Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126091497 . G A CCDS7639.1:NM_000274.3:c.899cCt>cTt_NP_000265.1:p.300P>L Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 PRO A:300 A:300 77.0 0.531 -78.0 106.7 0.0 0.0 0.531 B:P04181:0.531
 PLP
HOH
 7.019
2.853
 CB
O
 O1P
O
PRO B:300 B:300 76.0 0.524 -76.2 107.6 0.0 0.0 0.524 A:P04181:0.524
 PLP
HOH
 6.904
2.880
 CB
O
 O1P
O
PRO C:300 C:300 75.0 0.517 -79.6 105.1 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 PRO A:300 A:300 75.0 0.517 -75.7 106.8 NA NA NA
PRO B:300 B:300 74.0 0.51 -79.5 100.5 NA NA NA
PRO C:300 C:300 78.0 0.538 -72.9 105.7 78.0 0.538 0.0 PFM
PFM
HOH
 6.808
6.808
2.819
 CB
CB
O
 OP3
OP3
O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 PRO A:300 A:300 77.0 0.531 -71.8 102.5 0.0 0.0 0.531 B:P04181:0.531
 PLP
 6.989
 CB
 O1P
PRO B:300 B:300 78.0 0.538 -71.5 103.1 1.0 0.007 0.531 A:P04181:0.531
 PLP
 6.730
 CB
 O1P
PRO C:300 C:300 75.0 0.517 -71.8 101.8 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 PRO A:300 A:300 76.0 0.524 -76.0 107.1 1.0 0.007 0.517 B:P04181:0.517
 PLP
HOH
 6.788
2.804
 CB
O
 O1P
O
PRO B:300 B:300 77.0 0.531 -72.9 104.1 0.0 0.0 0.531 A:P04181:0.531
 PLP
HOH
 6.798
2.790
 CB
O
 O1P
O
PRO C:300 C:300 77.0 0.531 -76.1 106.7 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 PRO A:276 A:300 79.0 0.545 -76.1 103.4 0.0 0.0 0.545 A:P04181:0.545
 PLP
HOH
 6.895
2.724
 CB
O
 O1P
O
PRO B:276 B:300 79.0 0.545 -76.2 103.7 NA NA NA
PRO C:276 C:300 78.0 0.538 -76.3 104.1 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 PRO A:265 A:300 78.0 0.538 -76.6 105.0 1.0 0.007 0.531 B:P04181:0.531
 9QJ
HOH
 6.843
2.838
 CB
O
 O3P
O
PRO B:265 B:300 79.0 0.545 -75.5 106.2 0.0 0.0 0.545 A:P04181:0.545
 9QJ
HOH
 6.805
2.686
 CB
O
 O1P
O
PRO C:265 C:300 81.0 0.559 -78.4 106.5 81.0 0.559 0.0 9QJ
HOH
 6.786
2.944
 CB
O
 O3P
O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 PRO A:265 A:300 80.0 0.552 -72.4 107.2 0.0 0.0 0.552 B:P04181:0.552
 PLP
HOH
 6.722
2.710
 CB
O
 O3P
O
PRO B:265 B:300 78.0 0.538 -73.6 106.6 0.0 0.0 0.538 A:P04181:0.538
 PLP
HOH
 6.702
2.720
 CB
O
 O1P
O
PRO C:265 C:300 80.0 0.552 -77.1 104.8 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 PRO A:265 A:300 79.0 0.545 -74.3 102.3 0.0 0.0 0.545 A:P04181:0.545
 PLP
HOH
 6.858
2.662
 CB
O
 O1P
O
PRO B:265 B:300 78.0 0.538 -73.9 103.2 NA NA NA
PRO C:265 C:300 78.0 0.538 -74.0 102.9 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 PRO A:265 A:300 78.0 0.538 -75.3 102.4 0.0 0.0 0.538 B:P04181:0.538
 PLP
HOH
 6.792
2.637
 CB
O
 O2P
O
PRO B:265 B:300 77.0 0.531 -68.9 102.4 0.0 0.0 0.531 A:P04181:0.531
 PLP
HOH
 6.762
2.883
 CB
O
 O1P
O
PRO C:265 C:300 76.0 0.524 -72.5 105.6 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 PRO A:265 A:300 80.0 0.552 -76.7 105.3 0.0 0.0 0.552 A:P04181:0.552
 IF1
HOH
 6.671
2.840
 CB
O
 O16
O
PRO B:265 B:300 83.0 0.572 -75.5 107.7 NA NA NA
PRO C:265 C:300 80.0 0.552 -74.6 104.7 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 PRO A:265 B:300 80.0 0.552 -70.1 106.5 0.0 0.0 0.552 B:P04181:0.552
 Y7S
HOH
 6.960
2.668
 CB
O
 O41
O
PRO B:265 C:300 78.0 0.538 -69.9 105.4 0.0 0.0 0.538 A:P04181:0.538
 Y7S
HOH
 7.158
2.855
 CB
O
 O43
O
PRO C:265 E:300 81.0 0.559 -69.5 106.2 NA NA NA
PRO D:265 F:300 79.0 0.545 -70.4 105.0 NA NA NA
PRO E:265 I:300 79.0 0.545 -72.4 104.8 NA NA NA
PRO F:265 J:300 79.0 0.545 -72.8 107.1 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 PRO A:265 A:300 77.0 0.531 -74.0 104.1 1.0 0.007 0.524 A:P04181:0.524
 THR
Y8P
THR
HOH
 7.520
6.848
9.412
2.921
 CG
CB
O
O
 C
O42
C
O
PRO B:265 B:300 77.0 0.531 -71.8 105.7 NA NA NA
PRO C:265 C:300 78.0 0.538 -73.8 103.2 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 PRO A:265 B:300 77.0 0.531 -73.2 103.6 0.0 0.0 0.531 A:P04181:0.531
 THR
7QP
THR
HOH
 7.588
6.814
9.537
2.697
 CG
CB
O
O
 C
O42
C
O
PRO B:265 A:300 78.0 0.538 -71.9 104.6 NA NA NA
PRO C:265 C:300 77.0 0.531 -73.2 105.6 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 PRO A:263 A:300 80.0 0.552 -74.0 102.9 1.0 0.007 0.545 B:P04181:0.545
 PLP
HOH
 6.930
4.081
 CB
C
 O2P
O
PRO B:263 B:300 80.0 0.552 -73.7 102.7 1.0 0.007 0.545 A:P04181:0.545
 PLP
HOH
 6.879
2.725
 CB
O
 O2P
O
PRO C:263 C:300 78.0 0.538 -74.9 102.8 78.0 0.538 0.0 PLP
HOH
 6.875
2.776
 CB
O
 O2P
O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 PRO A:263 A:300 80.0 0.552 -73.6 105.3 0.0 0.0 0.552 B:P04181:0.552
 PLP
HOH
 7.130
2.655
 CB
O
 O2P
O
PRO B:263 B:300 78.0 0.538 -73.7 105.0 1.0 0.007 0.531 A:P04181:0.531
 PLP
HOH
 7.129
2.887
 CB
O
 O2P
O
PRO C:263 C:300 79.0 0.545 -73.6 105.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 PRO A:300 A:300 81.0 0.559 -67.5 106.0