Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 126091521 | . | T | A | CCDS7639.1:NM_000274.3:c.875aAg>aTg_NP_000265.1:p.292K>M | Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-04-01 | LYS | A:292 | A:292 | 61.0 | 0.305 | G | 41.0 | -95.4 | 17.0 | 0.085 | 0.22 |
B:P04181:0.22 |
PLP HOH |
1.458 2.554 |
NZ O |
C4A O |
|
| LYS | B:292 | B:292 | 60.0 | 0.3 | G | 41.5 | -96.8 | 17.0 | 0.085 | 0.215 |
A:P04181:0.215 |
PLP HOH |
1.454 2.703 |
NZ O |
C4A O |
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| LYS | C:292 | C:292 | 60.0 | 0.3 | G | 40.8 | -95.3 | NA | NA | NA | |||||||||||||
| 2oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-12-09 | LYS | A:292 | A:292 | 67.0 | 0.335 | G | 38.5 | -98.6 | NA | NA | NA | ||||||
| LYS | B:292 | B:292 | 66.0 | 0.33 | G | 41.7 | -99.8 | NA | NA | NA | |||||||||||||
| LYS | C:292 | C:292 | 64.0 | 0.32 | G | 43.4 | -93.8 | 64.0 | 0.32 | 0.0 |
PFM PFM HOH |
3.145 3.145 2.919 |
NZ NZ O |
C4B C4B O |
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| 2byj | 1 | P04181 | 99.77 | 0.0 |
X-RAY |
2005-09-07 | LYS | A:292 | A:292 | 70.0 | 0.35 | G | 47.1 | -88.0 | 23.0 | 0.115 | 0.235 |
B:P04181:0.235 |
PLP HOH |
1.424 8.878 |
NZ NZ |
C4A O |
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| LYS | B:292 | B:292 | 69.0 | 0.345 | G | 46.1 | -88.1 | 23.0 | 0.115 | 0.23 |
A:P04181:0.23 |
PLP HOH |
1.402 4.935 |
NZ CB |
C4A O |
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| LYS | C:292 | C:292 | 69.0 | 0.345 | G | 46.6 | -87.4 | NA | NA | NA | |||||||||||||
| 2byl | 1 | P04181 | 99.32 | 0.0 |
X-RAY |
2005-09-07 | LYS | A:292 | A:292 | 64.0 | 0.32 | G | 44.9 | -95.3 | 18.0 | 0.09 | 0.23 |
B:P04181:0.23 |
PLP HOH |
1.395 2.840 |
NZ N |
C4A O |
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| LYS | B:292 | B:292 | 62.0 | 0.31 | G | 43.0 | -90.9 | 18.0 | 0.09 | 0.22 |
A:P04181:0.22 |
PLP HOH |
1.392 2.887 |
NZ O |
C4A O |
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| LYS | C:292 | C:292 | 62.0 | 0.31 | G | 45.0 | -89.0 | NA | NA | NA | |||||||||||||
| 6hx7 | 1 | P04181 | 99.76 | 0.0 |
X-RAY |
2019-06-05 | LYS | A:268 | A:292 | 61.0 | 0.305 | G | 47.5 | -101.3 | 18.0 | 0.09 | 0.215 |
A:P04181:0.215 |
PLP HOH |
2.387 2.909 |
NZ O |
C4A O |
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| LYS | B:268 | B:292 | 59.0 | 0.295 | G | 45.9 | -100.6 | NA | NA | NA | |||||||||||||
| LYS | C:268 | C:292 | 65.0 | 0.325 | G | 49.3 | -103.1 | NA | NA | NA | |||||||||||||
| 5vwo | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2017-08-30 | LYS | A:257 | A:292 | 81.0 | 0.405 | G | 45.0 | -93.5 | 35.0 | 0.175 | 0.23 |
B:P04181:0.23 |
9QJ HOH |
1.490 2.863 |
NZ N |
C4A O |
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| LYS | B:257 | B:292 | 80.0 | 0.4 | G | 44.9 | -95.1 | 36.0 | 0.18 | 0.22 |
A:P04181:0.22 |
9QJ HOH |
1.497 2.873 |
NZ N |
C4A O |
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| LYS | C:257 | C:292 | 77.0 | 0.385 | G | 45.7 | -90.0 | 77.0 | 0.385 | 0.0 |
9QJ HOH |
1.490 2.887 |
NZ N |
C4A O |
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| 6oia | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | LYS | A:257 | A:292 | 70.0 | 0.35 | G | 39.6 | -93.1 | 25.0 | 0.125 | 0.225 |
B:P04181:0.225 |
PLP HOH |
2.653 2.844 |
NZ N |
O3 O |
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| LYS | B:257 | B:292 | 70.0 | 0.35 | G | 41.2 | -93.0 | 24.0 | 0.12 | 0.23 |
A:P04181:0.23 |
PLP MQ4 HOH |
2.850 1.470 2.864 |
NZ NZ N |
O3 C9 O |
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| LYS | C:257 | C:292 | 76.0 | 0.38 | G | 42.3 | -92.2 | NA | NA | NA | |||||||||||||
| 6v8c | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | LYS | A:257 | A:292 | 73.0 | 0.365 | G | 49.0 | -95.9 | 22.0 | 0.11 | 0.255 |
A:P04181:0.255 |
PLP QRM HOH |
3.598 1.459 2.961 |
CE NZ N |
C4A C5 O |
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| LYS | B:257 | B:292 | 70.0 | 0.35 | G | 45.0 | -97.6 | NA | NA | NA | |||||||||||||
| LYS | C:257 | C:292 | 71.0 | 0.355 | G | 46.6 | -97.6 | NA | NA | NA | |||||||||||||
| 6v8d | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | LYS | A:257 | A:292 | 77.0 | 0.385 | G | 44.1 | -91.8 | 35.0 | 0.175 | 0.21 |
B:P04181:0.21 |
PLP O78 HOH |
1.248 2.299 2.858 |
NZ NZ O |
C4A C5 O |
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| LYS | B:257 | B:292 | 86.0 | 0.43 | G | 45.8 | -88.4 | 41.0 | 0.205 | 0.225 |
A:P04181:0.225 |
PLP O78 HOH |
0.937 2.444 2.847 |
NZ NZ O |
C4A C5 O |
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| LYS | C:257 | C:292 | 83.0 | 0.415 | G | 47.3 | -86.0 | NA | NA | NA | |||||||||||||
| 7jx9 | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-01-06 | LYS | A:257 | A:292 | 73.0 | 0.365 | G | 39.9 | -94.5 | 29.0 | 0.145 | 0.22 |
A:P04181:0.22 |
IF1 HOH |
2.405 2.974 |
NZ O |
F31 O |
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| LYS | B:257 | B:292 | 77.0 | 0.385 | G | 35.3 | -90.5 | NA | NA | NA | |||||||||||||
| LYS | C:257 | C:292 | 69.0 | 0.345 | G | 38.0 | -98.0 | NA | NA | NA | |||||||||||||
| 7lnm | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | LYS | A:257 | B:292 | 78.0 | 0.39 | G | 46.6 | -93.6 | 23.0 | 0.115 | 0.275 |
B:P04181:0.275 |
Y7S HOH |
1.285 2.821 |
NZ O |
C17 O |
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| LYS | B:257 | C:292 | 80.0 | 0.4 | G | 51.7 | -93.3 | 25.0 | 0.125 | 0.275 |
A:P04181:0.275 |
Y7S HOH |
1.301 2.797 |
NZ N |
C17 O |
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| LYS | C:257 | E:292 | 77.0 | 0.385 | G | 39.9 | -92.2 | NA | NA | NA | |||||||||||||
| LYS | D:257 | F:292 | 81.0 | 0.405 | G | 38.3 | -92.3 | NA | NA | NA | |||||||||||||
| LYS | E:257 | I:292 | 76.0 | 0.38 | G | 51.2 | -97.2 | NA | NA | NA | |||||||||||||
| LYS | F:257 | J:292 | 76.0 | 0.38 | G | 41.6 | -93.7 | NA | NA | NA | |||||||||||||
| 7lom | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | LYS | A:257 | A:292 | 46.0 | 0.23 | G | 50.1 | -92.4 | 31.0 | 0.155 | 0.075 |
THR Y8P HOH |
2.453 1.301 2.948 |
NZ NZ O |
OG1 C21 O |
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| LYS | B:257 | B:292 | 45.0 | 0.225 | G | 39.9 | -97.3 | NA | NA | NA | |||||||||||||
| LYS | C:257 | C:292 | 39.0 | 0.195 | G | 55.2 | -100.4 | NA | NA | NA | |||||||||||||
| 7lon | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | LYS | A:257 | B:292 | 40.0 | 0.2 | G | 43.9 | -97.1 | 27.0 | 0.135 | 0.065 |
THR 7QP HOH |
2.417 1.290 2.779 |
NZ NZ N |
OG1 C21 O |
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| LYS | B:257 | A:292 | 37.0 | 0.185 | G | 45.7 | -94.9 | NA | NA | NA | |||||||||||||
| LYS | C:257 | C:292 | 42.0 | 0.21 | G | 57.8 | -102.1 | NA | NA | NA | |||||||||||||
| 1gbn | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | LYS | A:255 | A:292 | 73.0 | 0.365 | G | 39.1 | -94.2 | 25.0 | 0.125 | 0.24 |
B:P04181:0.24 |
GAB PLP HOH |
1.879 2.529 2.771 |
HZ3 HZ3 O |
N3 C4A O |
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| LYS | B:255 | B:292 | 68.0 | 0.34 | G | 38.5 | -94.3 | 23.0 | 0.115 | 0.225 |
A:P04181:0.225 |
GBC PLP HOH |
1.978 2.531 2.817 |
HZ3 HZ3 O |
N3 C4A O |
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| LYS | C:255 | C:292 | 72.0 | 0.36 | G | 38.7 | -94.4 | 72.0 | 0.36 | 0.0 |
GBC PLP HOH |
1.860 2.630 1.890 |
HZ3 HZ3 H |
N3 C4A O |
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| 2can | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | LYS | A:255 | A:292 | 49.0 | 0.245 | G | 39.4 | -90.8 | 13.0 | 0.065 | 0.18 |
B:P04181:0.11 |
CAN PLP HOH |
2.751 2.239 3.082 |
HZ3 HZ3 O |
OG C4A O |
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| LYS | B:255 | B:292 | 48.0 | 0.24 | G | 38.6 | -92.1 | 11.0 | 0.055 | 0.185 |
A:P04181:0.11 |
CAN PLP HOH |
2.007 2.763 3.437 |
HZ3 HZ3 CB |
NZ C4A O |
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| LYS | C:255 | C:292 | 48.0 | 0.24 | G | 39.1 | -91.2 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04181-f1 | 1 | P04181 | 100.0 | 0.0 | LYS | A:292 | A:292 | 60.0 | 0.3 | G | 48.5 | -101.2 | |