Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 123310895 | . | C | A | CCDS53584.1:NM_001144915.1:c.266cGc>cTc_NP_001138387.1:p.89R>L | Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4j23 | 1 | P21802 | 99.55 | 2e-161 |
X-RAY |
2014-02-19 | ARG | A:33 | A:178 | 81.0 | 0.36 | E | -105.2 | 145.8 | 81.0 | 0.36 | 0.0 | ||||||
1ev2 | 2 | P21802 | 100.0 | 3e-161 |
X-RAY |
2000-05-31 | ARG | E:32 | E:178 | 93.0 | 0.413 | E | -130.4 | 148.8 | 93.0 | 0.413 | 0.0 |
HOH |
2.878 |
N |
O |
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ARG | F:32 | F:178 | 95.0 | 0.422 | E | -131.5 | 147.3 | 95.0 | 0.422 | 0.0 |
HOH |
3.173 |
N |
O |
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ARG | G:32 | G:178 | 81.0 | 0.36 | E | -129.9 | 148.5 | 81.0 | 0.36 | 0.0 |
HOH |
3.309 |
NH1 |
O |
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ARG | H:32 | H:178 | 103.0 | 0.458 | E | -131.5 | 147.9 | 103.0 | 0.458 | 0.0 |
HOH |
9.562 |
O |
O |
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1e0o | 2 | P21802 | 100.0 | 2e-160 |
X-RAY |
2000-10-23 | ARG | B:31 | B:178 | 49.0 | 0.218 | E | -130.5 | 145.1 | 49.0 | 0.218 | 0.0 |
IDS SGN IDS HOH |
6.867 3.302 6.047 3.369 |
NH2 CD NH1 NH2 |
O2S O2S O6A O |
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ARG | D:31 | D:178 | 82.0 | 0.364 | E | -124.6 | 139.6 | 82.0 | 0.364 | 0.0 |
SO4 SO4 HOH |
3.470 3.390 2.782 |
NH2 NH1 N |
O3 O2 O |
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1iil | 2 | P21802 | 99.55 | 4e-160 |
X-RAY |
2001-05-09 | ARG | E:32 | E:178 | 84.0 | 0.373 | E | -129.7 | 143.6 | 84.0 | 0.373 | 0.0 | ||||||
ARG | F:32 | F:178 | 79.0 | 0.351 | E | -129.8 | 143.4 | NA | NA | NA | |||||||||||||
ARG | G:32 | G:178 | 49.0 | 0.218 | E | -130.1 | 144.3 | NA | NA | NA | |||||||||||||
ARG | H:32 | H:178 | 47.0 | 0.209 | E | -130.1 | 144.2 | NA | NA | NA | |||||||||||||
2fdb | 2 | Q9UQH9 | 99.55 | 4e-160 |
X-RAY |
2006-02-07 | ARG | B:30 | P:2178 | 86.0 | 0.382 | E | -127.2 | 144.0 | 86.0 | 0.382 | 0.0 |
HOH |
9.688 |
O |
O |
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ARG | D:30 | R:3178 | 21.0 | NA | E | -127.5 | 145.1 | NA | NA | NA | |||||||||||||
1ii4 | 2 | P21802 | 99.55 | 6e-160 |
X-RAY |
2001-05-09 | ARG | E:32 | E:178 | 85.0 | 0.378 | E | -122.1 | 146.4 | 85.0 | 0.378 | 0.0 | ||||||
ARG | F:32 | F:178 | 87.0 | 0.387 | E | -121.3 | 145.3 | NA | NA | NA | |||||||||||||
ARG | G:32 | G:178 | 89.0 | 0.396 | E | -120.5 | 146.7 | NA | NA | NA | |||||||||||||
ARG | H:32 | H:178 | 89.0 | 0.396 | E | -121.3 | 145.7 | NA | NA | NA | |||||||||||||
1djs | 1 | P21802 | 100.0 | 4e-153 |
X-RAY |
2000-01-12 | ARG | A:32 | A:178 | 81.0 | 0.36 | E | -114.5 | 148.0 | 60.0 | 0.267 | 0.093 |
A:P21802:0.093 |
SO4 SO4 SO4 HOH |
5.253 5.757 2.423 2.720 |
NH1 NH1 NH2 N |
O4 O3 O2 O |
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1nun | 2 | P21802 | 88.36 | 1e-145 |
X-RAY |
2003-02-11 | ARG | B:39 | B:178 | 73.0 | 0.324 | E | -138.4 | 154.4 | 73.0 | 0.324 | 0.0 | ||||||
3oj2 | 2 | P21802 | 87.93 | 1e-144 |
X-RAY |
2011-08-31 | ARG | C:40 | C:178 | 91.0 | 0.404 | E | -132.5 | 154.0 | 91.0 | 0.404 | 0.0 |
HOH |
6.491 |
NH2 |
O |
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ARG | D:40 | D:178 | 112.0 | 0.498 | E | -131.8 | 153.0 | NA | NA | NA | |||||||||||||
3ojm | 2 | P21802 | 87.93 | 1e-144 |
X-RAY |
2011-08-31 | ARG | B:40 | B:178 | 62.0 | 0.276 | E | -140.6 | 149.1 | 62.0 | 0.276 | 0.0 |
HOH |
5.837 |
O |
O |
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3dar | 1 | P21802 | 100.0 | 7e-70 |
X-RAY |
2008-06-10 | ARG | A:34 | A:178 | 43.0 | NA | E | -131.7 | 147.1 | 43.0 | NA | NA |
HOH |
3.072 |
N |
O |
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ARG | B:34 | B:178 | 54.0 | NA | E | -133.1 | 147.7 | NA | NA | NA | |||||||||||||
3caf | 1 | P21802 | 100.0 | 4e-67 |
X-RAY |
2009-01-27 | ARG | A:29 | A:178 | 94.0 | 0.418 | E | -130.4 | 150.0 | 94.0 | 0.418 | 0.0 |
HOH |
3.070 |
N |
O |
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3cu1 | 1 | P21802 | 100.0 | 4e-67 |
X-RAY |
2009-04-21 | ARG | A:29 | A:178 | 79.0 | 0.351 | E | -129.5 | 150.4 | 79.0 | 0.351 | 0.0 |
HOH |
3.033 |
N |
O |
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ARG | C:29 | C:178 | 72.0 | 0.32 | E | -129.7 | 153.9 | 46.0 | 0.204 | 0.116 |
A:P21802:0.116 |
GU4 YYJ HOH |
3.339 3.213 2.718 |
NH1 NH1 N |
O28 O1S3 O |
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3euu | 1 | P21802 | 100.0 | 4e-67 |
X-RAY |
2009-08-25 | ARG | A:29 | A:178 | 78.0 | 0.347 | E | -138.9 | 141.1 | 78.0 | 0.347 | 0.0 |
HOH |
3.079 |
N |
O |
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ARG | B:29 | B:178 | 79.0 | 0.351 | E | -127.0 | 147.8 | NA | NA | NA | |||||||||||||
4wv1 | 1 | P21802 | 100.0 | 2e-66 |
X-RAY |
2015-09-16 | ARG | A:26 | F:175 | 137.0 | 0.609 | E | -115.3 | 149.1 | 20.0 | 0.089 | 0.52 |
F:None:0.187 D:None:0.378 |
HOH |
3.624 |
NH2 |
O |
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ARG | B:26 | C:175 | 133.0 | 0.591 | E | -115.4 | 148.8 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p21802-f1 | 1 | P21802 | 100.0 | 0.0 | ARG | A:178 | A:178 | 107.0 | 0.476 | E | -136.7 | 136.0 |