Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126091572 . C A CCDS7639.1:NM_000274.3:c.824tGg>tTg_NP_000265.1:p.275W>L Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 TRP A:275 A:275 64.0 0.251 S -58.9 -39.8 64.0 0.251 0.0 HOH
 3.526
 CB
 O
TRP B:275 B:275 65.0 0.255 S -58.3 -38.8 65.0 0.255 0.0 HOH
 3.006
 N
 O
TRP C:275 C:275 61.0 0.239 S -62.0 -38.2 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 TRP A:275 A:275 59.0 0.231 S -59.2 -43.6 NA NA NA
TRP B:275 B:275 61.0 0.239 S -57.4 -43.2 NA NA NA
TRP C:275 C:275 58.0 0.227 S -59.6 -43.1 58.0 0.227 0.0 HOH
 3.816
 NE1
 O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 TRP A:275 A:275 57.0 0.224 S -55.3 -47.5 57.0 0.224 0.0 HOH
 4.417
 CB
 O
TRP B:275 B:275 58.0 0.227 S -54.5 -47.5 58.0 0.227 0.0 HOH
 4.378
 CB
 O
TRP C:275 C:275 56.0 0.22 S -54.2 -48.3 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 TRP A:275 A:275 57.0 0.224 S -52.5 -42.0 57.0 0.224 0.0 HOH
 4.104
 O
 O
TRP B:275 B:275 54.0 0.212 S -54.0 -44.9 54.0 0.212 0.0 HOH
 3.000
 CD2
 O
TRP C:275 C:275 52.0 0.204 S -57.3 -47.0 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 TRP A:251 A:275 60.0 0.235 S -55.1 -48.2 60.0 0.235 0.0 HOH
 2.928
 N
 O
TRP B:251 B:275 73.0 0.286 S -58.8 -47.1 NA NA NA
TRP C:251 C:275 64.0 0.251 S -58.8 -44.4 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 TRP A:240 A:275 57.0 0.224 S -57.9 -43.9 57.0 0.224 0.0 HOH
 2.820
 NE1
 O
TRP B:240 B:275 60.0 0.235 S -56.0 -41.3 60.0 0.235 0.0 HOH
 3.292
 NE1
 O
TRP C:240 C:275 55.0 0.216 S -54.0 -42.6 55.0 0.216 0.0 HOH
 2.910
 N
 O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 TRP A:240 A:275 59.0 0.231 S -53.2 -43.9 59.0 0.231 0.0 HOH
 2.880
 N
 O
TRP B:240 B:275 56.0 0.22 S -56.2 -42.6 56.0 0.22 0.0 HOH
 2.912
 N
 O
TRP C:240 C:275 54.0 0.212 S -56.2 -41.8 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TRP A:240 A:275 49.0 0.192 S -54.2 -45.1 49.0 0.192 0.0 HOH
 3.226
 NE1
 O
TRP B:240 B:275 68.0 0.267 S -53.3 -45.7 NA NA NA
TRP C:240 C:275 67.0 0.263 S -53.5 -45.1 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TRP A:240 A:275 62.0 0.243 S -53.7 -40.8 62.0 0.243 0.0 HOH
 3.560
 NE1
 O
TRP B:240 B:275 64.0 0.251 S -53.3 -49.1 64.0 0.251 0.0 HOH
 3.426
 N
 O
TRP C:240 C:275 66.0 0.259 S -50.9 -52.4 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 TRP A:240 A:275 65.0 0.255 S -59.4 -43.2 65.0 0.255 0.0 HOH
 3.294
 CD1
 O
TRP B:240 B:275 54.0 0.212 S -54.5 -41.8 NA NA NA
TRP C:240 C:275 71.0 0.278 S -53.9 -36.1 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TRP A:240 B:275 58.0 0.227 S -54.0 -43.4 58.0 0.227 0.0 HOH
 2.731
 N
 O
TRP B:240 C:275 67.0 0.263 S -53.6 -43.7 67.0 0.263 0.0 HOH
 3.362
 N
 O
TRP C:240 E:275 57.0 0.224 S -53.9 -43.3 NA NA NA
TRP D:240 F:275 66.0 0.259 S -55.5 -44.3 NA NA NA
TRP E:240 I:275 55.0 0.216 S -54.6 -39.6 NA NA NA
TRP F:240 J:275 53.0 0.208 S -55.0 -39.8 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TRP A:240 A:275 71.0 0.278 S -54.6 -48.7 71.0 0.278 0.0 HOH
 2.986
 NE1
 O
TRP B:240 B:275 66.0 0.259 S -52.9 -52.4 NA NA NA
TRP C:240 C:275 59.0 0.231 S -56.9 -46.9 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TRP A:240 B:275 67.0 0.263 S -54.4 -40.7 67.0 0.263 0.0 HOH
 4.281
 CZ2
 O
TRP B:240 A:275 66.0 0.259 S -55.4 -41.4 NA NA NA
TRP C:240 C:275 66.0 0.259 S -53.5 -40.7 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TRP A:238 A:275 59.0 0.231 S -60.4 -39.5 59.0 0.231 0.0 HOH
 4.184
 O
 O
TRP B:238 B:275 59.0 0.231 S -60.1 -39.1 59.0 0.231 0.0 HOH
 1.785
 H
 O
TRP C:238 C:275 57.0 0.224 S -60.6 -39.1 57.0 0.224 0.0 HOH
 4.008
 CB
 O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TRP A:238 A:275 67.0 0.263 S -61.0 -39.5 67.0 0.263 0.0 HOH
 4.003
 O
 O
TRP B:238 B:275 67.0 0.263 S -60.1 -38.6 67.0 0.263 0.0 HOH
 4.062
 O
 O
TRP C:238 C:275 66.0 0.259 S -60.7 -38.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 TRP A:275 A:275 68.0 0.267 S -56.7 -47.3