Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 126086524 | . | A | C | CCDS7639.1:NM_000274.3:c.1307aTc>aGc_NP_000265.1:p.436I>S | Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-04-01 | ILE | A:436 | A:436 | 2.0 | 0.011 | H | -57.9 | -45.4 | 2.0 | 0.011 | 0.0 |
HOH |
8.641 |
N |
O |
||
| ILE | B:436 | B:436 | 2.0 | 0.011 | H | -57.2 | -41.7 | 2.0 | 0.011 | 0.0 |
HOH |
6.878 |
O |
O |
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| ILE | C:436 | C:436 | 2.0 | 0.011 | H | -59.3 | -42.4 | NA | NA | NA | |||||||||||||
| 2oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-12-09 | ILE | A:436 | A:436 | 3.0 | 0.017 | H | -58.4 | -46.0 | NA | NA | NA | ||||||
| ILE | B:436 | B:436 | 4.0 | 0.023 | H | -57.1 | -48.1 | NA | NA | NA | |||||||||||||
| ILE | C:436 | C:436 | 2.0 | 0.011 | H | -58.6 | -50.0 | 2.0 | 0.011 | 0.0 |
HOH |
6.126 |
N |
O |
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| 2byj | 1 | P04181 | 99.77 | 0.0 |
X-RAY |
2005-09-07 | ILE | A:436 | A:436 | 3.0 | 0.017 | H | -58.7 | -47.9 | 3.0 | 0.017 | 0.0 | ||||||
| ILE | B:436 | B:436 | 3.0 | 0.017 | H | -58.8 | -47.7 | 3.0 | 0.017 | 0.0 | |||||||||||||
| ILE | C:436 | C:436 | 3.0 | 0.017 | H | -58.4 | -48.1 | NA | NA | NA | |||||||||||||
| 2byl | 1 | P04181 | 99.32 | 0.0 |
X-RAY |
2005-09-07 | ILE | A:436 | A:436 | 4.0 | 0.023 | H | -53.5 | -48.0 | 4.0 | 0.023 | 0.0 | ||||||
| ILE | B:436 | B:436 | 4.0 | 0.023 | H | -59.9 | -47.3 | 4.0 | 0.023 | 0.0 |
HOH |
5.937 |
C |
O |
|||||||||
| ILE | C:436 | C:436 | 7.0 | 0.04 | H | -56.9 | -40.7 | NA | NA | NA | |||||||||||||
| 6hx7 | 1 | P04181 | 99.76 | 0.0 |
X-RAY |
2019-06-05 | ILE | A:412 | A:436 | 12.0 | 0.069 | H | -61.8 | -43.7 | 12.0 | 0.069 | 0.0 |
HOH |
2.899 |
O |
O |
||
| ILE | B:412 | B:436 | 11.0 | 0.063 | H | -62.1 | -43.7 | NA | NA | NA | |||||||||||||
| ILE | C:412 | C:436 | 2.0 | 0.011 | H | -60.5 | -42.8 | NA | NA | NA | |||||||||||||
| 5vwo | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2017-08-30 | ILE | A:401 | A:436 | 3.0 | 0.017 | H | -61.9 | -45.1 | 3.0 | 0.017 | 0.0 |
HOH |
3.089 |
O |
O |
||
| ILE | B:401 | B:436 | 4.0 | 0.023 | H | -61.3 | -46.5 | 4.0 | 0.023 | 0.0 |
HOH |
2.560 |
O |
O |
|||||||||
| ILE | C:401 | C:436 | 6.0 | 0.034 | H | -62.6 | -45.5 | 6.0 | 0.034 | 0.0 |
HOH |
6.508 |
N |
O |
|||||||||
| 6oia | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | ILE | A:401 | A:436 | 2.0 | 0.011 | H | -62.7 | -58.2 | 2.0 | 0.011 | 0.0 |
HOH |
6.514 |
N |
O |
||
| ILE | B:401 | B:436 | 2.0 | 0.011 | H | -61.3 | -45.6 | 2.0 | 0.011 | 0.0 |
HOH |
2.329 |
O |
O |
|||||||||
| ILE | C:401 | C:436 | 5.0 | 0.029 | H | -62.5 | -45.5 | NA | NA | NA | |||||||||||||
| 6v8c | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | ILE | A:401 | A:436 | 2.0 | 0.011 | H | -60.4 | -44.1 | 2.0 | 0.011 | 0.0 |
HOH |
6.365 |
N |
O |
||
| ILE | B:401 | B:436 | 2.0 | 0.011 | H | -58.9 | -43.5 | NA | NA | NA | |||||||||||||
| ILE | C:401 | C:436 | 4.0 | 0.023 | H | -59.6 | -45.8 | NA | NA | NA | |||||||||||||
| 6v8d | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | ILE | A:401 | A:436 | 5.0 | 0.029 | H | -61.1 | -43.3 | 5.0 | 0.029 | 0.0 |
HOH |
8.232 |
O |
O |
||
| ILE | B:401 | B:436 | 1.0 | 0.006 | H | -60.1 | -44.0 | 1.0 | 0.006 | 0.0 |
HOH |
8.057 |
O |
O |
|||||||||
| ILE | C:401 | C:436 | 6.0 | 0.034 | H | -59.8 | -49.9 | NA | NA | NA | |||||||||||||
| 7jx9 | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-01-06 | ILE | A:401 | A:436 | 4.0 | 0.023 | H | -61.3 | -41.1 | 4.0 | 0.023 | 0.0 |
HOH |
6.487 |
C |
O |
||
| ILE | B:401 | B:436 | 6.0 | 0.034 | H | -60.7 | -53.6 | NA | NA | NA | |||||||||||||
| ILE | C:401 | C:436 | 3.0 | 0.017 | H | -66.9 | -38.9 | NA | NA | NA | |||||||||||||
| 7lnm | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | ILE | A:401 | B:436 | 4.0 | 0.023 | H | -61.0 | -46.6 | 4.0 | 0.023 | 0.0 |
HOH |
2.514 |
O |
O |
||
| ILE | B:401 | C:436 | 2.0 | 0.011 | H | -62.0 | -55.8 | 2.0 | 0.011 | 0.0 | |||||||||||||
| ILE | C:401 | E:436 | 2.0 | 0.011 | H | -64.2 | -47.2 | NA | NA | NA | |||||||||||||
| ILE | D:401 | F:436 | 1.0 | 0.006 | H | -62.2 | -53.1 | NA | NA | NA | |||||||||||||
| ILE | E:401 | I:436 | 5.0 | 0.029 | H | -62.9 | -43.6 | NA | NA | NA | |||||||||||||
| ILE | F:401 | J:436 | 5.0 | 0.029 | H | -61.6 | -42.6 | NA | NA | NA | |||||||||||||
| 7lom | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | ILE | A:401 | A:436 | 5.0 | 0.029 | H | -72.4 | -35.6 | 5.0 | 0.029 | 0.0 |
HOH |
2.935 |
O |
O |
||
| ILE | B:401 | B:436 | 4.0 | 0.023 | H | -66.0 | -45.8 | NA | NA | NA | |||||||||||||
| ILE | C:401 | C:436 | 6.0 | 0.034 | H | -67.2 | -44.0 | NA | NA | NA | |||||||||||||
| 7lon | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | ILE | A:401 | B:436 | 4.0 | 0.023 | H | -63.3 | -41.6 | 4.0 | 0.023 | 0.0 |
HOH |
6.489 |
C |
O |
||
| ILE | B:401 | A:436 | 3.0 | 0.017 | H | -64.2 | -42.9 | NA | NA | NA | |||||||||||||
| ILE | C:401 | C:436 | 5.0 | 0.029 | H | -64.9 | -43.6 | NA | NA | NA | |||||||||||||
| 1gbn | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | ILE | A:399 | A:436 | 2.0 | 0.011 | H | -59.7 | -40.1 | 2.0 | 0.011 | 0.0 |
HOH |
6.261 |
N |
O |
||
| ILE | B:399 | B:436 | 2.0 | 0.011 | H | -60.5 | -40.4 | 2.0 | 0.011 | 0.0 |
HOH |
7.859 |
CG2 |
O |
|||||||||
| ILE | C:399 | C:436 | 2.0 | 0.011 | H | -60.3 | -40.4 | 2.0 | 0.011 | 0.0 | |||||||||||||
| 2can | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | ILE | A:399 | A:436 | 2.0 | 0.011 | H | -55.7 | -49.7 | 2.0 | 0.011 | 0.0 |
HOH |
6.216 |
N |
O |
||
| ILE | B:399 | B:436 | 1.0 | 0.006 | H | -56.5 | -49.4 | 1.0 | 0.006 | 0.0 | |||||||||||||
| ILE | C:399 | C:436 | 2.0 | 0.011 | H | -56.9 | -49.2 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04181-f1 | 1 | P04181 | 100.0 | 0.0 | ILE | A:436 | A:436 | 1.0 | 0.006 | H | -63.0 | -46.9 | |