Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 126086667 | . | C | A | CCDS7639.1:NM_000274.3:c.1164tgG>tgT_NP_000265.1:p.388W>C | Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-04-01 | TRP | A:388 | A:388 | 21.0 | 0.082 | B | -148.5 | 166.9 | 21.0 | 0.082 | 0.0 |
HOH |
7.898 |
NE1 |
O |
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| TRP | B:388 | B:388 | 15.0 | 0.059 | B | -159.8 | 156.8 | 15.0 | 0.059 | 0.0 |
HOH |
2.771 |
NE1 |
O |
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| TRP | C:388 | C:388 | 19.0 | 0.075 | B | -158.8 | 160.5 | NA | NA | NA | |||||||||||||
| 2oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-12-09 | TRP | A:388 | A:388 | 28.0 | 0.11 | -130.2 | 122.1 | NA | NA | NA | |||||||
| TRP | B:388 | B:388 | 21.0 | 0.082 | -133.3 | 126.2 | NA | NA | NA | ||||||||||||||
| TRP | C:388 | C:388 | 29.0 | 0.114 | -133.7 | 121.9 | 29.0 | 0.114 | 0.0 |
HOH |
6.840 |
C |
O |
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| 2byj | 1 | P04181 | 99.77 | 0.0 |
X-RAY |
2005-09-07 | TRP | A:388 | A:388 | 34.0 | 0.133 | -133.6 | 115.3 | 34.0 | 0.133 | 0.0 | |||||||
| TRP | B:388 | B:388 | 33.0 | 0.129 | -133.3 | 115.6 | 33.0 | 0.129 | 0.0 |
HOH |
4.754 |
N |
O |
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| TRP | C:388 | C:388 | 33.0 | 0.129 | -133.7 | 115.8 | NA | NA | NA | ||||||||||||||
| 2byl | 1 | P04181 | 99.32 | 0.0 |
X-RAY |
2005-09-07 | TRP | A:388 | A:388 | 33.0 | 0.129 | -138.1 | 124.6 | 33.0 | 0.129 | 0.0 | |||||||
| TRP | B:388 | B:388 | 30.0 | 0.118 | -141.6 | 122.8 | 30.0 | 0.118 | 0.0 |
HOH |
6.752 |
C |
O |
||||||||||
| TRP | C:388 | C:388 | 32.0 | 0.125 | B | -144.6 | 119.9 | NA | NA | NA | |||||||||||||
| 6hx7 | 1 | P04181 | 99.76 | 0.0 |
X-RAY |
2019-06-05 | TRP | A:364 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| TRP | B:364 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| TRP | C:364 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5vwo | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2017-08-30 | TRP | A:353 | A:388 | 22.0 | 0.086 | -122.8 | 118.7 | 22.0 | 0.086 | 0.0 |
HOH |
3.161 |
CB |
O |
|||
| TRP | B:353 | B:388 | 23.0 | 0.09 | S | -133.2 | 131.1 | 23.0 | 0.09 | 0.0 |
HOH |
5.456 |
CB |
O |
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| TRP | C:353 | C:388 | 22.0 | 0.086 | -123.4 | 130.3 | 22.0 | 0.086 | 0.0 |
HOH |
3.620 |
CD1 |
O |
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| 6oia | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | TRP | A:353 | A:388 | 31.0 | 0.122 | -144.4 | 121.1 | 31.0 | 0.122 | 0.0 |
HOH |
6.839 |
C |
O |
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| TRP | B:353 | B:388 | 28.0 | 0.11 | -140.7 | 123.6 | 28.0 | 0.11 | 0.0 |
HOH |
4.365 |
O |
O |
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| TRP | C:353 | C:388 | 34.0 | 0.133 | -143.9 | 123.4 | NA | NA | NA | ||||||||||||||
| 6v8c | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | TRP | A:353 | A:388 | 20.0 | 0.078 | -78.5 | 128.8 | 20.0 | 0.078 | 0.0 |
HOH |
5.011 |
O |
O |
|||
| TRP | B:353 | B:388 | 22.0 | 0.086 | -83.4 | 129.9 | NA | NA | NA | ||||||||||||||
| TRP | C:353 | C:388 | 27.0 | 0.106 | -91.0 | 133.0 | NA | NA | NA | ||||||||||||||
| 6v8d | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | TRP | A:353 | A:388 | 16.0 | 0.063 | -169.6 | 162.8 | 16.0 | 0.063 | 0.0 |
HOH |
5.359 |
CB |
O |
|||
| TRP | B:353 | B:388 | 18.0 | 0.071 | -161.4 | 164.4 | 18.0 | 0.071 | 0.0 |
HOH |
4.875 |
N |
O |
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| TRP | C:353 | C:388 | 16.0 | 0.063 | -170.8 | 175.0 | NA | NA | NA | ||||||||||||||
| 7jx9 | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-01-06 | TRP | A:353 | A:388 | 17.0 | 0.067 | -167.2 | 164.4 | 17.0 | 0.067 | 0.0 | |||||||
| TRP | B:353 | B:388 | 13.0 | 0.051 | -177.6 | 142.3 | NA | NA | NA | ||||||||||||||
| TRP | C:353 | C:388 | 18.0 | 0.071 | -175.6 | 145.3 | NA | NA | NA | ||||||||||||||
| 7lnm | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TRP | A:353 | B:388 | 30.0 | 0.118 | -155.7 | 125.3 | 30.0 | 0.118 | 0.0 |
HOH |
4.857 |
O |
O |
|||
| TRP | B:353 | C:388 | 32.0 | 0.125 | -145.2 | 119.2 | 32.0 | 0.125 | 0.0 |
HOH |
8.867 |
O |
O |
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| TRP | C:353 | E:388 | 29.0 | 0.114 | -158.2 | 126.4 | NA | NA | NA | ||||||||||||||
| TRP | D:353 | F:388 | 23.0 | 0.09 | -138.0 | 116.5 | NA | NA | NA | ||||||||||||||
| TRP | E:353 | I:388 | 31.0 | 0.122 | -147.6 | 121.9 | NA | NA | NA | ||||||||||||||
| TRP | F:353 | J:388 | 31.0 | 0.122 | -152.4 | 118.0 | NA | NA | NA | ||||||||||||||
| 7lom | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TRP | A:353 | A:388 | 20.0 | 0.078 | -158.9 | 174.9 | 20.0 | 0.078 | 0.0 |
HOH |
2.564 |
O |
O |
|||
| TRP | B:353 | B:388 | 18.0 | 0.071 | -160.7 | 176.3 | NA | NA | NA | ||||||||||||||
| TRP | C:353 | C:388 | 33.0 | 0.129 | -167.7 | 131.1 | NA | NA | NA | ||||||||||||||
| 7lon | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TRP | A:353 | B:388 | 22.0 | 0.086 | -127.9 | 155.3 | 22.0 | 0.086 | 0.0 | |||||||
| TRP | B:353 | A:388 | 20.0 | 0.078 | -124.8 | 155.9 | NA | NA | NA | ||||||||||||||
| TRP | C:353 | C:388 | 23.0 | 0.09 | -124.2 | 154.8 | NA | NA | NA | ||||||||||||||
| 1gbn | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | TRP | A:351 | A:388 | 14.0 | 0.055 | -82.9 | 163.8 | 14.0 | 0.055 | 0.0 |
HOH |
8.228 |
CB |
O |
|||
| TRP | B:351 | B:388 | 12.0 | 0.047 | -82.7 | 163.6 | 12.0 | 0.047 | 0.0 |
HOH |
9.641 |
CH2 |
O |
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| TRP | C:351 | C:388 | 14.0 | 0.055 | -82.6 | 164.4 | 14.0 | 0.055 | 0.0 | ||||||||||||||
| 2can | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | TRP | A:351 | A:388 | 11.0 | 0.043 | -103.9 | 169.3 | 11.0 | 0.043 | 0.0 | |||||||
| TRP | B:351 | B:388 | 11.0 | 0.043 | -104.2 | 169.0 | 11.0 | 0.043 | 0.0 | ||||||||||||||
| TRP | C:351 | C:388 | 11.0 | 0.043 | -103.8 | 169.3 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04181-f1 | 1 | P04181 | 100.0 | 0.0 | TRP | A:388 | A:388 | 31.0 | 0.122 | B | -134.7 | 118.0 | |