Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 126086576 | . | C | A | CCDS7639.1:NM_000274.3:c.1255Gtg>Ttg_NP_000265.1:p.419V>L | Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-04-01 | VAL | A:419 | A:419 | 33.0 | 0.213 | T | -78.0 | -5.2 | 33.0 | 0.213 | 0.0 |
HOH |
4.573 |
CG2 |
O |
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| VAL | B:419 | B:419 | 33.0 | 0.213 | T | -77.8 | -10.5 | 33.0 | 0.213 | 0.0 |
HOH |
4.590 |
CG2 |
O |
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| VAL | C:419 | C:419 | 32.0 | 0.206 | T | -81.6 | -6.7 | NA | NA | NA | |||||||||||||
| 2oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-12-09 | VAL | A:419 | A:419 | 38.0 | 0.245 | T | -85.2 | -6.9 | NA | NA | NA | ||||||
| VAL | B:419 | B:419 | 36.0 | 0.232 | T | -85.1 | -3.0 | NA | NA | NA | |||||||||||||
| VAL | C:419 | C:419 | 36.0 | 0.232 | T | -88.3 | -3.4 | 36.0 | 0.232 | 0.0 |
HOH |
2.834 |
O |
O |
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| 2byj | 1 | P04181 | 99.77 | 0.0 |
X-RAY |
2005-09-07 | VAL | A:419 | A:419 | 39.0 | 0.252 | T | -77.1 | -8.0 | 39.0 | 0.252 | 0.0 | ||||||
| VAL | B:419 | B:419 | 38.0 | 0.245 | T | -77.0 | -8.4 | 38.0 | 0.245 | 0.0 | |||||||||||||
| VAL | C:419 | C:419 | 36.0 | 0.232 | T | -77.4 | -8.8 | NA | NA | NA | |||||||||||||
| 2byl | 1 | P04181 | 99.32 | 0.0 |
X-RAY |
2005-09-07 | VAL | A:419 | A:419 | 37.0 | 0.239 | T | -80.1 | -2.8 | 37.0 | 0.239 | 0.0 |
HOH |
3.993 |
CG2 |
O |
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| VAL | B:419 | B:419 | 38.0 | 0.245 | T | -82.3 | -1.5 | 38.0 | 0.245 | 0.0 |
HOH |
2.686 |
O |
O |
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| VAL | C:419 | C:419 | 34.0 | 0.219 | T | -82.7 | -10.9 | NA | NA | NA | |||||||||||||
| 6hx7 | 1 | P04181 | 99.76 | 0.0 |
X-RAY |
2019-06-05 | VAL | A:395 | A:419 | 35.0 | 0.226 | T | -85.1 | 1.8 | 35.0 | 0.226 | 0.0 |
HOH |
2.664 |
O |
O |
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| VAL | B:395 | B:419 | 35.0 | 0.226 | T | -84.5 | 3.8 | NA | NA | NA | |||||||||||||
| VAL | C:395 | C:419 | 28.0 | 0.181 | T | -84.9 | 2.0 | NA | NA | NA | |||||||||||||
| 5vwo | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2017-08-30 | VAL | A:384 | A:419 | 31.0 | 0.2 | T | -87.9 | 4.4 | 31.0 | 0.2 | 0.0 |
HOH |
2.636 |
O |
O |
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| VAL | B:384 | B:419 | 34.0 | 0.219 | T | -79.4 | -2.7 | 34.0 | 0.219 | 0.0 |
HOH |
2.775 |
O |
O |
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| VAL | C:384 | C:419 | 28.0 | 0.181 | T | -88.3 | 0.2 | 28.0 | 0.181 | 0.0 |
HOH |
2.915 |
O |
O |
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| 6oia | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | VAL | A:384 | A:419 | 36.0 | 0.232 | T | -79.9 | 0.6 | 36.0 | 0.232 | 0.0 |
HOH |
2.893 |
O |
O |
||
| VAL | B:384 | B:419 | 33.0 | 0.213 | T | -83.7 | -1.2 | 33.0 | 0.213 | 0.0 |
HOH |
2.831 |
O |
O |
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| VAL | C:384 | C:419 | 27.0 | 0.174 | T | -78.6 | -1.0 | NA | NA | NA | |||||||||||||
| 6v8c | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | VAL | A:384 | A:419 | 34.0 | 0.219 | T | -83.1 | -2.9 | 34.0 | 0.219 | 0.0 |
HOH |
2.570 |
O |
O |
||
| VAL | B:384 | B:419 | 34.0 | 0.219 | T | -82.9 | -0.6 | NA | NA | NA | |||||||||||||
| VAL | C:384 | C:419 | 36.0 | 0.232 | T | -84.0 | -1.0 | NA | NA | NA | |||||||||||||
| 6v8d | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | VAL | A:384 | A:419 | 29.0 | 0.187 | T | -86.1 | 8.4 | 29.0 | 0.187 | 0.0 |
HOH |
2.645 |
O |
O |
||
| VAL | B:384 | B:419 | 23.0 | 0.148 | T | -84.2 | 3.9 | 23.0 | 0.148 | 0.0 |
HOH |
2.796 |
O |
O |
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| VAL | C:384 | C:419 | 31.0 | 0.2 | T | -79.1 | 0.4 | NA | NA | NA | |||||||||||||
| 7jx9 | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-01-06 | VAL | A:384 | A:419 | 32.0 | 0.206 | T | -92.4 | 4.6 | 32.0 | 0.206 | 0.0 |
HOH |
5.102 |
CG2 |
O |
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| VAL | B:384 | B:419 | 37.0 | 0.239 | T | -89.4 | 7.0 | NA | NA | NA | |||||||||||||
| VAL | C:384 | C:419 | 36.0 | 0.232 | T | -86.8 | 3.4 | NA | NA | NA | |||||||||||||
| 7lnm | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | VAL | A:384 | B:419 | 31.0 | 0.2 | T | -82.2 | 1.7 | 31.0 | 0.2 | 0.0 |
HOH |
2.808 |
O |
O |
||
| VAL | B:384 | C:419 | 33.0 | 0.213 | T | -87.5 | 3.6 | 33.0 | 0.213 | 0.0 |
HOH |
2.953 |
O |
O |
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| VAL | C:384 | E:419 | 32.0 | 0.206 | T | -83.4 | 0.6 | NA | NA | NA | |||||||||||||
| VAL | D:384 | F:419 | 31.0 | 0.2 | T | -84.3 | 2.0 | NA | NA | NA | |||||||||||||
| VAL | E:384 | I:419 | 35.0 | 0.226 | T | -82.1 | 0.3 | NA | NA | NA | |||||||||||||
| VAL | F:384 | J:419 | 36.0 | 0.232 | T | -81.8 | 1.0 | NA | NA | NA | |||||||||||||
| 7lom | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | VAL | A:384 | A:419 | 30.0 | 0.194 | T | -86.2 | 0.0 | 30.0 | 0.194 | 0.0 |
HOH |
3.683 |
CG2 |
O |
||
| VAL | B:384 | B:419 | 36.0 | 0.232 | T | -88.9 | 3.4 | NA | NA | NA | |||||||||||||
| VAL | C:384 | C:419 | 33.0 | 0.213 | T | -82.8 | 4.2 | NA | NA | NA | |||||||||||||
| 7lon | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | VAL | A:384 | B:419 | 33.0 | 0.213 | T | -77.3 | 4.1 | 33.0 | 0.213 | 0.0 |
HOH |
2.888 |
O |
O |
||
| VAL | B:384 | A:419 | 33.0 | 0.213 | T | -78.8 | 4.3 | NA | NA | NA | |||||||||||||
| VAL | C:384 | C:419 | 34.0 | 0.219 | T | -78.6 | 3.7 | NA | NA | NA | |||||||||||||
| 1gbn | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | VAL | A:382 | A:419 | 29.0 | 0.187 | T | -86.2 | 3.3 | 29.0 | 0.187 | 0.0 |
HOH |
4.252 |
CG2 |
O |
||
| VAL | B:382 | B:419 | 30.0 | 0.194 | T | -85.0 | 2.4 | 30.0 | 0.194 | 0.0 |
HOH |
4.526 |
CG2 |
O |
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| VAL | C:382 | C:419 | 28.0 | 0.181 | T | -87.0 | 3.4 | 28.0 | 0.181 | 0.0 |
HOH |
7.961 |
CG1 |
O |
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| 2can | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | VAL | A:382 | A:419 | 29.0 | 0.187 | T | -92.9 | 0.3 | 29.0 | 0.187 | 0.0 |
HOH |
4.314 |
CG2 |
O |
||
| VAL | B:382 | B:419 | 32.0 | 0.206 | T | -92.3 | -0.8 | 32.0 | 0.206 | 0.0 |
HOH |
8.137 |
CG1 |
O |
|||||||||
| VAL | C:382 | C:419 | 30.0 | 0.194 | T | -93.3 | -0.0 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04181-f1 | 1 | P04181 | 100.0 | 0.0 | VAL | A:419 | A:419 | 32.0 | 0.206 | T | -75.6 | -1.5 | |