Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 126092404 | . | T | A | CCDS7639.1:NM_000274.3:c.734tAc>tTc_NP_000265.1:p.245Y>F | Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-04-01 | TYR | A:245 | A:245 | 5.0 | 0.022 | H | -56.9 | -49.5 | 5.0 | 0.022 | 0.0 |
HOH |
2.731 |
OH |
O |
||
| TYR | B:245 | B:245 | 4.0 | 0.017 | H | -57.4 | -47.2 | 4.0 | 0.017 | 0.0 |
HOH |
2.477 |
OH |
O |
|||||||||
| TYR | C:245 | C:245 | 4.0 | 0.017 | H | -55.5 | -50.4 | NA | NA | NA | |||||||||||||
| 2oat | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-12-09 | TYR | A:245 | A:245 | 4.0 | 0.017 | H | -58.6 | -49.5 | NA | NA | NA | ||||||
| TYR | B:245 | B:245 | 3.0 | 0.013 | H | -60.6 | -46.8 | NA | NA | NA | |||||||||||||
| TYR | C:245 | C:245 | 4.0 | 0.017 | H | -56.7 | -52.0 | 4.0 | 0.017 | 0.0 |
HOH |
2.668 |
OH |
O |
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| 2byj | 1 | P04181 | 99.77 | 0.0 |
X-RAY |
2005-09-07 | TYR | A:245 | A:245 | 3.0 | 0.013 | H | -65.8 | -50.0 | 3.0 | 0.013 | 0.0 |
HOH |
2.614 |
OH |
O |
||
| TYR | B:245 | B:245 | 2.0 | 0.009 | H | -64.9 | -50.6 | 2.0 | 0.009 | 0.0 |
HOH |
7.719 |
CD2 |
O |
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| TYR | C:245 | C:245 | 3.0 | 0.013 | H | -66.6 | -50.4 | NA | NA | NA | |||||||||||||
| 2byl | 1 | P04181 | 99.32 | 0.0 |
X-RAY |
2005-09-07 | TYR | A:245 | A:245 | 6.0 | 0.026 | H | -63.1 | -46.3 | 6.0 | 0.026 | 0.0 |
HOH |
2.642 |
OH |
O |
||
| TYR | B:245 | B:245 | 5.0 | 0.022 | H | -55.2 | -47.9 | 5.0 | 0.022 | 0.0 |
HOH |
2.643 |
OH |
O |
|||||||||
| TYR | C:245 | C:245 | 5.0 | 0.022 | H | -57.9 | -50.1 | NA | NA | NA | |||||||||||||
| 6hx7 | 1 | P04181 | 99.76 | 0.0 |
X-RAY |
2019-06-05 | TYR | A:221 | A:245 | 4.0 | 0.017 | H | -62.4 | -52.1 | 4.0 | 0.017 | 0.0 |
HOH |
2.847 |
OH |
O |
||
| TYR | B:221 | B:245 | 4.0 | 0.017 | H | -61.7 | -50.3 | NA | NA | NA | |||||||||||||
| TYR | C:221 | C:245 | 4.0 | 0.017 | H | -60.6 | -52.7 | NA | NA | NA | |||||||||||||
| 5vwo | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2017-08-30 | TYR | A:210 | A:245 | 5.0 | 0.022 | H | -58.5 | -50.2 | 5.0 | 0.022 | 0.0 |
HOH |
2.683 |
OH |
O |
||
| TYR | B:210 | B:245 | 3.0 | 0.013 | H | -57.4 | -51.1 | 3.0 | 0.013 | 0.0 |
HOH |
2.604 |
OH |
O |
|||||||||
| TYR | C:210 | C:245 | 4.0 | 0.017 | H | -58.1 | -52.1 | 4.0 | 0.017 | 0.0 |
HOH |
2.640 |
OH |
O |
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| 6oia | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | TYR | A:210 | A:245 | 4.0 | 0.017 | H | -63.4 | -49.5 | 4.0 | 0.017 | 0.0 |
HOH |
2.744 |
OH |
O |
||
| TYR | B:210 | B:245 | 5.0 | 0.022 | H | -63.1 | -47.9 | 5.0 | 0.022 | 0.0 |
HOH |
2.752 |
OH |
O |
|||||||||
| TYR | C:210 | C:245 | 6.0 | 0.026 | H | -61.6 | -48.2 | NA | NA | NA | |||||||||||||
| 6v8c | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | TYR | A:210 | A:245 | 5.0 | 0.022 | H | -62.6 | -48.8 | 5.0 | 0.022 | 0.0 |
HOH |
2.881 |
OH |
O |
||
| TYR | B:210 | B:245 | 4.0 | 0.017 | H | -66.1 | -49.4 | NA | NA | NA | |||||||||||||
| TYR | C:210 | C:245 | 4.0 | 0.017 | H | -62.4 | -50.3 | NA | NA | NA | |||||||||||||
| 6v8d | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2020-12-16 | TYR | A:210 | A:245 | 4.0 | 0.017 | H | -61.4 | -49.2 | 4.0 | 0.017 | 0.0 |
HOH |
2.667 |
OH |
O |
||
| TYR | B:210 | B:245 | 4.0 | 0.017 | H | -59.4 | -48.4 | 4.0 | 0.017 | 0.0 |
HOH |
2.626 |
OH |
O |
|||||||||
| TYR | C:210 | C:245 | 3.0 | 0.013 | H | -60.4 | -53.2 | NA | NA | NA | |||||||||||||
| 7jx9 | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-01-06 | TYR | A:210 | A:245 | 4.0 | 0.017 | H | -57.1 | -51.1 | 4.0 | 0.017 | 0.0 |
HOH |
2.615 |
OH |
O |
||
| TYR | B:210 | B:245 | 5.0 | 0.022 | H | -56.8 | -50.6 | NA | NA | NA | |||||||||||||
| TYR | C:210 | C:245 | 4.0 | 0.017 | H | -60.7 | -54.2 | NA | NA | NA | |||||||||||||
| 7lnm | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TYR | A:210 | B:245 | 5.0 | 0.022 | H | -63.2 | -45.6 | 5.0 | 0.022 | 0.0 |
HOH |
2.770 |
OH |
O |
||
| TYR | B:210 | C:245 | 5.0 | 0.022 | H | -66.7 | -48.3 | 5.0 | 0.022 | 0.0 |
HOH |
2.711 |
OH |
O |
|||||||||
| TYR | C:210 | E:245 | 4.0 | 0.017 | H | -62.2 | -48.1 | NA | NA | NA | |||||||||||||
| TYR | D:210 | F:245 | 6.0 | 0.026 | H | -61.8 | -48.4 | NA | NA | NA | |||||||||||||
| TYR | E:210 | I:245 | 4.0 | 0.017 | H | -61.6 | -48.1 | NA | NA | NA | |||||||||||||
| TYR | F:210 | J:245 | 4.0 | 0.017 | H | -61.0 | -48.3 | NA | NA | NA | |||||||||||||
| 7lom | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TYR | A:210 | A:245 | 4.0 | 0.017 | H | -66.9 | -41.1 | 4.0 | 0.017 | 0.0 |
HOH |
2.896 |
OH |
O |
||
| TYR | B:210 | B:245 | 4.0 | 0.017 | H | -66.6 | -43.9 | NA | NA | NA | |||||||||||||
| TYR | C:210 | C:245 | 5.0 | 0.022 | H | -63.6 | -40.1 | NA | NA | NA | |||||||||||||
| 7lon | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
2021-08-25 | TYR | A:210 | B:245 | 5.0 | 0.022 | H | -62.2 | -47.0 | 5.0 | 0.022 | 0.0 |
HOH |
2.626 |
OH |
O |
||
| TYR | B:210 | A:245 | 4.0 | 0.017 | H | -59.3 | -44.9 | NA | NA | NA | |||||||||||||
| TYR | C:210 | C:245 | 4.0 | 0.017 | H | -60.3 | -46.6 | NA | NA | NA | |||||||||||||
| 1gbn | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | TYR | A:208 | A:245 | 2.0 | 0.009 | H | -57.2 | -53.4 | 2.0 | 0.009 | 0.0 |
HOH |
3.055 |
OH |
O |
||
| TYR | B:208 | B:245 | 2.0 | 0.009 | H | -56.8 | -53.3 | 2.0 | 0.009 | 0.0 |
HOH |
2.630 |
OH |
O |
|||||||||
| TYR | C:208 | C:245 | 2.0 | 0.009 | H | -57.0 | -52.9 | 2.0 | 0.009 | 0.0 |
HOH |
2.724 |
OH |
O |
|||||||||
| 2can | 1 | P04181 | 100.0 | 0.0 |
X-RAY |
1998-06-03 | TYR | A:208 | A:245 | 2.0 | 0.009 | H | -61.6 | -53.8 | 2.0 | 0.009 | 0.0 |
HOH |
3.891 |
CD1 |
O |
||
| TYR | B:208 | B:245 | 2.0 | 0.009 | H | -61.0 | -53.9 | 2.0 | 0.009 | 0.0 |
HOH |
1.885 |
HH |
O |
|||||||||
| TYR | C:208 | C:245 | 2.0 | 0.009 | H | -61.6 | -54.6 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04181-f1 | 1 | P04181 | 100.0 | 0.0 | TYR | A:245 | A:245 | 5.0 | 0.022 | H | -58.2 | -49.8 | |