Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126097158 . T A CCDS7639.1:NM_000274.3:c.473tAt>tTt_NP_000265.1:p.158Y>F Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 TYR A:158 A:158 35.0 0.152 I -77.3 -44.2 18.0 0.078 0.074 B:P04181:0.074
 HOH
 3.080
 O
 O
TYR B:158 B:158 38.0 0.165 I -76.4 -42.4 19.0 0.083 0.082 A:P04181:0.083
 HOH
 3.453
 O
 O
TYR C:158 C:158 35.0 0.152 I -75.2 -45.1 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 TYR A:158 A:158 34.0 0.148 I -75.1 -50.6 NA NA NA
TYR B:158 B:158 35.0 0.152 I -82.5 -39.0 NA NA NA
TYR C:158 C:158 34.0 0.148 I -76.1 -49.1 34.0 0.148 0.0 HOH
 3.156
 O
 O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 TYR A:158 A:158 33.0 0.143 I -80.6 -54.6 16.0 0.07 0.073 B:P04181:0.074
 HOH
 5.910
 OH
 O
TYR B:158 B:158 34.0 0.148 I -81.8 -54.1 16.0 0.07 0.078 A:P04181:0.078
 HOH
 5.849
 OH
 O
TYR C:158 C:158 34.0 0.148 I -81.4 -54.4 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 TYR A:158 A:158 35.0 0.152 I -75.8 -47.4 17.0 0.074 0.078 B:P04181:0.078
 HOH
 3.757
 O
 O
TYR B:158 B:158 30.0 0.13 I -78.8 -41.1 11.0 0.048 0.082 A:P04181:0.083
 HOH
 2.751
 O
 O
TYR C:158 C:158 34.0 0.148 I -77.0 -44.2 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 TYR A:134 A:158 32.0 0.139 I -78.6 -45.9 18.0 0.078 0.061 A:P04181:0.061
 HOH
 2.930
 O
 O
TYR B:134 B:158 35.0 0.152 I -76.8 -45.2 NA NA NA
TYR C:134 C:158 37.0 0.161 H -76.9 -46.8 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 TYR A:123 A:158 33.0 0.143 I -79.1 -44.9 17.0 0.074 0.069 B:P04181:0.07
 HOH
 3.176
 O
 O
TYR B:123 B:158 32.0 0.139 I -83.8 -39.7 16.0 0.07 0.069 A:P04181:0.07
 HOH
 3.117
 O
 O
TYR C:123 C:158 34.0 0.148 I -76.0 -48.1 34.0 0.148 0.0 HOH
 3.083
 O
 O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 TYR A:123 A:158 35.0 0.152 I -76.8 -43.8 17.0 0.074 0.078 B:P04181:0.078
 GOL
HOH
 6.440
2.893
 OH
O
 O2
O
TYR B:123 B:158 29.0 0.126 I -82.2 -39.8 17.0 0.074 0.052 A:P04181:0.052
 HOH
 3.031
 O
 O
TYR C:123 C:158 34.0 0.148 I -75.0 -43.2 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:123 A:158 37.0 0.161 I -77.7 -41.9 19.0 0.083 0.078 A:P04181:0.078
 HOH
 2.862
 O
 O
TYR B:123 B:158 32.0 0.139 I -77.9 -43.4 NA NA NA
TYR C:123 C:158 39.0 0.17 I -78.0 -42.0 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:123 A:158 35.0 0.152 I -83.0 -46.7 17.0 0.074 0.078 B:P04181:0.078
 HOH
 3.497
 O
 O
TYR B:123 B:158 34.0 0.148 I -81.3 -41.5 17.0 0.074 0.074 A:P04181:0.074
 HOH
 2.943
 O
 O
TYR C:123 C:158 33.0 0.143 I -78.7 -43.6 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 TYR A:123 A:158 35.0 0.152 I -78.3 -40.9 19.0 0.083 0.069 A:P04181:0.07
 HOH
 2.917
 O
 O
TYR B:123 B:158 33.0 0.143 I -84.0 -35.0 NA NA NA
TYR C:123 C:158 34.0 0.148 I -82.3 -39.0 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:123 B:158 26.0 0.113 I -78.8 -44.2 11.0 0.048 0.065 B:P04181:0.065
 HOH
 3.219
 O
 O
TYR B:123 C:158 33.0 0.143 I -77.3 -45.4 16.0 0.07 0.073 A:P04181:0.074
 HOH
 2.736
 O
 O
TYR C:123 E:158 34.0 0.148 I -79.6 -40.1 NA NA NA
TYR D:123 F:158 33.0 0.143 I -75.0 -46.7 NA NA NA
TYR E:123 I:158 33.0 0.143 I -75.1 -43.2 NA NA NA
TYR F:123 J:158 36.0 0.157 I -75.2 -41.6 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:123 A:158 33.0 0.143 I -79.2 -52.8 17.0 0.074 0.069 A:P04181:0.07
 HOH
 3.089
 O
 O
TYR B:123 B:158 33.0 0.143 I -78.5 -44.6 NA NA NA
TYR C:123 C:158 38.0 0.165 I -84.8 -47.3 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:123 B:158 35.0 0.152 I -70.1 -45.3 19.0 0.083 0.069 A:P04181:0.07
 HOH
 2.867
 O
 O
TYR B:123 A:158 38.0 0.165 I -69.3 -46.2 NA NA NA
TYR C:123 C:158 40.0 0.174 I -68.8 -45.9 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:121 A:158 34.0 0.148 I -81.6 -48.6 17.0 0.074 0.074 B:P04181:0.074
 HOH
 3.082
 O
 O
TYR B:121 B:158 33.0 0.143 I -81.5 -49.1 17.0 0.074 0.069 A:P04181:0.07
 HOH
 4.573
 HH
 O
TYR C:121 C:158 31.0 0.135 I -80.1 -50.0 31.0 0.135 0.0 HOH
 3.205
 O
 O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:121 A:158 34.0 0.148 I -78.9 -55.6 17.0 0.074 0.074 B:P04181:0.074
 HOH
 3.351
 O
 O
TYR B:121 B:158 35.0 0.152 I -78.4 -56.0 16.0 0.07 0.082 A:P04181:0.083
 HOH
 3.866
 O
 O
TYR C:121 C:158 34.0 0.148 I -78.2 -55.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 TYR A:158 A:158 44.0 0.191 H -77.1 -45.0