Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126091499 . G A CCDS7639.1:NM_000274.3:c.897taC>taT_NP_000265.1:p.299Y>Y Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 TYR A:299 A:299 45.0 0.196 S -169.7 146.9 1.0 0.004 0.192 B:P04181:0.191
 PLP
HOH
 8.715
2.633
 O
OH
 O1P
O
TYR B:299 B:299 46.0 0.2 S -166.7 145.7 0.0 0.0 0.2 A:P04181:0.2
 PLP
HOH
 8.715
2.609
 O
OH
 O1P
O
TYR C:299 C:299 45.0 0.196 S -166.7 148.2 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 TYR A:299 A:299 45.0 0.196 S -172.9 142.3 NA NA NA
TYR B:299 B:299 44.0 0.191 S -168.5 146.3 NA NA NA
TYR C:299 C:299 40.0 0.174 S -170.7 139.6 40.0 0.174 0.0 PFM
PFM
HOH
 8.976
8.976
3.359
 O
O
CE1
 OP3
OP3
O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 TYR A:299 A:299 40.0 0.174 S -162.2 140.8 0.0 0.0 0.174 B:P04181:0.174
 PLP
 8.802
 O
 O1P
TYR B:299 B:299 42.0 0.183 S -162.7 140.4 0.0 0.0 0.183 A:P04181:0.183
 PLP
 8.631
 O
 O1P
TYR C:299 C:299 41.0 0.178 S -162.1 140.7 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 TYR A:299 A:299 46.0 0.2 S -169.5 143.3 0.0 0.0 0.2 B:P04181:0.2
 PLP
HOH
 8.696
2.664
 O
OH
 O1P
O
TYR B:299 B:299 43.0 0.187 S -171.1 140.4 0.0 0.0 0.187 A:P04181:0.187
 PLP
HOH
 8.720
2.665
 O
OH
 O1P
O
TYR C:299 C:299 42.0 0.183 S -168.9 140.1 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 TYR A:275 A:299 43.0 0.187 S -169.3 140.0 0.0 0.0 0.187 A:P04181:0.187
 PLP
HOH
 8.947
2.721
 O
OH
 O1P
O
TYR B:275 B:299 43.0 0.187 S -171.4 140.9 NA NA NA
TYR C:275 C:299 43.0 0.187 S -169.4 139.3 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 TYR A:264 A:299 43.0 0.187 S -168.3 141.2 0.0 0.0 0.187 B:P04181:0.187
 9QJ
HOH
 8.742
2.687
 O
OH
 O3P
O
TYR B:264 B:299 43.0 0.187 S -168.8 138.8 1.0 0.004 0.183 A:P04181:0.183
 9QJ
HOH
 8.791
2.709
 O
OH
 O1P
O
TYR C:264 C:299 44.0 0.191 S -169.3 139.9 44.0 0.191 0.0 9QJ
HOH
 8.692
2.684
 O
OH
 O3P
O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 TYR A:264 A:299 42.0 0.183 S -171.7 137.3 1.0 0.004 0.179 B:P04181:0.178
 PLP
HOH
 8.809
2.629
 O
OH
 O3P
O
TYR B:264 B:299 43.0 0.187 S -167.5 139.6 1.0 0.004 0.183 A:P04181:0.183
 PLP
HOH
 8.768
2.506
 O
OH
 O1P
O
TYR C:264 C:299 43.0 0.187 S -166.9 142.5 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:264 A:299 41.0 0.178 S -167.7 142.3 0.0 0.0 0.178 A:P04181:0.178
 PLP
HOH
 8.725
2.663
 O
OH
 O1P
O
TYR B:264 B:299 43.0 0.187 S -167.9 141.8 NA NA NA
TYR C:264 C:299 40.0 0.174 S -165.6 143.5 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:264 A:299 41.0 0.178 S -168.8 142.0 0.0 0.0 0.178 B:P04181:0.178
 PLP
HOH
 8.670
2.631
 O
OH
 O2P
O
TYR B:264 B:299 41.0 0.178 S -169.6 136.8 0.0 0.0 0.178 A:P04181:0.178
 PLP
HOH
 8.658
2.711
 O
OH
 O1P
O
TYR C:264 C:299 42.0 0.183 S -164.5 140.9 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 TYR A:264 A:299 42.0 0.183 S -169.3 139.0 0.0 0.0 0.183 A:P04181:0.183
 IF1
HOH
 8.755
2.484
 O
OH
 O16
O
TYR B:264 B:299 44.0 0.191 S -167.0 139.0 NA NA NA
TYR C:264 C:299 42.0 0.183 S -168.8 138.0 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:264 B:299 42.0 0.183 S -169.5 138.7 0.0 0.0 0.183 B:P04181:0.183
 Y7S
HOH
 8.976
2.378
 O
OH
 O41
O
TYR B:264 C:299 41.0 0.178 S -167.9 137.6 0.0 0.0 0.178 A:P04181:0.178
 Y7S
HOH
 9.134
2.730
 O
OH
 O43
O
TYR C:264 E:299 43.0 0.187 S -166.9 138.6 NA NA NA
TYR D:264 F:299 43.0 0.187 S -166.9 137.9 NA NA NA
TYR E:264 I:299 40.0 0.174 S -164.6 140.1 NA NA NA
TYR F:264 J:299 41.0 0.178 S -165.1 141.5 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:264 A:299 44.0 0.191 S -167.4 142.2 0.0 0.0 0.191 A:P04181:0.191
 THR
Y8P
THR
HOH
 9.062
8.708
7.527
3.355
 O
O
OH
CE1
 C
O42
O
O
TYR B:264 B:299 42.0 0.183 S -164.6 140.3 NA NA NA
TYR C:264 C:299 43.0 0.187 S -166.2 141.5 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:264 B:299 43.0 0.187 S -169.3 139.7 0.0 0.0 0.187 A:P04181:0.187
 THR
7QP
THR
HOH
 8.959
8.653
7.659
2.582
 O
O
OH
OH
 CB
O42
C
O
TYR B:264 A:299 44.0 0.191 S -166.4 139.9 NA NA NA
TYR C:264 C:299 41.0 0.178 S -168.5 140.4 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:262 A:299 43.0 0.187 S -169.3 142.5 0.0 0.0 0.187 B:P04181:0.187
 PLP
HOH
 8.744
1.832
 O
HH
 O2P
O
TYR B:262 B:299 40.0 0.174 S -169.9 142.2 0.0 0.0 0.174 A:P04181:0.174
 PLP
HOH
 8.658
1.968
 O
HH
 O2P
O
TYR C:262 C:299 43.0 0.187 S -169.5 142.5 43.0 0.187 0.0 PLP
HOH
 8.718
2.275
 O
HH
 O2P
O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:262 A:299 45.0 0.196 S -165.1 142.6 1.0 0.004 0.192 B:P04181:0.191
 PLP
HOH
 8.914
1.907
 O
HH
 O2P
O
TYR B:262 B:299 43.0 0.187 S -164.9 142.9 0.0 0.0 0.187 A:P04181:0.187
 PLP
HOH
 8.963
2.279
 O
HH
 O2P
O
TYR C:262 C:299 45.0 0.196 S -165.1 142.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 TYR A:299 A:299 52.0 0.226 S -155.7 141.9