Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 115485249 . G A CCDS7580.1:NM_033338.5:c.604Gat>Aat_NP_203124.1:p.202D>N Homo sapiens caspase 7 (CASP7), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5v6u 1 P55210 100.0 0.0 X-RAY
 2017-10-18 ASP A:169 A:169 74.0 0.493 T -71.9 -11.4 74.0 0.493 0.0 HOH
 5.722
 N
 O
ASP B:169 B:169 99.0 0.66 G -71.1 -5.4 99.0 0.66 0.0 8YM
HOH
 7.618
5.955
 OD1
N
 O2
O
5v6z 1 P55210 100.0 0.0 X-RAY
 2018-03-21 ASP A:169 A:169 70.0 0.467 T -76.9 -19.5 70.0 0.467 0.0 HOH
 5.608
 N
 O
ASP B:169 B:169 120.0 0.8 G -79.4 -4.5 120.0 0.8 0.0 8YJ
HOH
 8.601
5.770
 OD1
N
 OAR
O
4fdl 1 P55210 100.0 0.0 X-RAY
 2012-08-01 ASP A:171 A:169 96.0 0.64 G -72.3 -3.8 64.0 0.427 0.213 B:P55210:0.213
 HOH
 5.215
 OD2
 O
ASP B:171 B:169 74.0 0.493 T -65.0 -13.7 57.0 0.38 0.113 A:P55210:0.113
 HOH
 5.850
 N
 O
1kmc 1 P55210 99.67 0.0 X-RAY
 2002-01-16 ASP A:169 A:268 83.0 0.553 T -95.8 5.6 63.0 0.42 0.133 B:P55210:0.133
 HOH
 5.318
 N
 O
ASP B:169 B:268 84.0 0.56 T -96.7 5.4 65.0 0.433 0.127 A:P55210:0.127
 HOH
 5.499
 N
 O
1f1j 1 P55210 99.67 0.0 X-RAY
 2001-05-23 ASP A:171 A:169 81.0 0.54 T -76.8 -14.7 81.0 0.54 0.0 HOH
 3.275
 OD2
 O
ASP B:171 B:469 71.0 0.473 T -79.4 -5.5 NA NA NA
3r5k 1 P55210 99.01 0.0 X-RAY
 2011-06-29 ASP A:169 A:169 90.0 0.6 G -79.4 -4.4 66.0 0.44 0.16 B:P55210:0.16
 HOH
 5.502
 N
 O
ASP B:169 B:469 79.0 0.527 G -83.6 -4.8 58.0 0.387 0.14 A:P55210:0.14
 HOH
 5.467
 N
 O
1i4o 1 P55210 100.0 0.0 X-RAY
 2001-03-21 ASP A:146 A:169 88.0 0.587 T -98.4 8.0 88.0 0.587 0.0 HOH
 2.770
 OD2
 O
ASP B:146 B:169 85.0 0.567 T -76.4 -17.1 NA NA NA
1gqf 1 P55210 99.61 0.0 X-RAY
 2002-01-04 ASP A:123 A:268 147.0 0.98 T -34.6 -59.6 130.0 0.867 0.113 B:P55210:0.113
ASP B:123 B:268 119.0 0.793 G -63.9 28.7 104.0 0.693 0.1 A:P55210:0.1
 HOH
 7.860
 O
 O
1shj 1 P55210 99.61 0.0 X-RAY
 2004-08-17 ALA A:120 A:169 76.0 0.661 T -76.2 -45.3 76.0 0.661 0.0
ALA B:120 B:169 72.0 0.626 T -43.5 -58.3 72.0 0.626 0.0
4hq0 1 P55210 97.34 0.0 X-RAY
 2013-09-11 ASP A:124 A:169 79.0 0.527 T -73.8 -54.5 79.0 0.527 0.0
ASP B:124 B:169 80.0 0.533 G -75.8 -2.0 80.0 0.533 0.0
4hqr 1 P55210 97.34 0.0 X-RAY
 2013-09-11 ASP A:124 A:169 87.0 0.58 T -86.5 -30.5 65.0 0.433 0.147 B:P55210:0.147
ASP B:124 B:169 91.0 0.607 T -79.3 2.2 91.0 0.607 0.0
1k86 1 P55210 99.6 0.0 X-RAY
 2001-11-21 ALA A:119 A:169 63.0 0.548 G -78.3 17.3 63.0 0.548 0.0
ALA B:119 B:169 82.0 0.713 G -47.3 -52.6 58.0 0.504 0.209 A:P55210:0.209
 HOH
 5.906
 N
 O
3h1p 1 P55210 99.21 0.0 X-RAY
 2009-06-30 ASP A:120 A:169 75.0 0.5 T -82.3 -15.8 52.0 0.347 0.153 B:P55210:0.153
 HOH
 4.553
 O
 O
ASP B:120 B:169 77.0 0.513 T -75.2 -1.5 61.0 0.407 0.106 A:P55210:0.107
 HOH
 2.408
 O
 O
1k88 1 P55210 99.21 0.0 X-RAY
 2001-11-21 ALA A:119 A:169 83.0 0.722 G -49.5 -52.2 83.0 0.722 0.0 HOH
 7.425
 N
 O
ALA B:119 B:169 56.0 0.487 G -37.7 -53.5 56.0 0.487 0.0 HOH
 2.762
 N
 O
4fea 1 P55210 100.0 0.0 X-RAY
 2012-08-01 ASP A:113 A:169 131.0 0.873 T -84.2 -28.9 131.0 0.873 0.0
ASP B:113 B:169 106.0 0.707 T -76.3 -30.1 106.0 0.707 0.0
4jj8 1 P55210 100.0 0.0 X-RAY
 2013-06-12 ASP A:113 A:169 95.0 0.633 T -83.0 -4.8 95.0 0.633 0.0 HOH
 7.723
 N
 O
ASP B:113 B:169 70.0 0.467 T -79.9 -2.4 NA NA NA
4jr1 1 P55210 99.6 0.0 X-RAY
 2013-05-08 ASP A:116 A:169 19.0 0.127 T -90.3 -17.1 19.0 0.127 0.0 HOH
 5.261
 O
 O
ASP B:116 B:169 85.0 0.567 T -81.3 -7.9 85.0 0.567 0.0 HOH
 5.725
 N
 O
4jr2 1 P55210 99.6 0.0 X-RAY
 2013-05-08 ASP A:116 A:169 77.0 0.513 T -84.5 -4.9 59.0 0.393 0.12 B:P55210:0.12
 HOH
 2.737
 O
 O
ASP B:116 B:169 95.0 0.633 T -90.8 1.1 95.0 0.633 0.0 HOH
 5.462
 O
 O
1shl 1 P55210 95.55 1e-177 X-RAY
 2004-08-17 ASP A:113 A:169 96.0 0.64 T -133.6 -32.8 96.0 0.64 0.0
ASP B:113 B:169 104.0 0.693 T -70.3 -30.7 104.0 0.693 0.0
4zvo 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:169 A:169 96.0 0.64 T -74.7 -15.8 50.0 0.333 0.307 B:P55210:0.14
C:P55210:0.227
 HOH
 4.266
 O
 O
ASP C:169 C:469 102.0 0.68 T -75.2 -16.2 56.0 0.373 0.307 D:P55210:0.147
A:P55210:0.213
4zvp 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:169 A:169 104.0 0.693 T -88.4 -4.2 59.0 0.393 0.3 B:P55210:0.14
C:P55210:0.22
 HOH
 5.720
 N
 O
ASP C:169 C:469 94.0 0.627 T -90.0 -5.2 51.0 0.34 0.287 A:P55210:0.2
D:P55210:0.147
 HOH
 5.604
 N
 O
4zvq 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:169 A:169 104.0 0.693 T -86.6 -1.7 58.0 0.387 0.306 B:P55210:0.14
C:P55210:0.22
 HOH
 4.917
 OD2
 O
ASP C:169 C:469 89.0 0.593 T -87.1 -2.3 48.0 0.32 0.273 A:P55210:0.193
D:P55210:0.14
 HOH
 5.457
 N
 O
4zvr 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:169 A:169 98.0 0.653 T -84.7 -13.4 56.0 0.373 0.28 B:P55210:0.14
C:P55210:0.193
 HOH
 4.772
 OD2
 O
ASP C:169 C:469 89.0 0.593 T -83.0 -13.5 42.0 0.28 0.313 A:P55210:0.24
D:P55210:0.127
 HOH
 2.878
 OD2
 O
4zvs 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:169 A:169 105.0 0.7 T -82.2 -6.4 61.0 0.407 0.293 B:P55210:0.14
C:P55210:0.213
 HOH
 4.970
 OD2
 O
ASP C:169 C:469 96.0 0.64 T -82.9 -6.6 53.0 0.353 0.287 A:P55210:0.213
D:P55210:0.133
 HOH
 4.567
 O
 O
4zvt 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:169 A:169 112.0 0.747 G -72.8 -14.3 65.0 0.433 0.314 B:P55210:0.133
C:P55210:0.233
ASP C:169 C:469 104.0 0.693 G -73.8 -15.1 55.0 0.367 0.326 A:P55210:0.233
D:P55210:0.147
4zvu 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:169 A:169 111.0 0.74 G -74.2 -9.1 58.0 0.387 0.353 B:P55210:0.133
C:P55210:0.267
ASP C:169 C:469 94.0 0.627 T -74.7 -9.9 48.0 0.32 0.307 D:P55210:0.133
A:P55210:0.227
 HOH
 4.571
 O
 O
5ic6 1 P55210 100.0 1e-146 X-RAY
 2016-07-20 ASP A:169 A:169 110.0 0.733 T -87.7 -8.4 86.0 0.573 0.16 B:P55210:0.16
ASP C:169 C:169 97.0 0.647 T -87.5 -8.7 NA NA NA
5k20 1 P55210 100.0 1e-146 X-RAY
 2017-01-11 ASP A:169 A:169 100.0 0.667 G -75.5 -19.2 59.0 0.393 0.274 B:P55210:0.147
C:P55210:0.187
 HOH
 5.716
 N
 O
ASP C:169 C:469 99.0 0.66 G -73.6 -16.4 57.0 0.38 0.28 A:P55210:0.193
D:P55210:0.14
 HOH
 4.746
 O
 O
6cl1 1 P55210 100.0 1e-146 X-RAY
 2019-03-06 ASP A:169 A:169 119.0 0.793 G -74.8 -10.1 64.0 0.427 0.366 B:P55210:0.16
C:P55210:0.26
 HOH
 5.791
 OD2
 O
ASP C:169 C:169 86.0 0.573 G -76.4 -10.9 42.0 0.28 0.293 D:P55210:0.147
A:P55210:0.207
 HOH
 5.879
 N
 O
6cl2 1 P55210 100.0 1e-146 X-RAY
 2019-03-06 ASP A:169 A:169 111.0 0.74 G -85.3 -2.0 61.0 0.407 0.333 B:P55210:0.133
C:P55210:0.24
 HOH
 7.298
 N
 O
ASP C:169 C:169 98.0 0.653 T -80.0 -5.1 50.0 0.333 0.32 A:P55210:0.24
D:P55210:0.127
 HOH
 5.578
 N
 O
6x8j 1 P55210 100.0 1e-146 X-RAY
 2021-06-02 ASP A:169 A:169 111.0 0.74 T -84.3 -9.6 64.0 0.427 0.313 B:P55210:0.133
C:P55210:0.227
 HOH
 5.618
 N
 O
ASP C:169 B:169 112.0 0.747 T -84.9 -8.0 68.0 0.453 0.294 D:P55210:0.127
A:P55210:0.2
 HOH
 6.942
 C
 O
6x8l 1 P55210 100.0 1e-146 X-RAY
 2021-06-02 ASP A:169 A:169 112.0 0.747 G -78.5 -5.0 69.0 0.46 0.287 B:P55210:0.133
C:P55210:0.207
 HOH
 7.368
 OD1
 O
ASP C:169 B:169 113.0 0.753 T -93.1 4.7 70.0 0.467 0.286 A:P55210:0.207
D:P55210:0.133
 HOH
 5.443
 N
 O
4jb8 1 P55210 100.0 1e-128 X-RAY
 2013-08-21 ASP A:146 A:169 99.0 0.66 T -80.0 -15.8 60.0 0.4 0.26 B:P55210:0.14
A:P55210:0.173
 HOH
 4.832
 OD2
 O
4lsz 1 P55210 100.0 1e-128 X-RAY
 2014-07-02 ASP A:146 A:169 114.0 0.76 T -80.9 -9.2 68.0 0.453 0.307 B:P55210:0.14
C:P55210:0.233
 HOH
 5.401
 O
 O
ASP C:146 C:169 116.0 0.773 T -83.5 -8.8 71.0 0.473 0.3 D:P55210:0.133
A:P55210:0.22
 HOH
 4.931
 OD2
 O
2ql5 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:146 A:169 103.0 0.687 T -91.0 2.5 62.0 0.413 0.274 B:P55210:0.14
C:P55210:0.187
 HOH
 5.604
 N
 O
ASP C:146 C:469 97.0 0.647 T -92.1 -5.3 57.0 0.38 0.267 D:P55210:0.14
A:P55210:0.173
 HOH
 4.463
 O
 O
2ql7 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:146 A:169 101.0 0.673 T -97.4 4.3 59.0 0.393 0.28 B:P55210:0.133
C:P55210:0.2
 HOH
 3.089
 O
 O
ASP C:146 C:469 87.0 0.58 T -90.4 -8.8 47.0 0.313 0.267 D:P55210:0.14
A:P55210:0.187
 HOH
 2.727
 OD2
 O
2ql9 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:146 A:169 104.0 0.693 T -86.1 3.5 59.0 0.393 0.3 B:P55210:0.147
C:P55210:0.213
 HOH
 4.898
 OD2
 O
ASP C:146 C:469 90.0 0.6 T -85.6 -3.3 49.0 0.327 0.273 D:P55210:0.14
A:P55210:0.187
 HOH
 2.634
 OD2
 O
2qlb 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:146 A:169 100.0 0.667 T -97.6 7.8 59.0 0.393 0.274 B:P55210:0.127
C:P55210:0.193
 HOH
 5.012
 OD2
 O
ASP C:146 C:469 87.0 0.58 T -78.9 -12.2 50.0 0.333 0.247 D:P55210:0.14
A:P55210:0.16
 HOH
 4.772
 OD2
 O
2qlf 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:146 A:169 94.0 0.627 G -89.8 11.6 51.0 0.34 0.287 B:P55210:0.133
C:P55210:0.207
 HOH
 4.187
 OD2
 O
ASP C:146 C:469 102.0 0.68 T -73.0 -9.2 48.0 0.32 0.36 D:P55210:0.173
A:P55210:0.273
 HOH
 6.762
 C
 O
2qlj 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:146 A:169 105.0 0.7 G -75.4 5.5 60.0 0.4 0.3 B:P55210:0.14
C:P55210:0.207
 HOH
 7.268
 N
 O
ASP C:146 C:469 104.0 0.693 T -86.3 0.9 51.0 0.34 0.353 D:P55210:0.147
A:P55210:0.273
 HOH
 5.483
 N
 O
3edr 1 P55210 100.0 4e-127 X-RAY
 2008-10-28 ASP A:146 A:169 106.0 0.707 G -86.1 13.5 61.0 0.407 0.3 B:P55210:0.147
C:P55210:0.22
 HOH
 7.380
 O
 O
ASP C:146 C:469 93.0 0.62 T -76.8 -13.3 50.0 0.333 0.287 D:P55210:0.147
A:P55210:0.18
 HOH
 5.218
 O
 O
3ibc 1 P55210 100.0 4e-127 X-RAY
 2009-09-01 ASP A:146 A:169 104.0 0.693 T -75.3 1.5 61.0 0.407 0.286 B:P55210:0.133
C:P55210:0.213
 HOH
 7.494
 O
 O
ASP C:146 C:469 99.0 0.66 G -68.4 -31.6 52.0 0.347 0.313 A:P55210:0.213
D:P55210:0.153
 HOH
 5.694
 N
 O
3ibf 1 P55210 100.0 4e-127 X-RAY
 2009-09-01 ASP A:146 A:169 106.0 0.707 G -82.5 16.6 64.0 0.427 0.28 B:P55210:0.14
C:P55210:0.193
 HOH
 7.311
 N
 O
ASP C:146 C:469 90.0 0.6 T -81.4 -3.8 52.0 0.347 0.253 D:P55210:0.14
A:P55210:0.16
 HOH
 5.669
 N
 O
1i51 1 P55210 99.32 6e-107 X-RAY
 2002-02-23 ALA A:119 A:169 90.0 0.783 G -48.7 -25.3 70.0 0.609 0.174 B:P55210:0.026
C:P55210:0.157
ALA C:119 C:169 84.0 0.73 G -48.2 -28.5 65.0 0.565 0.165 A:P55210:0.157
D:P55210:0.017

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p55210-f1 1 P55210 100.0 0.0 ASP A:169 A:169 68.0 0.453 T -80.4 -20.2