Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126097133 . G A CCDS7639.1:NM_000274.3:c.498taC>taT_NP_000265.1:p.166Y>Y Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 TYR A:166 A:166 180.0 0.783 T 79.7 29.1 66.0 0.287 0.496 B:P04181:0.496
 HOH
 2.706
 OH
 O
TYR B:166 B:166 178.0 0.774 T 83.6 26.5 67.0 0.291 0.483 A:P04181:0.483
 HOH
 2.522
 OH
 O
TYR C:166 C:166 180.0 0.783 T 76.2 32.2 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 TYR A:166 A:166 176.0 0.765 T -119.4 70.1 NA NA NA
TYR B:166 B:166 173.0 0.752 T -121.2 64.1 NA NA NA
TYR C:166 C:166 179.0 0.778 T -119.1 68.2 179.0 0.778 0.0 HOH
 2.653
 OH
 O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 TYR A:166 A:166 176.0 0.765 T -120.9 75.2 67.0 0.291 0.474 B:P04181:0.474
 HOH
 6.804
 O
 O
TYR B:166 B:166 179.0 0.778 T -119.4 75.4 71.0 0.309 0.469 A:P04181:0.47
 HOH
 2.713
 N
 O
TYR C:166 C:166 179.0 0.778 T -121.3 74.3 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 TYR A:166 A:166 171.0 0.743 T -121.8 68.1 61.0 0.265 0.478 B:P04181:0.478
 HOH
 2.672
 OH
 O
TYR B:166 B:166 192.0 0.835 T -120.2 67.5 77.0 0.335 0.5 A:P04181:0.5
 HOH
 2.482
 OH
 O
TYR C:166 C:166 180.0 0.783 T -126.9 69.6 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 TYR A:142 A:166 178.0 0.774 T -117.0 65.5 69.0 0.3 0.474 A:P04181:0.474
 HOH
 2.582
 OH
 O
TYR B:142 B:166 179.0 0.778 T -117.4 67.6 NA NA NA
TYR C:142 C:166 175.0 0.761 T -117.5 65.1 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 TYR A:131 A:166 172.0 0.748 T -119.7 71.4 5.0 0.022 0.726 C:P04181:0.317
B:P04181:0.483
 HOH
 2.737
 OH
 O
TYR B:131 B:166 170.0 0.739 T -116.9 74.9 59.0 0.257 0.482 A:P04181:0.483
 HOH
 2.563
 OH
 O
TYR C:131 C:166 173.0 0.752 T -121.1 71.2 173.0 0.752 0.0 HOH
 2.563
 OH
 O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 TYR A:131 A:166 174.0 0.757 T -123.2 70.0 61.0 0.265 0.492 B:P04181:0.491
 GOL
HOH
 3.000
2.585
 O
OH
 O2
O
TYR B:131 B:166 179.0 0.778 T -115.5 66.4 66.0 0.287 0.491 A:P04181:0.491
 HOH
 2.428
 OH
 O
TYR C:131 C:166 180.0 0.783 T -120.2 68.4 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:131 A:166 176.0 0.765 T -124.4 70.2 65.0 0.283 0.482 A:P04181:0.483
 HOH
 2.541
 OH
 O
TYR B:131 B:166 180.0 0.783 T -121.7 69.5 NA NA NA
TYR C:131 C:166 176.0 0.765 T -123.8 70.2 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:131 A:166 178.0 0.774 T 82.2 19.0 68.0 0.296 0.478 B:P04181:0.478
 HOH
 2.575
 OH
 O
TYR B:131 B:166 180.0 0.783 T 82.2 16.8 66.0 0.287 0.496 A:P04181:0.496
 HOH
 2.496
 OH
 O
TYR C:131 C:166 181.0 0.787 T 81.1 19.2 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 TYR A:131 A:166 175.0 0.761 T -174.1 43.0 64.0 0.278 0.483 A:P04181:0.483
 VLS
HOH
 8.756
2.635
 CE2
OH
 O05
O
TYR B:131 B:166 177.0 0.77 T 171.0 41.1 NA NA NA
TYR C:131 C:166 185.0 0.804 T 161.6 38.3 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:131 B:166 176.0 0.765 T -116.0 72.3 59.0 0.257 0.508 B:P04181:0.509
 HOH
 2.392
 OH
 O
TYR B:131 C:166 173.0 0.752 T -121.5 75.6 61.0 0.265 0.487 A:P04181:0.487
 HOH
 2.575
 OH
 O
TYR C:131 E:166 178.0 0.774 T -114.9 73.2 NA NA NA
TYR D:131 F:166 171.0 0.743 T -120.9 74.5 NA NA NA
TYR E:131 I:166 180.0 0.783 T -120.5 72.3 NA NA NA
TYR F:131 J:166 178.0 0.774 T -121.0 75.4 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:131 A:166 182.0 0.791 T 82.4 18.2 73.0 0.317 0.474 A:P04181:0.474
 HOH
 2.533
 OH
 O
TYR B:131 B:166 180.0 0.783 T 77.0 22.8 NA NA NA
TYR C:131 C:166 180.0 0.783 T 80.2 21.1 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:131 B:166 179.0 0.778 T 86.4 16.1 68.0 0.296 0.482 A:P04181:0.483
 HOH
 2.430
 OH
 O
TYR B:131 A:166 175.0 0.761 T 86.6 14.3 NA NA NA
TYR C:131 C:166 177.0 0.77 T 87.9 14.6 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:129 A:166 176.0 0.765 T 72.8 24.0 12.0 0.052 0.713 C:P04181:0.304
B:P04181:0.474
 HOH
 2.498
 HH
 O
TYR B:129 B:166 177.0 0.77 T 72.4 23.2 65.0 0.283 0.487 A:P04181:0.487
 HOH
 1.731
 HH
 O
TYR C:129 C:166 179.0 0.778 T 73.7 23.2 179.0 0.778 0.0 HOH
 2.236
 HH
 O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:129 A:166 179.0 0.778 T 74.6 22.0 67.0 0.291 0.487 B:P04181:0.487
 HOH
 1.857
 HH
 O
TYR B:129 B:166 184.0 0.8 T 73.7 23.0 70.0 0.304 0.496 A:P04181:0.496
 HOH
 1.650
 HH
 O
TYR C:129 C:166 179.0 0.778 T 74.0 22.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 TYR A:166 A:166 186.0 0.809 T 64.4 16.4