Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126094114 . C A CCDS7639.1:NM_000274.3:c.539aGg>aTg_NP_000265.1:p.180R>M Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 ARG A:180 A:180 140.0 0.622 S -120.7 13.0 37.0 0.164 0.458 B:P04181:0.458
 PLP
HOH
 5.787
3.636
 N
NE
 O2P
O
ARG B:180 B:180 142.0 0.631 S -120.6 14.4 39.0 0.173 0.458 A:P04181:0.458
 PLP
HOH
 5.739
3.440
 N
NE
 O2P
O
ARG C:180 C:180 141.0 0.627 S -120.6 16.7 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 ARG A:180 A:180 146.0 0.649 S -125.3 19.9 NA NA NA
ARG B:180 B:180 149.0 0.662 S -124.8 10.3 NA NA NA
ARG C:180 C:180 145.0 0.644 S -121.7 8.5 145.0 0.644 0.0 PFM
PFM
HOH
 3.345
3.345
2.843
 NH2
NH2
N
 OB
OB
O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 ARG A:180 A:180 142.0 0.631 S -132.5 10.7 36.0 0.16 0.471 B:P04181:0.471
 PLP
HOH
 5.575
3.058
 N
NE
 O2P
O
ARG B:180 B:180 144.0 0.64 S -130.9 10.8 34.0 0.151 0.489 A:P04181:0.489
 PLP
HOH
 5.650
6.190
 N
NH1
 O2P
O
ARG C:180 C:180 140.0 0.622 S -132.8 10.1 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 ARG A:180 A:180 118.0 0.524 -132.9 21.0 19.0 0.084 0.44 B:P04181:0.44
 PLP
HOH
 5.824
2.961
 N
NH1
 O2P
O
ARG B:180 B:180 165.0 0.733 S -132.8 22.2 31.0 0.138 0.595 A:P04181:0.596
 PLP
HOH
 5.798
2.615
 N
NH2
 O2P
O
ARG C:180 C:180 128.0 0.569 S -128.9 18.6 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 THR A:156 A:180 116.0 0.829 S -129.8 4.7 12.0 0.086 0.743 A:P04181:0.743
 PLP
HOH
 5.744
2.925
 N
OG1
 O3P
O
THR B:156 B:180 114.0 0.814 S -128.7 9.6 NA NA NA
THR C:156 C:180 114.0 0.814 S -127.5 6.7 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 ARG A:145 A:180 157.0 0.698 -124.4 19.1 51.0 0.227 0.471 B:P04181:0.471
 9QJ
HOH
 2.941
2.850
 NE
N
 O1F
O
ARG B:145 B:180 159.0 0.707 -126.5 17.9 54.0 0.24 0.467 A:P04181:0.467
 9QJ
HOH
 2.894
2.930
 NE
N
 O2F
O
ARG C:145 C:180 159.0 0.707 -128.9 19.0 159.0 0.707 0.0 9QJ
HOH
 2.747
2.922
 NE
N
 O1F
O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 ARG A:145 A:180 143.0 0.636 S -128.3 9.1 34.0 0.151 0.485 B:P04181:0.484
 PLP
HOH
 5.799
3.016
 N
NH2
 O2P
O
ARG B:145 B:180 146.0 0.649 S -126.1 9.7 38.0 0.169 0.48 A:P04181:0.48
 PLP
MQ4
HOH
 5.666
4.548
2.826
 N
NH2
NH2
 O2P
O11
O
ARG C:145 C:180 150.0 0.667 S -128.4 8.8 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 ARG A:145 A:180 144.0 0.64 S -128.2 6.4 34.0 0.151 0.489 A:P04181:0.489
 PLP
QRM
HOH
 5.615
4.908
2.760
 N
NE
NE
 O3P
O9
O
ARG B:145 B:180 141.0 0.627 S -128.5 8.0 NA NA NA
ARG C:145 C:180 144.0 0.64 S -127.5 6.0 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 ARG A:145 A:180 149.0 0.662 -127.1 20.2 39.0 0.173 0.489 B:P04181:0.489
 PLP
O78
HOH
 5.797
3.351
3.181
 N
NH1
N
 O1P
O8
O
ARG B:145 B:180 134.0 0.596 -132.3 23.8 31.0 0.138 0.458 A:P04181:0.458
 PLP
O78
HOH
 5.892
3.849
3.322
 N
CG
N
 O3P
O9
O
ARG C:145 C:180 158.0 0.702 -145.0 27.6 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 ARG A:145 A:180 148.0 0.658 S -125.8 9.6 36.0 0.16 0.498 A:P04181:0.498
 IF1
HOH
 4.576
2.844
 NH1
NE
 O26
O
ARG B:145 B:180 150.0 0.667 S -125.5 7.3 NA NA NA
ARG C:145 C:180 150.0 0.667 S -118.6 4.7 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 ARG A:145 B:180 142.0 0.631 S -123.8 7.9 31.0 0.138 0.493 B:P04181:0.493
 Y7S
HOH
 4.549
2.587
 NH2
NH2
 O19
O
ARG B:145 C:180 152.0 0.676 S -124.4 5.5 39.0 0.173 0.503 A:P04181:0.502
 Y7S
HOH
 5.822
2.927
 N
N
 O42
O
ARG C:145 E:180 146.0 0.649 S -124.8 8.8 NA NA NA
ARG D:145 F:180 144.0 0.64 -133.0 20.5 NA NA NA
ARG E:145 I:180 139.0 0.618 S -126.2 12.7 NA NA NA
ARG F:145 J:180 141.0 0.627 S -124.9 12.1 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 ARG A:145 A:180 139.0 0.618 S -128.7 16.0 31.0 0.138 0.48 A:P04181:0.48
 THR
Y8P
HOH
 7.327
5.805
3.089
 CG
N
NH2
 N
O44
O
ARG B:145 B:180 143.0 0.636 S -126.1 10.8 NA NA NA
ARG C:145 C:180 139.0 0.618 S -123.6 10.2 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 ARG A:145 B:180 141.0 0.627 -133.1 15.2 32.0 0.142 0.485 A:P04181:0.484
 THR
7QP
HOH
 7.838
3.740
2.763
 CD
NE
N
 N
O05
O
ARG B:145 A:180 134.0 0.596 S -128.4 5.2 NA NA NA
ARG C:145 C:180 144.0 0.64 -133.0 9.7 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 ARG A:143 A:180 145.0 0.644 S -124.7 15.7 33.0 0.147 0.497 B:P04181:0.498
 GAB
PLP
HOH
 3.681
4.902
2.181
 HE
H
HH12
 O1'
O1P
O
ARG B:143 B:180 147.0 0.653 S -124.1 16.1 34.0 0.151 0.502 A:P04181:0.502
 GBC
PLP
HOH
 3.775
5.069
2.292
 HE
H
HH11
 O2
O1P
O
ARG C:143 C:180 148.0 0.658 S -125.0 15.8 148.0 0.658 0.0 GBC
PLP
HOH
 3.813
4.827
1.828
 HE
H
HE
 O1
O1P
O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 ARG A:143 A:180 123.0 0.547 S -124.6 12.1 24.0 0.107 0.44 B:P04181:0.378
 CAN
PLP
HOH
 2.343
5.086
2.466
 HE
H
HH11
 OXT
O1P
O
ARG B:143 B:180 127.0 0.564 S -124.3 11.1 23.0 0.102 0.462 A:P04181:0.396
 CAN
PLP
HOH
 2.465
5.023
2.129
 HE
H
HH11
 O
O1P
O
ARG C:143 C:180 129.0 0.573 S -124.1 11.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 ARG A:180 A:180 146.0 0.649 S -135.6 14.3