Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126090354 . G A CCDS7639.1:NM_000274.3:c.955Cat>Tat_NP_000265.1:p.319H>Y Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 HIS A:319 A:319 45.0 0.231 S -160.6 152.2 3.0 0.015 0.216 B:P04181:0.215
 PLP
HOH
 9.257
3.105
 C
O
 O3P
O
HIS B:319 B:319 45.0 0.231 S -159.0 151.1 3.0 0.015 0.216 A:P04181:0.215
 PLP
HOH
 9.503
2.634
 C
O
 O3P
O
HIS C:319 C:319 47.0 0.241 S -163.0 147.3 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 HIS A:319 A:319 45.0 0.231 S -169.4 147.7 NA NA NA
HIS B:319 B:319 45.0 0.231 S -163.9 151.9 NA NA NA
HIS C:319 C:319 48.0 0.246 S -172.7 148.5 48.0 0.246 0.0 HOH
 2.488
 CE1
 O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 HIS A:319 A:319 44.0 0.226 S -165.9 151.3 1.0 0.005 0.221 B:P04181:0.221
 PLP
HOH
 9.068
9.936
 C
N
 O3P
O
HIS B:319 B:319 44.0 0.226 S -165.8 151.6 1.0 0.005 0.221 A:P04181:0.221
 PLP
HOH
 9.004
3.677
 C
C
 O3P
O
HIS C:319 C:319 45.0 0.231 S -166.7 151.9 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 HIS A:319 A:319 35.0 0.179 S -171.6 104.8 2.0 0.01 0.169 B:P04181:0.169
 PLP
HOH
 9.324
4.517
 NE2
CA
 O2P
O
HIS B:319 B:319 37.0 0.19 S -167.2 122.4 3.0 0.015 0.175 A:P04181:0.174
 PLP
HOH
 9.362
4.373
 C
CA
 O3P
O
HIS C:319 C:319 34.0 0.174 S -163.1 112.2 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 HIS A:295 A:319 42.0 0.215 S -162.3 111.9 4.0 0.021 0.194 A:P04181:0.195
 PLP
HOH
 8.793
2.968
 C
O
 O2P
O
HIS B:295 B:319 42.0 0.215 S -163.3 111.6 NA NA NA
HIS C:295 C:319 40.0 0.205 S -161.5 113.3 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 HIS A:284 A:319 47.0 0.241 S -169.7 147.2 4.0 0.021 0.22 B:P04181:0.221
 9QJ
HOH
 6.581
3.136
 C
O
 O2F
O
HIS B:284 B:319 49.0 0.251 S -171.2 149.2 5.0 0.026 0.225 A:P04181:0.226
 9QJ
HOH
 6.511
3.743
 C
CE1
 O1F
O
HIS C:284 C:319 48.0 0.246 S -170.4 143.7 48.0 0.246 0.0 HOH
 5.176
 O
 O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 HIS A:284 A:319 47.0 0.241 S -168.8 144.0 4.0 0.021 0.22 B:P04181:0.221
 PLP
MQ4
HOH
 9.074
6.091
2.787
 C
O
O
 O3P
O11
O
HIS B:284 B:319 49.0 0.251 S -166.5 149.7 4.0 0.021 0.23 A:P04181:0.231
 PLP
HOH
 9.115
2.871
 C
O
 O1P
O
HIS C:284 C:319 51.0 0.262 S -168.6 147.8 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 HIS A:284 A:319 52.0 0.267 S -166.6 153.8 2.0 0.01 0.257 A:P04181:0.256
 PLP
QRM
HOH
 9.109
6.051
2.838
 C
C
O
 O2P
O9
O
HIS B:284 B:319 51.0 0.262 S -166.5 153.4 NA NA NA
HIS C:284 C:319 51.0 0.262 S -168.3 155.5 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 HIS A:284 A:319 46.0 0.236 S -162.3 153.0 4.0 0.021 0.215 B:P04181:0.215
 PLP
O78
HOH
 9.234
5.324
2.966
 C
C
O
 O2P
O9
O
HIS B:284 B:319 48.0 0.246 S -161.5 153.2 2.0 0.01 0.236 A:P04181:0.236
 PLP
O78
HOH
 9.222
5.348
3.108
 CE1
C
O
 O1P
O8
O
HIS C:284 C:319 48.0 0.246 S -154.3 154.7 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 HIS A:284 A:319 50.0 0.256 S -171.5 149.1 3.0 0.015 0.241 A:P04181:0.241
 IF1
HOH
 5.895
2.694
 O
O
 O26
O
HIS B:284 B:319 47.0 0.241 S -172.4 145.5 NA NA NA
HIS C:284 C:319 48.0 0.246 S -171.9 150.4 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 HIS A:284 B:319 48.0 0.246 S -162.8 155.5 2.0 0.01 0.236 B:P04181:0.236
 Y7S
HOH
 7.543
2.647
 O
O
 O19
O
HIS B:284 C:319 50.0 0.256 S -169.8 159.9 2.0 0.01 0.246 A:P04181:0.246
 Y7S
HOH
 6.004
2.580
 O
O
 O19
O
HIS C:284 E:319 52.0 0.267 S -159.2 157.6 NA NA NA
HIS D:284 F:319 52.0 0.267 S -169.1 157.6 NA NA NA
HIS E:284 I:319 47.0 0.241 S -168.7 149.7 NA NA NA
HIS F:284 J:319 49.0 0.251 S -169.8 152.8 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 HIS A:284 A:319 44.0 0.226 S -170.0 149.9 2.0 0.01 0.216 A:P04181:0.215
 THR
Y8P
HOH
 8.319
9.210
4.184
 C
C
CA
 N
C10
O
HIS B:284 B:319 49.0 0.251 S -168.2 154.1 NA NA NA
HIS C:284 C:319 46.0 0.236 S -165.5 150.1 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 HIS A:284 B:319 48.0 0.246 S -170.2 150.4 2.0 0.01 0.236 A:P04181:0.236
 THR
7QP
HOH
 8.361
5.122
2.878
 C
C
O
 N
O05
O
HIS B:284 A:319 48.0 0.246 S -169.7 149.9 NA NA NA
HIS C:284 C:319 50.0 0.256 S -169.3 149.6 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 HIS A:282 A:319 46.0 0.236 S -164.5 146.2 2.0 0.01 0.226 B:P04181:0.226
 GBC
PLP
HOH
 5.673
8.864
2.975
 C
HE2
H
 O2
O1P
O
HIS B:282 B:319 46.0 0.236 S -164.0 147.6 2.0 0.01 0.226 A:P04181:0.226
 GAB
PLP
HOH
 5.593
8.791
2.972
 C
HE2
O
 O1'
O1P
O
HIS C:282 C:319 44.0 0.226 S -164.2 147.2 44.0 0.226 0.0 HOH
 2.779
 HE2
 O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 HIS A:282 A:319 47.0 0.241 S -174.9 144.9 2.0 0.01 0.231 F:None:0.015
B:P04181:0.226
 CAN
PLP
HOH
 4.682
8.718
4.108
 C
HE2
CA
 OXT
O1P
O
HIS B:282 B:319 48.0 0.246 S -174.8 144.8 2.0 0.01 0.236 D:None:0.026
A:P04181:0.236
 CAN
PLP
HOH
 4.284
8.803
2.439
 C
HE2
HE2
 OXT
O1P
O
HIS C:282 C:319 48.0 0.246 S -175.6 144.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 HIS A:319 A:319 41.0 0.21 S -149.9 148.6