Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126090340 . G A CCDS7639.1:NM_000274.3:c.969taC>taT_NP_000265.1:p.323Y>Y Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 TYR A:323 A:323 121.0 0.526 S -85.4 -3.8 9.0 0.039 0.487 B:P04181:0.487
 PLP
HOH
 4.909
2.942
 CD1
N
 O1P
O
TYR B:323 B:323 122.0 0.53 S -83.1 -6.5 10.0 0.043 0.487 A:P04181:0.487
 PLP
HOH
 4.890
3.063
 CD1
N
 O1P
O
TYR C:323 C:323 120.0 0.522 S -85.3 -4.0 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 TYR A:323 A:323 119.0 0.517 S -87.9 -9.1 NA NA NA
TYR B:323 B:323 119.0 0.517 S -86.6 -11.0 NA NA NA
TYR C:323 C:323 119.0 0.517 S -85.5 -6.0 119.0 0.517 0.0 HOH
 2.887
 N
 O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 TYR A:323 A:323 123.0 0.535 S -87.0 -12.6 9.0 0.039 0.496 B:P04181:0.496
 PLP
HOH
 4.806
8.993
 CD1
OH
 O1P
O
TYR B:323 B:323 122.0 0.53 S -86.9 -14.1 7.0 0.03 0.5 A:P04181:0.5
 PLP
HOH
 4.760
4.795
 CD1
C
 O1P
O
TYR C:323 C:323 124.0 0.539 S -86.2 -14.4 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 TYR A:323 A:323 120.0 0.522 S -86.2 -6.3 10.0 0.043 0.479 B:P04181:0.478
 PLP
HOH
 4.769
2.964
 CD1
N
 O1P
O
TYR B:323 B:323 122.0 0.53 S -86.2 -9.2 9.0 0.039 0.491 A:P04181:0.491
 PLP
HOH
 4.704
3.001
 CD1
N
 O1P
O
TYR C:323 C:323 120.0 0.522 S -91.5 -6.1 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 TYR A:299 A:323 120.0 0.522 S -90.8 -13.1 10.0 0.043 0.479 A:P04181:0.478
 PLP
HOH
 4.922
2.896
 CD1
N
 O1P
O
TYR B:299 B:323 121.0 0.526 S -87.9 -11.8 NA NA NA
TYR C:299 C:323 119.0 0.517 S -89.7 -11.8 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 TYR A:288 A:323 123.0 0.535 S -87.6 -4.5 7.0 0.03 0.505 B:P04181:0.504
 9QJ
HOH
 4.829
2.865
 CD1
N
 O1P
O
TYR B:288 B:323 120.0 0.522 S -87.3 -6.2 7.0 0.03 0.492 A:P04181:0.491
 9QJ
HOH
 4.776
2.949
 CD1
N
 O3P
O
TYR C:288 C:323 116.0 0.504 S -87.4 -8.3 116.0 0.504 0.0 HOH
 3.404
 O
 O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 TYR A:288 A:323 120.0 0.522 S -92.8 -7.4 8.0 0.035 0.487 B:P04181:0.487
 PLP
MQ4
HOH
 4.802
6.070
2.887
 CD1
N
N
 O1P
O12
O
TYR B:288 B:323 122.0 0.53 S -91.8 -11.6 8.0 0.035 0.495 A:P04181:0.496
 PLP
HOH
 4.744
2.928
 CD1
N
 O3P
O
TYR C:288 C:323 122.0 0.53 S -91.3 -8.5 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:288 A:323 118.0 0.513 S -90.5 -10.3 7.0 0.03 0.483 A:P04181:0.483
 PLP
QRM
HOH
 4.823
5.933
2.923
 CD2
N
N
 O1P
C3
O
TYR B:288 B:323 118.0 0.513 S -88.7 -8.5 NA NA NA
TYR C:288 C:323 118.0 0.513 S -90.6 -9.6 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:288 A:323 123.0 0.535 S -88.6 -6.1 7.0 0.03 0.505 B:P04181:0.504
 PLP
O78
HOH
 4.680
6.646
2.889
 CD1
N
N
 O1P
O8
O
TYR B:288 B:323 120.0 0.522 S -86.1 -7.5 7.0 0.03 0.492 A:P04181:0.491
 PLP
O78
HOH
 4.772
6.635
2.875
 CD1
N
N
 O2P
O9
O
TYR C:288 C:323 121.0 0.526 S -86.9 -3.9 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 TYR A:288 A:323 122.0 0.53 S -96.1 -9.7 9.0 0.039 0.491 A:P04181:0.491
 IF1
HOH
 4.850
2.842
 CD1
N
 O16
O
TYR B:288 B:323 122.0 0.53 S -91.3 -5.8 NA NA NA
TYR C:288 C:323 120.0 0.522 S -89.6 -12.0 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:288 B:323 125.0 0.543 S -93.5 -3.3 9.0 0.039 0.504 B:P04181:0.504
 Y7S
HOH
 5.138
2.839
 CD1
N
 O43
O
TYR B:288 C:323 123.0 0.535 S -91.8 -10.0 9.0 0.039 0.496 A:P04181:0.496
 Y7S
HOH
 4.993
2.790
 CD1
N
 O41
O
TYR C:288 E:323 121.0 0.526 S -96.0 -3.1 NA NA NA
TYR D:288 F:323 121.0 0.526 S -96.7 -7.2 NA NA NA
TYR E:288 I:323 121.0 0.526 S -96.1 -4.3 NA NA NA
TYR F:288 J:323 123.0 0.535 T -88.9 -4.9 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:288 A:323 152.0 0.661 360.0 0.8 9.0 0.039 0.622 D:None:0.104
A:P04181:0.557
 Y8P
HOH
 4.914
2.748
 CD1
N
 O42
O
TYR B:288 B:323 150.0 0.652 360.0 -2.7 NA NA NA
TYR C:288 C:323 147.0 0.639 360.0 -5.6 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:288 B:323 147.0 0.639 360.0 -11.7 10.0 0.043 0.596 D:None:0.104
A:P04181:0.543
 7QP
HOH
 4.764
2.995
 CD1
OH
 O42
O
TYR B:288 A:323 144.0 0.626 360.0 -12.2 NA NA NA
TYR C:288 C:323 146.0 0.635 360.0 -13.1 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:286 A:323 123.0 0.535 S -85.4 -14.6 9.0 0.039 0.496 B:P04181:0.496
 GBC
PLP
HOH
 6.445
4.267
2.063
 H
H
H
 O2
O2P
O
TYR B:286 B:323 119.0 0.517 S -86.0 -13.7 9.0 0.039 0.478 A:P04181:0.478
 GAB
PLP
HOH
 6.579
4.173
2.017
 N
H
H
 C1'
O2P
O
TYR C:286 C:323 118.0 0.513 S -85.6 -15.1 118.0 0.513 0.0 HOH
 1.925
 H
 O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:286 A:323 121.0 0.526 S -82.8 -9.5 9.0 0.039 0.487 B:P04181:0.487
 CAN
PLP
HOH
 6.179
4.205
2.166
 N
H
H
 N
O2P
O
TYR B:286 B:323 120.0 0.522 S -82.6 -10.6 9.0 0.039 0.483 A:P04181:0.483
 CAN
PLP
HOH
 6.769
4.075
1.801
 H
H
H
 CG
O2P
O
TYR C:286 C:323 122.0 0.53 S -83.4 -8.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 TYR A:323 A:323 116.0 0.504 S -103.8 -15.0