Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 123310859 . C A CCDS53584.1:NM_001144915.1:c.302cGg>cTg_NP_001138387.1:p.101R>L Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4j23 1 P21802 99.55 2e-161 X-RAY
2014-02-19 ARG A:45 A:190 161.0 0.716 65.9 174.0 161.0 0.716 0.0
1ev2 2 P21802 100.0 3e-161 X-RAY
2000-05-31 ARG E:44 E:190 129.0 0.573 E -137.9 144.1 118.0 0.524 0.049 C:P09038:0.049
HOH
3.630
CA
O
ARG F:44 F:190 147.0 0.653 E -138.2 144.5 147.0 0.653 0.0 HOH
3.904
CA
O
ARG G:44 G:190 109.0 0.484 E -137.7 144.2 109.0 0.484 0.0 HOH
3.641
CA
O
ARG H:44 H:190 107.0 0.476 E -137.9 142.4 107.0 0.476 0.0 HOH
3.647
CA
O
1e0o 2 P21802 100.0 2e-160 X-RAY
2000-10-23 ARG B:43 B:190 122.0 0.542 E -143.4 156.9 122.0 0.542 0.0 HOH
8.854
O
O
ARG D:43 D:190 116.0 0.516 E -143.8 149.9 116.0 0.516 0.0 HOH
2.845
NH2
O
1iil 2 P21802 99.55 4e-160 X-RAY
2001-05-09 ARG E:44 E:190 122.0 0.542 E -133.7 146.1 122.0 0.542 0.0 HOH
8.710
O
O
ARG F:44 F:190 116.0 0.516 E -133.6 145.6 NA NA NA
ARG G:44 G:190 117.0 0.52 E -133.3 145.9 NA NA NA
ARG H:44 H:190 118.0 0.524 E -133.1 146.2 NA NA NA
2fdb 2 Q9UQH9 99.55 4e-160 X-RAY
2006-02-07 ARG B:42 P:2190 112.0 0.498 E -135.3 154.1 112.0 0.498 0.0 HOH
3.787
CA
O
ARG D:42 R:3190 131.0 0.582 E -136.0 154.4 NA NA NA
1ii4 2 P21802 99.55 6e-160 X-RAY
2001-05-09 ARG E:44 E:190 115.0 0.511 E -129.8 153.2 115.0 0.511 0.0
ARG F:44 F:190 117.0 0.52 E -128.6 152.9 NA NA NA
ARG G:44 G:190 122.0 0.542 E -127.5 154.5 NA NA NA
ARG H:44 H:190 122.0 0.542 E -128.4 155.3 NA NA NA
1djs 1 P21802 100.0 4e-153 X-RAY
2000-01-12 ARG A:44 A:190 117.0 0.52 E -145.1 144.2 117.0 0.52 0.0 HOH
2.827
NH1
O
1nun 2 P21802 88.36 1e-145 X-RAY
2003-02-11 ARG B:51 B:190 107.0 0.476 E -133.8 145.2 107.0 0.476 0.0
3oj2 2 P21802 87.93 1e-144 X-RAY
2011-08-31 ARG C:52 C:190 111.0 0.493 E -144.9 157.9 111.0 0.493 0.0 HOH
3.398
CA
O
ARG D:52 D:190 106.0 0.471 E -143.1 157.9 NA NA NA
3ojm 2 P21802 87.93 1e-144 X-RAY
2011-08-31 ARG B:52 B:190 114.0 0.507 E -141.9 147.8 114.0 0.507 0.0 HOH
3.743
C
O
3dar 1 P21802 100.0 7e-70 X-RAY
2008-06-10 ARG A:46 A:190 119.0 0.529 E -139.4 156.0 119.0 0.529 0.0 HOH
2.794
NH1
O
ARG B:46 B:190 140.0 0.622 E -139.7 155.5 NA NA NA
3caf 1 P21802 100.0 4e-67 X-RAY
2009-01-27 ARG A:41 A:190 121.0 0.538 E -143.0 156.7 121.0 0.538 0.0 HOH
3.662
CA
O
3cu1 1 P21802 100.0 4e-67 X-RAY
2009-04-21 ARG A:41 A:190 113.0 0.502 E -151.8 158.1 113.0 0.502 0.0 HOH
3.455
CA
O
ARG C:41 C:190 124.0 0.551 E -144.7 162.6 124.0 0.551 0.0 HOH
3.045
CA
O
3euu 1 P21802 100.0 4e-67 X-RAY
2009-08-25 ARG A:41 A:190 114.0 0.507 E -145.7 158.2 114.0 0.507 0.0 HOH
2.850
NH1
O
ARG B:41 B:190 111.0 0.493 E -140.4 163.4 NA NA NA
4wv1 1 P21802 100.0 2e-66 X-RAY
2015-09-16 ARG A:38 F:187 115.0 0.511 E -123.9 159.2 115.0 0.511 0.0
ARG B:38 C:187 113.0 0.502 E -124.5 158.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21802-f1 1 P21802 100.0 0.0 ARG A:190 A:190 99.0 0.44 E -134.7 162.4