Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 126091515 | . | A | C | CCDS7639.1:NM_000274.3:c.881cTt>cGt_NP_000265.1:p.294L>R | Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-04-01 | LEU | A:294 | A:294 | 0.0 | 0.0 | G | -64.1 | -14.0 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.785 4.326 |
N N |
O1P O |
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| LEU | B:294 | B:294 | 0.0 | 0.0 | G | -61.5 | -13.8 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.865 4.401 |
N N |
O1P O |
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| LEU | C:294 | C:294 | 0.0 | 0.0 | G | -62.4 | -14.1 | NA | NA | NA | |||||||||||||
| 2oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-12-09 | LEU | A:294 | A:294 | 0.0 | 0.0 | G | -55.0 | -22.2 | NA | NA | NA | ||||||
| LEU | B:294 | B:294 | 0.0 | 0.0 | G | -60.3 | -19.6 | NA | NA | NA | |||||||||||||
| LEU | C:294 | C:294 | 0.0 | 0.0 | G | -55.6 | -20.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.456 |
CD2 |
O |
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| 2byj | 1 | P04181 | 99.77 | 0.0 |
X-RAY |
2005-09-07 | LEU | A:294 | A:294 | 0.0 | 0.0 | G | -53.6 | -17.5 | 0.0 | 0.0 | 0.0 |
HOH |
9.568 |
O |
O |
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| LEU | B:294 | B:294 | 0.0 | 0.0 | G | -53.1 | -18.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.997 |
N |
O |
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| LEU | C:294 | C:294 | 0.0 | 0.0 | G | -53.5 | -17.7 | NA | NA | NA | |||||||||||||
| 2byl | 1 | P04181 | 99.32 | 0.0 |
X-RAY |
2005-09-07 | LEU | A:294 | A:294 | 1.0 | 0.006 | G | -56.3 | -26.3 | 1.0 | 0.006 | 0.0 |
PLP HOH |
9.700 4.374 |
N CB |
O1P O |
||
| LEU | B:294 | B:294 | 0.0 | 0.0 | G | -52.4 | -25.2 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.801 4.403 |
N N |
O1P O |
|||||||||
| LEU | C:294 | C:294 | 0.0 | 0.0 | G | -58.6 | -22.3 | NA | NA | NA | |||||||||||||
| 6hx7 | 1 | P04181 | 99.76 | 0.0 |
X-RAY |
2019-06-05 | LEU | A:270 | A:294 | 0.0 | 0.0 | G | -54.6 | -18.5 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.908 4.317 |
N CB |
O1P O |
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| LEU | B:270 | B:294 | 0.0 | 0.0 | G | -54.6 | -17.0 | NA | NA | NA | |||||||||||||
| LEU | C:270 | C:294 | 0.0 | 0.0 | G | -54.3 | -17.3 | NA | NA | NA | |||||||||||||
| 5vwo | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2017-08-30 | LEU | A:259 | A:294 | 0.0 | 0.0 | G | -57.9 | -17.4 | 0.0 | 0.0 | 0.0 |
9QJ HOH |
9.901 4.354 |
N CD2 |
O3P O |
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| LEU | B:259 | B:294 | 0.0 | 0.0 | G | -58.9 | -18.5 | 0.0 | 0.0 | 0.0 |
9QJ HOH |
9.830 4.422 |
N N |
O1P O |
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| LEU | C:259 | C:294 | 0.0 | 0.0 | G | -57.9 | -19.4 | 0.0 | 0.0 | 0.0 |
9QJ HOH |
9.811 4.327 |
N N |
O3P O |
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| 6oia | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | LEU | A:259 | A:294 | 0.0 | 0.0 | G | -56.9 | -19.1 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.951 4.417 |
N CD2 |
O3P O |
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| LEU | B:259 | B:294 | 0.0 | 0.0 | G | -58.6 | -19.5 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.926 4.391 |
N N |
O1P O |
|||||||||
| LEU | C:259 | C:294 | 0.0 | 0.0 | G | -50.9 | -22.1 | NA | NA | NA | |||||||||||||
| 6v8c | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | LEU | A:259 | A:294 | 0.0 | 0.0 | G | -55.0 | -18.2 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.942 4.393 |
N CB |
O1P O |
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| LEU | B:259 | B:294 | 0.0 | 0.0 | G | -56.8 | -21.0 | NA | NA | NA | |||||||||||||
| LEU | C:259 | C:294 | 0.0 | 0.0 | G | -56.9 | -16.9 | NA | NA | NA | |||||||||||||
| 6v8d | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | LEU | A:259 | A:294 | 0.0 | 0.0 | G | -56.0 | -16.3 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.805 4.366 |
N CD2 |
O2P O |
||
| LEU | B:259 | B:294 | 0.0 | 0.0 | G | -57.0 | -13.6 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.756 4.316 |
N N |
O1P O |
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| LEU | C:259 | C:294 | 0.0 | 0.0 | G | -57.1 | -15.7 | NA | NA | NA | |||||||||||||
| 7jx9 | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-01-06 | LEU | A:259 | A:294 | 0.0 | 0.0 | G | -60.0 | -15.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.425 |
N |
O |
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| LEU | B:259 | B:294 | 0.0 | 0.0 | G | -60.0 | -11.0 | NA | NA | NA | |||||||||||||
| LEU | C:259 | C:294 | 0.0 | 0.0 | G | -55.7 | -20.6 | NA | NA | NA | |||||||||||||
| 7lnm | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | LEU | A:259 | B:294 | 0.0 | 0.0 | G | -54.9 | -19.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.434 |
CD2 |
O |
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| LEU | B:259 | C:294 | 0.0 | 0.0 | G | -55.9 | -20.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.366 |
CD2 |
O |
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| LEU | C:259 | E:294 | 0.0 | 0.0 | G | -57.1 | -17.0 | NA | NA | NA | |||||||||||||
| LEU | D:259 | F:294 | 0.0 | 0.0 | G | -55.7 | -21.7 | NA | NA | NA | |||||||||||||
| LEU | E:259 | I:294 | 0.0 | 0.0 | G | -53.2 | -18.3 | NA | NA | NA | |||||||||||||
| LEU | F:259 | J:294 | 0.0 | 0.0 | G | -55.1 | -19.0 | NA | NA | NA | |||||||||||||
| 7lom | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | LEU | A:259 | A:294 | 0.0 | 0.0 | G | -54.8 | -20.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.256 |
CB |
O |
||
| LEU | B:259 | B:294 | 0.0 | 0.0 | G | -58.1 | -22.6 | NA | NA | NA | |||||||||||||
| LEU | C:259 | C:294 | 0.0 | 0.0 | G | -57.8 | -19.1 | NA | NA | NA | |||||||||||||
| 7lon | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | LEU | A:259 | B:294 | 0.0 | 0.0 | G | -57.2 | -14.7 | 0.0 | 0.0 | 0.0 |
7QP HOH |
9.894 4.390 |
N CD2 |
O42 O |
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| LEU | B:259 | A:294 | 0.0 | 0.0 | G | -55.5 | -12.9 | NA | NA | NA | |||||||||||||
| LEU | C:259 | C:294 | 0.0 | 0.0 | G | -55.9 | -11.6 | NA | NA | NA | |||||||||||||
| 1gbn | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | LEU | A:257 | A:294 | 0.0 | 0.0 | G | -61.5 | -13.8 | 0.0 | 0.0 | 0.0 |
PLP HOH |
8.993 3.748 |
H H |
O2P O |
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| LEU | B:257 | B:294 | 0.0 | 0.0 | G | -61.1 | -14.1 | 0.0 | 0.0 | 0.0 |
PLP HOH |
8.842 3.952 |
H H |
O2P O |
|||||||||
| LEU | C:257 | C:294 | 0.0 | 0.0 | G | -61.7 | -14.4 | 0.0 | 0.0 | 0.0 |
PLP HOH |
8.989 4.017 |
H H |
O2P O |
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| 2can | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | LEU | A:257 | A:294 | 0.0 | 0.0 | G | -61.9 | -13.9 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.130 3.877 |
H H |
O2P O |
||
| LEU | B:257 | B:294 | 0.0 | 0.0 | G | -61.3 | -14.2 | 0.0 | 0.0 | 0.0 |
PLP HOH |
9.151 4.019 |
H H |
O2P O |
|||||||||
| LEU | C:257 | C:294 | 0.0 | 0.0 | G | -61.0 | -14.0 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04181-f1 | 1 | P04181 | 100.0 | 0.0 | LEU | A:294 | A:294 | 0.0 | 0.0 | G | -56.9 | -20.8 | |