Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 126100578 . A C CCDS7639.1:NM_000274.3:c.163Tac>Gac_NP_000265.1:p.55Y>D Homo sapiens ornithine aminotransferase (OAT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1oat 1 P04181 100.0 0.0 X-RAY
 1998-04-01 TYR A:55 A:55 158.0 0.687 -132.3 153.2 42.0 0.183 0.504 B:P04181:0.504
 PLP
HOH
 7.045
2.576
 OH
OH
 O3P
O
TYR B:55 B:55 159.0 0.691 -132.6 152.5 41.0 0.178 0.513 A:P04181:0.513
 PLP
HOH
 6.973
2.721
 OH
OH
 O3P
O
TYR C:55 C:55 156.0 0.678 -130.4 153.8 NA NA NA
2oat 1 P04181 100.0 0.0 X-RAY
 1998-12-09 TYR A:55 A:55 172.0 0.748 -125.6 153.6 NA NA NA
TYR B:55 B:55 146.0 0.635 -123.6 151.5 NA NA NA
TYR C:55 C:55 172.0 0.748 -140.7 159.1 172.0 0.748 0.0 PFM
PFM
HOH
 2.540
2.540
2.823
 OH
OH
O
 N
N
O
2byj 1 P04181 99.77 0.0 X-RAY
 2005-09-07 TYR A:55 A:55 183.0 0.796 -136.1 154.0 59.0 0.257 0.539 B:P04181:0.539
 PLP
HOH
 6.567
3.203
 OH
OH
 O3P
O
TYR B:55 B:55 185.0 0.804 -135.6 153.9 57.0 0.248 0.556 A:P04181:0.557
 PLP
 6.703
 OH
 O3P
TYR C:55 C:55 182.0 0.791 -134.5 154.8 NA NA NA
2byl 1 P04181 99.32 0.0 X-RAY
 2005-09-07 ALA A:55 A:55 74.0 0.643 -92.6 156.7 13.0 0.113 0.53 B:P04181:0.53
 HOH
 2.849
 N
 O
ALA B:55 B:55 72.0 0.626 -92.9 169.3 11.0 0.096 0.53 A:P04181:0.53
 HOH
 2.943
 N
 O
ALA C:55 C:55 76.0 0.661 -93.6 172.3 NA NA NA
6hx7 1 P04181 99.76 0.0 X-RAY
 2019-06-05 TYR A:31 A:55 160.0 0.696 -127.0 151.4 38.0 0.165 0.531 A:P04181:0.53
 PLP
HOH
 6.647
2.276
 OH
OH
 O2P
O
TYR B:31 B:55 154.0 0.67 -131.6 151.4 NA NA NA
TYR C:31 C:55 158.0 0.687 -128.1 154.0 NA NA NA
5vwo 1 P04181 100.0 0.0 X-RAY
 2017-08-30 TYR A:20 A:55 178.0 0.774 -119.5 155.2 44.0 0.191 0.583 B:P04181:0.583
 9QJ
HOH
 6.461
2.447
 OH
OH
 O1F
O
TYR B:20 B:55 178.0 0.774 -118.6 154.8 45.0 0.196 0.578 A:P04181:0.578
 9QJ
HOH
 6.447
2.619
 OH
OH
 CEF
O
TYR C:20 C:55 175.0 0.761 -118.8 154.8 175.0 0.761 0.0 9QJ
HOH
 6.537
2.643
 OH
OH
 CEF
O
6oia 1 P04181 100.0 0.0 X-RAY
 2019-09-18 TYR A:20 A:55 167.0 0.726 -131.2 154.6 52.0 0.226 0.5 B:P04181:0.5
 PLP
HOH
 6.768
2.808
 OH
OH
 O1P
O
TYR B:20 B:55 162.0 0.704 -129.6 152.3 47.0 0.204 0.5 A:P04181:0.5
 PLP
MQ4
HOH
 6.753
2.412
2.677
 OH
OH
O
 O3P
O12
O
TYR C:20 C:55 167.0 0.726 -134.6 151.6 NA NA NA
6v8c 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:20 A:55 186.0 0.809 -128.4 158.5 63.0 0.274 0.535 A:P04181:0.535
 PLP
QRM
HOH
 6.791
2.688
2.677
 OH
OH
O
 O2P
O1
O
TYR B:20 B:55 182.0 0.791 -125.9 158.2 NA NA NA
TYR C:20 C:55 182.0 0.791 -129.2 158.2 NA NA NA
6v8d 1 P04181 100.0 0.0 X-RAY
 2020-12-16 TYR A:20 A:55 145.0 0.63 -122.0 156.8 35.0 0.152 0.478 B:P04181:0.478
 PLP
O78
HOH
 6.754
2.806
3.074
 OH
OH
OH
 O3P
O9
O
TYR B:20 B:55 165.0 0.717 -123.1 149.5 43.0 0.187 0.53 A:P04181:0.53
 PLP
O78
HOH
 6.615
2.801
3.192
 OH
OH
OH
 O2P
O8
O
TYR C:20 C:55 136.0 0.591 -127.1 157.4 NA NA NA
7jx9 1 P04181 100.0 0.0 X-RAY
 2021-01-06 TYR A:20 A:55 160.0 0.696 -126.7 155.9 45.0 0.196 0.5 A:P04181:0.5
 IF1
HOH
 2.441
2.957
 OH
O
 O27
O
TYR B:20 B:55 168.0 0.73 -128.1 152.7 NA NA NA
TYR C:20 C:55 155.0 0.674 -126.7 153.1 NA NA NA
7lnm 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:20 B:55 177.0 0.77 -132.0 154.3 56.0 0.243 0.527 B:P04181:0.526
 Y7S
HOH
 3.215
2.760
 OH
O
 O20
O
TYR B:20 C:55 184.0 0.8 -135.6 152.9 64.0 0.278 0.522 A:P04181:0.522
 Y7S
HOH
 4.837
3.063
 OH
N
 O19
O
TYR C:20 E:55 171.0 0.743 -131.1 153.9 NA NA NA
TYR D:20 F:55 178.0 0.774 -135.1 154.0 NA NA NA
TYR E:20 I:55 174.0 0.757 -132.3 154.2 NA NA NA
TYR F:20 J:55 176.0 0.765 -129.7 156.1 NA NA NA
7lom 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:20 A:55 167.0 0.726 -132.4 156.3 60.0 0.261 0.465 A:P04181:0.461
 THR
Y8P
HOH
 4.831
5.785
2.355
 OH
OH
OH
 N
C10
O
TYR B:20 B:55 164.0 0.713 -136.2 156.3 NA NA NA
TYR C:20 C:55 147.0 0.639 -136.5 151.8 NA NA NA
7lon 1 P04181 100.0 0.0 X-RAY
 2021-08-25 TYR A:20 B:55 163.0 0.709 -133.7 156.8 60.0 0.261 0.448 A:P04181:0.448
 THR
7QP
HOH
 4.876
2.935
2.551
 OH
OH
O
 N
O04
O
TYR B:20 A:55 162.0 0.704 -138.2 157.0 NA NA NA
TYR C:20 C:55 161.0 0.7 -133.5 156.9 NA NA NA
1gbn 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:18 A:55 174.0 0.757 -138.9 158.7 51.0 0.222 0.535 B:P04181:0.535
 GAB
PLP
HOH
 1.949
6.194
2.252
 HH
HH
H
 O2'
O3P
O
TYR B:18 B:55 175.0 0.761 -139.1 159.0 52.0 0.226 0.535 A:P04181:0.535
 GBC
PLP
HOH
 1.964
6.310
2.998
 HH
HH
OH
 O1
O3P
O
TYR C:18 C:55 173.0 0.752 -138.1 159.0 173.0 0.752 0.0 GBC
PLP
HOH
 2.397
6.102
2.847
 HH
HH
HH
 O1
O3P
O
2can 1 P04181 100.0 0.0 X-RAY
 1998-06-03 TYR A:18 A:55 121.0 0.526 -137.2 157.3 31.0 0.135 0.391 B:P04181:0.33
 CAN
PLP
HOH
 2.614
6.629
2.171
 OH
HH
HH
 N
O3P
O
TYR B:18 B:55 120.0 0.522 -137.8 156.7 28.0 0.122 0.4 A:P04181:0.339
 CAN
PLP
HOH
 2.867
6.691
2.348
 OH
HH
HH
 N
O3P
O
TYR C:18 C:55 123.0 0.535 -137.2 157.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04181-f1 1 P04181 100.0 0.0 TYR A:55 A:55 158.0 0.687 -126.3 154.5