Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126097420 . A C CCDS7639.1:NM_000274.3:c.314gTg>gGg_NP_000265.1:p.105V>G Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 VAL A:105 A:105 69.0 0.445 H -54.0 -35.9 0.0 0.0 0.445 B:P04181:0.445
 HOH
 5.552
 O
 O
VAL B:105 B:105 66.0 0.426 H -52.4 -35.7 1.0 0.006 0.42 A:P04181:0.419
 HOH
 6.383
 O
 O
VAL C:105 C:105 68.0 0.439 H -54.9 -37.7 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 VAL A:105 A:105 66.0 0.426 H -65.2 -22.3 NA NA NA
VAL B:105 B:105 67.0 0.432 H -61.0 -23.4 NA NA NA
VAL C:105 C:105 71.0 0.458 H -65.2 -16.5 71.0 0.458 0.0 HOH
 5.452
 O
 O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 VAL A:105 A:105 69.0 0.445 H -68.6 -31.1 0.0 0.0 0.445 B:P04181:0.445
VAL B:105 B:105 72.0 0.465 H -68.2 -30.9 0.0 0.0 0.465 A:P04181:0.465
 HOH
 7.748
 N
 O
VAL C:105 C:105 70.0 0.452 H -68.7 -30.5 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 VAL A:105 A:105 75.0 0.484 H -60.7 -24.1 1.0 0.006 0.478 B:P04181:0.477
 HOH
 5.103
 O
 O
VAL B:105 B:105 72.0 0.465 H -59.3 -26.7 0.0 0.0 0.465 A:P04181:0.465
 HOH
 6.178
 N
 O
VAL C:105 C:105 74.0 0.477 H -57.3 -29.9 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 VAL A:81 A:105 70.0 0.452 H -64.0 -28.8 0.0 0.0 0.452 A:P04181:0.452
 HOH
 5.456
 CG1
 O
VAL B:81 B:105 73.0 0.471 H -64.2 -27.4 NA NA NA
VAL C:81 C:105 71.0 0.458 H -64.6 -27.9 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 VAL A:70 A:105 72.0 0.465 T -63.7 -20.4 1.0 0.006 0.459 B:P04181:0.458
 HOH
 5.410
 O
 O
VAL B:70 B:105 71.0 0.458 H -65.6 -19.0 0.0 0.0 0.458 A:P04181:0.458
 HOH
 5.613
 O
 O
VAL C:70 C:105 73.0 0.471 H -65.3 -23.5 73.0 0.471 0.0 HOH
 5.384
 CG1
 O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 VAL A:70 A:105 71.0 0.458 H -63.8 -23.2 0.0 0.0 0.458 B:P04181:0.458
 HOH
 5.347
 O
 O
VAL B:70 B:105 73.0 0.471 H -63.5 -23.5 0.0 0.0 0.471 A:P04181:0.471
 HOH
 5.434
 O
 O
VAL C:70 C:105 73.0 0.471 H -68.3 -22.1 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 VAL A:70 A:105 72.0 0.465 H -67.3 -20.2 0.0 0.0 0.465 A:P04181:0.465
 HOH
 5.968
 N
 O
VAL B:70 B:105 72.0 0.465 H -67.5 -20.8 NA NA NA
VAL C:70 C:105 72.0 0.465 H -68.3 -20.6 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 VAL A:70 A:105 68.0 0.439 H -63.5 -21.8 0.0 0.0 0.439 B:P04181:0.439
 HOH
 5.631
 O
 O
VAL B:70 B:105 73.0 0.471 H -61.8 -21.6 0.0 0.0 0.471 A:P04181:0.471
 HOH
 5.214
 O
 O
VAL C:70 C:105 73.0 0.471 H -83.9 -27.2 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 VAL A:70 A:105 75.0 0.484 H -73.1 -16.7 1.0 0.006 0.478 A:P04181:0.477
 HOH
 6.438
 O
 O
VAL B:70 B:105 67.0 0.432 H -63.4 -18.9 NA NA NA
VAL C:70 C:105 70.0 0.452 H -62.5 -22.8 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 VAL A:70 B:105 73.0 0.471 H -65.6 -19.2 0.0 0.0 0.471 B:P04181:0.471
 HOH
 5.274
 O
 O
VAL B:70 C:105 70.0 0.452 H -66.5 -22.3 0.0 0.0 0.452 A:P04181:0.452
 HOH
 5.210
 O
 O
VAL C:70 E:105 69.0 0.445 H -64.8 -19.2 NA NA NA
VAL D:70 F:105 63.0 0.406 H -61.6 -30.2 NA NA NA
VAL E:70 I:105 74.0 0.477 H -70.3 -18.4 NA NA NA
VAL F:70 J:105 73.0 0.471 H -68.8 -20.1 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 VAL A:70 A:105 69.0 0.445 H -67.0 -25.6 0.0 0.0 0.445 A:P04181:0.445
 HOH
 6.257
 N
 O
VAL B:70 B:105 71.0 0.458 H -65.9 -23.6 NA NA NA
VAL C:70 C:105 66.0 0.426 H -62.1 -21.5 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 VAL A:70 B:105 72.0 0.465 H -65.6 -23.7 0.0 0.0 0.465 A:P04181:0.465
 HOH
 5.809
 O
 O
VAL B:70 A:105 71.0 0.458 H -66.9 -23.5 NA NA NA
VAL C:70 C:105 71.0 0.458 H -66.1 -22.8 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 VAL A:68 A:105 62.0 0.4 H -58.3 -28.4 0.0 0.0 0.4 B:P04181:0.4
 HOH
 6.675
 O
 O
VAL B:68 B:105 62.0 0.4 H -58.9 -28.1 0.0 0.0 0.4 A:P04181:0.4
 HOH
 6.285
 O
 O
VAL C:68 C:105 62.0 0.4 H -58.4 -28.6 62.0 0.4 0.0 HOH
 7.180
 CG1
 O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 VAL A:68 A:105 62.0 0.4 T -59.7 -23.1 1.0 0.006 0.394 B:P04181:0.394
 HOH
 6.285
 H
 O
VAL B:68 B:105 63.0 0.406 T -58.9 -23.1 1.0 0.006 0.4 A:P04181:0.4
 HOH
 6.557
 O
 O
VAL C:68 C:105 63.0 0.406 T -59.6 -22.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 VAL A:105 A:105 67.0 0.432 H -63.9 -32.8