|||||
ALA | C:96 | C:96 | 57.0 | 0.496 | H | -63.9 | -48.7 | NA | NA | NA | |||||||||||||
5k20 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2017-01-11 | ALA | A:96 | A:96 | 53.0 | 0.461 | H | -71.0 | -36.0 | 36.0 | 0.313 | 0.148 |
B:P55210:0.148 |
FMT |
9.142 |
N |
O2 |
|
ALA | C:96 | C:396 | 56.0 | 0.487 | H | -67.9 | -34.2 | 36.0 | 0.313 | 0.174 |
D:P55210:0.174 |
FMT HOH |
9.061 2.731 |
N O |
O1 O |
||||||||
6cl1 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2019-03-06 | ALA | A:96 | A:96 | 56.0 | 0.487 | H | -66.0 | -43.7 | 32.0 | 0.278 | 0.209 |
B:P55210:0.209 |
HOH |
6.981 |
O |
O |
|
ALA | C:96 | C:96 | 55.0 | 0.478 | H | -69.4 | -42.5 | 32.0 | 0.278 | 0.2 |
D:P55210:0.2 |
HOH |
7.129 |
O |
O |
||||||||
6cl2 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2019-03-06 | ALA | A:96 | A:96 | 57.0 | 0.496 | H | -66.4 | -41.9 | 38.0 | 0.33 | 0.166 |
B:P55210:0.165 |
HOH |
7.185 |
O |
O |
|
ALA | C:96 | C:96 | 54.0 | 0.47 | H | -71.0 | -30.5 | 34.0 | 0.296 | 0.174 |
D:P55210:0.174 |
HOH |
4.188 |
CB |
O |
||||||||
6x8j | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2021-06-02 | ALA | A:96 | A:96 | 55.0 | 0.478 | H | -72.9 | -35.0 | 38.0 | 0.33 | 0.148 |
B:P55210:0.148 |
HOH |
3.657 |
N |
O |
|
ALA | C:96 | B:96 | 54.0 | 0.47 | H | -67.9 | -38.2 | 39.0 | 0.339 | 0.131 |
D:P55210:0.13 |
||||||||||||
6x8l | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2021-06-02 | ALA | A:96 | A:96 | 57.0 | 0.496 | H | -64.5 | -37.3 | 40.0 | 0.348 | 0.148 |
B:P55210:0.148 |
HOH |
4.059 |
CB |
O |
|
ALA | C:96 | B:96 | 55.0 | 0.478 | H | -62.5 | -47.1 | 39.0 | 0.339 | 0.139 |
D:P55210:0.139 |
HOH |
4.033 |
CB |
O |
||||||||
4jb8 | 1 | P55210 | 100.0 | 1e-128 |
X-RAY |
2013-08-21 | ALA | A:73 | A:96 | 58.0 | 0.504 | H | -61.4 | -45.3 | 38.0 | 0.33 | 0.174 |
B:P55210:0.174 |
HOH |
2.764 |
O |
O |
|
4lsz | 1 | P55210 | 100.0 | 1e-128 |
X-RAY |
2014-07-02 | ALA | A:73 | A:96 | 55.0 | 0.478 | H | -65.2 | -41.8 | 37.0 | 0.322 | 0.156 |
B:P55210:0.157 |
HOH |
3.008 |
O |
O |
|
ALA | C:73 | C:96 | 56.0 | 0.487 | H | -65.1 | -39.4 | 39.0 | 0.339 | 0.148 |
D:P55210:0.148 |
HOH |
5.669 |
CB |
O |
||||||||
2ql5 | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ALA | A:73 | A:96 | 56.0 | 0.487 | H | -62.9 | -44.9 | 40.0 | 0.348 | 0.139 |
B:P55210:0.139 |
HOH |
3.544 |
CA |
O |
|
ALA | C:73 | C:396 | 60.0 | 0.522 | H | -61.1 | -41.0 | 40.0 | 0.348 | 0.174 |
D:P55210:0.174 |
HOH |
3.486 |
N |
O |
||||||||
2ql7 | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ALA | A:73 | A:96 | 56.0 | 0.487 | H | -63.7 | -44.5 | 39.0 | 0.339 | 0.148 |
B:P55210:0.148 |
HOH |
3.746 |
N |
O |
|
ALA | C:73 | C:396 | 59.0 | 0.513 | H | -63.1 | -41.8 | 35.0 | 0.304 | 0.209 |
D:P55210:0.209 |
HOH |
2.740 |
O |
O |
||||||||
2ql9 | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ALA | A:73 | A:96 | 57.0 | 0.496 | H | -64.9 | -36.2 | 40.0 | 0.348 | 0.148 |
B:P55210:0.148 |
HOH |
2.933 |
O |
O |
|
ALA | C:73 | C:396 | 57.0 | 0.496 | H | -65.8 | -38.8 | 33.0 | 0.287 | 0.209 |
D:P55210:0.209 |
HOH |
2.752 |
O |
O |
||||||||
2qlb | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ALA | A:73 | A:96 | 53.0 | 0.461 | H | -65.1 | -45.3 | 35.0 | 0.304 | 0.157 |
B:P55210:0.157 |
HOH |
3.046 |
O |
O |
|
ALA | C:73 | C:396 | 59.0 | 0.513 | H | -61.0 | -44.9 | 38.0 | 0.33 | 0.183 |
D:P55210:0.183 |
HOH |
2.784 |
O |
O |
||||||||
2qlf | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ALA | A:73 | A:96 | 54.0 | 0.47 | H | -62.0 | -40.8 | 38.0 | 0.33 | 0.14 |
B:P55210:0.139 |
HOH |
5.772 |
N |
O |
|
ALA | C:73 | C:396 | 57.0 | 0.496 | H | -67.5 | -34.9 | 36.0 | 0.313 | 0.183 |
D:P55210:0.183 |
HOH |
4.109 |
CB |
O |
||||||||
2qlj | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ALA | A:73 | A:96 | 56.0 | 0.487 | H | -64.0 | -42.7 | 37.0 | 0.322 | 0.165 |
B:P55210:0.165 |
HOH |
4.497 |
CB |
O |
|
ALA | C:73 | C:396 | 58.0 | 0.504 | H | -59.3 | -49.4 | 38.0 | 0.33 | 0.174 |
D:P55210:0.174 |
HOH |
3.993 |
CB |
O |
||||||||
3edr | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2008-10-28 | ALA | A:73 | A:96 | 55.0 | 0.478 | H | -63.9 | -47.8 | 37.0 | 0.322 | 0.156 |
B:P55210:0.157 |
HOH |
3.519 |
CB |
O |
|
ALA | C:73 | C:396 | 56.0 | 0.487 | H | -60.1 | -44.4 | 36.0 | 0.313 | 0.174 |
D:P55210:0.174 |
HOH |
4.049 |
CB |
O |
||||||||
3ibc | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2009-09-01 | ALA | A:73 | A:96 | 47.0 | 0.409 | H | -60.8 | -45.0 | 27.0 | 0.235 | 0.174 |
B:P55210:0.174 |
HOH |
4.171 |
CB |
O |
|
ALA | C:73 | C:396 | 58.0 | 0.504 | H | -64.6 | -55.7 | 39.0 | 0.339 | 0.165 |
D:P55210:0.165 |
HOH |
4.261 |
CB |
O |
||||||||
3ibf | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2009-09-01 | ALA | A:73 | A:96 | 53.0 | 0.461 | H | -57.1 | -43.7 | 36.0 | 0.313 | 0.148 |
B:P55210:0.148 |
HOH |
9.772 |
N |
O |
|
ALA | C:73 | C:396 | 59.0 | 0.513 | H | -61.5 | -43.7 | 37.0 | 0.322 | 0.191 |
D:P55210:0.191 |
HOH |
3.884 |
CB |
O |
||||||||
1i51 | 1 | P55210 | 99.32 | 6e-107 |
X-RAY |
2002-02-23 | ALA | A:46 | A:96 | 56.0 | 0.487 | H | -69.4 | -45.8 | 32.0 | 0.278 | 0.209 |
B:P55210:0.209 |
|||||
ALA | C:46 | C:96 | 55.0 | 0.478 | H | -63.4 | -49.0 | 35.0 | 0.304 | 0.174 |
D:P55210:0.174 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p55210-f1 | 1 | P55210 | 100.0 | 0.0 | ALA | A:96 | A:96 | 23.0 | 0.2 | H | -61.7 | -47.2 |