Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 115481467 | . | G | A | CCDS7580.1:NM_033338.5:c.404cGa>cAa_NP_203124.1:p.135R>Q | Homo sapiens caspase 7 (CASP7), transcript variant a, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5v6u | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | ARG | A:102 | A:102 | 120.0 | 0.533 | H | -68.2 | -48.8 | 120.0 | 0.533 | 0.0 |
HOH |
5.267 |
NH2 |
O |
||
ARG | B:102 | B:102 | 142.0 | 0.631 | H | -62.4 | -49.2 | 142.0 | 0.631 | 0.0 |
HOH |
2.640 |
O |
O |
|||||||||
5v6z | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2018-03-21 | ARG | A:102 | A:102 | 116.0 | 0.516 | H | -69.6 | -46.5 | 116.0 | 0.516 | 0.0 |
HOH |
2.661 |
NH2 |
O |
||
ARG | B:102 | B:102 | 139.0 | 0.618 | H | -67.6 | -46.4 | 139.0 | 0.618 | 0.0 |
HOH |
2.485 |
O |
O |
|||||||||
4fdl | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2012-08-01 | ARG | A:104 | A:102 | 111.0 | 0.493 | H | -67.4 | -53.7 | 111.0 | 0.493 | 0.0 |
HOH |
8.734 |
CB |
O |
||
ARG | B:104 | B:102 | 144.0 | 0.64 | H | -62.9 | -49.2 | 144.0 | 0.64 | 0.0 |
HOH |
3.672 |
O |
O |
|||||||||
1kmc | 1 | P55210 | 99.67 | 0.0 |
X-RAY |
2002-01-16 | ARG | A:102 | A:194 | 139.0 | 0.618 | H | -66.2 | -50.0 | 139.0 | 0.618 | 0.0 |
HOH |
2.941 |
NH1 |
O |
||
ARG | B:102 | B:194 | 140.0 | 0.622 | H | -67.2 | -49.9 | 140.0 | 0.622 | 0.0 | |||||||||||||
1f1j | 1 | P55210 | 99.67 | 0.0 |
X-RAY |
2001-05-23 | ARG | A:104 | A:102 | 108.0 | 0.48 | H | -68.7 | -47.7 | 108.0 | 0.48 | 0.0 |
HOH |
2.858 |
O |
O |
||
ARG | B:104 | B:402 | 130.0 | 0.578 | H | -70.3 | -46.9 | NA | NA | NA | |||||||||||||
3r5k | 1 | P55210 | 99.01 | 0.0 |
X-RAY |
2011-06-29 | ARG | A:102 | A:102 | 117.0 | 0.52 | H | -66.2 | -49.0 | 117.0 | 0.52 | 0.0 |
HOH |
4.803 |
NH1 |
O |
||
ARG | B:102 | B:402 | 141.0 | 0.627 | H | -66.2 | -41.0 | 141.0 | 0.627 | 0.0 |
HOH |
8.865 |
NH2 |
O |
|||||||||
1i4o | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2001-03-21 | ARG | A:79 | A:102 | 117.0 | 0.52 | H | -73.3 | -45.5 | 117.0 | 0.52 | 0.0 |
HOH |
2.888 |
NH2 |
O |
||
ARG | B:79 | B:102 | 136.0 | 0.604 | H | -67.8 | -52.6 | NA | NA | NA | |||||||||||||
1gqf | 1 | P55210 | 99.61 | 0.0 |
X-RAY |
2002-01-04 | ARG | A:56 | A:194 | 118.0 | 0.524 | H | -65.3 | -46.6 | 118.0 | 0.524 | 0.0 | ||||||
ARG | B:56 | B:194 | 118.0 | 0.524 | H | -68.2 | -50.4 | 118.0 | 0.524 | 0.0 | |||||||||||||
1shj | 1 | P55210 | 99.61 | 0.0 |
X-RAY |
2004-08-17 | ARG | A:53 | A:102 | 123.0 | 0.547 | H | -69.0 | -41.9 | 123.0 | 0.547 | 0.0 | ||||||
ARG | B:53 | B:102 | 136.0 | 0.604 | H | -65.1 | -44.8 | 136.0 | 0.604 | 0.0 | |||||||||||||
4hq0 | 1 | P55210 | 97.34 | 0.0 |
X-RAY |
2013-09-11 | ARG | A:57 | A:102 | 112.0 | 0.498 | H | -64.0 | -35.6 | 112.0 | 0.498 | 0.0 | ||||||
ARG | B:57 | B:102 | 137.0 | 0.609 | H | -62.0 | -43.9 | 137.0 | 0.609 | 0.0 | |||||||||||||
4hqr | 1 | P55210 | 97.34 | 0.0 |
X-RAY |
2013-09-11 | ARG | A:57 | A:102 | 114.0 | 0.507 | H | -74.0 | -35.4 | 114.0 | 0.507 | 0.0 | ||||||
ARG | B:57 | B:102 | 142.0 | 0.631 | H | -74.9 | -37.7 | 142.0 | 0.631 | 0.0 | |||||||||||||
1k86 | 1 | P55210 | 99.6 | 0.0 |
X-RAY |
2001-11-21 | ARG | A:52 | A:102 | 116.0 | 0.516 | H | -62.8 | -47.8 | 116.0 | 0.516 | 0.0 |
HOH |
2.700 |
NH2 |
O |
||
ARG | B:52 | B:102 | 138.0 | 0.613 | H | -76.1 | -42.9 | 138.0 | 0.613 | 0.0 |
HOH |
7.475 |
NH2 |
O |
|||||||||
3h1p | 1 | P55210 | 99.21 | 0.0 |
X-RAY |
2009-06-30 | ARG | A:53 | A:102 | 111.0 | 0.493 | H | -67.7 | -46.3 | 111.0 | 0.493 | 0.0 |
HOH |
5.372 |
NH2 |
O |
||
ARG | B:53 | B:102 | 134.0 | 0.596 | H | -63.6 | -49.4 | 134.0 | 0.596 | 0.0 |
HOH |
2.603 |
NH1 |
O |
|||||||||
1k88 | 1 | P55210 | 99.21 | 0.0 |
X-RAY |
2001-11-21 | ARG | A:52 | A:102 | 120.0 | 0.533 | H | -62.3 | -46.0 | 120.0 | 0.533 | 0.0 |
HOH |
2.833 |
NH1 |
O |
||
ARG | B:52 | B:102 | 140.0 | 0.622 | H | -65.2 | -48.2 | 140.0 | 0.622 | 0.0 |
HOH |
2.607 |
NH1 |
O |
|||||||||
4fea | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2012-08-01 | ARG | A:46 | A:102 | 135.0 | 0.6 | H | -66.0 | -23.2 | 135.0 | 0.6 | 0.0 | ||||||
ARG | B:46 | B:102 | 130.0 | 0.578 | H | -57.4 | -45.3 | 130.0 | 0.578 | 0.0 | |||||||||||||
4jj8 | 1 | P55210 | 100.0 | 0.0 |
X-RAY |
2013-06-12 | ARG | A:46 | A:102 | 115.0 | 0.511 | H | -66.4 | -43.9 | 115.0 | 0.511 | 0.0 |
HOH |
4.787 |
NH2 |
O |
||
ARG | B:46 | B:102 | 140.0 | 0.622 | H | -66.2 | -43.6 | NA | NA | NA | |||||||||||||
4jr1 | 1 | P55210 | 99.6 | 0.0 |
X-RAY |
2013-05-08 | ARG | A:49 | A:102 | 106.0 | 0.471 | H | -65.1 | -33.4 | 106.0 | 0.471 | 0.0 |
HOH |
2.748 |
O |
O |
||
ARG | B:49 | B:102 | 132.0 | 0.587 | H | -69.3 | -33.1 | 132.0 | 0.587 | 0.0 |
HOH |
3.292 |
CG |
O |
|||||||||
4jr2 | 1 | P55210 | 99.6 | 0.0 |
X-RAY |
2013-05-08 | ARG | A:49 | A:102 | 108.0 | 0.48 | H | -64.1 | -38.3 | 108.0 | 0.48 | 0.0 |
HOH |
2.753 |
O |
O |
||
ARG | B:49 | B:102 | 140.0 | 0.622 | H | -61.8 | -37.7 | 140.0 | 0.622 | 0.0 |
HOH |
2.513 |
NE |
O |
|||||||||
1shl | 1 | P55210 | 95.55 | 1e-177 |
X-RAY |
2004-08-17 | ARG | A:46 | A:102 | 121.0 | 0.538 | H | -67.8 | -39.9 | 121.0 | 0.538 | 0.0 | ||||||
ARG | B:46 | B:102 | 137.0 | 0.609 | H | -59.5 | -44.3 | 137.0 | 0.609 | 0.0 | |||||||||||||
4zvo | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ARG | A:102 | A:102 | 110.0 | 0.489 | H | -66.9 | -43.7 | 110.0 | 0.489 | 0.0 |
HOH |
9.857 |
NH2 |
O |
||
ARG | C:102 | C:402 | 155.0 | 0.689 | H | -65.7 | -42.0 | 155.0 | 0.689 | 0.0 | |||||||||||||
4zvp | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ARG | A:102 | A:102 | 108.0 | 0.48 | H | -66.8 | -42.4 | 108.0 | 0.48 | 0.0 |
HOH |
5.219 |
NH2 |
O |
||
ARG | C:102 | C:402 | 139.0 | 0.618 | H | -65.5 | -40.7 | 139.0 | 0.618 | 0.0 |
HOH |
2.692 |
NH1 |
O |
|||||||||
4zvq | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ARG | A:102 | A:102 | 107.0 | 0.476 | H | -68.0 | -41.9 | 107.0 | 0.476 | 0.0 |
HOH |
5.070 |
NH2 |
O |
||
ARG | C:102 | C:402 | 141.0 | 0.627 | H | -67.1 | -40.2 | 141.0 | 0.627 | 0.0 |
HOH |
2.678 |
NH1 |
O |
|||||||||
4zvr | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ARG | A:102 | A:102 | 108.0 | 0.48 | H | -63.2 | -43.7 | 108.0 | 0.48 | 0.0 |
HOH |
2.684 |
NH2 |
O |
||
ARG | C:102 | C:402 | 144.0 | 0.64 | H | -62.0 | -45.4 | 144.0 | 0.64 | 0.0 |
HOH |
3.980 |
CG |
O |
|||||||||
4zvs | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ARG | A:102 | A:102 | 108.0 | 0.48 | H | -63.8 | -42.6 | 108.0 | 0.48 | 0.0 |
HOH |
5.118 |
NH2 |
O |
||
ARG | C:102 | C:402 | 139.0 | 0.618 | H | -63.6 | -41.8 | 139.0 | 0.618 | 0.0 |
HOH |
2.768 |
NH1 |
O |
|||||||||
4zvt | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ARG | A:102 | A:102 | 110.0 | 0.489 | H | -64.6 | -44.8 | 110.0 | 0.489 | 0.0 | ||||||
ARG | C:102 | C:402 | 137.0 | 0.609 | H | -64.2 | -44.1 | 137.0 | 0.609 | 0.0 | |||||||||||||
4zvu | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-04-20 | ARG | A:102 | A:102 | 107.0 | 0.476 | H | -63.2 | -44.4 | 107.0 | 0.476 | 0.0 |
HOH |
5.272 |
NH2 |
O |
||
ARG | C:102 | C:402 | 150.0 | 0.667 | H | -62.9 | -43.4 | 150.0 | 0.667 | 0.0 |
HOH |
4.002 |
CG |
O |
|||||||||
5ic6 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2016-07-20 | ARG | A:102 | A:102 | 141.0 | 0.627 | H | -76.1 | -29.0 | 141.0 | 0.627 | 0.0 | ||||||
ARG | C:102 | C:102 | 117.0 | 0.52 | H | -75.1 | -31.6 | NA | NA | NA | |||||||||||||
5k20 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2017-01-11 | ARG | A:102 | A:102 | 111.0 | 0.493 | H | -67.5 | -42.9 | 111.0 | 0.493 | 0.0 |
HOH |
4.423 |
NH2 |
O |
||
ARG | C:102 | C:402 | 139.0 | 0.618 | H | -65.6 | -45.6 | 139.0 | 0.618 | 0.0 |
HOH |
2.880 |
NE |
O |
|||||||||
6cl1 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2019-03-06 | ARG | A:102 | A:102 | 116.0 | 0.516 | H | -66.0 | -47.5 | 116.0 | 0.516 | 0.0 |
HOH |
4.552 |
NH2 |
O |
||
ARG | C:102 | C:102 | 139.0 | 0.618 | H | -62.6 | -45.8 | 139.0 | 0.618 | 0.0 |
HOH |
2.801 |
NE |
O |
|||||||||
6cl2 | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2019-03-06 | ARG | A:102 | A:102 | 110.0 | 0.489 | H | -68.6 | -45.0 | 110.0 | 0.489 | 0.0 |
HOH |
4.405 |
CB |
O |
||
ARG | C:102 | C:102 | 152.0 | 0.676 | H | -68.4 | -45.3 | 152.0 | 0.676 | 0.0 |
HOH |
2.908 |
NE |
O |
|||||||||
6x8j | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2021-06-02 | ARG | A:102 | A:102 | 144.0 | 0.64 | H | -72.7 | -35.6 | 144.0 | 0.64 | 0.0 |
HOH |
2.657 |
NH1 |
O |
||
ARG | C:102 | B:102 | 112.0 | 0.498 | H | -63.2 | -41.2 | 112.0 | 0.498 | 0.0 |
HOH |
2.360 |
NH2 |
O |
|||||||||
6x8l | 1 | P55210 | 100.0 | 1e-146 |
X-RAY |
2021-06-02 | ARG | A:102 | A:102 | 141.0 | 0.627 | H | -63.9 | -41.7 | 141.0 | 0.627 | 0.0 |
HOH |
2.629 |
O |
O |
||
ARG | C:102 | B:102 | 108.0 | 0.48 | H | -58.2 | -48.3 | 108.0 | 0.48 | 0.0 |
HOH |
5.525 |
NH2 |
O |
|||||||||
4jb8 | 1 | P55210 | 100.0 | 1e-128 |
X-RAY |
2013-08-21 | ARG | A:79 | A:102 | 163.0 | 0.724 | H | -66.3 | -38.0 | 44.0 | 0.196 | 0.528 |
C:None:0.529 |
HOH |
3.606 |
NH2 |
O |
|
4lsz | 1 | P55210 | 100.0 | 1e-128 |
X-RAY |
2014-07-02 | ARG | A:79 | A:102 | 145.0 | 0.644 | H | -67.1 | -37.8 | 95.0 | 0.422 | 0.222 |
E:None:0.222 |
HOH |
2.927 |
NE |
O |
|
ARG | C:79 | C:102 | 142.0 | 0.631 | H | -64.3 | -40.2 | 105.0 | 0.467 | 0.164 |
F:None:0.164 |
HOH |
2.694 |
NH2 |
O |
||||||||
2ql5 | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ARG | A:79 | A:102 | 114.0 | 0.507 | H | -72.6 | -45.4 | 114.0 | 0.507 | 0.0 |
HOH |
3.059 |
NH1 |
O |
||
ARG | C:79 | C:402 | 134.0 | 0.596 | H | -68.8 | -42.5 | 134.0 | 0.596 | 0.0 |
HOH |
2.744 |
NH1 |
O |
|||||||||
2ql7 | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ARG | A:79 | A:102 | 110.0 | 0.489 | H | -66.5 | -45.4 | 110.0 | 0.489 | 0.0 |
HOH |
3.163 |
NH1 |
O |
||
ARG | C:79 | C:402 | 135.0 | 0.6 | H | -73.4 | -41.9 | 135.0 | 0.6 | 0.0 |
HOH |
2.725 |
NH1 |
O |
|||||||||
2ql9 | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ARG | A:79 | A:102 | 110.0 | 0.489 | H | -69.4 | -44.3 | 110.0 | 0.489 | 0.0 |
HOH |
2.941 |
NH2 |
O |
||
ARG | C:79 | C:402 | 133.0 | 0.591 | H | -72.4 | -41.1 | 133.0 | 0.591 | 0.0 |
HOH |
2.885 |
O |
O |
|||||||||
2qlb | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ARG | A:79 | A:102 | 109.0 | 0.484 | H | -68.6 | -43.2 | 109.0 | 0.484 | 0.0 |
HOH |
3.187 |
NH2 |
O |
||
ARG | C:79 | C:402 | 139.0 | 0.618 | H | -66.5 | -36.6 | 139.0 | 0.618 | 0.0 |
HOH |
2.633 |
O |
O |
|||||||||
2qlf | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ARG | A:79 | A:102 | 109.0 | 0.484 | H | -72.2 | -53.1 | 109.0 | 0.484 | 0.0 |
HOH |
3.963 |
CB |
O |
||
ARG | C:79 | C:402 | 137.0 | 0.609 | H | -65.4 | -41.4 | 137.0 | 0.609 | 0.0 |
HOH |
8.505 |
CG |
O |
|||||||||
2qlj | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2007-08-28 | ARG | A:79 | A:102 | 113.0 | 0.502 | H | -65.1 | -45.4 | 113.0 | 0.502 | 0.0 |
HOH |
4.988 |
NH2 |
O |
||
ARG | C:79 | C:402 | 135.0 | 0.6 | H | -73.6 | -36.0 | 135.0 | 0.6 | 0.0 |
HOH |
9.466 |
C |
O |
|||||||||
3edr | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2008-10-28 | ARG | A:79 | A:102 | 113.0 | 0.502 | H | -65.5 | -50.7 | 113.0 | 0.502 | 0.0 |
HOH |
4.437 |
NH2 |
O |
||
ARG | C:79 | C:402 | 140.0 | 0.622 | H | -64.6 | -43.8 | 140.0 | 0.622 | 0.0 | |||||||||||||
3ibc | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2009-09-01 | ARG | A:79 | A:102 | 113.0 | 0.502 | H | -63.5 | -42.5 | 113.0 | 0.502 | 0.0 |
HOH |
4.332 |
NH2 |
O |
||
ARG | C:79 | C:402 | 134.0 | 0.596 | H | -63.6 | -39.9 | 134.0 | 0.596 | 0.0 |
HOH |
6.064 |
CG |
O |
|||||||||
3ibf | 1 | P55210 | 100.0 | 4e-127 |
X-RAY |
2009-09-01 | ARG | A:79 | A:102 | 113.0 | 0.502 | H | -64.3 | -47.4 | 113.0 | 0.502 | 0.0 |
HOH |
5.432 |
NH2 |
O |
||
ARG | C:79 | C:402 | 138.0 | 0.613 | H | -74.7 | -39.6 | 138.0 | 0.613 | 0.0 |
HOH |
3.898 |
CG |
O |
|||||||||
1i51 | 1 | P55210 | 99.32 | 6e-107 |
X-RAY |
2002-02-23 | ARG | A:52 | A:102 | 124.0 | 0.551 | H | -69.1 | -41.1 | 124.0 | 0.551 | 0.0 | ||||||
ARG | C:52 | C:102 | 137.0 | 0.609 | H | -71.4 | -44.6 | 137.0 | 0.609 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p55210-f1 | 1 | P55210 | 100.0 | 0.0 | ARG | A:102 | A:102 | 164.0 | 0.729 | H | -65.5 | -38.7 |