Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126094119 . C A CCDS7639.1:NM_000274.3:c.534tgG>tgT_NP_000265.1:p.178W>C Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 TRP A:178 A:178 11.0 0.043 -135.6 13.9 11.0 0.043 0.0 PLP
HOH
 3.500
3.514
 CA
CD1
 C6
O
TRP B:178 B:178 11.0 0.043 -140.0 17.5 11.0 0.043 0.0 PLP
HOH
 3.462
3.361
 CA
N
 C6
O
TRP C:178 C:178 12.0 0.047 -140.0 15.9 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 TRP A:178 A:178 12.0 0.047 -136.7 19.8 NA NA NA
TRP B:178 B:178 10.0 0.039 -127.3 20.2 NA NA NA
TRP C:178 C:178 12.0 0.047 -140.4 18.4 12.0 0.047 0.0 PFM
PFM
HOH
 3.439
3.439
3.422
 CA
CA
CD1
 C6
C6
O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 TRP A:178 A:178 10.0 0.039 -133.4 34.2 10.0 0.039 0.0 PLP
HOH
 3.367
5.861
 CA
N
 C6
O
TRP B:178 B:178 10.0 0.039 -133.7 33.2 10.0 0.039 0.0 PLP
HOH
 3.378
5.531
 CA
N
 C6
O
TRP C:178 C:178 9.0 0.035 -132.9 33.2 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 TRP A:178 A:178 11.0 0.043 -144.3 22.7 11.0 0.043 0.0 PLP
HOH
 3.307
2.819
 CA
N
 C6
O
TRP B:178 B:178 10.0 0.039 -141.1 20.4 10.0 0.039 0.0 PLP
HOH
 3.361
2.865
 CA
N
 C6
O
TRP C:178 C:178 9.0 0.035 -142.4 21.1 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 TRP A:154 A:178 12.0 0.047 -138.3 23.5 12.0 0.047 0.0 PLP
HOH
 3.220
2.958
 CA
N
 C6
O
TRP B:154 B:178 11.0 0.043 -141.9 19.4 NA NA NA
TRP C:154 C:178 11.0 0.043 -139.1 23.0 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 TRP A:143 A:178 18.0 0.071 -138.5 25.9 18.0 0.071 0.0 9QJ
HOH
 3.310
2.891
 CA
N
 C6
O
TRP B:143 B:178 16.0 0.063 -139.4 24.4 16.0 0.063 0.0 9QJ
HOH
 3.299
2.731
 CA
N
 C6
O
TRP C:143 C:178 16.0 0.063 -138.6 25.0 16.0 0.063 0.0 9QJ
HOH
 3.311
2.699
 CA
N
 C6
O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 TRP A:143 A:178 12.0 0.047 -142.6 22.2 12.0 0.047 0.0 PLP
HOH
 3.321
2.739
 CA
N
 C6
O
TRP B:143 B:178 11.0 0.043 -134.8 23.6 11.0 0.043 0.0 PLP
MQ4
HOH
 3.359
5.900
2.746
 CA
C
N
 C6
N10
O
TRP C:143 C:178 13.0 0.051 -140.1 18.8 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TRP A:143 A:178 12.0 0.047 -136.9 21.3 11.0 0.043 0.004 A:P04181:0.004
 PLP
QRM
HOH
 3.343
6.359
2.749
 CA
C
N
 C6
N10
O
TRP B:143 B:178 12.0 0.047 -137.8 21.0 NA NA NA
TRP C:143 C:178 12.0 0.047 -138.1 22.9 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TRP A:143 A:178 16.0 0.063 -145.8 26.1 16.0 0.063 0.0 PLP
O78
HOH
 3.315
3.796
2.905
 CA
N
N
 C6
N10
O
TRP B:143 B:178 16.0 0.063 -137.9 23.6 16.0 0.063 0.0 PLP
O78
HOH
 3.341
3.794
2.691
 CA
N
N
 C6
N10
O
TRP C:143 C:178 16.0 0.063 -142.6 22.4 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 TRP A:143 A:178 14.0 0.055 -130.6 21.5 14.0 0.055 0.0 IF1
VLS
HOH
 3.425
9.794
3.248
 O
CZ2
N
 C07
O07
O
TRP B:143 B:178 14.0 0.055 -134.0 22.5 NA NA NA
TRP C:143 C:178 12.0 0.047 -133.5 18.5 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TRP A:143 B:178 11.0 0.043 -136.0 20.5 11.0 0.043 0.0 Y7S
HOH
 3.354
2.603
 O
N
 C14
O
TRP B:143 C:178 14.0 0.055 -146.8 23.8 14.0 0.055 0.0 Y7S
HOH
 3.204
3.292
 O
CD1
 C14
O
TRP C:143 E:178 13.0 0.051 -134.5 22.2 NA NA NA
TRP D:143 F:178 14.0 0.055 -145.9 26.8 NA NA NA
TRP E:143 I:178 12.0 0.047 -136.9 21.0 NA NA NA
TRP F:143 J:178 13.0 0.051 -138.1 20.4 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TRP A:143 A:178 13.0 0.051 -139.4 26.7 13.0 0.051 0.0 THR
Y8P
HOH
 8.389
3.328
3.193
 C
CA
N
 OG1
C15
O
TRP B:143 B:178 15.0 0.059 -147.2 28.6 NA NA NA
TRP C:143 C:178 14.0 0.055 -142.5 28.5 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TRP A:143 B:178 13.0 0.051 -141.9 20.6 13.0 0.051 0.0 THR
7QP
HOH
 8.780
3.306
2.616
 O
CA
N
 OG1
C15
O
TRP B:143 A:178 13.0 0.051 -140.5 23.1 NA NA NA
TRP C:143 C:178 11.0 0.043 -141.8 23.3 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TRP A:141 A:178 14.0 0.055 -134.3 19.2 14.0 0.055 0.0 GAB
PLP
HOH
 6.495
3.491
2.356
 C
O
H
 N3
C6
O
TRP B:141 B:178 14.0 0.055 -134.3 18.7 14.0 0.055 0.0 GBC
PLP
HOH
 6.367
3.423
2.350
 C
O
H
 N3
C5A
O
TRP C:141 C:178 15.0 0.059 -134.5 19.0 15.0 0.059 0.0 GBC
PLP
HOH
 6.274
3.392
2.231
 C
O
H
 N3
C6
O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TRP A:141 A:178 13.0 0.051 -137.2 21.4 13.0 0.051 0.0 CAN
PLP
HOH
 5.953
3.531
2.951
 C
CA
H
 NZ
C6
O
TRP B:141 B:178 14.0 0.055 -137.0 20.0 13.0 0.051 0.004 A:P04181:0.004
 CAN
PLP
HOH
 6.489
3.446
2.632
 C
CA
H
 NZ
C6
O
TRP C:141 C:178 13.0 0.051 -136.9 19.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 TRP A:178 A:178 12.0 0.047 -131.6 8.4