Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 126086659 | . | C | A | CCDS7639.1:NM_000274.3:c.1172tGg>tTg_NP_000265.1:p.391W>L | Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-04-01 | TRP | A:391 | A:391 | 66.0 | 0.259 | H | -68.6 | -39.8 | 66.0 | 0.259 | 0.0 |
HOH |
7.049 |
CZ3 |
O |
||
| TRP | B:391 | B:391 | 66.0 | 0.259 | H | -70.7 | -39.5 | 66.0 | 0.259 | 0.0 |
HOH |
4.286 |
CE3 |
O |
|||||||||
| TRP | C:391 | C:391 | 66.0 | 0.259 | H | -66.4 | -43.0 | NA | NA | NA | |||||||||||||
| 2oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-12-09 | TRP | A:391 | A:391 | 68.0 | 0.267 | H | -63.5 | -43.5 | NA | NA | NA | ||||||
| TRP | B:391 | B:391 | 72.0 | 0.282 | H | -61.2 | -45.6 | NA | NA | NA | |||||||||||||
| TRP | C:391 | C:391 | 70.0 | 0.275 | H | -59.1 | -49.1 | 70.0 | 0.275 | 0.0 |
HOH |
2.750 |
NE1 |
O |
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| 2byj | 1 | P04181 | 99.77 | 0.0 |
X-RAY |
2005-09-07 | TRP | A:391 | A:391 | 68.0 | 0.267 | H | -63.0 | -48.8 | 68.0 | 0.267 | 0.0 |
HOH |
3.497 |
CZ3 |
O |
||
| TRP | B:391 | B:391 | 65.0 | 0.255 | H | -63.1 | -48.4 | 65.0 | 0.255 | 0.0 |
HOH |
9.266 |
N |
O |
|||||||||
| TRP | C:391 | C:391 | 67.0 | 0.263 | H | -63.4 | -48.6 | NA | NA | NA | |||||||||||||
| 2byl | 1 | P04181 | 99.32 | 0.0 |
X-RAY |
2005-09-07 | TRP | A:391 | A:391 | 66.0 | 0.259 | H | -63.0 | -46.7 | 66.0 | 0.259 | 0.0 |
HOH |
3.984 |
CZ3 |
O |
||
| TRP | B:391 | B:391 | 63.0 | 0.247 | H | -60.9 | -46.3 | 63.0 | 0.247 | 0.0 |
HOH |
2.984 |
NE1 |
O |
|||||||||
| TRP | C:391 | C:391 | 63.0 | 0.247 | H | -67.1 | -50.0 | NA | NA | NA | |||||||||||||
| 6hx7 | 1 | P04181 | 99.76 | 0.0 |
X-RAY |
2019-06-05 | TRP | A:367 | A:391 | 70.0 | 0.275 | H | -59.1 | -48.3 | 70.0 | 0.275 | 0.0 |
HOH |
3.367 |
NE1 |
O |
||
| TRP | B:367 | B:391 | 71.0 | 0.278 | H | -60.3 | -47.6 | NA | NA | NA | |||||||||||||
| TRP | C:367 | C:391 | 72.0 | 0.282 | H | -61.4 | -47.8 | NA | NA | NA | |||||||||||||
| 5vwo | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2017-08-30 | TRP | A:356 | A:391 | 55.0 | 0.216 | H | -59.8 | -48.1 | 55.0 | 0.216 | 0.0 |
HOH |
3.168 |
N |
O |
||
| TRP | B:356 | B:391 | 56.0 | 0.22 | H | -64.4 | -43.2 | 56.0 | 0.22 | 0.0 |
HOH |
2.721 |
NE1 |
O |
|||||||||
| TRP | C:356 | C:391 | 61.0 | 0.239 | H | -65.3 | -47.7 | 61.0 | 0.239 | 0.0 |
HOH |
2.906 |
N |
O |
|||||||||
| 6oia | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | TRP | A:356 | A:391 | 82.0 | 0.322 | H | -61.4 | -35.6 | 82.0 | 0.322 | 0.0 |
HOH |
3.731 |
CG |
O |
||
| TRP | B:356 | B:391 | 68.0 | 0.267 | H | -61.3 | -44.3 | 68.0 | 0.267 | 0.0 |
HOH |
2.706 |
NE1 |
O |
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| TRP | C:356 | C:391 | 83.0 | 0.325 | H | -62.5 | -46.3 | NA | NA | NA | |||||||||||||
| 6v8c | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | TRP | A:356 | A:391 | 76.0 | 0.298 | H | -64.7 | -42.5 | 76.0 | 0.298 | 0.0 |
HOH |
3.107 |
N |
O |
||
| TRP | B:356 | B:391 | 74.0 | 0.29 | H | -62.1 | -45.1 | NA | NA | NA | |||||||||||||
| TRP | C:356 | C:391 | 71.0 | 0.278 | H | -63.1 | -45.6 | NA | NA | NA | |||||||||||||
| 6v8d | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | TRP | A:356 | A:391 | 51.0 | 0.2 | H | -65.8 | -43.3 | 51.0 | 0.2 | 0.0 |
HOH |
3.325 |
N |
O |
||
| TRP | B:356 | B:391 | 67.0 | 0.263 | H | -65.2 | -40.8 | 67.0 | 0.263 | 0.0 |
HOH |
2.925 |
N |
O |
|||||||||
| TRP | C:356 | C:391 | 68.0 | 0.267 | H | -60.2 | -44.4 | NA | NA | NA | |||||||||||||
| 7jx9 | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-01-06 | TRP | A:356 | A:391 | 56.0 | 0.22 | H | -66.2 | -49.4 | 56.0 | 0.22 | 0.0 |
HOH |
3.077 |
NE1 |
O |
||
| TRP | B:356 | B:391 | 67.0 | 0.263 | H | -64.3 | -44.8 | NA | NA | NA | |||||||||||||
| TRP | C:356 | C:391 | 64.0 | 0.251 | H | -63.7 | -46.5 | NA | NA | NA | |||||||||||||
| 7lnm | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TRP | A:356 | B:391 | 68.0 | 0.267 | H | -64.3 | -43.8 | 68.0 | 0.267 | 0.0 |
HOH |
2.919 |
NE1 |
O |
||
| TRP | B:356 | C:391 | 72.0 | 0.282 | H | -63.8 | -42.3 | 72.0 | 0.282 | 0.0 |
HOH |
6.970 |
CZ3 |
O |
|||||||||
| TRP | C:356 | E:391 | 70.0 | 0.275 | H | -62.9 | -44.3 | NA | NA | NA | |||||||||||||
| TRP | D:356 | F:391 | 58.0 | 0.227 | H | -65.8 | -42.1 | NA | NA | NA | |||||||||||||
| TRP | E:356 | I:391 | 77.0 | 0.302 | H | -65.4 | -44.4 | NA | NA | NA | |||||||||||||
| TRP | F:356 | J:391 | 72.0 | 0.282 | H | -62.9 | -43.9 | NA | NA | NA | |||||||||||||
| 7lom | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TRP | A:356 | A:391 | 67.0 | 0.263 | H | -66.5 | -42.6 | 67.0 | 0.263 | 0.0 |
HOH |
6.667 |
CZ3 |
O |
||
| TRP | B:356 | B:391 | 69.0 | 0.271 | H | -67.0 | -41.4 | NA | NA | NA | |||||||||||||
| TRP | C:356 | C:391 | 66.0 | 0.259 | H | -66.2 | -43.9 | NA | NA | NA | |||||||||||||
| 7lon | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TRP | A:356 | B:391 | 70.0 | 0.275 | H | -60.2 | -48.6 | 70.0 | 0.275 | 0.0 |
HOH |
3.522 |
CE2 |
O |
||
| TRP | B:356 | A:391 | 68.0 | 0.267 | H | -60.4 | -47.6 | NA | NA | NA | |||||||||||||
| TRP | C:356 | C:391 | 67.0 | 0.263 | H | -61.9 | -49.8 | NA | NA | NA | |||||||||||||
| 1gbn | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | TRP | A:354 | A:391 | 64.0 | 0.251 | H | -63.8 | -47.0 | 64.0 | 0.251 | 0.0 |
HOH |
6.721 |
O |
O |
||
| TRP | B:354 | B:391 | 65.0 | 0.255 | H | -63.9 | -47.3 | 65.0 | 0.255 | 0.0 |
HOH |
5.546 |
CZ2 |
O |
|||||||||
| TRP | C:354 | C:391 | 65.0 | 0.255 | H | -64.6 | -47.2 | 65.0 | 0.255 | 0.0 |
HOH |
6.512 |
CH2 |
O |
|||||||||
| 2can | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | TRP | A:354 | A:391 | 69.0 | 0.271 | H | -60.5 | -47.5 | 69.0 | 0.271 | 0.0 |
HOH |
5.585 |
CZ2 |
O |
||
| TRP | B:354 | B:391 | 67.0 | 0.263 | H | -60.7 | -47.4 | 67.0 | 0.263 | 0.0 |
HOH |
5.904 |
CH2 |
O |
|||||||||
| TRP | C:354 | C:391 | 69.0 | 0.271 | H | -60.7 | -47.8 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04181-f1 | 1 | P04181 | 100.0 | 0.0 | TRP | A:391 | A:391 | 71.0 | 0.278 | H | -67.5 | -44.6 | |