Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126094075 . C A CCDS7639.1:NM_000274.3:c.578aGt>aTt_NP_000265.1:p.193S>I Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 SER A:193 A:193 9.0 0.078 H -80.6 -34.9 6.0 0.052 0.026 B:P04181:0.026
 HOH
 2.758
 O
 O
SER B:193 B:193 9.0 0.078 H -82.9 -32.0 5.0 0.043 0.035 A:P04181:0.035
 HOH
 2.725
 O
 O
SER C:193 C:193 9.0 0.078 H -78.3 -33.8 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 SER A:193 A:193 3.0 0.026 H -78.7 -42.7 NA NA NA
SER B:193 B:193 3.0 0.026 H -78.2 -45.9 NA NA NA
SER C:193 C:193 4.0 0.035 H -75.2 -42.0 4.0 0.035 0.0 PFM
PFM
HOH
 7.926
7.926
2.494
 OG
OG
OG
 OB
OB
O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 SER A:193 A:193 3.0 0.026 H -74.9 -42.0 2.0 0.017 0.009 B:P04181:0.009
 HOH
 3.558
 OG
 O
SER B:193 B:193 3.0 0.026 H -74.4 -41.5 2.0 0.017 0.009 A:P04181:0.009
 HOH
 3.330
 OG
 O
SER C:193 C:193 2.0 0.017 H -76.0 -41.0 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 SER A:193 A:193 4.0 0.035 H -76.7 -37.9 0.0 0.0 0.035 B:P04181:0.035
 HOH
 2.728
 O
 O
SER B:193 B:193 9.0 0.078 H -80.0 -31.3 5.0 0.043 0.035 A:P04181:0.035
 HOH
 2.595
 O
 O
SER C:193 C:193 3.0 0.026 H -76.2 -38.4 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 SER A:169 A:193 27.0 0.235 H -80.9 -42.4 16.0 0.139 0.096 A:P04181:0.096
 HOH
 2.585
 O
 O
SER B:169 B:193 30.0 0.261 H -75.0 -44.0 NA NA NA
SER C:169 C:193 24.0 0.209 H -87.7 -41.5 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 SER A:158 A:193 3.0 0.026 H -76.9 -39.0 3.0 0.026 0.0 9QJ
HOH
 5.461
2.569
 OG
OG
 O2F
O
SER B:158 B:193 3.0 0.026 H -75.2 -39.9 2.0 0.017 0.009 A:P04181:0.009
 9QJ
HOH
 5.444
2.635
 OG
O
 O1F
O
SER C:158 C:193 4.0 0.035 H -80.4 -37.1 4.0 0.035 0.0 9QJ
HOH
 5.289
2.647
 OG
O
 O2F
O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 SER A:158 A:193 5.0 0.043 H -75.9 -39.3 4.0 0.035 0.008 B:P04181:0.009
 HOH
 2.735
 O
 O
SER B:158 B:193 5.0 0.043 H -76.3 -41.3 4.0 0.035 0.008 A:P04181:0.009
 MQ4
HOH
 8.756
2.599
 OG
OG
 O11
O
SER C:158 C:193 3.0 0.026 H -78.5 -40.8 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 SER A:158 A:193 3.0 0.026 H -79.2 -41.9 2.0 0.017 0.009 A:P04181:0.009
 QRM
HOH
 9.550
2.651
 OG
O
 O9
O
SER B:158 B:193 4.0 0.035 H -77.2 -40.9 NA NA NA
SER C:158 C:193 3.0 0.026 H -78.9 -41.4 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 SER A:158 A:193 3.0 0.026 H -82.2 -35.8 1.0 0.009 0.017 B:P04181:0.017
 O78
HOH
 7.977
2.844
 OG
O
 C7
O
SER B:158 B:193 2.0 0.017 H -82.0 -36.2 2.0 0.017 0.0 O78
HOH
 8.054
3.853
 OG
OG
 C7
O
SER C:158 C:193 9.0 0.078 H -84.2 -35.1 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 SER A:158 A:193 2.0 0.017 H -76.4 -42.4 1.0 0.009 0.008 A:P04181:0.009
 IF1
HOH
 8.143
2.609
 OG
O
 F29
O
SER B:158 B:193 3.0 0.026 H -78.3 -41.3 NA NA NA
SER C:158 C:193 4.0 0.035 H -75.3 -44.5 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 SER A:158 B:193 2.0 0.017 H -75.8 -44.5 1.0 0.009 0.008 B:P04181:0.009
 Y7S
HOH
 8.770
2.586
 OG
O
 O19
O
SER B:158 C:193 4.0 0.035 H -79.7 -41.3 2.0 0.017 0.018 A:P04181:0.017
 Y7S
HOH
 9.020
2.607
 OG
O
 O20
O
SER C:158 E:193 3.0 0.026 H -75.9 -44.9 NA NA NA
SER D:158 F:193 2.0 0.017 H -76.4 -42.5 NA NA NA
SER E:158 I:193 3.0 0.026 H -79.4 -42.7 NA NA NA
SER F:158 J:193 2.0 0.017 H -79.3 -43.1 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 SER A:158 A:193 2.0 0.017 H -84.4 -39.6 2.0 0.017 0.0 HOH
 2.618
 OG
 O
SER B:158 B:193 4.0 0.035 H -93.8 -31.6 NA NA NA
SER C:158 C:193 3.0 0.026 H -77.4 -44.3 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 SER A:158 B:193 5.0 0.043 H -78.6 -33.9 3.0 0.026 0.017 A:P04181:0.017
 7QP
HOH
 8.890
2.561
 CB
O
 O05
O
SER B:158 A:193 4.0 0.035 H -78.7 -40.8 NA NA NA
SER C:158 C:193 4.0 0.035 H -77.4 -41.0 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 SER A:156 A:193 2.0 0.017 H -88.5 -39.8 2.0 0.017 0.0 GAB
PLP
HOH
 9.431
9.815
2.443
 HG
HG
HG
 O1'
C4A
O
SER B:156 B:193 3.0 0.026 H -89.4 -38.3 2.0 0.017 0.009 A:P04181:0.009
 GBC
PLP
HOH
 9.489
9.894
2.412
 HG
HG
HG
 O2
C4A
O
SER C:156 C:193 2.0 0.017 H -89.5 -39.5 2.0 0.017 0.0 GBC
PLP
HOH
 9.457
9.830
2.610
 HG
HG
OG
 O1
C4A
O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 SER A:156 A:193 3.0 0.026 H -94.3 -26.5 2.0 0.017 0.009 B:P04181:0.009
 CAN
HOH
 8.227
2.625
 CB
O
 OXT
O
SER B:156 B:193 4.0 0.035 H -93.7 -26.6 2.0 0.017 0.018 A:P04181:0.017
 CAN
HOH
 8.272
2.825
 CB
O
 O
O
SER C:156 C:193 3.0 0.026 H -94.3 -26.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 SER A:193 A:193 6.0 0.052 H -85.7 -34.6